CEBALLOS, L.; ALVAREZ, L.; LIFSCHITZ, A.; LANUSSE, C.

Ivermectin systemic availability in adult volunteers treated with different oral pharmaceutical formulations

BIOMEDICINE & PHARMACOTHERAPY = BIOMEDECINE & PHARMACOTHERAPIE.; Año: 2023 vol. 160

ICHINOSE, PAULA; MIRÓ, MARÍA VICTORIA; LARSEN, KAREN; LANUSSE, CARLOS; LIFSCHITZ, ADRIÁN; VIRKEL, GUILLERMO

Medication with fenbendazole in feed: plasma concentrations and effects on hepatic xenobiotic metabolizing enzymes in swine

VETERINARY RESEARCH COMMUNICATIONS; Año: 2023 vol. 47 p. 803 - 815

MIRÓ, MARÍA VICTORIA; COSTA-JÚNIOR, LIVIO MARTINS; LLOBERAS, MARÍA MERCEDES; CARDOZO, P.; LANUSSE, CARLOS EDMUNDO; VIRKEL G; LIFSCHITZ A

Phytochemicals in Gastrointestinal Nematode Control: Pharmacokinetic–Pharmacodynamic Evaluation of the Ivermectin plus Carvone Combination

Animals; Lugar: Basilea; Año: 2023 vol. 13 p. 1 - 14

JUAN, CANDELA; RODRIGUEZ, DAIANA; CEBALLOS, LAURA; LANUSSE, CARLOS; GALLO, LOREANA; GONZALEZ VIDAL, NOELIA

Development of ivermectin orally disintegrating tablets using factorial design: In-vitro evaluation and in vivo absorption pattern in rats

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY; Año: 2023 vol. 87

SUÁREZ, GONZALO; CASTELLS, DANIEL; IMPERIALE, FERNANDA; FAGIOLINO, PIETRO; CANTON, CANDELA; LANUSSE, CARLOS; ALVAREZ, LUIS

Therapeutic advantages of the combined use of closantel and moxidectin in lambs parasitized with resistant gastrointestinal nematodes

International Journal for Parasitology: Drugs and Drug Resistance; Año: 2023 vol. 23 p. 28 - 36

IGNACIO, ALVAREZ LUIS; VALENTINA, CHIAPPETTA; LUCILA, MORIONES; PAULA, DOMINGUEZ; CANDELA, CANTÓN; CARLOS, LANUSSE; LAURA, CEBALLOS

Feeding Management and Albendazole Pharmacokinetics in Pigs

Animals; Año: 2023 vol. 13

CANTON, CANDELA; CANTON, LUCILA; LIFSCHITZ, ADRIAN; PAULA DOMINGUEZ, MARIA; ALVAREZ, LUIS; CEBALLOS, LAURA; MATE, LAURA; LANUSSE, CARLOS; BALLENT, MARIANA

Monepantel-based anthelmintic combinations to optimize parasite control in cattle

INTERNATIONAL JOURNAL FOR PARASITOLOGY; Año: 2023 vol. 53 p. 441 - 449

CANTON, CANDELA; MUCHIUT, SEBASTIÁN; DOMINGUEZ, MARÍA PAULA; LANUSSE, CARLOS; ALVAREZ, LUIS IGNACIO; LIFSCHITZ, ADRIÁN

Comparative assessment of different ivermectin and doramectin formulations for mange control in grazing steers

VETERINARY PARASITOLOGY; Año: 2023 vol. 316

CANTÓN, GERMÁN; URTIZBIRÍA, FACUNDO; LLOBERAS, MARÍA MERCEDES; MORRELL, ELEONORA; LANUSSE, CARLOS; LIFSCHITZ, ADRIÁN

Iatrogenic doramectin overdosing causes toxicity in sheep: A case report

Veterinary Parasitology: Regional Studies and Reports; Año: 2022 vol. 30

MIRÓ, MARÍA VICTORIA; COSTA-JÚNIOR, LIVIO MARTINS; ALVAREZ, LUIS IGNACIO; LANUSSE, CARLOS; VIRKEL, GUILLERMO; LIFSCHITZ, ADRIÁN

Pharmacological characterization of geraniol in sheep and its potential use in the control of gastrointestinal nematodes

Veterinary and Animal Science; Año: 2022 vol. 18

CANTON, LUCILA; SIGNORINI, MARCELO; CANTON, CANDELA; DOMINGUEZ, PAULA; FARIAS, CRISTINA; ALVAREZ, LUIS; LANUSSE, CARLOS; MORENO, LAURA

Quantitative exposure assessment and risk characterization for fipronil residues in laying hen eggs

JOURNAL OF FOOD SCIENCE; Año: 2022 vol. 87 p. 2775 - 2788

MATE, LAURA; BALLENT, MARIANA; CANTÓN, CANDELA; LANUSSE, CARLOS; CEBALLOS, LAURA; ALVAREZ L, LUIS IGNACIO; LIRON, JUAN PEDRO

ABC-transporter gene expression in ivermectin-susceptible and resistant Haemonchus contortus isolates

VETERINARY PARASITOLOGY; Año: 2022 vol. 302

MORGAN, ERIC R.; LANUSSE, CARLOS; RINALDI, LAURA; CHARLIER, JOHANNES; VERCRUYSSE, JOZEF

Confounding factors affecting faecal egg count reduction as a measure of anthelmintic efficacy

PARASITE-JOURNAL DE LA SOCIETE FRANCAISE DE PARASITOLOGIE; Año: 2022 vol. 29

BALLENT, MARIANA; CANTON, CANDELA; DOMINGUEZ, PAULA; MATE, LAURA; CEBALLOS, LAURA; LANUSSE, CARLOS; LIFSCHITZ, ADRIAN

Pharmacokinetics and milk excretion pattern of eprinomectin at different dose rates in dairy cattle

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2022 vol. 45 p. 92 - 98

CANTON, CANDELA; CANTON, LUCILA; LIFSCHITZ, ADRIAN LUIS; DOMÍNGUEZ, MARÍA PAULA; TORRES, JUAN; LANUSSE, CARLOS EDMUNDO; ALVAREZ, LUIS IGNACIO; CEBALLOS, LAURA; BALLENT, MARIANA

Monepantel pharmaco-therapeutic evaluation in cattle: Pattern of efficacy against multidrug resistant nematodes

International Journal for Parasitology: Drugs and Drug Resistance; Año: 2021 vol. 15 p. 162 - 167

CANTON, LUCILA; CANTON, CANDELA; CEBALLOS, LAURA; DOMÍNGUEZ, MARÍA PAULA; RODRÍGUEZ, JOSÉ; LANUSSE, CARLOS EDMUNDO; ALVAREZ, LUIS IGNACIO; MORENO, LAURA

Oral and topical extra-label administration of fipronil to laying hens: Assessment of the egg residue patterns

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2021

MATAMOROS, GABRIELA; SÁNCHEZ, ANA; GABRIE, JOSÉ ANTONIO; JUÁREZ, MARISA; CEBALLOS, LAURA; ESCALADA, ANDRÉS; RODRÍGUEZ, CAROL; MARTÍ-SOLER, HELENA; RUEDA, MARÍA MERCEDES; CANALES, MARITZA; LANUSSE, CARLOS EDMUNDO; CAJAL, PAMELA; ÁLVAREZ, LUIS IGNACIO; CIMINO, RUBÉN O; KROLEWIECKI, ALEJANDRO

Efficacy and safety of albendazole and high-dose ivermectin co-administration in school-aged children infected with Trichuris trichiura in Honduras: A Randomized Controlled Trial

CLINICAL INFECTIOUS DISEASES; Lugar: Chicago; Año: 2021

CANTON, LUCILA; LANUSSE, CARLOS; MORENO, LAURA

Rational pharmacotherapy in infectious diseases: Issues related to drug residues in edible animal tissues

Animals; Lugar: Basel; Año: 2021 vol. 11

CEBALLOS, LAURA; NIEVES, E.; JUÁREZ, M.; AVELDAÑO, R.; TRAVACIO, M.; MARTOS, J.; CIMINO, R.; WALSON, J. L.; KROLEWIECKI, ALEJANDRO; LANUSSE, CARLOS EDMUNDO; ALVAREZ, LUIS IGNACIO

Assessment of diet-related changes on albendazole absorption, systemic exposure and pattern of urinary excretion in treated human volunteers.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2021

LUQUE, SONIA; LLOBERAS, MERCEDES; CARDOZO, P.; VIRKEL, GUILLERMO LEÓN; FARIAS, CRISTINA ; VIVIANI, PAULA; LANUSSE, CARLOS EDMUNDO; ALVAREZ, LUIS IGNACIO; LIFSCHITZ, ADRIAN LUIS

