MARÍA M. CORVI ; FRANCO ROSSI; AGUSTINA GANUZA; ANDRÉS A. ALONSO; LUCAS N ALBERCA; ROQUE DIETRICH; LUCIANA GAVERNET; TALEVI, ALAN

Triclabendazole and clofazimine reduce replication and spermine uptake in vitro in Toxoplasma gondii

Parasitology Research; Año: 2024 vol. 123

TALEVI, ALAN; BELLERA, CAROLINA L.

Clustering of small molecules: new perspectives and their impact on natural product lead discovery

Frontiers in Natural Products; Año: 2024 vol. 3

MORALES, J. FRANCISCO; RUIZ, M. ESPERANZA; STRATFORD, ROBERT E.; TALEVI, ALAN

Application of machine learning to predict unbound drug bioavailability in the brain

Frontiers in Drug Discovery; Año: 2024 vol. 4

PRADA GORI, DENIS N.; ALBERCA, LUCAS N.; TALEVI, ALAN

Making the most effective use of available computational methods for drug repositioning

EXPERT OPINION ON DRUG DISCOVERY; Año: 2023 p. 1 - 9

LLANOS, MANUEL A.; ENRIQUE, NICOLÁS; ESTEBAN-LÓPEZ, VEGA; SCIOLI-MONTOTO, SEBASTIAN; SÁNCHEZ-BENITO, DAVID; RUIZ, MARÍA E.; MILESI, VERONICA; LÓPEZ, DOLORES E.; TALEVI, ALAN; MARTÍN, PEDRO; GAVERNET, LUCIANA

A Combined Ligand- and Structure-Based Virtual Screening To Identify Novel NaV1.2 Blockers: In Vitro Patch Clamp Validation and In Vivo Anticonvulsant Activity

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Año: 2023 vol. 63 p. 7083 - 7096

RIVERO BERTI, IGNACIO; GANTNER, MELISA E.; RODRIGUEZ, SANTIAGO; ISLAN, GERMAN A.; FÁVARO, WAGNER J.; TALEVI, ALAN; CASTRO, GUILLERMO R.; DURÁN, NELSON

Potential biocide roles of violacein

Frontiers in Nanotechnology; Año: 2023 vol. 5

LLANOS, MANUEL A.; ALBERCA, LUCAS N.; RUIZ, MARÍA D.; SBARAGLINI, MARÍA L.; MIRANDA, CRISTIAN; PINO-MARTINEZ, AGUSTINA; FRACCAROLI, LAURA; CARRILLO, CAROLINA; ALBA SOTO, CATALINA D.; GAVERNET, LUCIANA; TALEVI, ALAN

A combined ligand and target-based virtual screening strategy to repurpose drugs as putrescine uptake inhibitors with trypanocidal activity

J. COMPUT. AIDED MOL. RESIGN; Año: 2023 vol. 37 p. 75 - 90

PRADA GORI, DENIS N.; RUATTA, SANTIAGO; FLÓ, MARTÍN; ALBERCA, LUCAS N.; BELLERA, CAROLINA L.; PARK, SOONJU; HEO, JINYEONG; LEE, HONGGUN; PARK, KYU-HO PAUL; PRITSCH, OTTO; SHUM, DAVID; COMINI, MARCELO A.; TALEVI, ALAN

Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease

Frontiers in Drug Discovery; Año: 2023 vol. 2

GAROFALO, FEDERICO M; SBARAGLINI, MARÍA L; BARRIONUEVO, EMILIA M; PERALTA, ESTEFANÍA; BONIFAZI, EVELYN L; TALEVI, ALAN; GAVERNET, LUCIANA

Synthesis and biological evaluation of new antiseizure compounds derived from valproic acid

Future Medicinal Chemistry; Año: 2023

RUATTA, SANTIAGO M.; PRADA GORI, DENIS N.; FLÓ DÍAZ, MARTÍN; LORENZELLI, FRANCA; PERELMUTER, KAREN; ALBERCA, LUCAS N.; BELLERA, CAROLINA L.; MEDEIROS, ANDREA; LÓPEZ, GLORIA V.; INGOLD, MARIANA; PORCAL, WILLIAMS; DIBELLO, ESTEFANÍA; IHNATENKO, IRINA; KUNICK, CONRAD; INCERTI, MARCELO; LUZARDO, MARTÍN; COLOBBIO, MAXIMILIANO; RAMOS, JUAN CARLOS; MANTA, EDUARDO; MININI, LUCÍA; LAVAGGI, MARÍA LAURA; HERNÁNDEZ, PAOLA; SARLAUSKAS, JONAS; HUERTA GARCÍA, CÉSAR SEBASTIAN; CASTILLO, RAFAEL; HERNÁNDEZ-CAMPOS, ALICIA; RIBAUDO, GIOVANNI; ZAGOTTO, GIUSEPPE; CARLUCCI, RENZO; MEDRÁN, NOELIA S.; LABADIE, GUILLERMO R.; MARTINEZ-AMEZAGA, MAITENA; DELPICCOLO, CARINA M. L.; MATA, ERNESTO G.; SCARONE, LAURA; POSADA, LAURA; SERRA, GLORIA; CALOGEROPOULOU, THEODORA; PROUSIS, KYRIAKOS; DETSI, ANASTASIA; CABRERA, MAURICIO; ALVAREZ, GUZMÁN; AICARDO, ADRIÁN; ARAÚJO, VERENA; CHAVARRÍA, CECILIA; MACIC, LUCIJA PETERLIN; GANTNER, MELISA E.; LLANOS, MANUEL A.; RODRÍGUEZ, SANTIAGO; GAVERNET, LUCIANA; PARK, SOONJU; HEO, JINYEONG; LEE, HONGGUN; PA

Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro

Frontiers in Pharmacology; Año: 2023 vol. 14

MURACA, GIULIANA; RUIZ, MARÍA ESPERANZA; GAMBARO, ROCÍO C; SCIOLI-MONTOTO, SEBASTIÁN; SBARAGLINI, MARÍA LAURA; PADULA, GISEL; CISNEROS, JOSÉ SEBASTIÁN; CHAIN, CECILIA YAMIL; ÁLVAREZ, VERA A; HUCK-IRIART, CRISTIÁN; CASTRO, GUILLERMO R; PIÑERO, MARÍA BELÉN; MARCHETTO, MATIAS ILDEBRANDO; ALBA SOTO, CATALINA; ISLAN, GERMÁN A; TALEVI, ALAN

Nanostructured lipid carriers containing benznidazole: physicochemical, biopharmaceutical and cellular in vitro studies

Beilstein Journal of Nanotechnology; Año: 2023 vol. 14 p. 804 - 818

PRADA GORI, DENIS ; LLANOS, MANUEL A.; BELLERA, CAROLINA L.; TALEVI, ALAN; ALBERCA, LUCAS N.

iRaPCA and SOMoC: Development and Validation of Web Applications for New Approaches for the Clustering of Small Molecules

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Lugar: Washington; Año: 2022

LLANOS, MANUEL A.; ENRIQUE, NICOLÁS; SBARAGLINI, MARÍA L.; GARÓFALO, FEDERICO; TALEVI, ALAN; GAVERNET, LUCIANA; MARTIN, PEDRO

Structure-Based Virtual Screening Identifies Novobiocin, Montelukast, and Cinnarizine as TRPV1 Modulators with Anticonvulsant Activity In Vivo

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Lugar: Washington; Año: 2022

GORI, DENIS N. PRADA; ALBERCA, LUCAS N.; RODRIGUEZ, SANTIAGO; ALICE, JUAN I.; LLANOS, MANUEL A.; BELLERA, CAROLINA L.; TALEVI, ALAN

LIDeB Tools: A Latin American resource of freely available, open-source cheminformatics apps

Artificial Intelligence in the Life Sciences; Año: 2022 vol. 2

TALEVI, ALAN

Antiseizure medication discovery: Recent and future paradigm shifts

Epilepsia Open; Año: 2022

HERNÁNDEZ GONZÁLEZ, JORGE ENRIQUE; ALBERCA, LUCAS N.; MASFORROL GONZÁLEZ, YORDANKA; REYES ACOSTA, OSVALDO; TALEVI, ALAN; SALAS-SARDUY, EMIR

Tetracycline Derivatives Inhibit Plasmodial Cysteine Protease Falcipain-2 through Binding to a Distal Allosteric Site

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Lugar: Washington; Año: 2022

LLANOS, MANUEL A.; ALBERCA, LUCAS N.; VILCHEZ LARREA, SALOMÉ; SCHOIJET, ALEJANDRA; ALONSO, GUILLERMO; BELLERA, CAROLINA L.; GAVERNET, LUCIANA; TALEVI, ALAN

Homology Modeling and Molecular Dynamics Simulations of Trypanosoma cruzi Phosphodiesterase b1

Chemistry and Biodiversity; Lugar: Weinheim; Año: 2022 vol. 19 p. 159 - 175

ALAN TALEVI

Potential Medicinal Effects and Applications of Stevia Constituents

PHYTOCHEMISTRY REVIEWS; Lugar: Berlin; Año: 2022 vol. 21 p. 161 - 178

SCIOLI MONTOTO, S.; SBARAGLINI, M.L.; CISNEROS, J.S.; CHAIN, C.Y. ; FERRETI, V. ; LEÓN, I. ; ALVAREZ, V.A.; CASTRO, G.R.; ISLAN, G.A.; TALEVI, A. ; DANIELA RUIZ

Novel Phenobarbital-loaded nanostructured lipid carriers for epilepsy treatment: from QbD to in vivo evaluation

