INVESTIGADORES
GRAMAJO Hugo Cesar
artículos
BERCOVICH, BÁRBARA A.; VILLAFAÑE, DAVID L.; BIANCHI, JULIETA S.; TADDIA, CAMILA; GRAMAJO, HUGO; AMALIA CHIESA, MARÍA; RODRÍGUEZ, EDUARDO
Streptomyces eurocidicus promotes soybean growth and protects it from fungal infections
BIOLOGICAL CONTROL; Año: 2022 vol. 165
BRACALENTE, FERNANDO; SABATINI, MARTÍN; ARABOLAZA, ANA; GRAMAJO, HUGO
Escherichia coli coculture for de novo production of esters derived of methyl-branched alcohols and multi-methyl branched fatty acids
MICROBIAL CELL FACTORIES; Año: 2022 vol. 21
THEATER A; CANO PRIETO; BARTOLINI MARCO; ARABOLAZA A,; GRAMAJO, H; GROSS, H; PHILLIPE J
The Surfactin-Like Lipopeptides From Bacillus spp.: Natural Biodiversity and Synthetic Biology for a Broader Application Range
Frontiers in Bioengineering and biotechnology; Año: 2021
LANFRANCONI, MARIANA P.; ARABOLAZA, ANA; GRAMAJO, HUGO; ALVAREZ, HÉCTOR M.
Insights into the evolutionary history of the virulent factor HBHA of Mycobacterium tuberculosis
ARCHIVES OF MICROBIOLOGY; Año: 2021 vol. 203 p. 2171 - 2182
TUTTOBENE, M.R.; PÉREZ, J.F.; PAVESI, E.S.; MORA, B. PEREZ; BIANCOTTI, D.; CRIBB, P.; ALTILIO, M.; MÜLLER, G.L.; GRAMAJO, H.; TAMAGNO, G.; RAMÍREZ, M.S.; DIACOVICH, L.; MUSSI, M.A.
Light modulates important pathogenic determinants and virulence in ESKAPE pathogens acinetobacter baumannii, pseudomonas aeruginosa, and staphylococcus aureus
JOURNAL OF BACTERIOLOGY; Año: 2021 vol. 203
CROTTA ASIS, AGOSTINA; SAVORETTI, FRANCO; CABRUJA, MATÍAS; GRAMAJO, HUGO; GAGO, GABRIELA
Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria
Scientific Reports; Año: 2021 vol. 11
JULIA ROULET; GALVAN V; LARA J; SALAZAR M; CHOLICH J; GRAMAJO H; ARABOLAZA A
Modification of PapA5 acyltransferase substrate selectivity for optimization of short-chain alcohol-derived multimethyl-branched ester production in Escherichia coli
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY; Lugar: Berlin; Año: 2020
LARA, JULIA; DIACOVICH, LAUTARO; TRAJTENBERG, FELIPE; LARRIEUX, NICOLE; MALCHIODI, EMILIO L.; FERNÁNDEZ, MARISA M.; GAGO, GABRIELA; GRAMAJO, HUGO; BUSCHIAZZO, ALEJANDRO
Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine
NATURE COMMUNICATIONS; Año: 2020 vol. 11
MONDINO, SONIA; VÁZQUEZ, CRISTINA L.; CABRUJA, MATÍAS; SALA, CLAUDIA; CAZENAVE-GASSIOT, AMAURY; BLANCO, FEDERICO C.; WENK, MARKUS R.; BIGI, FABIANA; COLE, STEWART T.; GRAMAJO, HUGO; GAGO, GABRIELA
FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence of Mycobacterium tuberculosis
Frontiers in Microbiology; Año: 2020 vol. 11
LIVIERI, ANDREA L.; NAVONE, LAURA; MARCELLIN, ESTEBAN; GRAMAJO, HUGO; RODRIGUEZ, EDUARDO
A novel multidomain acyl-CoA carboxylase in Saccharopolyspora erythraea provides malonyl-CoA for de novo fatty acid biosynthesis
Scientific Reports; Año: 2019 vol. 9
ROULET J, TATON A, GOLDEN JW, ARABOLAZA A, BURKART MD, GRAMAJO H; HUGO GRAMAJO
Development of a cyanobacterial heterologous polyketide production platform.