Combined moxidectin-levamisole treatment against multidrug-resistant gastrointestinal nematodes: A four-year efficacy monitoring in lambs

VETERINARY PARASITOLOGY; Año: 2021 vol. 290

KROLEWIECKI, ALEJANDRO; LIFSCHITZ, ADRIÁN LUIS; MORAGAS, MATÍAS; TRAVACIO, MARINA; VALENTINI, RICARDO; ALONSO, DANIEL F.; SOLARI, RUBÉN; TINELLI, MARCELO A.; CIMINO, RUBÉN O.; ÁLVAREZ, LUIS IGNACIO; FLEITAS, PEDRO E.; CEBALLOS, LAURA; GOLEMBA, MARCELO; FERNÁNDEZ, FLORENCIA; FERNÁNDEZ DE OLIVEIRA, DIEGO; ASTUDILLO, GERMAN; BAECK, INÉS; FARINA, JAVIER; CARDAMA, GEORGINA A.; MANGANO, ANDREA; SPITZER, EDUARDO; GOLD, SILVIA; LANUSSE, CARLOS

Antiviral effect of high-dose ivermectin in adults with COVID-19: A proof-of-concept randomized trial

EClinicalMedicine; Año: 2021 vol. 37

ERRECALDE, JORGE; LIFSCHITZ, ADRIAN LUIS; VECCHIOLI, GRACIELA; CEBALLOS, LAURA; ERRECALDE, FRANCISCO; BALLENT, MARIANA; MARÍN, GUSTAVO; DANIELE, MARTÍN; TURIC, ESTEBAN; SPITZER, EDUARDO; TONEGUZZO, FERNANDO; GOLD, SILVIA; KROLEWIECKI, ALEJANDRO; ALVAREZ, LUIS IGNACIO; LANUSSE, CARLOS EDMUNDO

Safety and Pharmacokinetic Assessments of a Novel Ivermectin Nasal Spray Formulation in a Pig Model

JOURNAL OF PHARMACEUTICAL SCIENCES; Año: 2021 vol. 110 p. 2501 - 2507

JERMAIN, BRIAN; HANAFIN, PATRICK O.; CAO, YANGUANG; LIFSCHITZ, ADRIAN LUIS; LANUSSE, CARLOS EDMUNDO; RAO, GAURI G.

Development of a Minimal Physiologically-Based Pharmacokinetic Model to Simulate Lung Exposure in Humans Following Oral Administration of Ivermectin for COVID-19 Drug Repurposing

JOURNAL OF PHARMACEUTICAL SCIENCES; Año: 2020 vol. 109 p. 3574 - 3578

PAREDES, ALEJANDRO J.; CAMACHO, NAHUEL M.; SCHOFS, LAUREANO; DIB, ALICIA; ZARAZAGA, MARÍA DEL PILAR; LITTERIO, NICOLÁS; ALLEMANDI, DANIEL A.; SÁNCHEZ BRUNI, SERGIO FABIAN; LANUSSE, CARLOS EDMUNDO; PALMA, SANTIAGO D.

Ricobendazole nanocrystals obtained by media milling and spray drying: Pharmacokinetic comparison with the micronized form of the drug

INTERNATIONAL JOURNAL OF PHARMACEUTICS; Año: 2020 vol. 585

CANTÓN, CANDELA; CEBALLOS, LAURA; DOMÍNGUEZ, MARÍA PAULA; FIEL, CÉSAR; LIRÓN, JUAN PEDRO; MORENO, LAURA; CANTON, LUCILA; BERNAT, GISELE; LANUSSE, CARLOS EDMUNDO; ALVAREZ, LUIS IGNACIO

Impact on beef cattle productivity of infection with anthelmintic-resistant nematodes

NEW ZEALAND VETERINARY JOURNAL; Año: 2020 vol. 68 p. 187 - 192

MIRÓ, MARÍA VICTORIA; E SILVA, CAROLINA ROCHA; VIVIANI, PAULA; LUQUE, SONIA; LLOBERAS, MERCEDES; COSTA-JÚNIOR, LIVIO MARTINS; LANUSSE, CARLOS EDMUNDO; VIRKEL, GUILLERMO LEÓN; LIFSCHITZ, ADRIÁN LUIS

Combination of bioactive phytochemicals and synthetic anthelmintics: In vivo and in vitro assessment of the albendazole-thymol association

VETERINARY PARASITOLOGY; Año: 2020 vol. 281

MIRÓ, VICTORIA; LIFSCHITZ, ADRIAN LUIS; VIVIANI, PAULA; ROCHA, CAROLINA; LANUSSE, CARLOS EDMUNDO; COSTA, LIVIO; VIRKEL, GUILLERMO LEÓN

In vitro inhibition of the hepatic S-oxygenation of the anthelmintic albendazole by the natural monoterpene thymol in sheep

XENOBIOTICA; Año: 2020 vol. 50 p. 408 - 414

BALLENT, MARIANA; CANTON, CANDELA; DOMINGUEZ, PAULA; BERNAT, GISELE; LANUSSE, CARLOS E.; VIRKEL, GUILLERMO LEÓN; LIFSCHITZ, ADRIAN LUIS

Pharmacokinetic-pharmacodynamic assessment of the ivermectin and abamectin nematodicidal interaction in cattle

VETERINARY PARASITOLOGY; Año: 2020 vol. 279

LARROZA, M.; SOLER, P.; ROBLES, C.; CABRERA, R.; BALLENT, M.; LANUSSE, C.; LIFSCHITZ, A.

Doramectin efficacy against Psoroptes ovis in sheep: Evaluation of pharmacological strategies

EXPERIMENTAL PARASITOLOGY; Año: 2020 vol. 218

CEBALLOS, LAURA; CANTON, CANDELA; PRUZZO, CESAR; SANABRIA, RODRIGO; MORENO, LAURA; SANCHIS, JAIME; SUAREZ, GONZALO; ORTIZ, PEDRO; FAIRWEATHER, IAN; LANUSSE, CARLOS; ALVAREZ, LUIS; VALLADARES, MARÍA MARTINEZ

The egg hatch test: A useful tool for albendazole resistance diagnosis in Fasciola hepatica

VETERINARY PARASITOLOGY; Año: 2019 vol. 271 p. 7 - 13

FAZZIO, LUIS; MORENO, LAURA; GALVAN, WALTER; CANTON, CANDELA; ALVAREZ, LUIS; STREITENBERGER, NICOLÁS; SÁNCHEZ, RICARDO; LANUSSE, CARLOS; SANABRIA, RODRIGO

Pharmacokinetic profile and anthelmintic efficacy of moxidectin administered by different doses and routes to feedlot calves

VETERINARY PARASITOLOGY; Año: 2019 vol. 266 p. 73 - 79

BALLENT, MARIANA; MATÉ, MARIA LAURA; DOMINGUEZ, PAULA; VIRKEL, GUILLERMO; ALBÉRICH, MELANIE; LESPINE, ANNE; LANUSSE, CARLOS; LIFSCHITZ, ADRIAN LUIS

Assessment of the long-acting ivermectin formulation in sheep: Further insight into potential pharmacokinetic interactions

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2019 vol. 42 p. 189 - 196

CANTON, LUCILA; ALVAREZ, LUIS; CANTON, CANDELA; CEBALLOS, LAURA; FARIAS, CRISTINA; LANUSSE, CARLOS; MORENO, LAURA

Effect of cooking on the stability of veterinary drug residues in chicken eggs

Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment; Año: 2019 vol. 36 p. 1055 - 1067

CEBALLOS, LAURA; CANTON, CANDELA; CADENAZZI, GABRIELA; VIRKEL, GUILLERMO; DOMINGUEZ, PAULA; MORENO, LAURA; LANUSSE, CARLOS; ALVAREZ, LUIS

Oxfendazole kinetics in pigs: In vivo assessment of its pattern of accumulation in Ascaris suum

EXPERIMENTAL PARASITOLOGY; Año: 2019 vol. 199 p. 52 - 58

LARSEN, KAREN E.; LIFSCHITZ, ADRIÁN L.; LANUSSE, CARLOS E.; VIRKEL, GUILLERMO L.

In vitro and in vivo effects of chlorpyrifos and cypermethrin on blood cholinesterases in sheep

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2019 vol. 42 p. 548 - 555

MATÉ, L.; GIANTIN, M.; VIVIANI, P.; BALLENT, M.; TOLOSI, R.; LIFSCHITZ, A.; LANUSSE, C.; DACASTO, M.; VIRKEL, G.

