Superoxide dismutase activity, hydrogen peroxide steady-state concentration, bactericidal and phagocytic activities against Moraxella bovis, in neutrophils isolated from copper deficient bovines

POSTMA GC; MINATEL L; OLIVARES RWI; SCHAPIRA A; VALDEZ LB; DALLORSO ME

BIOLOGICAL TRACE ELEMENT RESEARCH

Springer

Lugar: New York; Año: 2016 vol. 171 p. 94 - 100

0163-4984

Copper (Cu) deficiency increases occurrence of certain infectious diseases in animals, including infectious keratoconjunctivitis in bovines, a bacterial ocular inflammation caused by Moraxella bovis. Neutrophil leucocytes constitute the first phagocytic cells to arrive at infection sites for bacterial neutralization. The objective of this work was to evaluate whether the functionality of neutrophils against M. bovis are impaired in experimentally induced Cu deficiency in bovines using high molybdenum and sulphur levels in the diet. The Cu tissue values and the periocular achromotrichia observed in +Mo animals showed that the clinic phase of Cu.