INVESTIGADORES
VALDEZ Laura Beatriz
artículos
PEREZ A; MUKDSI J; VALDEZ LB; RUKAVINA MIKUSIC IA; DÍAZ DE BARBOZA G; TOLOSA DE TALAMONI N; RIVOIRA M
Naringin prevents diabetic nephropathy in rats through blockage of oxidative stress and attenuation of the mitochondrial dysfunction
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY; Lugar: Ottawa; Año: 2023
RUKAVINA-MIKUSIC, IVANA A.; REY, MICAELA; ADÁN AREÁN, JUAN S.; VANASCO, VIRGINIA; ALVAREZ, SILVIA; VALDEZ, LAURA B.
Mitochondrial H2O2 metabolism as central event of heart complex I syndrome in early diabetes
FREE RADICAL BIOLOGY AND MEDICINE; Año: 2023 vol. 201 p. 66 - 75
RUKAVINA MIKUSIC IA; REY M; TRIPODI V; VALDEZ LB
Complejo I, H2O2 y NO mitocondriales como señales prodrómicas de la disfunción cardíaca en diabetes tipo 1
Revista Argentina de Cardiologia; Lugar: Buenos Aires; Año: 2021 vol. 89 p. 92 - 97
RUKAVINA-MIKUSIC, IVANA A.; REY, MICAELA; MARTINEFSKI, MANUELA; TRIPODI, VALERIA; VALDEZ, LAURA B.
Temporal evolution of cardiac mitochondrial dysfunction in a type 1 diabetes model. Mitochondrial complex I impairment, and H2O2 and NO productions as early subcellular events
FREE RADICAL BIOLOGY AND MEDICINE; Año: 2021 vol. 162 p. 129 - 140
POSTMA, GABRIELA CINTIA; NICASTRO, CAROLINA NATALIA; VALDEZ, LAURA BEATRIZ; RUKAVINA MIKUSIC, IVANA AGUSTINA; GRECCO, ANDRÉS; MINATEL, LEONARDO
Decrease lysyl oxidase activity in hearts of copper-deficient bovines
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY; Año: 2021 vol. 65
RUKAVINA MIKUSIC IA; REY M; TRIPODI, V; VALDEZ LB
Complejo I, H2O2 y NO mitocondriales como señales prodrómicas de la disfunción cardíaca en diabetes tipo 1
Revista Argentina de Cardiología; Lugar: Capital Federal; Año: 2021 vol. 89 p. 92 - 97
IGLESIAS DE; BOMBICINO SS; BOVERIS A; VALDEZ LB
(+)-Catechin inhibits heart mitochondrial complex i and nitric oxide synthase: Functional consequences on membrane potential and hydrogen peroxide production
Food and Function; Lugar: Cambridge; Año: 2019 vol. 10 p. 2528 - 2537
IGLESIAS, DARÍO E.; BOMBICINO, SILVINA S.; BOVERIS, ALBERTO; VALDEZ, LAURA B.
(+)-Catechin inhibits heart mitochondrial complex I and nitric oxide synthase: functional consequences on membrane potential and hydrogen peroxide production
Food & Function; Lugar: Cambridge; Año: 2019 vol. 10 p. 2528 - 2537
VALDEZ, LAURA B.; ZAOBORNYJ, TAMARA; BANDEZ, MANUEL J.; LÓPEZ-CEPERO, JOSÉ MARÍA; BOVERIS, ALBERTO; NAVARRO, ANA
Complex I syndrome in striatum and frontal cortex in a rat model of Parkinson disease
FREE RADICAL BIOLOGY AND MEDICINE; Año: 2019 vol. 135 p. 274 - 282
OLIVARES, ROBERTO WALTER ISRAEL; POSTMA, GABRIELA CINTIA; SCHAPIRA, ANDREA; IGLESIAS, DARIO EZEQUIEL; VALDEZ, LAURA BEATRIZ; BREININGER, ELIZABETH; GAZZANEO, PABLO DANIEL; MINATEL, LEONARDO
Biochemical and Morphological Alterations in Hearts of Copper-Deficient Bovines
BIOLOGICAL TRACE ELEMENT RESEARCH; Año: 2018 vol. 189 p. 447 - 455
VALDEZ LB; BOMBICINO SS; IGLESIAS DE; RUKAVINA-MIKUSIC IA; BOVERIS A
Mitochondrial peroxynitrite generation is mainly driven by superoxide steady-state concentration rather than by nitric oxide steady-state concentration.