METABOLIC ENGINEERING; Lugar: Amsterdam; Año: 2018
TOMASSETTI, MAURO; GARAVAGLIA, BETIANA S.; VRANYCH, CECILIA V.; GOTTIG, NATALIA; OTTADO, JORGELINA; GRAMAJO, HUGO; DIACOVICH, LAUTARO
3-Methylcrotonyl Coenzyme A (CoA) carboxylase complex is involved in the Xanthomonas citri subsp. Citri lifestyle during citrus infection
PLOS ONE; Año: 2018 vol. 13
GAGO, GABRIELA; DIACOVICH, LAUTARO; GRAMAJO, HUGO
Lipid metabolism and its implication in mycobacteria–host interaction
CURRENT OPINION IN MICROBIOLOGY; Año: 2018 vol. 41 p. 36 - 42
BAZET LYONNET B, DIACOVICH L, GAGO G, SPINA L, BARDOU F, LEMASSU A, QUÉMARD A, GRAMAJO H
Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits.
FEBS JOURNAL; Año: 2018
CABRUJA M, MONDINO S, TSAI YT, LARA J, GRAMAJO H, GAGO G
A conditional mutant of the fatty acid synthase unveils unexpected cross talks in mycobacterial lipid metabolism.
Open biology; Año: 2017
SIMÓN MENENDEZ-BRAVO, JULIÁN PAGANINI, CLAUDIO AVIGNONE-ROSSA, HUGO GRAMAJO, ANA ARABOLAZA
Identification of FadAB Complexes Involved in Fatty Acid b-Oxidation in Streptomyces coelicolor and Construction of a Triacylglycerol Overproducing strain
Frontiers in microbiology; Año: 2017
MENENDEZ-BRAVO S, COMBA S, GRAMAJO H, ARABOLAZA A
Metabolic engineering of microorganisms for the production of structurally diverse esters.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY; Lugar: Berlin; Año: 2017
YI TING TSAI, VALENTINA SALZMAN, MATÍAS CABRUJA, GABRIELA GAGO AND HUGO GRAMAJO.
Role of long-chain acyl-CoAs in the regulation of mycolic acid biosynthesis in mycobacteria.
open biology; Año: 2017
GAGO G, DIACOVICH L, GRAMAJO H
Lipid metabolism and its implication in mycobacteria-host interaction.
CURRENT OPINION IN MICROBIOLOGY; Año: 2017
EDILEUSA C.M. GERHARDT, VIVIAN R. MOURE, ANDREY W. SOUZA, FABIO O. PEDROSA, EMANUEL M. SOUZA, LAUTARO DIACOVICH, HUGO GRAMAJO, LUCIANO F. HUERGO
Exprssion and purification of untagged GlnK proteins from Actinobacteria
EXCLI JOURNAL; Año: 2017
ANAND BABU VELAPPAN, MAMILLA R. CHARAN RAJA, DHRUBAJYOTI DATTA, YI TING TSAI, IMAN HALLOUM, BAOJIE WAN, LAURENT KREMER, HUGO GRAMAJO, SCOTT G. FRANZBLAU, SANTANU KAR MAHAPATRA, JOY DEBNATH ; YITING TSAI AND GRAMAJO H,
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea
EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2016
CABRUJA M, LYONNET BB, MILLÁN G, GRAMAJO H, GAGO G
Analysis of coenzyme A activated compounds in actinomycetes.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY; Lugar: Berlin; Año: 2016
HERNÁNDEZ MA, LARA J, GAGO G, GRAMAJO H, ALVAREZ HM
The pleiotropic transcriptional regulator NlpR contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci.