Effects of fenbendazole and triclabendazole on the expression of cytochrome P450 1A and flavin-monooxygenase isozymes in bovine precision-cut liver slices

The Veterinary Journal; Año: 2019 vol. 245 p. 61 - 69

VIVIANI, P.; LIFSCHITZ, A.L.; LUQUE, S.E.; LLOBERAS, M.M.; MATÉ, M.L.; CARDOZO, P.A.; LANUSSE, C.E.; VIRKEL, G.L.

Pharmacologic interaction between oxfendazole and triclabendazole: In vitro biotransformation and systemic exposure in sheep

EXPERIMENTAL PARASITOLOGY; Año: 2019 vol. 204

VIRKEL, GUILLERMO; BALLENT, MARIANA; LANUSSE, CARLOS; LIFSCHITZ, ADRIÁN

Role of ABC transporters in veterinary medicine: Pharmaco-toxicological implications

CURRENT MEDICINAL CHEMISTRY.; Año: 2019 vol. 26 p. 1251 - 1269

NAVA S,; ROSSNER M V; BALLENT M; MANGOLD A,; LANUSSE C.; LIFSCHITZ A.

Relationship between pharmacokinetics of ivermectin (3.15%) and its efficacy to control the infestation with the tick Rhipicephalus (Boophilus) microplus in cattle

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2019 vol. 68 p. 81 - 86

LANUSSE, CARLOS; CANTON, CANDELA; VIRKEL, GUILLERMO; ALVAREZ, LUIS; COSTA-JUNIOR, LIVIO; LIFSCHITZ, ADRIAN

Strategies to Optimize the Efficacy of Anthelmintic Drugs in Ruminants

TRENDS IN PARASITOLOGY; Año: 2018 vol. 34 p. 664 - 682

LIFSCHITZ, A.; FIEL, C.; STEFFAN, P.; CANTÓN, C.; MUCHIUT, S.; DOMINGUEZ, P.; LANUSSE, C.; ALVAREZ, L.

Failure of ivermectin efficacy against Psoroptes ovis infestation in cattle: Integrated pharmacokinetic-pharmacodynamic evaluation of two commercial formulations

VETERINARY PARASITOLOGY; Año: 2018 vol. 263 p. 18 - 22

PAREDES, ALEJANDRO J; BRUNI, SERGIO SÁNCHEZ; ALLEMANDI, DANIEL; LANUSSE, CARLOS; PALMA, SANTIAGO D

Albendazole nanocrystals with improved pharmacokinetic performance in mice

Therapeutic Delivery; Lugar: Londres; Año: 2018 vol. 9 p. 89 - 97

VIVIANI, P.; LIFSCHITZ, A.L.; MATÉ, M.L.; GARCÍA, J.P.; LANUSSE, C.E.; VIRKEL, G.L.

Assessment of the pharmacological interactions between the nematodicidal fenbendazole and the flukicidal triclabendazole: In vitro studies with bovine liver microsomes and slices

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2018 vol. 41 p. 476 - 484

CANTON, CANDELA; CANTON, LUCILA; DOMÍNGUEZ, MARÍA PAULA; MORENO, LAURA; LANUSSE, CARLOS; ALVAREZ, LUIS; CEBALLOS, LAURA

Field trial assessment of ivermectin pharmacokinetics and efficacy against susceptible and resistant nematode populations in cattle

VETERINARY PARASITOLOGY; Año: 2018 vol. 256 p. 43 - 49

MORENO, LAURA; BISTOLETTI, MARIANA; FERNÁNDEZ, HECTOR; CANTÓN, LUCILA; CEBALLOS, LAURA; CANTÓN, CANDELA; LANUSSE, CARLOS; ÁLVAREZ, LUIS I.

Albendazole treatment in laying hens: Egg residues and its effects on fertility and hatchability

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2018 vol. 41 p. 726 - 733

MATÉ, L.; BALLENT, M.; CANTÓN, C.; CEBALLOS, L.; LIFSCHITZ, A.; LANUSSE, C.; ALVAREZ, L.; LIRON, J.P.

Assessment of P-glycoprotein gene expression in adult stage of Haemonchus contortus in vivo exposed to ivermectin

VETERINARY PARASITOLOGY; Año: 2018 vol. 264 p. 1 - 7

PAREDES, ALEJANDRO JAVIER; LITTERIO, NICOLÁS; DIB, ALICIA; ALLEMANDI, DANIEL ALBERTO; LANUSSE, CARLOS; BRUNI, SERGIO SÁNCHEZ; PALMA, SANTIAGO DANIEL

A nanocrystal-based formulation improves the pharmacokinetic performance and therapeutic response of albendazole in dogs

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 2018 vol. 70 p. 51 - 58

BALLENT, M.; VIVIANI, P.; IMPERIALE, F.; DOMINGUEZ, P.; HALWACHS, S.; MAHNKE, H.; HONSCHA, W.; LANUSSE, C.; VIRKEL, G.; LIFSCHITZ, A.

Pharmacokinetic assessment of the monepantel plus oxfendazole combined administration in dairy cows

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2018 vol. 41 p. 292 - 300

CEBALLOS, LAURA; KROLEWIECKI, ALEJANDRO; JUÁREZ, MARISA; MORENO, LAURA; SCHAER, FABIAN; ALVAREZ, LUIS I.; CIMINO, RUBÉN; WALSON, JUDD; LANUSSE, CARLOS E.

Assessment of serum pharmacokinetics and urinary excretion of albendazole and its metabolites in human volunteers

PLOS NEGLECTED TROPICAL DISEASES; Lugar: San Francisco; Año: 2018 vol. 12

CANTON, C.; CEBALLOS, L.; DOMÍNGUEZ, M.P.; MORENO, L.; FIEL, C.; BERNAT, G.; FARÍAS, C.; LANUSSE, C.; ALVAREZ, L.

Pharmaco-parasitological evaluation of the ricobendazole plus levamisole nematodicidal combination in cattle

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2018 vol. 41 p. 83 - 91

PAREDES, ALEJANDRO JAVIER; LITTERIO, NICOLÁS; DIB, ALICIA; ALLEMANDI, DANIEL ALBERTO; LANUSSE, CARLOS; BRUNI, SERGIO SÁNCHEZ; PALMA, SANTIAGO DANIEL

A nanocrystal-based formulation improves the pharmacokinetic performance and therapeutic response of albendazole in dogs

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 2018 vol. 70 p. 51 - 58

BALLENT, M.; VIVIANI, P.; IMPERIALE, F.; DOMINGUEZ, P.; HALWACHS, S.; MAHNKE, H.; HONSCHA, W.; LANUSSE, C.; VIRKEL, G.; LIFSCHITZ, A.

Pharmacokinetic assessment of the monepantel plus oxfendazole combined administration in dairy cows

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2017

CEBALLOS, L.; CANTON, C.; CADENAZZI, G.; LARSEN, K.; VIRKEL, G.; MORENO, L.; FAIRWEATHER, I.; LANUSSE, C.; ALVAREZ, L.

Understanding the main route of drug entry in adult Fasciola hepatica: Further insights into closantel pharmacological activity

EXPERIMENTAL PARASITOLOGY; Año: 2017 vol. 181 p. 23 - 29

CANTON, C., CEBALLOS, L., FIEL, C., MORENO, L., DOMINGO YAGÜEZ, P., BERNAT, G., LANUSSE, C., ALVAREZ, L.

Resistant nematodes in cattle: Pharmaco-therapeutic assessment of the ivermectin- ricobendazole combination

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2017 vol. 234 p. 40 - 48

VIVIANI, PAULA; LIFSCHITZ, ADRIÁN L.; GARCÍA, JORGE P.; MATÉ, MARÍA LAURA; QUIROGA, MIGUEL A.; LANUSSE, CARLOS E.; VIRKEL, GUILLERMO L.