Frontiers in Chemistry; Año: 2022

GANTNER, MELISA E.; PRADA GORI, DENIS N.; LLANOS, MANUEL A.; TALEVI, ALAN; ANGELI, ANDREA; VULLO, DANIELA; SUPURAN, CLAUDIU T.; GAVERNET, LUCIANA

Identification of New Carbonic Anhydrase VII Inhibitors by Structure-Based Virtual Screening

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Año: 2022 vol. 62 p. 4760 - 4770

TALEVI, ALAN; DURAN, NELSON; CASTRO, GUILLERMO RAUL

Editorial: Lipid Nanoparticles as a Novel Strategy to Deliver Bioactive Molecules

Frontiers in Chemistry; Año: 2021 vol. 9

SCIOLI MONTOTO, S.; MURACA GIULIANA; DI IANNI, MAURICIO E.; MANUEL COUYOUPETROU; GUIDO PESCE; ISLAN, G.A.; YAMIL CHAIN; MARÍA ELENA VELA; MARÍA E. RUIZ; ALAN TALEVI; CASTRO GUILLERMO R.

Physicochemical and Biopharmaceutical Characterization of Oxcarbazepine-loaded Nanoestructured Lipid Carriers as potential antiepileptic devices

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY; Año: 2021 vol. 63

LLANOS, MANUEL A.; GANTNER, MELISA E.; RODRIGUEZ, SANTIAGO; ALBERCA, LUCAS N.; BELLERA, CAROLINA L.; TALEVI ALAN; GAVERNET, LUCIANA

Strengths and weaknesses of docking simulations in the SARS-CoV-2 era: the main protease (Mpro) case study

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Lugar: Washington; Año: 2021

JUAN I. ALICE; CAROLINA L. BELLERA; DIEGO BENÍTEZ; MARCELO COMINI; PABLO R. DUCHOWICZ; TALEVI, ALAN

Ensemble learning application to discover new trypanothione synthetase inhibitors

MOLECULAR DIVERSITY; Lugar: Berlin; Año: 2021 vol. 25 p. 1361 - 1373

ENRIQUE, ANDREA VERÓNICA; DI IANNI, MAURICIO EMILIANO; GOICOECHEA, SOFÍA; LAZAROWSKI, ALBERTO; VALLE-DORADO, MARÍA GUADALUPE; COSTA, JUAN JOSÉ LÓPEZ; ROCHA, LUISA; GIRARDI, ELENA; TALEVI, ALAN

New anticonvulsant candidates prevent P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure model in mice

EPILEPSY & BEHAVIOR (PRINT); Lugar: Amsterdam; Año: 2021 vol. 121

ANDREA V. ENRIQUE; PEDRO MARTIN ; MARÍA L. SBARAGLINI; TALEVI, ALAN; VERÓNICA MILESI

Parabens inhibit hNaV 1.2 channels

BIOMEDICINE & PHARMACOTHERAPY = BIOMEDECINE & PHARMACOTHERAPIE.; Lugar: Paris; Año: 2020 vol. 128

TALEVI, ALAN; MORALES, JUAN FRANCISCO; HATHER, GREGORY; PODICHETTY, JAGDEEP T.; KIM, SARAH; BLOOMINGDALE, PETER C.; KIM, SAMUEL; BURTON, JACKSON; BROWN, JOSHUA D.; WINTERSTEIN, ALMUT G.; SCHMIDT, STEPHAN; WHITE, JENSEN KAEL; CONRADO, DANIELA J.

Machine Learning in Drug Discovery and Development Part 1: A Primer

CPT: Pharmacometrics & Systems Pharmacology; Año: 2020 vol. 9 p. 129 - 142

BELLERA, CAROLINA L.; ALBERCA, LUCAS N.; SBARAGLINI, MARÍA L.; TALEVI, ALAN

In Silico Drug Repositioning for Chagas Disease

CURRENT MEDICINAL CHEMISTRY.; Año: 2020 vol. 27 p. 662 - 675

MORALES, JUAN F.; CHUGURANSKY, SARA; ALBERCA, LUCAS N.; ALICE, JUAN I.; GOICOECHEA, SOFÍA; RUIZ, MARÍA E.; BELLERA, CAROLINA L.; TALEVI, ALAN

Positivity Predictive Value surfaces as a complementary tool to assess the performance of virtual screening methods

MINI-REVIEWS IN MEDICINAL CHEMISTRY; Año: 2020 vol. 20

AUZMENDI, JERÓNIMO; PALESTRO, PABLO; BLACHMAN, AGUSTÍN; GAVERNET, LUCIANA; MERELLI, AMALIA; TALEVI, ALAN; CALABRESE, GRACIELA CRISTINA; RAMOS, ALBERTO JAVIER; LAZAROWSKI, ALBERTO

Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions

Frontiers in Behavioral Neuroscience; Año: 2020 vol. 14

LLANOS, MANUEL A.; SBARAGLINI, MARÍA L.; VILLALBA, MARÍA L.; RUIZ, MARÍA D.; CARRILLO, CAROLINA; SOTO, CATALINA ALBA; TALEVI, ALAN; ANGELI, ANDREA; PARKKILA, SEPPO; SUPURAN, CLAUDIU T.; GAVERNET, LUCIANA

A structure-based approach towards the identification of novel antichagasic compounds: Trypanosoma cruzi carbonic anhydrase inhibitors

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY; Lugar: Londres; Año: 2020 vol. 35 p. 21 - 30

MARÍA L. SBARAGLINI; SARA CHUGURANSKY; PABLO PALESTRO; LUCIANA GAVERNET; ALAN TALEVI; GUADALUPE GARCÍA LIÑARES

Lipase Catalyzed Synthesis of Alkyl Phenylacetates with Anticonvulsant Activity

Latin American Journal of Pharmacy; Año: 2020

MURACA GIULIANA; RIVERO BERTI IGNACIO; SBARAGLINI MARÍA L; WAGNER FAVARO; DURÁN NELSON ; CASTRO GUILLERMO R. ; TALEVI ALAN

Trypanosomatid-Caused Conditions: State of the Art of Therapeutics and Potential Applications of Lipid-Based Nanocarriers

Frontiers in Chemistry; Año: 2020 vol. 26

BELLERA, CAROLINA L.; LLANOS, MANUEL; GANTNER, MELISA E.; RODRIGUEZ, SANTIAGO; GAVERNET, LUCIANA; COMINI, MARCELO; TALEVI, ALAN

Can drug repurposing strategies be the solution to the COVID-19 crisis?

EXPERT OPINION ON DRUG DISCOVERY; Año: 2020

BÉLGAMO, JULIÁN A.; ALBERCA, LUCAS N.; PÓRFIDO, JORGE L.; ROMERO, FRANCO N. CARAM; RODRIGUEZ, SANTIAGO; TALEVI, ALAN; CÓRSICO, BETINA; FRANCHINI, GISELA R.

Application of target repositioning and in silico screening to exploit fatty acid binding proteins (FABPs) from Echinococcus multilocularis as possible drug targets

J. COMPUT. AIDED MOL. RESIGN; Año: 2020 vol. 34 p. 1275 - 1288

TALEVI, ALAN; BELLERA, CAROLINA L.

Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics

EXPERT OPINION ON DRUG DISCOVERY; Año: 2019 vol. 15 p. 397 - 401

BELLERA CAROLINA L; ALAN TALEVI

Quantitative structure-activity relationship models for compounds with anti-convulsant activity

EXPERT OPINION ON DRUG DISCOVERY; Lugar: London; Año: 2019

LUCAS N. ALBERCA; SARA R. CHUGURANSKY; CORA L. ÁLVAREZ ; ALAN TALEVI; EMIR SALAS SURDUY

In silico guided drug repurposing: discovery of new competitive and noncompetitive inhibitors of falcipain-2

Frontiers in Chemistry; Año: 2019

RODENAK-KLADNIEW, B.; MONTOTO, S. SCIOLI; SBARAGLINI, M.L.; IANNI, M. DI; RUIZ, M.E.; TALEVI, A.; ALVAREZ, V.A.; DURÁN, N.; CASTRO, G.R.; ISLAN, G.A.

Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties

INTERNATIONAL JOURNAL OF PHARMACEUTICS; Lugar: Amsterdam; Año: 2019

SBARAGLINI, MARÍA L.; BELLERA, CAROLINA L.; BRAGHINI, JUAN QUARROZ; ARECO, YÉSICA; MIRANDA, CRISTIAN; CARRILLO, CAROLINA; KELLY, JAZMÍN; BUCHHOLZ, BRUNO; GELPI, RICARDO J.; TALEVI, ALAN; ALBA SOTO, CATALINA D.

Combined therapy with Benznidazole and repurposed drugs Clofazimine and Benidipine for chronic Chagas disease

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2019

BELLERA CAROLINA L; SBARAGLINI MARÍA L; TALEVI ALAN

Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases

Current Topics in Medicinal Chemistry; Lugar: Oak Park; Año: 2018 vol. 18 p. 369 - 381

DIETRICH, R.C.; ALBERCA, L.N.; RUIZ, M.D.; PALESTRO, P.H.; C, CARRILLO; TALEVI, A.; GAVERNET, L.

Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Año: 2018 vol. 149 p. 22 - 29

SCIOLI MONTOTO, S.; SBARAGLINI, M.L.; TALEVI, A.; COUYOUPETROU, M.; DI IANNI, M.; PESCE, G.O.; ALVAREZ, V.A.; BRUNO-BLANCH, L.E.; CASTRO, G.R.; RUIZ, M.E.; ISLAN, G.A.

Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: physicochemical characterization and in vitro / in vivo evaluation

COLLOIDS AND SURFACES B-BIOINTERFACES; Lugar: Amsterdam; Año: 2018 vol. 167 p. 73 - 81

ALBERCA, LUCAS N.; SBARAGLINI, MARÍA L.; MORALES, JUAN F.; DIETRICH, ROQUE; RUIZ, MARÍA D.; PINO MARTÍNEZ, AGUSTINA M.; MIRANDA, CRISTIAN G.; FRACCAROLI, LAURA; ALBA SOTO, CATALINA D.; CARRILLO, CAROLINA; PALESTRO, PABLO H.; TALEVI, ALAN

Cascade Ligand- and Structure-Based Virtual Screening to Identify New Trypanocidal Compounds Inhibiting Putrescine Uptake

Frontiers in Cellular and Infection Microbiology; Año: 2018 vol. 8

ALAN TALEVI

Drug repositioning: current approaches and their implications in the precision medicine era

Expert Review of Precision Medicine and Drug Development; Año: 2018 vol. 3 p. 49 - 61

JUAN F. MORALES; LUCAS N. ALBERCA; MAURICIO E. DI IANNI; SARA CHUGURANSKY; ALAN TALEVI; MARÍA E. RUIZ

Molecular topology and other promiscuity determinants as predictors of therapeutic Class? A theoretical framework to guide drug repositioning?

Current Topics in Medicinal Chemistry; Lugar: Oak Park; Año: 2018 vol. 18 p. 1110 - 1122

ALAN TALEVI; CAROLINA CARRILLO; MARCELO COMINI

The thiol-polyamine metabolism of Trypanosoma cruzi: molecular targets and drug repurposing strategies

CURRENT MEDICINAL CHEMISTRY.; Lugar: Oak Park; Año: 2018

MARÍA L. SBARAGLINI; ALAN TALEVI

Hybrid compounds as anti-infective agents.

Current Topics in Medicinal Chemistry; Lugar: Oak Park; Año: 2017 vol. 17 p. 1080 - 1095

MELISA E. GANTNER; ROXANA PERONI; JUAN F. MORALES; MARÍA L. VILLALBA; MARÍA E. RUIZ; ALAN TALEVI

Development and validation of a computational model ensemble for the early detection of BCRP/ABCG2 substrates during the drug design stage

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Lugar: Washington; Año: 2017 vol. 57

BELLERA, CAROLINA L.; DI IANNI, MAURICIO E.; TALEVI, ALAN

The application of molecular topology for ulcerative colitis drug discovery

EXPERT OPINION ON DRUG DISCOVERY; Año: 2017 vol. 13 p. 87 - 101

MANUEL COUYOUPETROU; MELISA E. GANTNER; MAURICIO E. DI IANNI; PABLO H. PALESTRO; ANDREA V. ENRIQUE; LUCIANA GAVERNET; MARÍA E. RUIZ; GUIDO PESCE; LUIS E. BRUNO-BLANCH; ALAN TALEVI

Computer-Aided Recognition of ABC Transporters Substrates and Its Application to the Development of New Drugs for Refractory Epilepsy

MINI-REVIEWS IN MEDICINAL CHEMISTRY; Lugar: Oak Park; Año: 2017 vol. 17 p. 205 - 215

ANTONELLA PISERA FUSTER; SOFÍA OTERO; ALAN TALEVI; LUIS E. BRUNO-BLANCH; RAMÓN BERNABEU

Anticonvulsant effect of Sodium cyclamate and propylparaben on PTZ-induced seizures in zebrafish

SYNAPSE; Lugar: New York; Año: 2017 vol. 71

CESAR EMMANUEL SANTANA-GÓMEZ; SANDRA A. OROZCO-SUÁREZ; ALAN TALEVI; LUIS E. BRUNO-BLANCH; VÍCTOR MANUEL MAGDALENO-MADRIGAL; RODRIGO FERNÁNDEZ-MÁS; LUISA L. ROCHA ARRIETA

Propylparaben applied after pilocarpine-induced status epilepticus modifies hippocampal excitability and glutamate release in rats

NEUROTOXICOLOGY; Lugar: Amsterdam; Año: 2017 vol. 59 p. 110 - 120

DI IANNI MAURICIO E; GERMÁN A. ISLAN; YAMIL CHAIN; GUILLERMO R. CASTRO; ALAN TALEVI; MARÍA ELENA VELA

Interaction of Solid Lipid Nanoparticles and specific proteins of the corona studied by Surface Plasmon Resonance

JOURNAL OF NANOMATERIALS; Lugar: New York; Año: 2017 vol. 2017

GERMÁN A. ISLAN; MARÍA E. RUIZ; JUAN F. MORALES; MARÍA L. SBARAGLINI; ANDREA V. ENRIQUE; GERARDO BURTON; ALAN TALEVI; LUIS E. BRUNO-BLANCH; GUILLERMO R. CASTRO