MOLECULAR MICROBIOLOGY; Año: 2016
MENENDEZ-BRAVO S, ROULET J, SABATINI M, COMBA S, DUNN R, GRAMAJO H, ARABOLAZA A
High cell density production of multimethyl-branched long-chain esters in Escherichia coli and determination of their physicochemical properties.
BIOTECHNOLOGY FOR BIOFUELS; Lugar: Londres; Año: 2016
ANAND BABU VELAPPAN, MAMILLA R. CHARAN RAJA, DHRUBAJYOTI DATTA, YI TING TSAI, IMAN HALLOUM, BAOJIE WAN, LAURENT KREMER, HUGO GRAMAJO, SCOTT G. FRANZBLAU, SANTANU KAR MAHAPATRA, JOY DEBNATH
Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea
European Journal of Medicinal Chemistry; Año: 2016
DIACOVICH L, LORENZI L, TOMASSETTI M, MÉRESSE S, GRAMAJO H
The infectious intracellular lifestyle of Salmonella enterica relies on the adaptation to nutritional conditions within the Salmonella-containing vacuole.
virulence; Año: 2016
COMBA, S; ARABOLAZA, A. AND GRAMAJO, H.; HERNÁNDEZ MA, ALVAREZ HM
Overexpression of a phosphatidic acid phosphatase type 2 leads to an increase in triacylglycerol production in oleaginous Rhodococcus strains
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY; Lugar: Berlin; Año: 2015
NAVONE L;; MACAGNO JP; LICONA-CASSANI C; MARCELLIN E; NIELSEN LK; GRAMAJO, H; RODRIGUEZ, E
All R controls the Expression of Streptomyces coelicolor Allantoin Pathway Genes.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Lugar: Washington; Año: 2015
MACAGNO JP, LICONA-CASSANI C, MARCELLIN E, NIELSEN LK, GRAMAJO H, RODRIGUEZ E
All R controls the Expression of Streptomyces coelicolor Allantoin Pathway Genes.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Lugar: Washington; Año: 2015
MENENDEZ-BRAVO S, COMBA S, SABATINI M, ARABOLAZA A, GRAMAJO H.
Expanding the chemical diversity of natural esters by engineering a polyketide-derived pathway into Escherichia coli.
METABOLIC ENGINEERING; Lugar: Amsterdam; Año: 2014 vol. 14 p. 97 - 106
SANTIAGO COMBA, MARTÍN SABATINI, SIMÓN MENENDEZ-BRAVO, ANA ARABOLAZA, AND HUGO GRAMAJO
Engineering a Streptomyces coelicolor biosynthesis pathway into Escherichia coli for high yield triglyceride production
BIOTECHNOLOGY FOR BIOFUELS; Lugar: Londres; Año: 2014
BERNARDO BAZET LYONNET, LAUTARO DIACOVICH, MATÍAS CABRUJA, FABIENNE BARDOU, ANNAıK QUEMARD,GABRIELA GAGO, AND HUGO GRAMAJO
Pleiotropic Effect of AccD5 and AccE5 Depletion in Acyl-Coenzyme A Carboxylase Activity and in Lipid Biosynthesis in Mycobacteria
PLOS ONE; Lugar: San Francisco; Año: 2014
. MONDINO S, GAGO G, GRAMAJO H
Transcriptional regulation of fatty acid biosynthesis in mycobacteria.
MOLECULAR MICROBIOLOGY; Lugar: Londres; Año: 2013 vol. 89 p. 372 - 387
COMBA S, MENENDEZ-BRAVO S, ARABOLAZA A, GRAMAJO H
Identification and physiological characterization of phosphatidic acid phosphatase enzymes involved in triacylglycerol biosynthesis in Streptomyces coelicolor.