Assessment of liver slices for research on metabolic drug–drug interactions in cattle

XENOBIOTICA; Año: 2017 p. 1 - 10

SAUMELL, C., LIFSCHITZ, A., BARONI, R., FUSÉ, L., BISTOLETTI, M., SAGÜES, F., BRUNO, S., ALVAREZ, G., LANUSSE, C., ALVAREZ, L

The route of administration drastically affects ivermectin activity against small strongyles in horses.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2017 vol. 236 p. 62 - 67

ML MATÉ, T GEARY, C MACKENZIE, C LANUSSE, G VIRKEL ; LANUSSE C

Species differences in hepatic biotransformation of the anthelmintic drug flubendazole

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2017

IEZZI, SEBASTIAN; PURSLOW, PETER; SARA, CHRISTENSEN; LANUSSE, CARLOS; LIFSCHITZ, ADRIAN

Relationship between ivermectin concentrations at the injection site, muscle and fat of steers treated with traditional and long-acting preparations

FOOD AND CHEMICAL TOXICOLOGY; Año: 2017 vol. 105 p. 319 - 321

. A LIFSCHITZ, C LANUSSE, L ALVAREZ ; LANUSSE C; ALVAREZ L

Host pharmacokinetics and drug accumulation of anthelmintics within target helminth parasites of ruminants

NEW ZEALAND VETERINARY JOURNAL; Año: 2017 p. 1 - 25

MAHNKE, H; BALLENT, M; BAUMANN, S; IMPERIALE, F; VON BERGEN, M; LANUSSE, C; LIFSCHITZ, A; HONSCHA, W

The ABCG2 efflux transporter in the mammary gland mediates veterinary drug secretion across the blood-milk barrier into milk of dairy cows.

Drug Metabolism and Disposition; Lugar: Baltimore; Año: 2016 vol. 44 p. 700 - 700

TARBIAT B.; MORENO L.; LANUSSE C.; TYDEN S

The efficacy of flubendazole against different developmental stages of the poultry roundworm Ascaridia galli in laying hens

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2016 vol. 218 p. 66 - 72

LIFSCHITZ A.; NAVA S,; MANGOLD A,; IMPERIALE F; CANEVARI, J; LANUSSE C.

Eprinomectin accumulation in Rhipicephalus (Boophilus) microplus: Pharmacokinetic and efficacy assessment

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2016 vol. 215 p. 11 - 16

LARSEN, K; LIFSCHITZ A.; LANUSSE C.; VIRKEL G.

The herbicide glyphosate is a weak inhibitor of acetylcholinesterase in rats

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY; Lugar: Amsterdam; Año: 2016 vol. 45 p. 41 - 44

BALLENT, M; VIRKEL, G; MATE, L; VIVIANI, P; LANUSSE, C; LIFSCHITZ A

Hepatic biotransformation pathways and ruminal metabolic stability of the novel anthelmintic monepantel in sheep and cattle.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2016 vol. 39 p. 488 - 496

GAMBOA, G.V.U.; PALMA, S.D; LIFSCHITZ, A; BALLENT, M; LANUSSE, C; PASSIRANI, C; BENOIT, J.P; ALLEMANDI, D.A

Ivermectin-loaded lipid nanocapsules: toward the development of a new antiparasitic delivery system for veterinary applications.

PARASITOLOGY RESEARCH; Lugar: Berlin; Año: 2016 vol. 115 p. 1945 - 1953

LANUSSE, C ; ALVAREZ L.; LIFSCHITZ A.

Gaining Insights Into the Pharmacology of Anthelmintics Using Haemonchus contortus as a Model Nematode

ADVANCES IN PARASITOLOGY.; Lugar: Burlington, MA, Estados Unidos; Año: 2016 vol. 93 p. 465 - 518

IMPERIALE J; NEJAMKIN, P; DEL SOLE, M J; LANUSSE, C; SOSNIK, A

Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs

BIOMATERIALS; Lugar: Amsterdam; Año: 2015

MATÉ L; BALLENT, M; LARSEN, K; LIFSCHITZ, A; LANUSSE, C; VIRKEL, G

Gene expression and enzyme function of two cytochrome P450 3A isoenzymes in rat and cattle precision cut liver slices

XENOBIOTICA; Lugar: Londres; Año: 2015

CEBALLOS, L; ALVAREZ, L; MACKENZIE, C; GEARY, A; LANUSSE, C

Pharmacokinetic comparison of different flubendazole formulations in pigs: A further contribution to its development as a macrofilaricide molecule

INTERNATIONAL JOURNAL FOR PARASITOLOGY; Lugar: Amsterdam; Año: 2015 vol. 5 p. 178 - 184

CEBALLOS, LAURA; ELISSONDO, CELINA; SANCHEZ BRUNI, SERGIO; DENEGRI, GUILLERMO; LANUSSE, CARLOS; ALVAREZ, LUIS

Combined flubendazole-nitazoxanide treatment of cysticechinococcosis: Pharmacokinetic and efficacy assessment in mice.

ACTA TROPICA; Lugar: Amsterdam; Año: 2015 vol. 148 p. 89 - 96

LANUSSE, CARLOS E; LIFSCHITZ, ADRIAN; ALVAREZ, LUIS

Basic and clinical pharmacology contribution to extend anthelmintic molecules lifespan.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2015 vol. 212 p. 35 - 46

LLOBERAS, M; ALVAREZ, L; ENTROCASSO, C; BALLENT, M; VIRKEL, G; LUQUE, S; LANUSSE, C; LIFSCHITZ, A

Comparative pharmacokinetic and pharmacodynamic response of single and double intraruminal doses of ivermectin and moxidectin in nematode-infected lambs

NEW ZEALAND VETERINARY JOURNAL; Año: 2015

MORENO TORREJÓN, L; DOMINGUEZ, P; FARIAS, C; CANTON, C; VIRKEL G,; LANUSSE C.

Ivermectin Pharmacokinetics, Metabolism, and Tissue/Egg Residue Profiles in Laying Hens.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY; Lugar: Washington; Año: 2015 vol. 63 p. 10327 - 10332

ALICIA, DIB; ALEJANDRO, PAREDES; NATASHA, ELIÓPULOS; LANUSSE C.; SANCHEZ BRUNI S

Pharmacokinetic Assessment of Novel Controlled Release Formulations of Ricobendazole Intended for Oral Administration in Dogs

Clinical & Experimental Pharmacology; Año: 2015 vol. 05

ALVAREZ, L; SUAREZ G; CEBALLOS L; MORENO, L; CANTON, C; LIFSCHITZ, A.; MATÉ L; BALLENT, M; VIRKEL, G.,; LANUSSE, C

Integrated assessment of ivermectin pharmacokinetics, efficacy against resistant Haemonchus contortus and P-glycoprotein expression in lambs treated at three different dosage levels

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2015

BISTOLETTI, M; ALVAREZ L,; LANUSSE, C; MORENO, L

EFFECTS OF FEEDING ON THE PLASMA DISPOSITION KINETICS OF THE ANTHELMINTIC ALBENDAZOLE IN LAYING HENS

BRITISH POULTRY SCIENCE; Lugar: Londres; Año: 2014

ORTIZ, P; CASTOPE, N; CABRERA, M; FARIAS, C; SUAREZ, G; LANUSSE, C; ALVAREZ, L

Pharmacokinetic evaluation of different generic triclabendazole formulations in heifers

NEW ZEALAND VETERINARY JOURNAL; Año: 2014

LARSEN, K; NAJLE, R; LIFSCHITZ, A; MATÉ, L; LANUSSE, C; VIRKEL, G

Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats

INTERNATIONAL JOURNAL OF TOXICOLOGY; Lugar: Thousand Oaks, California.; Año: 2014

LISCHITZ, A; BALLENT, M; VIRKEL, G ; SALLOVITZ, J; VIVIANI, P; LANUSSE, C

Accumulation of monepantel and its sulphone derivative in tissues of nematode location in sheep: Pharmacokinetic support to its excellent nematodicidal activity.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2014

SUAREZ, G; ALVAREZ, L; CASTELLS, D; MORENO, L; FAGIOLINO, P; LANUSSE, C

Evaluation of pharmacological interactions after administration of a levamisole, albendazole and ivermectin triple combination in lambs

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2014

VIRKEL, G; LIFSCHITZ, A; SALLOVITZ, J; MATÉ, L; FARÍAS, C; LANUSSE, C

In vitro and in vivo assessment of the benzydamine-mediatedinterference with the hepatic S-oxidation of the anthelminticalbendazole in sheep.

JOURNAL OF SMALL RUMINANT RESEARCH; Lugar: Amsterdam; Año: 2014

IEZZI, S; LIFSCHITZ, A; SALLOVITZ, J; NEJAMKIN, P; LLOBERAS, M; MANAZZA, J; LANUSSE, C

Closantel plasma and milk disposition in dairy goats: assessment of drug residues in cheese and ricotta.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2014

LANUSSE, C; ALVAREZ, L; LIFSCHITZ, A

Pharmacological knowledege and sustainable anthelmintic therapy in ruminants.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2014

BALLENT, M; MATÉ, L; VIRKEL, G; SALLOVITZ, J; VIVIANI, P; LANUSSE, C; LIFSCHITZ, A

Intestinal drug transport: ex vivo evaluation of the interactions between ABC transporters and anthelmintic molecules

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2014

MORENO, L; CEBALLOS, L; FAIRWEATHER, I; LANUSSE, C; ALVAREZ, L

Time-course and accumulation of triclabendazole and its metabolites in bile, liver tissues and flukes collected from treated sheep.

