Modulation lntestinal Epithelial of Toll-like Receptor 4-Mediated lnnate lmmunity in Bovine Cells by Lactic Acid Bacteria lsolated from Feedlot Cattle

VIGNOLO, GRACIELA, .; MANSILLA, FLAVIA I.; TAKAGI, MICHIHIRO; GARCIA-CASTILLO, VALERIA ; ASO, HISASHI ; NADER, MARIA ELENA ; KITAZAWA, HARUKI ; VILLENA, JULIO

Praga

Congreso; 13th. International Scientific Conference. Probiotics, Prebiotics, Gut Microbiota and Health; 2019

IPC

Lactobacillus (L.) acidophilus CRL2074, L. mucosae CRL2069, L. fermentum CR12085, and L. rhamnosus CRL20B4 isolated from feedlot cattle environment, were previously selected by their beneficial-probiotic characteristics including their ability toinhibit gastrointestinal pathogen´s growth. In this work, we aimed to go further in the evaluation of their ability to differently modulate the innate immune response triggered by Toll-like receptor (TLR)-4 activation in bovine intestinal epithellal cells (BIE cells).