MICROBIAL CELL FACTORIES; Lugar: Londres; Año: 2013 vol. 12 p. 9 - 17
CHRISTOPHER D. GOODMAN,B MARIANA USEGLIO,A SALVADOR PEIRÚ,A GUILLERMO R. LABADIE,C GEOFFREY I. MCFADDEN,B EDUARDO RODRÍGUEZ,A HUGO GRAMAJO
Chemobiosynthesis of new antimalarial macrolides.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2013 vol. 57 p. 907 - 913
ASENCIÓN DIEZ MD, PEIRÚ S, DEMONTE AM, GRAMAJO H AND IGLESIAS AA
Characterization of recombinant UDP- and ADP-glucose pyrophosphorylases and glycogen synthase to elucidate glucose-1-phosphate partitioning into oligo- and polysaccharides in Streptomyces coelicolor.
JOURNAL OF BACTERIOLOGY; Lugar: Washington; Año: 2012 p. 1485 - 1493
RODRIGUEZ E, NAVONE L, CASATI P, GRAMAJO H
Impact of malic enzymes on antibiotic and triacylglycerol production in Streptomyces coelicolor.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Lugar: Washington; Año: 2012 vol. 78 p. 4571 - 4579
RAVASI P, PEIRU S, GRAMAJO H, MENZELLA HG
Design and testing of a synthetic biology framework for genetic engineering of Corynebacterium glutamicum.
MICROBIAL CELL FACTORIES; Lugar: Londres; Año: 2012 vol. 11 p. 147 - 153
HERNÁNDEZ MA, ARABOLAZA A, RODRÍGUEZ E, GRAMAJO H, ALVAREZ HM
The atf2 gene is involved in triacylglycerol biosynthesis and accumulation in the oleaginous Rhodococcus opacus PD630.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY; Lugar: Berlin; Año: 2012 vol. 97 p. 2119 - 2130
COMBA, S; ARABOLAZA, A. AND GRAMAJO, H.
Emerging engineering principles for yield improvement in microbial cell design
computational structural biotechnology journal; Año: 2012 vol. 3 p. 16 - 20
GAGO G, DIACOVICH L, ARABOLAZA A, TSAI SC, GRAMAJO H
Fatty acid biosíntesis in actinomycetes
FEMS MICROBIOLOGY REVIEWS; Lugar: Londres; Año: 2011 p. 475 - 497
ARABOLAZA A,; DANGELO, M; COMBA, S; GRAMAJO, H
FasR, a novel class of transcriptional regulator, governs the activation of fatty acid biosynthesis genes in Streptomyces coelicolor.
MOLECULAR MICROBIOLOGY; Lugar: Londres; Año: 2010 p. 47 - 63
SALZMAN, V., MONDINO, S., GAGO, G., GRAMAJO, HC
Transcriptional regulation of lipid homeostasis in mycobacteria
MOLECULAR MICROBIOLOGY; Lugar: Londres; Año: 2010 p. 64 - 77
USEGLIO M, ; PEIRU, S; RODRIGUEZ, E; LABADIE, GR; CARNEY, JR; GRAMAJO, HUGO CÉSAR
TDP-L-megosamine biosynthesis pathway elucidation and megalomicin a production in Escherichia coli
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Lugar: Washington; Año: 2010 p. 3869 - 3877
ANA ARABOLAZA, MARY ELIZABETH SHILLITO,TING-WAN LIN, LAUTARO DIACOVICH, MELROSE MELGAR, HUY PHAM, DEBORAH AMICK, HUGO GRAMAJO* AND SHIOU-CHUAN TSAI* G., AND GRAMAJO H.
Crystal Structures and Mutational Analyses of Acyl-CoA Carboxylase β Subunit of Streptomyces coelicolor
BIOCHEMISTRY; Lugar: Washington; Año: 2010 p. 7367 - 7376
PEIRÚ S.; GRAMAJO H. AND MENZELLA H
Recombinant approaches to large polyketide molecules as potential drugs.
DRUG DISCOVERY TODAY; Lugar: Amsterdam; Año: 2010 vol. 7 p. 105 - 113
S. PEIRÚ, H. GRAMAJO AND HG. MENZELLA
Design and synthesis of pathway genes for polyketide biosynthesis
METHODS IN ENZYMOLOGY.; Año: 2009 vol. 459 p. 319 - 337
E. RODRÍGUEZ, HG. MENZELLA AND H. GRAMAJO.
Heterologous production of polyketides in bacteria
METHODS IN ENZYMOLOGY.; Año: 2009 vol. 459 p. 339 - 364
SWAMIDASS, S.J., AZENCOTT, S.C., GRAMAJO, H., LIN, T.W., TSAI, S.C., AND BALDI, P.F.