EXPERIMENTAL PARASITOLOGY; Lugar: Amsterdam; Año: 2014 vol. 136 p. 14 - 19

ORTIZ, P; TERRONES, S; CABRERA, M; HOBAN, C; CEBALLOS, L; MORENO, L; CANTON, C; DONADEU, M; LANUSSE, C; ALVAREZ, L

Oxfendazole flukicidal activity in pigs.

ACTA TROPICA; Lugar: Amsterdam; Año: 2014

CEBALLOS, L; MACKENZIE, C; GEARY, A; ALVAREZ, L; LANUSSE, C

Exploring the Potential of Flubendazole in Filariasis Control: Evaluation of the Systemic Exposure for Different Pharmaceutical Preparations

PLOS NEGLECTED TROPICAL DISEASES; Lugar: San Francisco; Año: 2014

SANABRIA, R; MORENO, L; ALVAREZ, L; LANUSSE, C; ROMERO, J

Efficacy of oxyclozanide against adult Paramphistomumleydeni in naturally infected sheep.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2014 vol. 206 p. 277 - 281

BISTOLETTI, M; ALVAREZ, L; MORENO, L; LANUSSE, C

Disposition kinetics of albendazole and metabolites in laying hens.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2013 vol. 36 p. 161 - 168

BALLENT, M; WILKENS, M; MATÉ, L.; MUSCHER, A; VIRKEL, G; SALLOVITZ, J; SCHRÖDER, B; LANUSSE, C; LIFSCHITZ, A

P-glycoprotein in sheep liver and small intestine: Gene expression and transport efflux activity

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2013 vol. 36 p. 576 - 582

CANEVARI, J; CEBALLOS, L; SANABRIA, R; ROMERO, J; OLAECHEA, F; ORTIZ, P; CABRERA, M; GAYO, V; FAIRWEATHER, I; LANUSSE, C; ALVAREZ, L

Testing albendazole resistance in Fasciola hepatica: validation of an egg hatch test with isolates from South America and the United Kingdom.

JOURNAL OF HELMINTHOLOGY; Lugar: Cambridge; Año: 2013 vol. 19 p. 1 - 7

ALVAREZ, L; SAUMELL, C; FUSÉ, L; MORENO, L; CEBALLOS, L; DOMINGUE, G; DONADEU, M; DUNGU, B; LANUSSE, C

Efficacy of a single high oxfendazole dose against gastrointestinal nematodes in naturally infected pigs.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2013 p. 70 - 74

SANABRIA, R; CEBALLOS, L; MORENO, L; ROMERO, J; LANUSSE, C; ALVAREZ, L

Identification of a field isolate of Fasciola hepatica resistant to albendazole and susceptible to triclabendazole.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2013 p. 105 - 110

LLOBERAS, M; ALVAREZ, L; ENTROCASSO, C; VIRKEL, G; BALLENT, M; MATÉ, L; LANUSSE, C; LIFSCHITZ, A

Comparative tissue pharmacokinetics and efficacy of moxidectin, abamectin and ivermectin in lambs infected with resistant nematodes: Impact of drug treatments on parasite P-glycoprotein expression

INTERNATIONAL JOURNAL FOR PARASITOLOGY; Lugar: Amsterdam; Año: 2013 p. 20 - 27

CASTRO, S; DIB, A; SUAREZ, G; ALLEMANDI, D; LANUSSE, C; SANCHEZ BRUNI, S; PALMA, S

Comparative plasma exposure of albendazole after administration of rapidly disintegrating tablets in dogs.

BioMed Research International; Lugar: Londres; Año: 2013 p. 1 - 7

SUAREZ, G; ALVAREZ, L; CASTELLS, D; CORREA, O; FIGIOLINO, P; LANUSSE, C

Relative bioavailability and comparative clinical efficacy of different ivermectin oral formulations in lambs.

BMC VETERINARY RESEARCH; Lugar: Londres; Año: 2013 p. 9 - 27

CEBALLOS, L; VIRKEL, G; ELISSONDO, C; CANTON, C; CANEVARI, J; MURNO, C; DENEGRI, G; LANUSSE, C; ALVAREZ, L

A pharmacology-based comparison of the activity of albendazole andflubendazole against Echinococcus granulosus metacestode in sheep

ACTA TROPICA; Lugar: Amsterdam; Año: 2013 p. 216 - 225

DEL SOLE, M J; SCHAIQUEVICH, P; ABA, M; LANUSSE, C; MORENO, L

Plasma and Ocular Prednisolone Disposition after Oral Treatment in Cats

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY; Lugar: New York; Año: 2013 p. 1 - 6

CASTRO, S; SANCHEZ BRUNI, S; URBIZU, L; CONFALONIERI, A; CEBALLOS, L; LANUSSE, C; ALLEMANDI, D; PALMA, S

Enhanced dissolution and systemic availability of albendazole formulated as solid dispersions.

PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY; Lugar: Londres; Año: 2013 vol. 18 p. 432 - 444

TOUTAIN, P-L; MODRIC, S; BOUSQUET-ME´LOU; SALLOVITZ J; LANUSSE, C

Should licking behavior be considered in the bioavailability evaluation of transdermal products?

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2012 vol. 1 p. 39 - 43

LIFSCHITZ A; BALLENT M; LANUSSE C.

Macrocyclic lactones and cellular transport-related drug interactions -A perspective from in vitro assays to nematode control in the field.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY; Lugar: Oak Park; Año: 2012 vol. 13 p. 912 - 923

DEVINE C; BRENNAN G; LANUSSE, C; ALVAREZ, L; TRUDGETT A.,; HOEY E; FAIRWEATHER I

Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2012 p. 37 - 47

LLOBERAS, M; ALVAREZ L; ENTROCASSO, C; VIRKEL G; LANUSSE C; LIFSCHITZ A

Measurement of ivermectin concentrations in target worms and host gastrointestinal tissues: influence of the route of administration on the activity against resistant Haemonchus contortus in lambs

EXPERIMENTAL PARASITOLOGY; Lugar: Amsterdam; Año: 2012

ALVAREZ, L; SUAREZ G; CEBALLOS L; MORENO L; LANUSSE C

Dose-dependent systemic exposure of albendazole metabolites in lambs.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2012 vol. 35 p. 365 - 372

MATÉ L; LIFSCHITZ, A.; SALLOVITZ J,; BALLENT M,; MUSCHER, A.; WILKENS, M.; SCHRODER, B; LANUSSE, C; VIRKEL G.

Cytochrome P450 3A expression and function in liver and intestinal mucosa from dexamethasone-treated sheep

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2012 vol. 35 p. 319 - 328

BARRÈRE V; ALVAREZ L; SUAREZ G; CEBALLOS L; MORENO L; LANUSSE C; PRICHARD R

Relationship between increased albendazole systemic exposure and changes in single nucleotide polymorphisms on the β-tubulin isotype 1 encoding gene in Haemonchus contortus.

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2012 p. 344 - 349

URBIZU, L; CONFALONIERI, A; SANCHEZ BRUNI S; LANUSSE, C; ALVAREZ, I

Nematodicidal activity of flubendazole and its reduced metabolite on a murine model of Trichinella spiralis Infection.

CHEMOTHERAPY; Lugar: Basel; Año: 2012 vol. 58 p. 295 - 298

MORENO, L; LOPEZ-URBINA, L; FARIAS, C; DOMINGUE, G; DONADEU, M; DUNGU, B; GARCIA, H; GOMEZ-PUERTA, L; LANUSSE, C; GONZALEZ, A

A high oxfendazole dose to control porcine cysticercosis: Pharmacokinetics and tissue residue profiles

FOOD AND CHEMICAL TOXICOLOGY; Lugar: Amsterdam; Año: 2012 vol. 50 p. 3819 - 3825

CEBALLOS, L; MORENO, L; TORRADO, J; LANUSSE, C; ALVAREZ, L

Exploring flubendazole formulations for use in sheep. Pharmacokinetic evaluation of a cyclodextrin-based solution.

BMC VETERINARY RESEARCH; Lugar: Londres; Año: 2012 vol. 8 p. 71 - 78

BISTOLETTI, M; MORENO L; ALVAREZ L,; LANUSSE, C

Multiresidue HPLC method to measure benzimidazole anthelmintics in plasma and egg from laying hens. Evaluation of albendazole metabolites residue profiles.