International Journal of Molecular Biology: Open Access; Lugar: Edmond, Oklahoma; Año: 2018 vol. 3 p. 58 - 63
OGONOWSKI N; VALDEZ LB; ZAOBORNYJ T,; PUCHULU MB; BALASZCZUK AM ; FELLET AL
Thyroid hormones and heart mitochondrial nitric oxide under hypovolemia
Endocrinol Metab Int J; Lugar: Edmond, Oklahoma; Año: 2018 vol. 6 p. 343 - 347
BOMBICINO, SILVINA S.; IGLESIAS, DARÍO E.; RUKAVINA-MIKUSIC, IVANA A.; BUCHHOLZ, BRUNO; GELPI, RICARDO J.; BOVERIS, ALBERTO; VALDEZ, LAURA B.
Hydrogen peroxide, nitric oxide and ATP are molecules involved in cardiac mitochondrial biogenesis in Diabetes
FREE RADICAL BIOLOGY AND MEDICINE; Año: 2017 vol. 112 p. 267 - 276
DONATO, MARTÍN; BUCHHOLZ, BRUNO; MORALES, CELINA; VALDEZ, LAURA; ZAOBORNYJ, TAMARA; BARATTA, SERGIO; PAEZ, DIAMELA T.; MATOSO, MIRIAN; VACCARINO, GUILLERMO; CHEJTMAN, DEMIAN; AGÜERO, OSCAR; TELAYNA, JUAN; NAVIA, JOSÉ; HITA, ALEJANDRO; BOVERIS, ALBERTO; GELPI, RICARDO J.
Loss of dystrophin is associated with increased myocardial stiffness in a model of left ventricular hypertrophy
MOLECULAR AND CELLULAR BIOCHEMISTRY; Año: 2017 vol. 432 p. 169 - 178
POSTMA GC; MINATEL L; OLIVARES RWI; SCHAPIRA A; VALDEZ LB; DALLORSO ME
Superoxide dismutase activity, hydrogen peroxide steady-state concentration, bactericidal and phagocytic activities against Moraxella bovis, in neutrophils isolated from copper deficient bovines
BIOLOGICAL TRACE ELEMENT RESEARCH; Lugar: New York; Año: 2016 vol. 171 p. 94 - 100
ZAOBORNYJ T; IGLESIAS DE,; BOMBICINO SS; BOVERIS A.; VALDEZ LB
Nitric oxide metabolism in heart mitocondria
BIOCELL; Lugar: Mendoza; Año: 2016 vol. 40 p. 55 - 58
BOMBICINO SS; IGLESIAS DE; RUKAVINA MIKUSIC IA; BOVERIS A; VALDEZ LB
Mitochondrial dysfunction in the diabetic heart
BIOCELL; Lugar: Mendoza; Año: 2016 vol. 40 p. 7 - 10
BOMBICINO SS; IGLESIAS DE; RUKAVINA MIKUSIC IA; D?ANNUNZIO V; GELPI RJ; BOVERIS A; VALDEZ LB
Diabetes impairs heart mitochondrial function without changes in resting cardiac performance
INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELLULAR BIOLOGY; Lugar: Amsterdam; Año: 2016 vol. 81 p. 335 - 345