Hybrid inhalable microparticles for dual controlled release of levofloxacin and DNase: Physicochemical characterization and in-vivo targeted delivery to the lungs

Journal of Materials Chemistry B; Lugar: CAMBRIDGE; Año: 2017 vol. 5 p. 3132 - 3144

MELISA E. GANTNER; LUCAS N. ALBERCA; ANDREW MERCADER; LUIS E. BRUNO-BLANCH; ALAN TALEVI

Integrated Application of Enhanced Replacement Method and Ensemble Learning for the Prediction of BCRP/ABCG2 Substrates

CURRENT BIOINFORMATICS; Lugar: Oak Park; Año: 2017 vol. 12 p. 239 - 248

ALAN TALEVI

Computational approaches for innovative antiepileptic drug discovery

EXPERT OPINION ON DRUG DISCOVERY; Lugar: London; Año: 2016 vol. 11 p. 1001 - 1016

ALAN TALEVI

The Importance of Bioactivation in Computer-Guided Drug Repositioning. Why the Parent Drug is Not Always Enough

Current Topics in Medicinal Chemistry; Lugar: Oak Park; Año: 2016 vol. 16 p. 2078 - 2087

MARÍA L. VILLALBA; PABLO PALESTRO; MARIANGELA CERUSO; JOSÉ L. GONZÁLEZ FUNES ; ALAN TALEVI; LUIS E. BRUNO-BLANCH; CALUDIU T. SUPURAN; LUCIANA GAVERNET

Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2016 vol. 24 p. 894 - 901

LUCAS N. ALBERCA; MARÍA L. SBARAGLINI; DARÍO E. BALCAZAR; LAURA FRACCAROLI; CAROLINA CARRILLO; ANDREA MEDEIROS; DIEGO BENÍTEZ; MARCELO COMINI; ALAN TALEVI

Discovery of Novel Polyamine Analogs with anti-Protozoal Activity by Computer Guided Drug Repositioning.

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN; Lugar: Berlin; Año: 2016 vol. 30 p. 305 - 321

MARÍA L. SBARAGLINI; MARÍA C. VANRELL; CAROLINA L. BELLERA; GUSTAVO BENAIM; CAROLINA CARRILLO; ALAN TALEVI; PATRICIA S. ROMANO

Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option

Current Topics in Medicinal Chemistry; Lugar: Oak Park; Año: 2016 vol. 16 p. 2201 - 2222

MARÍA L. SBARAGLINI; CAROLINA L. BELLERA; LAURA FRACCAROLI; LUCIANA LAROCCA; CAROLINA CARRILLO; ALAN TALEVI; CATALINA ALBA SOTO

Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS; Lugar: Amsterdam; Año: 2016 vol. 48 p. 91 - 95

ALAN TALEVI

Tailored Multi-target Agents. Applications and Design Considerations

CURRENT PHARMACEUTICAL DESIGN.; Lugar: Oak Park; Año: 2016 vol. 22 p. 3164 - 3170

MAURICIO E. DI IANNI; MARÍA ELENA DEL VALLE; ANDREA V. ENRIQUE; MARÍA A. ROSELLA; FIORELLA BRUNO; LUIS E. BRUNO-BLANCH; ALAN TALEVI

Computer-aided identification of anticonvulsant effect of natural non-nutritive sweeteners Stevioside and Rebaudioside A

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES; Lugar: New York; Año: 2015 vol. 13 p. 313 - 318

MAURICIO E. DI IANNI; MELISA GANTNER; MARÍA E. RUIZ; EDUARDO A. CASTRO; LUIS E. BRUNO BLANCH; ALAN TALEVI

Systematic comparison of the performance of different 2D and 3D ligand-based virtual screening methodologies to discover anticonvulsant drugs

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING; Lugar: Oak Park; Año: 2015 vol. 18 p. 387 - 398

CAROLINA L. BELLERA; DARÍO E. BALCAZAR; MARÍA C. VANRELL ; FLORENCIA CASASSA; PABLO H. PALESTRO; LUCIANA GAVERNET; CARLOS A. LABRIOLA; JORGE GÁLVEZ; LUIS E. BRUNO-BLANCH; PATRICIA S. ROMANO; CAROLINA CARRILLO; ALAN TALEVI

Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2015 vol. 93 p. 338 - 348

ALAN TALEVI

Multi-target pharmacology: Possibilities and limitations of the ?skeleton key approach? from a medicinal chemist perspective

Frontiers in pharmacology; Lugar: Lausanne; Año: 2015 vol. 6 p. 1 - 7

CAROLINA L. BELLERA; MARÍA L. SBARAGLINI; DARÍO E. BALCAZAR; LAURA FRACCAROLI; MARÍA C. VANRELL; FLORENCIA CASASSA; CARLOS A. LABRIOLA; PATRICIA S. ROMANO; CAROLINA CARRILLO; ALAN TALEVI