FOOD CHEMISTRY; Lugar: Amsterdam; Año: 2011 p. 793 - 800

IMPERIALE, F.; ORTIZ, P; CABRERA, M; FARIAS, C; SALLOVITZ J,; IEZZI, S; PÉREZ, J; ALVAREZ L,; LANUSSE C,

Residual concentrations of the flukicidal compound triclabendazole in dairy cows' milk and cheese

Food Additives & Contaminants; Lugar: London; Año: 2011 vol. 28 p. 438 - 445

SALLOVITZ J; NEJAMKIN, P; LIFSCHITZ, A; VIRKEL G.; IMPERIALE F,; LANUSSE C,

Comparative in vitro characterization of moxidectin and doramectin percutaneous absorption through bovine skin.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2011 p. 184 - 192

DIB, A; PALMA S; SUAREZ G; FARIAS, C; CABRERA, P; CASTRO, S; ALLEMANDI, D; MORENO, L; LANUSSE, C; SANCHEZ BRUNI, S

Albendazole sulphoxide kinetic disposition after treatment with different formulations in dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2011 p. 136 - 141

DEVINE C; BRENNAN G; LANUSSE, C; ALVAREZ, L; TRUDGETT E.; HOEY E; FAIRWEATHER I

Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica.

PARASITOLOGY RESEARCH; Lugar: Berlin; Año: 2011 p. 981 - 995

DEVINE C; BRENNAN G; LANUSSE. C; ALVAREZ L.; TRUDGETT E.; HOEY E; FAIRWEATHER I

Enhancement of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica by co-treatment with ketoconazole

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2011 vol. 177 p. 305 - 315

BALLENT M; LIFSCHITZ, A; VIRKEL, G; SALLOVITZ, J; MATÉ L; LANUSSE, C

In vivo and ex vivo assessment of the interaction between ivermectin and danofloxacin in sheep.

The Veterinary Journal; Lugar: Amsterdam; Año: 2011

SUAREZ G; ALVAREZ,L; CASTELLS, D; CORREA, O; FAGIOLINO P; LANUSSE, C

Comparative drug systemic exposure and clinical efficacy against resistant nematodes in lambs treated with different albendazole formulations.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2011 vol. 34 p. 557 - 564

CEBALLOS L; ELISSONDO, C; SANCHEZ BRUNI, S; DENEGRI, G; LANUSSE, C; ALVAREZ, L

Comparative performance of flubendazole and albendazole in cystic echinococcosis: ex vivo activity, plasma/cysts disposition and efficacy in infected mice.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2011 p. 5861 - 5867

DEVINE C; BRENNAN G; LANUSSE C; ALVAREZ L; TRUDGETT A,; HOEY E,; FAIRWEATHER I,

Inhibition of cytochrome P450-mediated metabolism enhances ex vivo susceptibility of Fasciola hepatica to triclabendazole

PARASITOLOGY; Lugar: United Kingdom; Año: 2010 vol. 22 p. 1 - 10

MORENO, L;; CEBALLOS L; LIFSCHITZ A; BISOLETTI, M; ALVAREZ L,; LANUSSE C

Combined subcutaneous administration of ivermectin and nitroxynil in sheep: Age/body weight related changes to the kinetic disposition of both compounds

RESEARCH IN VETERINARY SCIENCE; Año: 2010 vol. 88 p. 315 - 320

LIFSCHITZ, A; SUAREZ, V; SALLOVITZ, J.M; CRISTEL S,; IMPERIALE F; AHOUSSOU S; SCHIAVI C; LANUSSE, C

Cattle nematodes resistant to macrocyclic lactones: Comparative effects of P-glycoprotein modulation on the efficacy and disposition kinetics of ivermectin and moxidectin.

EXPERIMENTAL PARASITOLOGY; Año: 2010 vol. 125 p. 172 - 178

LIFSCHITZ, A; ENTROCASSO C,; ALVAREZ L; LLOBERAS, M; BALLENT M; MANAZZA J; VIRKEL, G; LANUSSE C

Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep.

VETERINARY PARASITOLOGY; Año: 2010 vol. 172 p. 291 - 298

CASTRO, S.; SANCHEZ BRUNI S; LANUSSE C; ALLEMANDI, D; PALMA S

Improved Albendazole Dissolution Rate in Pluronic 188 Solid Dispersions

AAPS PHARMSCITECH; Lugar: Virginia; Año: 2010 vol. 11 p. 1518 - 1525

BALLENT M; LIFSCHITZ A; VIRKEL G; MATE L; LANUSSE C

Pretreatment with the inducers rifampicin and phenobarbital alters ivermectin gastrointestinal disposition.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2010 vol. 33 p. 252 - 259

CEBALLOS L; MORENO L; ALVAREZ L; SHAW L; FAIRWEATHER I; LANUSSE C

Unchanged triclabendazole kinetics after co-administration with ivermectin and methimazole: failure of its therapeutic activity against triclabendazole-resistant liver flukes.

BMC VETERINARY RESEARCH; Lugar: London; Año: 2010 vol. 6 p. 8 - 12

DEVINE C; BRENNAN G; LANUSSE C; ALVAREZ, L; TRUDGETT A; HOEY E,; FAIRWEATHER I

Potentiation of triclabendazole sulphoxide-induced tegumental disruption by methimazole in a triclabendazole-resistant isolate of Fasciola hepatica.

PARASITOLOGY RESEARCH; Lugar: New York; Año: 2010 vol. 106 p. 1351 - 1363

DEVINE C; BRENNAN G; LANUSSE C; ALVAREZ L; TRUDGETT A; HOEY E,; FAIRWEATHER, I

Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole.

PARASITOLOGY RESEARCH; Lugar: New York; Año: 2010 vol. 107 p. 337 - 353

ALVAREZ, L; ENTROCASSO, C; LIFSCHITZ, A; MANAZZA, J; CEBALLOS, L; BORDA, B; LANUSSE, C

Albendazole failure to control resistant nematodes in lambs: Lack of effect of fasting-induced improvement on drug absorption

JOURNAL OF PARASITOLOGY; Año: 2010 vol. 96 p. 1204 - 1210

DEVINE C; BRENNAN G; LANUSSE C; ALVAREZ L; TRUDGETT A; HOEY E; FAIRWEATHER I

Piperonyl butoxide enhances triclabendazole action against triclabendazole-resistant Fasciola hepatica.

PARASITOLOGY; Año: 2010 vol. 138 p. 224 - 236

LANUSSE, C

Anthelmintic therapy in ruminant species: Understanding of the host-drug-parasite interaction

Anti-Infective Agents in Medicinal Chemistry; Lugar: New York; Año: 2010 vol. 9 p. 130 - 138

MATÉ L; VIRKEL, G.; LIFSCHITZ, A; SALLOVITS, J; BALLENT, M; LANUSSE, C

Phase 1 and phase 2 metabolic activities along the small intestine in adult male sheep.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: London; Año: 2010 vol. 33 p. 537 - 545

BALLENT M,; LIFSCHITZ, A.; VIRKEL G.; SALLOVITZ J; MATÉ L; LANUSSE C,

Gender-related differences on P-glycoprotein-mediated drug intestinal transport in rats.

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 2010 p. 619 - 626

CEBALLOS L; ELISSONDO C; SANCHEZ BRUNI, S; CONFALONIERI A; DENEGRI, G; ALVAREZ L; LANUSSE C

Chemoprophylactic activity of flubendazole in cystic echinococcosis

CHEMOTHERAPY; Lugar: Basel; Año: 2010 vol. 56 p. 386 - 392

LIFSCHITZ A; VIRKEL G; BALLENT M; SALLOVITS J; LANUSSE C

Combined use of ivermectin and triclabendazole in sheep: In vitro and in vivo characterisation of their pharmacological interaction

The Veterinary Journal; Lugar: London; Año: 2009 vol. 182 p. 261 - 268

GANDOLF A; LIFSCHITZ A; STANDLER C; WATSON B; GALVANEK L; BALLENT M; LANUSSE C

THE PHARMACOKINETICS OF ORALLY ADMINISTERED IVERMECTIN IN AFRICAN ELEPHANTS (LOXODONTA AFRICANA): IMPLICATIONS FOR PARASITE ELIMINATION

JOURNAL OF ZOO AND WILDLIFE MEDICINE; Lugar: Florida - USA; Año: 2009 vol. 40 p. 107 - 112

IMPERIALE F; FARIAS, C; SALLOVITS J; LIFSCHITZ A; LANUSSE C

Licking induced changes to the pattern of moxidectin milk elimination after topical treatment in dairy cows

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Indianapolis - United State; Año: 2009 vol. 32 p. 534 - 540

ALVAREZ L; MORENO G; MORENO L; CEBALLOS L; SHAW L; FAIRWEATHER I; LANUSSE C

Comparative assessment of albendazole and triclabendazole ovicidal activity on Fasciola hepatica eggs

VETERINARY PARASITOLOGY; Lugar: London; Año: 2009 vol. 164 p. 211 - 216

ELISSONDO M; CEBALLOS L; ALVAREZ L; SANCHEZ BRUNI S; LANUSSE C; DENEGRI, G

Flubendazole and ivermectin in vitro combination therapy produces a marked effect on Echinococcus granulosus protoscoleces and metacestodes.