IGLESIAS DE; BOMBICINO SS; BOVERIS A; VALDEZ LB
Superoxide and hydrogen peroxide productions by NO-inhibited complex III
BIOCELL; Lugar: Mendoza; Año: 2016 vol. 40 p. 27 - 30
PEREZ V; DANNUNZIO V; VALDEZ LB; ZAOBORNYJ T; BOMBICINO S; MAZO T; LONGO CARBAJOSA N; GIRONACCI M; BOVERIS A; SADOSHIMA J; GELPI RJ
Thioredoxin-1 attenuates ventricular and mitochondrial post-ischemic dysfunction in the stunned myocardium of transgenic mice
ANTIOXIDANTS & REDOX SIGNALING; Lugar: New York; Año: 2016 vol. 25 p. 78 - 88
BOMBICINO SS; IGLESIAS DE; ZAOBORNYJ T; BOVERIS A; VALDEZ LB
Mitochondrial nitric oxide production supported by reverse electron transfer
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS; Lugar: Amsterdam; Año: 2016 vol. 607 p. 8 - 19
MAZO T; PÉREZ V; GÓMEZ A; LLAMOSAS C; VALDEZ LB; ZAOBORNYJ T; NICOLOSI L; RUBIO MC; DANNUNZIO V; GELPI RJ
Papel de la tiorredoxina-1 en el atontamiento cardíaco en ratones transgénicos
Rev Arg Cardiol; Lugar: Buenos Aires; Año: 2015 vol. 83 p. 394 - 399
IGLESIAS DE; BOMBICINO SS; VALDEZ LB; BOVERIS A
Nitric oxide interacts with mitochondrial complex III producing antimycin-like effects
FREE RADICAL BIOLOGY AND MEDICINE; Año: 2015 vol. 89 p. 602 - 613
MAZO, TAMARA; PÉREZ, VIRGINIA; GÓMEZ, ANABELLA; LLAMOSAS, CLARA; VÁLDEZ, LAURA; ZAOBORNYJ, TAMARA; NICOLOSI, LILIANA; RUBIO, MARÍA; D´ANNUNZIO, VERÓNICA; GELPI, RICARDO J.
Papel de la tiorredoxina-1 en el atontamiento cardíaco en ratones transgénicos
Revista Argentina de Cardiología; Lugar: Buenos Aires; Año: 2015 vol. 83 p. 394 - 399
D'ANNUNZIO V; DONATO M; FELLET A; BUCHHOLZ B; ARCIUCH VG; CARRERAS MC; VALDEZ LB; ZAOBORNYJ T; MORALES C; BOVERIS A; PODEROSO JJ; BALASZCZUK AM; GELPI RJ
Diastolic function during hemorrhagic shock in rabbits
MOLECULAR AND CELLULAR BIOCHEMISTRY; Lugar: New York; Año: 2012 vol. 359 p. 169 - 176
VANASCO V; MAGNANI ND; CIMOLAI MC; VALDEZ LB; EVELSON P; BOVERIS A; ALVAREZ S
Endotoxemia impairs heart mitochondrial function by decreasing electron transfer, ATP synthesis and ATP content without affecting membrane potential.