High-throughput Drug Repositioning for the Discovery of New Treatments for Chagas Disease

MINI-REVIEWS IN MEDICINAL CHEMISTRY; Lugar: Oak Park; Año: 2015 vol. 15 p. 182 - 193

MAURICIO E. DI IANNI; ANDREA V. ENRIQUE; MARÍA ELENA DEL VALLE; BLANCA ALDANA ; MARÍA A. ROSELLA; LUISA L. ROCHA ARRIETA; EDUARDO A. CASTRO; LUIS E. BRUNO-BLANCH; ALAN TALEVI

Is there a relationship between sweet taste and seizures? Anticonvulsant and proconvulsant effects of non-nutritive sweeteners

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING; Lugar: Oak Park; Año: 2015 vol. 18 p. 335 - 345

MAURICIO E. DI IANNI; ALAN TALEVI

How Can Network-Pharmacology Contribute to Antiepileptic Drug Development?

Molecular and Cellular Epilepsy; Año: 2014 vol. 1 p. 21 - 28

CAROLINA L. BELLERA; DARÍO E. BALCAZAR; LUCAS N. ALBERCA; CARLOS A. LABRIOLA; ALAN TALEVI; CAROLINA CARRILLO

Identification of Levothyroxine Antichagasic Activity through Computer-Aided Drug Repurposing

SCIENTIFIC WORLD JOURNAL, THE; Lugar: New York; Año: 2014 vol. 2014 p. 1 - 9

MARÍA E. RUIZ; MELISA GANTNER; ALAN TALEVI

Applications of Nanosystems to Anticancer Drug Therapy (Part II. Dendrimers, Micelles, Lipid-based Nanosystems)

RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY; Lugar: Oak Park; Año: 2014 vol. 9 p. 99 - 128

ALAN TALEVI; MELISA GANTNER; MARÍA E. RUIZ

Applications of Nanosystems to Anticancer Drug Therapy (Part I. Nanogels, Nanospheres, Nanocapsules).

RECENT PATENTS ON ANTI-CANCER DRUG DISCOVERY; Lugar: Oak Park; Año: 2014 vol. 9 p. 83 - 98

CAROLINA L. BELLERA; DARÍO E. BALCAZAR; LUCAS N. ALBERCA; CARLOS A. LABRIOLA; ALAN TALEVI; CAROLINA CARRILLO

Application of computer-aided drug repurposing in the search of new cruzipain inhibitors: discovery of amiodarone and bromocriptine inhibitory effects

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Lugar: Washington; Año: 2013 vol. 53 p. 2402 - 2408

MELISA GANTNER; MAURICIO E. DI IANNI; MARÍA E. RUIZ; ALAN TALEVI; LUIS E. BRUNO-BLANCH

Development of Conformation Independent Computational Models for the Early Recognition of Breast Cancer Resistance Protein substrates

BIOMED RESEARCH INTERNATIONAL; Año: 2013 vol. 2013 p. 1 - 12

CAROLINA L. BELLERA; MELISA GANTNER; MARÍA E. RUIZ; ALAN TALEVI

Recent Advances on Nanotechnology Applications to Cancer Drug Therapy

Journal of Cancer Research Updates; Año: 2013

ALAN TALEVI, CAROLINA L. BELLERA, MAURICIO E. DI IANNI, PABLO R. DUCHOWICZ, LUIS E. BRUNO-BLANCH, EDUARDO A. CASTRO

An Integrated Drug Development Approach Applying Topological Descriptors

CURRENT COMPUTER-AIDED DRUG DESIGN; Lugar: Oak Park; Año: 2012 vol. 8 p. 172 - 181

ALAN TALEVI, CAROLINA L. BELLERA, MAURICIO E. DI IANNI, MELISA GANTNER, LUIS E. BRUNO-BLANCH, EDUARDO A. CASTRO

CNS drug development ? Lost in translation?

MINI-REVIEWS IN MEDICINAL CHEMISTRY; Año: 2012 vol. 12 p. 959 - 970

MARÍA E. RUIZ; ANABELLA GREGORINI; ALAN TALEVI; MARÍA G VOLONTÉ

Dissolution Studies of Generic Medications: New Evidence of Deviations from the Transitivity Principle

DISSOLUTION TECHNOLOGIES; Lugar: Hockessin, Delaware (USA); Año: 2012 vol. 19 p. 13 - 24

MAURICIO E. DI IANNI; ANDREA ENRIQUE; PABLO PALESTRO; LUCIANA GAVERNET; ALAN TALEVI; LUIS E. BRUNO BLANCH

Several new diverse anticonvulsant agents discovered in a virtual screening campaign aimed at novel antiepileptic drugs to treat refractory epilepsy

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Lugar: Washington; Año: 2012 p. 3325 - 3330

ALAN TALEVI, ANDREA V. ENRIQUE, LUIS E. BRUNO BLANCH

Anticonvulsant activity of artificial sweeteners: a structural link between sweettaste receptor T1R3 and brain glutamate receptors

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Lugar: Amsterdam; Año: 2012 vol. 22 p. 472 - 474

TALEVI ALAN; GOODARZI MOHAMMAD; ORTIZ ERLINDA V.; DUCHOWICZ PABLO R.; BELLERA CAROLINA L.; PESCE GUIDO; CASTRO EDUARDO A.; BRUNO-BLANCH LUIS E.