PARASITOLOGY RESEARCH; Lugar: Germany; Año: 2009 vol. 105 p. 835 - 842

CAPECE B; VIRKEL G; LANUSSE C

Enantiomeric behaviour of albendazole and fenbendazole sulfoxides in domestic animals: Pharmacological implications

The Veterinary Journal; Año: 2009 vol. 181 p. 241 - 250

IMPERIALE F; FARIAS, C; PIS A,; SALLOVITS J; LIFSCHITZ A; LANUSSE C

Thermal stability of antiparasitic macrocyclic lactones milk residues during industrial processing

FOOD ADDITIVES AND CONTAMINANTS; Año: 2009 vol. 26 p. 57 - 62

CEBALLOS L; ELISSONDO C; SANCHEZ BRUNI S; DENEGRI G,; ALVAREZ L; LANUSSE C

Flubendazole in cystic echinococcosis therapy: Pharmaco-parasitological evaluation in mice

PARASITOLOGY INTERNATIONAL; Año: 2009 vol. 58 p. 354 - 358

SUAREZ, V; SALLOVITZ, J; LIFSCHITZ, A; LANUSSE C.

Effects of faecal residues of moxidectin and doramectin on the activity of arthropods in cattle dung

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY; Año: 2009 vol. 72 p. 1551 - 1578

SOLANA H; SCARCELLA S, , ; VIRKEL G; CERIANI C,; RODRIGUEZ J,; LANUSSE C

Albendazole enantiomeric metabolism and binding to cytosolic proteins in the liver fluke Fasciola hepatica

VETERINARY RESEARCH COMMUNICATIONS; Año: 2009 vol. 33 p. 163 - 173

VIRKEL, G; LIFSCHITZ A,; SALLOVITZ, J; BALLENT M; SCARCELLA S,; LANUSSE, C

Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: London; Año: 2009 vol. 32 p. 79 - 86

LANUSSE, C

Pharmacological challenges to achieve sustainable anthelmintic control in ruminants.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2009 vol. 32 p. 11 - 1363

DEVINE C; BRENNAN G; LANUSSE, C; ALVAREZ, L; TRUDGETT A; HOEY E; FAIRWEATHER I

Effect of the metabolic inhibitor, methimazole on the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica.

PARASITOLOGY; Año: 2009 vol. 136 p. 183 - 192

ALVAREZ L,; LIFSCHITZ A,; ENTROCASSO C,; MANAZZA J; MOTTIER L,; BORDA B,; VIRKEL G; LANUSSE C

Evaluation of the interaction between ivermectin and albendazole following their combined use in lambs.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2008 p. 230 - 239

CEBALLOS L,; ELISSONDO C,; MORENO L,; DOPCHIZ M,; SÁNCHEZ BRUNI S,; DENEGRI G,; ALVAREZ L,; LANUSSE C.

Albendazole treatment in cystic echinococcosis: pharmacokinetics and clinical efficacy of two different aqueous formulations

PARASITOLOGY RESEARCH; Año: 2008 p. 355 - 362

ENTROCASSO C,; ALVAREZ L, ,; MANAZZA J,; LIFSCHITZ A,; BORDA B,; VIRKEL G,; MOTTIER L,; LANUSSE C.

Clinical efficacy assessment of the albendazole-ivermectin combination in lambs parasitized with resistant nematodes.

VETERINARY PARASITOLOGY; Año: 2008

MORENO, L.;; ALVAREZ, L.; CEBALLOS, L; SANCHEZ BRUNI, S; LANUSSE, C.

Pattern of ivermectin (sheep) and doramectin (cattle) residues in muscular tissue from different anatomical locations.

FOOD ADDITIVES AND CONTAMINANTS; Año: 2008 p. 406 - 412

LIFSCHITZ A,; VIRKEL G.; BALLENT M,; SALLOVITS J,; LANUSSE C

Combined use of ivermectin and triclabendazole in sheep: In vitro and in vivo characterisation of their pharmacological interaction

THE VETERINARY JOURNAL; Lugar: Londres; Año: 2008

MATÉ L.; VIRKEL G; LIFSCHITZ A,; BALLENT M.; LANUSSE C

Hepatic and extra-hepatic metabolic pathways involved in flubendazole biotransformation in sheep

BIOCHEMICAL PHARMACOLOGY; Año: 2008 vol. 76 p. 773 - 783

LIFSCHITZ A,; NAVA S,; GUGLIELMONE A.,; IMPERIALE,F; FARIAS, C.; MANGOLD A,; LANUSSE, C.

Failure of ivermectin and eprinomectin to control Amblyomma parvum in goats: characterization of acaricidal activity and drug pharmacokinetic disposition

VETERINARY PARASITOLOGY; Año: 2008 vol. 156 p. 284 - 292

MOTTIER L,, ,; ALVAREZ L; FAIRWEATHER, I; LANUSSE C.

Resistance induced changes on triclabendazole transport in Fasciola hepatica: ivermectin reversal effect.

JOURNAL OF PARASITOLOGY; Año: 2007 vol. 92 p. 1355 - 1360

LIFSCHITZ A,; VIRKEL G,; BALLENT, M; SALLOVITZ J,; PIS A,; LANUSSE, C

Ivermectin (3.15%) long-acting formulations in cattle: absorption pattern and pharmacokinetic considerations

VETERINARY PARASITOLOGY; Año: 2007 p. 303 - 310

BALLENT M,; LIFSCHITZ A,; VIRKEL G,; SALLOVITZ J,; LANUSSE C.

Involvement of P-glycoprotein on ivermectin kinetic behaviour in sheep: itraconazole-mediated changes on gastrointestinal disposition.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2007 p. 242 - 248

ALVAREZ L.; MOTTIER L; LANUSSE C

Drug transfer into target helmint parasites.

TRENDS IN PARASITOLOGY; Año: 2007 p. 97 - 104

BRENNAN GP,; FAIRWEATHER I,; TRUDGETT A,; HOEY E,; MCCOY, M,; MCFERRAN N,; RYAN L,; LANUSSE C,; MOTTIER L,; ALVAREZ L, .; SOLANA H,; VIRKEL G,; BROPHY PM

Understanding triclabendazole resistance. Experimental Molecular Pathology,

EXPERIMENTAL MOLECULAR PATHOLOGY; Año: 2007 p. 104 - 109

ELISSONDO M, DOPCHIZ M, CEBALLOS L, ALVAREZ L, SANCHEZ BRUNI S, LANUSSE C, DENEGRI G.

In vitro effects of flubendazole on Echinococcus granulosus protoscoleces

PARASITOLOGY RESEARCH; Lugar: Berlin; Año: 2006 vol. 98 p. 317 - 323

VIRKEL G, LIFSCHITZ A, SALLOVITZ J, PIS A, LANUSSE C.

Assessment of the main metabolic pathways for the flukicidal compound triclabendazole in sheep

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Londres; Año: 2006 vol. 29 p. 213 - 223

LIFSCHITZ, A..; BALLENT, M.; VIRKEL, G., SALLOVITZ, J; LANUSSE, C.

Sex-related differences in the gastrointestinal disposition of ivermectin in the rat: P-glycoprotein involvement and itraconazole modulation

JOURNAL OF PHARMACY AND PHARMACOLOGY; Lugar: Londres; Año: 2006 vol. 58 p. 1055 - 1062

IMPERIALE, F; PIS, A; SALLOVITZ, J; LISFCHITZ, A; BUSETTI, M; SUÁREZ V; LANUSSE C

Pattern of eprinomectin milk excretion in dairy sheep unaffected by lactation stage: comparative residual profiles in dairy products

JOURNAL OF FOOD PROTECTION; Lugar: Iowa; Año: 2006 vol. 69 p. 2424 - 2429

MOTTIER L, ALVAREZ L, CEBALLOS L, LANUSSE C

Drug transport mechanisms in helminth parasites: Passive diffusion of benzimidazole anthelmintics

EXPERIMENTAL PARASITOLOGY; Lugar: Amsterdam; Año: 2006 vol. 113 p. 49 - 57

BALLENT M, LIFSCHITZ A, VIRKEL G, SALLOVITZ J, LANUSSE C

Modulation of the P-glycoprotein-mediated intestinal secretion of ivermectin: in vitro and in vivo assessments

DRUG METABOLISM AND DISPOSITION; Año: 2006 vol. 34 p. 457 - 462

LIFSCHITZ, A., VIRKEL, G., BALLENT, M., SALLOVITZ, J., LANUSSE, C.