JOURNAL OF BIOENERGETICS AND BIOMEMBRANES; Lugar: New York; Año: 2012 vol. 44 p. 243 - 252
RODRIGUEZ PC; VALDEZ LB; ZAOBORNYJ T; BOVERIS A; BECONI MT
Nitric oxide and superoxide anion production during heparin induced capacitation in criopreserved bovine spermatozoa
REPRODUCTION IN DOMESTIC ANIMALS (1990); Año: 2011 vol. 46 p. 74 - 81
VALDEZ LB; ZAOBORNYJ T; BOMBICINO SS; IGLESIAS DE; BOVERIS A; DONATO M; D'ANNUNZIO V; BUCHHOLZ B; GELPI R
COMPLEX I SYNDROME IN MYOCARDIAL STUNNING AND THE EFFECT OF ADENOSINE
FREE RADICAL BIOLOGY AND MEDICINE; Año: 2011 vol. 51 p. 1203 - 1212
DONATO M; D'ANNUNZIO V; BUCHHOLZ B; MIKSZTOWICZ V; CARRIÓN CL,; VALDEZ LB; ZAOBORNYJ T; SCHREIER L; WIKINSKI R; BOVERIS A; BERG G; GELPI RJ
Role of matrix metalloproteinase-2 in the cardioprotective effect of ischaemic postconditioning
EXPERIMENTAL PHYSIOLOGY.; Año: 2010 vol. 95 p. 274 - 281
ARRECHE ND; VALDEZ LB; ZAOBORNYJ T; BARATTO B; VATRELA M; MARTINEZ C; BOVERIS A; BALASZCZUK AM; FELLET AL
Shock hemorrágico: óxido nítrico en ratas anestesiadas y no anestesiadas
Revista Argentina de Cardiología; Lugar: Buenos Aires, Argentina; Año: 2009 vol. 77 p. 181 - 186
ZAOBORNYJ T; VALDEZ LB; IGLESIAS DE; GASCO M; GONZALES G; BOVERIS A
Mitochondrial nitric oxide metabolism during rat heart adaptation to high altitude: effect of sildenafil, L-NAME and L-arginine treatments
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY; Lugar: Bethesda MD; Año: 2009 vol. 296 p. 1741 - 1747
ZAOBORNYJ T; GONZALES GF; VALDEZ LB
Mitochondrial contribution to the molecular mechanism of heart acclimatization to chronic hypoxia: role of nitric oxide
Frontiers in Bioscience; Año: 2007 vol. 12 p. 1247 - 1259
VALDEZ LB; BOVERIS A
Mitochondrial nitric oxide synthase, a voltage-dependent enzyme, is responsible for nitric oxide diffusion to cytosol
Frontiers in Bioscience; Año: 2007 vol. 12 p. 1210 - 1219
VALDEZ LB; ZAOBORNYJ T; BOVERIS A
Mitochondrial metabolic states and membrane potential modulate mtNOS activity
Biochim Biophys Acta; Año: 2006 vol. 1757 p. 166 - 172
BOVERIS A; VALDEZ LB; ZAOBORNYJ T; BUSTAMANTE J
Mitochondrial metabolic states regulate nitric oxide and hydrogen peroxide diffusion to the cytosol
Biochim Biophys Acta; Año: 2006 vol. 1757 p. 535 - 542
GONZALES GF; CHUNG A; MIRANDA S; VALDEZ LB; ZAOBORNYJ T; BOVERIS A
Heart mitochondrial nitric oxide synthase is upregulated in male rats exposed to high altitude (4,340 m)
Am J Physiol Heart Circ Physiol; Lugar: Bethesda, Maryland, USA; Año: 2005 vol. 288 p. 2568 - 2573
VALDEZ LB; ZAOBORNYJ T; BOVERIS A
Functional activity of mitochondrial nitric oxide synthase
METHODS IN ENZYMOLOGY.; Lugar: Burlington, MA, Estados Unidos; Año: 2005 vol. 396 p. 444 - 455
VALDEZ LB; ZAOBORNYJ T; BOVERIS A
Functional activity of mitochondrial nitric oxide synthase
Methods Enzymol; Lugar: San Diego, California, USA; Año: 2005 vol. 396 p. 444 - 455
ZAOBORNYJ T; VALDEZ LB; BOVERIS A
Comments on Point:Counterpoint Positive effects of intermittent hypoxia (live high:train low) on exercise performance are/are not mediated primarily by augmented red cell volume
J Appl Physiol; Lugar: Bethesda, Maryland, USA; Año: 2005 vol. 99 p. 2453 - 2454
ZAOBORNYJ T; VALDEZ LB; LA PADULA P; COSTA LE; BOVERIS A
Effect of sustained hypobaric hypoxia during maturation and aging on rat myocardium. II. mtNOS activity
J Appl Physiol; Lugar: Bethesda, Maryland, USA; Año: 2005 vol. 98 p. 2370 - 2375
VALDEZ LB; ZAOBORNYJ T; ALVAREZ S; BUSTAMANTE J; COSTA LE; BOVERIS A
Heart mitochondrial nitric oxide synthase. Effects of hypoxia and aging.