The influence relevance voter: an accurate and interpretable virtual high throughput screening method
JOURNAL OF CHEMICAL INFORMATION AND MODELING; Año: 2009 p. 256 - 263
DANIEL KURTH, GABRIELA GAGO, TING-WAN LIN, AGUSTINA DE LA IGLESIA, HECTOR MORBIDONI, SHIOU-CHUAN TSAI AND HUGO GRAMAJO
ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria
MICROBIOLOGY-UK; Año: 2009 p. 2664 - 2672
ANA ARABOLAZA, EDUARDO RODRIGUEZ, SILVIA ALTABE, HECTOR ALVAREZ, AND HUGO GRAMAJO.
Multiple Pathways for Triacylglycerol Biosynthesis in Streptomyces coelicolor
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Año: 2008 vol. 74 p. 2573 - 2582
SALVADOR PEIRÚ, HUGO MENZELLA, EDUARDO RODRÍGUEZ, JOHN CARNEY AND HUGO GRAMAJO
Metabolically engineered Escherichia coli for efficient production of glycosylated natural products
Microbial Biotechnology; Año: 2008 vol. 1 p. 476 - 486
S. PEIRÚ, E. RODRÍGUEZ, C.Q. TRAN, J.E. CARNNEY AND H. GRAMAJO
Characterization of the heterodimeric MegBIIa:MegBIIb aldo-keto reductase involved in the biosynthesis of L-mycarose from Micromonospora megalomicea
BIOCHEMISTRY; Año: 2007 vol. 46 p. 4100 - 4109
WARD SL, DESAI RP, HU Z, GRAMAJO H, KATZ L
Precursor-directed biosynthesis of 6-deoxyerythronolide B analogues is improved by removal of the initial catalytic sites of the polyketide synthase.
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY; Lugar: HEIDELBERG; Año: 2007 vol. 34 p. 9 - 15
GAGO, G; KURTH, D; DIACOVICH, L; TSAI, S C; GRAMAJO, HUGO CÉSAR
Biochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosis
JOURNAL OF BACTERIOLOGY; Año: 2006 vol. 188 p. 477 - 486
LIN, T W; MELGAR, M M; KURTH, D; SWAMIDASS, S J; PURDON, J; TSENG, T; GAGO, G; BALDI, P; GRAMAJO, HUGO CÉSAR; TSAI, S C
Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2006 vol. 103 p. 3072 - 3077
HEARN, B R; ARSLANIAN, R L; FU, H; LIU, F; GRAMAJO, HUGO CÉSAR; MYLES, D C
Methanolysis products of disorazole A1
JOURNAL OF NATURAL PRODUCTS; Año: 2006 vol. 69 p. 148 - 150
RODRIGUEZ, E; PEIRU, S; CARNEY, J R; GRAMAJO, HUGO CÉSAR
In vivo characterization of the dTDP-D-desosamine pathway of the megalomicin gene cluster from Micromonospora megalomicea.
MICROBIOLOGY-UK; Año: 2006 vol. 152 p. 667 - 673
ANA ARABOLAZA,; CLAUDIA BANCHIO,; GRAMAJO, HUGO CÉSAR
Transcriptional regulation of the macs1-fadD1 operon encoding two acyl-CoA synthases involved in the physiological differentiation of Streptomyces coelicolor
MICROBIOLOGY; Año: 2006 vol. 152 p. 1427 - 1439
SALVADOR PEIRÚ, HUGO MENZELLA, EDUARDO RODRÍGUEZ, JOHN CARNEY AND HUGO GRAMAJO
Production of the potent antibacterial polyketide erythromycin C in Escherichia coli
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Año: 2005 p. 2539 - 2547
CARVALHO, R., REID R., GRAMAJO, H. AND BRIAN JULIEN.
