Gaining Insights Into the Pharmacology of Anthelmintics Using Haemonchus contortus as a Model Nematode

LANUSSE, C ; ALVAREZ L.; LIFSCHITZ A.

ADVANCES IN PARASITOLOGY.

ELSEVIER ACADEMIC PRESS INC

Lugar: Burlington, MA, Estados Unidos; Año: 2016 vol. 93 p. 465 - 518

0065-308X

Progress made in understanding pharmacokinetic behaviour and pharmacodynamic mechanisms of drug action/resistance has allowed deep insights into the pharmacology of the main chemical classes, including some of the few recently discovered anthelmintics. The integration of pharmaco-parasitological research approaches has contributed considerably to the optimization of drug activity, which is relevant to preserve existing and novel active compounds for parasite control in livestock. A remarkable ...