INVESTIGADORES
LEBLANC Jean Guy Joseph
artículos
Título:
Probiotics and Trained Immunity
Autor/es:
CORTES-PERES, N.G.; DE MORENO DE LEBLANC, ALEJANDRA; GOMEZ-GUTIERREZ, J.; LEBLANC, JEAN GUY; BERMUDEZ-HUMARAN, L.
Revista:
Biomolecules
Editorial:
MDPI
Referencias:
Lugar: Basel; Año: 2021 vol. 11 p. 1 - 23
ISSN:
2218-273X
Resumen:
Abstract: The characteristics of innate immunity have recently been investigated in depth in severalresearch articles, and original findings suggest that innate immunity also has a memory capacitywhich has been named ?trained immunity?. This notion has revolutionized our knowledge of theinnate immune response. Thus, stimulation of trained immunity represents a therapeutic alternativethat is worth exploring. In this context, probiotics, live microorganisms which when administeredin adequate amounts confer a health benefit on the host, represent attractive candidates forstimulation of trained immunity; however, although numerous studies have documented the beneficialproprieties of these microorganisms, their mechanisms of action are not yet fully understood.In this review we propose to explore the putative connection between probiotics and stimulationof trained immunity.