Mol Aspects Med; Año: 2004 vol. 25 p. 49 - 59
VALDEZ LB; ALVAREZ S; ZAOBORNYJ T; BOVERIS A
Polyphenols and red wine as antioxidants against peroxynitrite and other oxidants
Biol Res; Año: 2004 vol. 37 p. 279 - 286
BOVERIS A; VALDEZ LB; ALVAREZ S; ZAOBORNYJ T; BOVERIS AD; NAVARRO A
Kidney mitochondrial nitric oxide synthase
Antioxid Redox Signal; Año: 2003 vol. 5 p. 265 - 271
ALVAREZ S; VALDEZ LB; LORES ARNAIZ S; ZAOBORNYJ T; BOVERIS A
Oxygen dependence of mitochondrial nitric oxide synthase activity
Biochem Biophys Res Commun; Año: 2003 vol. 305 p. 771 - 775
VALDEZ LB; ACTIS GORETTA L; BOVERIS A
Polyphenols in red wine prevents NADH oxidation induced by peroxynitrite
Ann N Y Acad Sci; Año: 2002 vol. 957 p. 274 - 278
BOVERIS A; VALDEZ LB; ALVAREZ S
Inhibition by wine polyphenols of peroxynitrite initiated chemiluminescence and NADH oxidation
Ann N Y Acad Sci; Año: 2002 vol. 957 p. 90 - 102
BOVERIS A; LORES ARNAIZ S; BUSTAMANTE J; ALVAREZ S; VALDEZ LB; BOVERIS AD; NAVARRO A
Pharmacological regulation of mitochondrial nitric oxide synthase.
Methods Enzymol; Año: 2002 vol. 359 p. 328 - 339
BOVERIS A; ALVAREZ S; BUSTAMANTE J; VALDEZ LB
Measurement of superoxide radical and hydrogen peroxide production in isolated cells and subcellular organelles
METHODS IN ENZYMOLOGY.; Lugar: Burlington, MA, Estados Unidos; Año: 2002 vol. 349 p. 280 - 287
BOVERIS A; LORES ARNAIZ S; BUSTAMANTE J; ALVAREZ S; VALDEZ LB; BOVERIS AD; NAVARRO A
Pharmacological regulation of mitochondrial nitric oxide synthase.
Methods Enzymol; Año: 2002 vol. 359 p. 328 - 339
BOVERIS A; ALVAREZ S; BUSTAMANTE J; VALDEZ LB
Measurement of superoxide radical and hydrogen peroxide production in isolated cells and subcellular organelles
Methods Enzymol; Año: 2002 vol. 349 p. 280 - 287
VALDEZ LB; BOVERIS A
Nitric oxide and superoxide radical production by human mononuclear leukocytes.
Antioxid Redox Signal; Año: 2001 vol. 3 p. 505 - 513
VALDEZ LB; LORES ARNAIZ S; BUSTAMANTE J; ALVAREZ S; COSTA LE; BOVERIS A
Free radical chemistry in biological systems
Biol Res; Año: 2000 vol. 33 p. 65 - 70
VALDEZ LB; ALVAREZ S; LORES ARNAIZ S; SCHOPFER F; CARRERAS MC; PODEROSO JJ; BOVERIS A
Reactions of peroxynitrite in the mitochondrial matrix
FREE RADICAL BIOLOGY AND MEDICINE; Lugar: Amsterdam; Año: 2000 vol. 29 p. 349 - 35629