Moxidectin and ivermectin metabolic stability in sheep ruminal and abomasal contents

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2005 vol. 28 p. 411 - 418

SALLOVITZ, J., LIFSCHITZ, A., VIRKEL, G., LANUSSE, C.

Doramectin concentration profiles in the gastrointestinal tract of topically-treated calves: influence of animal licking restriction

VETERINARY PARASITOLOGY; Lugar: Amsterdam; Año: 2005 vol. 133 p. 61 - 70

MORENO, L., IMPERIALE F., ALVAREZ, L., LANUSSE C.

Comparison of milk residue profiles after oral and subcutaneous administration of benzimidazole anthelmintics to dairy cows.

ANALYTICA CHIMICA ACTA; Lugar: Amsterdam; Año: 2005 vol. 536 p. 91 - 99

ALVAREZ, L. SOLANA H., MOTTIER L., VIRKEL, G.,., FAIRWEATHER, I., LANUSSE, C.

Altered drug influx/efflux and enhanced metabolic activity in triclabendazole-resistant liver flukes.

PARASITOLOGY; Lugar: Cambridge; Año: 2005 vol. 131 p. 501 - 510

SÁNCHEZ BRUNI, S., SAUMELL, C., MORENO, L., ALVAREZ, L., FUSÉ, L., FIEL, C.; MCKELLAR, Q., LANUSSE, C

Changes to oxfendazole chiral kinetics and anthelmintic efficacy induced by piperonyl butoxide in horses.

EQUINE VETERINARY JOURNAL; Lugar: London; Año: 2005 vol. 37 p. 257 - 262

BALLENT, M; LIFSCHITZ, A..; VIRKEL, G.; LANUSSE C

Caracterización del rol de los transportadores celulares: implicancias terapéuticas en medicina veterinaria

ANALECTA VETERINARIA; Lugar: La Plata; Año: 2005 vol. 25 p. 36 - 47

VIRKEL, G.; LIFSCHITZ, A.; SALLOVITZ, J.; INZA, G.; LANUSSE, C..

Effect of the ionophore monensin on the ruminal biotransformation of benzimidazole anthelmintics

The Veterinary Journal; Año: 2004 vol. 167 p. 265 - 272

LIFSCHITZ, A., SALLOVITZ, J., IMPERIALE, F., PIS, A., LANUSSE, C.

Pharmacokinetic evaluation of four ivermectin generic formulations in calves.

VETERINARY PARASITOLOGY; Año: 2004 vol. 119 p. 247 - 257

MOLENTO, M. LIFSCHITZ, A., SALLOVITZ, J., LANUSSE, C.., PRICHARD, R

Influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep.

PARASITOLOGY RESEARCH; Año: 2004 vol. 92 p. 121 - 127

ALVAREZ, L.; MOTTIER, L.; LANUSSE, C

Comparative assessment of the access of albendazole, fenbendazole and triclabendazole to Fasciola hepatica: effect of bile in the incubation medium.

. Parasitololgy; Lugar: United Kingdom; Año: 2004 vol. 128 p. 73 - 81

LIFSCHITZ, A., VIRKEL, G., SALLOVITZ, J., IMPERIALE, F., LANUSSE, C.

Loperamide modifies the tissue disposition kinetics of ivermectin in rats.

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 2004 vol. 56 p. 61 - 67

IMPERIALE, F., LIFSCHITZ, A., SALLOVITZ, J., LANUSSE, C

Comparative depletion of ivermectin and moxidectin milk residues in dairy sheep after subcuatneous and oral adminstration.

Journal of Dairy Research; Lugar: United Kingdom; Año: 2004 vol. 71 p. 427 - 433

MOTTIER, L.; MORENO L.; ALVAREZ, L.; VIRKEL, G.; LANUSSE, C

Measurement of triclabendazole and its metabolites in liver flukes: method development and full validation

. Journal of Pharmaceutical and Biomedical Analysis; Año: 2004 vol. 35 p. 991 - 999

MORENO L., ECHEVARRÍA F., MUÑOZ, F., ALVAREZ; L., SANCHEZ, S. ; LANUSSE C.

Dose-dependent activity of albendazole against benzimidazole-resistant nematodes in sheep: relationship between pharmacokinetics and efficacy.

EXPERIMENTAL PARASITOLOGY; Año: 2004 vol. 106 p. 150 - 157

IMPERIALE F., BUSETTI M., SUÁREZ V, LANUSSE C.

Milk excretion of ivermectin and moxidectin in dairy sheep: assessment of drug residues during cheese elaboration and ripening period

Journal of Agriculture and Food Chemistry; Año: 2004 vol. 52 p. 6205 - 6211

MORENO L., ALVAREZ L., MOTTIER, L:, VIRKEL, G., SANCHEZ S., LANUSSE C.

Integrated pharmacological assessment of flubendazole potential for use in sheep: disposition kinetics, liver metabolism and parasite diffusion ability

Journal of Veterinary Pharmacology and Therapeutics.; Año: 2004 vol. 27 p. 299 - 308

POMARICO J, DI ROCCO O, ALVAREZ L., MOTTIER L., LANUSSE C., SAUMELL C, TRIVI M.

Speckle interferometry applied to pharmacodynamic studies: evaluation of parasite motility

European Biophysics Journal; Año: 2004 vol. 33 p. 694 - 699

VIRKEL, G.; LIFSCHITZ, A.; SALLOVITZ, J., PIS A.; LANUSSE, C

Comparative hepatic and extrahepatic enantioselective sulfoxidation of albendazole and fenbendazole in sheep and cattle.

. Drug Metabolism and Disposition; Año: 2004 vol. 32 p. 536 - 544

MOTTIER L., VIRKEL, G., SOLANA H., ALVAREZ L., LANUSSE C.

Triclabendazole biotransformation and comparative diffusion of the parent drug and its oxidised metabolites into Fasciola hepatica.

XENOBIOTICA; Lugar: United Kingdom; Año: 2004 vol. 34 p. 1043 - 1057

VIRKEL, G.; LIFSCHITZ, A.; PIS, A.; PRIETO, J., MERINO, A., LANUSSE, C.

Effect of amphiphilic surfactant agents on the gastrointestinal absorption of albendazole in cattle

Biopharmaceutics and Drug Disposition; Lugar: London; Año: 2003 vol. 24 p. 95 - 103

SUAREZ, V.; LIFSCHITZ, A.; SALLOVITZ, J.; LANUSSE, C

Effects of ivermectin and doramectin faecal residues on the invertebrate colonization of cattle dung

JOURNAL OF APPLIED ENTOMOLOGY; Lugar: Berlin; Año: 2003 vol. 127 p. 481 - 488

MOTTIER, L.; ALVAREZ, L.; PIS, A.; LANUSSE, C.

). Transtegumental difussion of benzimidazole anthelmintics into Moniezia benedeni: correlation with their octanol-water partition coefficients.

EXPERIMENTAL PARASITOLOGY; Año: 2003 vol. 103 p. 1 - 7

LANUSSE, C

Comparative pharmacokinetics of anthelmintic drugs in ruminants. -Updated integration of available knowledge

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Lugar: Lisboa; Año: 2003 vol. 26 p. 42 - 47

TERUEL, M., SOLANA, H., FELIPE, A., SALLOVITZ, J., LANUSSE, C

Placental and fetal toxicity of albendazole sulphoxide in Wistar rats.

VETERINARY AND HUMAN TOXICOLOGY; Año: 2003 vol. 45 p. 131 - 136

MOTTIER, L.; ALVAREZ, L.; LANUSSE, C

Quantitative chromatographic determination of several benzimidazole anthelmintic molecules in parasite material.

Journal of Chromatography B; Año: 2003 vol. 798 p. 117 - 125

IMPERIALE, F., MOTTIER, L., SALLOVITZ, J., LIFSCHITZ, A., LANUSSE, C

Disposition of doramectin milk residues in lactating dairy sheep.

Journal of Agriculture and Food Chemistry,; Año: 2003 vol. 51 p. 3185 - 3190

SALLOVITZ, J., LIFSCHITZ, A., VIRKEL, G., LANUSSE, C.

A detailed assessment of the pattern of moxidectin tissue distribution after pour-on treatment in calves.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2003 vol. 26 p. 397 - 404