Pharmacological challenges to achieve sustainable anthelmintic control in ruminants.

LANUSSE, C

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

WILEY-BLACKWELL PUBLISHING, INC

Año: 2009 vol. 32 p. 11 - 1363

0140-7783

Helminth parasites of domestic ruminants produce the greatest infectious disease problem in grazing livestock systems worldwide. Despite promising research results, non-chemical parasite control strategies are not yet available for routine commercial use. Thus, helminths control in livestock animals still relies on the use of antiparasitic drugs, which comprise the largest sector of the animal pharmaceutical industry, where the cattle market accounts for the greatest sales [1]. The integration of available information on the host-parasite-environment relationship, with a more complete understanding of the pharmacological properties of existing antiparasitic drugs has contributed to more efficient parasite control. However, due to the magnitude of the investment in drug medications to control helminths in ruminants, it is highly important to generate scientific information on how to improve the use of available molecules to maximize their efficacy, and particularly, to avoid/delay the development of parasite resistance.