The biosynthetic genes for disorazoles, potent cytotoxic compounds that disrupt microtubule formation
GENE; Año: 2005 p. 91 - 98
ZHIHAO HU, RALPH REID, HUGO GRAMAJO
The Leptomycin Gene Cluster and Its Heterologous Expression in Streptomyces lividans
JOURNAL OF ANTIBIOTICS; Año: 2005 p. 625 - 633
GAGO G, KURTH D, DIACOVICH L, TSAI SC, GRAMAJO H.
Biochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosis
JOURNAL OF BACTERIOLOGY; Año: 2005
DIACOVICH, L; MITCHELL, D L; PHAM, H; GAGO, G; MELGAR, MM; KHOSLA, C; GRAMAJO, HUGO CÉSAR; TSAI, SC
Crystal structure of the beta-subunit of acyl-CoA carboxylase: structure-based engineering of substrate specificity
BIOCHEMISTRY; Año: 2005 vol. 43 p. 14027 - 14036
HUGO G. MENZELLA AND HUGO C. GRAMAJO
Recombinant Protein Production in High Cell Density Cultures of Escherichia coli with Galactose as a Gratuitous Inducer
BIOTECHNOLOGY PROGRESS; Año: 2004 p. 1263 - 1266
LAUTARO DIACOVICH, DEBORAH MITCHELL, HUY PHAM, GABRIELA GAGO, MELROSE MELGAR, CHAITAN KHOSLA, HUGO GRAMAJO, SHIOU-CHUAN TSAI
Crystal Structure of the Beta Subunit of Acyl-CoA Carboxylase: Structure Based Engineering of Substrate Specificity
BIOCHEMISTRY; Año: 2004 p. 14027 - 14036
NOVOTNA, J; VOHRADSKY, J; BERNDT, P; GRAMAJO, HUGO CÉSAR; LANGEN, H; LI, X; MINAS, W; OSARIA, L; ROEDER, D; THOMPSON, C
Proteomic studies of diauxic lag in the differentiating prokaryote Streptomyces coelicolor reveal a regulatory network of stress-induced proteins and central metabolic enzymes
MOLECULAR MICROBIOLOGY; Año: 2003 vol. 48 p. 1289 - 1303
MENZELLA, H; CECCARELLI, E; GRAMAJO, HUGO CÉSAR
A novel Escherichia coil allows efficient recombinant protein production using lactose as inducer
BIOENGINEERING AND BIOTECHNOLOGY; Año: 2003 vol. 82 p. 808 - 817
MENZELLA, H; GRAMAJO, HUGO CÉSAR; CECCARELLI, E
High recovery of prochymosin from inclusion bodies using controlled air oxidation
PROTEIN EXPRESSION AND PURIFICATION; Año: 2002 vol. 25 p. 248 - 255
BANCHIO, C; GRAMAJO, HUGO CÉSAR
A stationary-phase acyl-coenzyme A synthetase of Streptomyces coelicolor A3(2) is necessary for the normal onset of antibiotic production
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Año: 2002 vol. 69 p. 4240 - 4246
DIACOVICH, L; PEIRU, S; KURTH, D; RODRIGUEZ, E; PODESTA, E; KHOSLA, C; GRAMAJO, HUGO CÉSAR
Kinetic and structural analysis of a new group of Acyl-CoA carboxylases found in Streptomyces coelicolor A3(2)
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2002 vol. 277 p. 1 - 1
RODRIGUEZ, E; BANCHIO, C; DIACOVICH, L; BIBB, M; GRAMAJO, HUGO CÉSAR
Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2)
APPLIED AND ENVIRONMENTAL MICROBIOLOGY; Año: 2001 vol. 67 p. 4166 - 4176
PFEIFER, B A; ADMIRAL, S J; GRAMAJO, HUGO CÉSAR; CANE, D; KHOSLA, C
Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli.
SCIENCE; Año: 2001 vol. 291 p. 1790 - 1792
RODRIGUEZ, E; GRAMAJO, HUGO CÉSAR
Genetic and biochemical characterization of the alpha and beta components of a propionyl-CoA carboxylase complex of Streptomyces coelicolor A3(2)
MICROBIOLOGY; Año: 1999 vol. 145 p. 3109 - 3119
OSARIA, L; PAOLETI, L; GRAMAJO, HUGO CÉSAR
Characterization of stationary-phase proteins in S. coelicolor A(3)2
FEMS MICROBIOLOGY LETTERS; Año: 1998 vol. 162 p. 275 - 281
GRAMAJO, HUGO CÉSAR; SHUJMAN, G; GRAU, R; ORNELLA, L; DE MENDOZA, D
De novo fatty acid synthesisi is requiered for establishment of cell type-specific gene transcription during sporulation
MOLECULAR MICROBIOLOGY; Año: 1998 vol. 29 p. 1215 - 1224
BANCHIO, C; GRAMAJO, HUGO CÉSAR
Medium- and long-chain fatty acid uptake and utilization by Streptomyces coelicolor A3(2): first characterization of a gram-positive bacterial system
MICROBIOLOGY; Año: 1997 vol. 143 p. 2439 - 2447
FUJII, T; GRAMAJO, HUGO CÉSAR; TAKANO, E; BIBB, M
redD and actII-ORF4, pathway-specific regulatory genes for antibiotic production in Streptomyces coelicolor A3(2), are transcribed in vitro by an RNA polymerase holoenzyme containing sigma hrdD
JOURNAL OF BACTERIOLOGY; Año: 1996 vol. 178 p. 3402 - 3405
GRAMAJO, HUGO CÉSAR; TAKANO, E; BIBB, M
Stationary-phase production of the antibiotic actinorhodin in Streptomyces coelicolor A3(2) is transcriptionally regulated
MOLECULAR MICROBIOLOGY; Año: 1993 vol. 7 p. 837 - 845
GARDIOL, D; GRAMAJO, HUGO CÉSAR; HIRSHBEIN, L; DE MENDOZA, D
Application of the mini-mu phage for the isolation of lac transcriptional fusions in Bacillus subtilis genes.
GENE; Año: 1993 vol. 123 p. 39 - 44
TAKANO, E; GRAMAJO, HUGO CÉSAR; STRAUCH, E; ANDRES, N; WHITE, J; BIBB, M
Transcriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2).
MOLECULAR MICROBIOLOGY; Año: 1992 vol. 6 p. 2797 - 2804
SHEN, B; SUMMERS, R; GRAMAJO, HUGO CÉSAR; BIBB, M; HUTCHINSON, R
Purification and characterization of the acyl carrier protein of the Streptomyces glaucescens tetracenomycin C polyketide synthase.
JOURNAL OF BACTERIOLOGY; Año: 1992 vol. 174 p. 3818 - 3821
GRAMAJO, HUGO CÉSAR; WHITE, J; HUTCHINSON, R; BIBB, M
Overproduction and localization of components of the polyketide synthase of Streptomyces glaucescens involved in the production of the antibiotic tetracenomycin C.
JOURNAL OF BACTERIOLOGY; Año: 1991 vol. 173 p. 6475 - 6483
GRAMAJO, HUGO CÉSAR; VIALE, A; DE MENDOZA, D
Expression of cloned genes by in vivo insertion of tac promoter using a mini-Mu bacteriophage
GENE; Año: 1988 vol. 65 p. 305 - 314
GRAMAJO, HUGO CÉSAR; DE MENDOZA, D
A cos-mini-Mu vector for in vivo DNA cloning
GENE; Año: 1987 vol. 51 p. 85 - 90
DE MENDOZA, D; GRAMAJO, HUGO CÉSAR; ROSA, A
In vivo cloning of DNA into multicopy cosmids by mini-Mu-cosduction.
MOLECULAR AND GENERAL GENETICS; Año: 1986 vol. 205 p. 546 - 549