Prediction of drug intestinal absorption by new linear and non-linear QSPR

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Año: 2011 vol. 46 p. 218 - 228

CHIARA PIZZO; CECILIA SAIZ; ALAN TALEVI; LUCIANA GAVERNET; PABLO PALESTRO; CAROLINA BELLERA; LUIS BRUNO BLANCH; DIEGO BENÍTEZ; JUAN J. CAZZULO; AGUSTINA CHIDICHIMO; PETER WIPF; S. GRACIELA MAHLER

Synthesis of 2-Hydrazolyl-4-Thiazolidinones Based on Multicomponent Reactions and Biological Evaluation Against Trypanosoma Cruzi

CHEMICAL BIOLOGY & DRUG DESIGN; Año: 2011 vol. 77 p. 166 - 172

MAURICIO DI IANNI; ALAN TALEVI; EDUARDO A. CASTRO; LUIS E. BRUNO-BLANCH

Development of a highly specific ensemble of topological models for early identification of P-glycoprotein substrates

JOURNAL OF CHEMOMETRICS; Año: 2011 vol. 25 p. 313 - 322

ALAN TALEVI; CAROLINA L. BELLERA; EDUARDO A. CASTRO; LUIS E. BRUNO-BLANCH

Optimal Partition of Datasets of QSPR Studies: A Sampling Problem

MATCH-COMMUNICATIONS IN MATHEMATICAL AND IN COMPUTER CHEMISTRY; Año: 2010 vol. 63 p. 585 - 599

ALAN TALEVI

The New Patient and Responsible Self-Medication Practices: A Critical Review

Current Drug Safety; Año: 2010 vol. 5 p. 342 - 353

ALAN TALEVI; LUIS E. BRUNO BLANCH

Screening Virtual: una herramienta eficaz para el desarrollo de nuevos fármacos en Latinoamérica

ACTA FARM. BONAERENSE; Año: 2009 vol. 28 p. 141 - 150

ALAN TALEVI; LUCIANA GAVERNET; LUIS E. BRUNO-BLANCH

Combined Virtual Screening Strategies

Current Computer-Aided Drug Design; Año: 2009 vol. 5 p. 23 - 37

ALAN TALEVI; MARÍA E. RUIZ ; PAULA CONFORTI ; MARÍA G VOLONTÉ

Trabajo integrador experimental no estructurado: una experiencia pedagógica aplicada a la enseñanza de la asignatura Control de Calidad de Medicamentos

Anuario Lationoamericano de Educación en Química; Lugar: San Luis, Argentina; Año: 2009 vol. 24 p. 98 - 103

NOUNOU BÁRBARA; CATTÁNEO MARÍA E.; SALMÓN ROMINA; PALASEZZE LEONARDO; BOCCALERI JULIETA; CESTONA EUGENIA; BEDECARRÁS FLORENCIA; RANIERI FLORENCIA; TALEVI ALAN; SUSANA MUÑOZ

Estudio sobre el Consumo y la Auto-medicación con Antibióticos en la Ciudad de La Plata (Buenos Aires, Argentina)

ACTA FARM. BONAERENSE; Año: 2009 vol. 28 p. 544 - 551

LUCIANA GAVERNET; ALAN TALEVI; EDUARDO A. CASTRO; LUIS E. BRUNO-BLANCH

A Combined Virtual Screening 2D and 3D QSAR Methodology for the Selection of New Anticonvulsant Candidates from a Natural Product Library

QSAR & Combinatorial Science; Año: 2008 vol. 27 p. 1120 - 1129

PABLO R. DUCHOWICZ; ALAN TALEVI; LUIS E. BRUNO-BLANCH; EDUARDO CASTRO

New QSPR Study for the Prediction of Aqueous Solubility of Drug-Like Compounds

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2008 vol. 16 p. 7944 - 7955

PABLO R. DUCHOWICZ; ALAN TALEVI; LUIS E. BRUNO-BLANCH; EDUARDO A. CASTRO

Application of descriptors based on Lipinski?s rules in the QSPR study of aqueous solubilities

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2007 vol. 15 p. 3711 - 3719

ALAN TALEVI; CAROLINA L. BELLERA; EDUARDO A. CASTRO; LUIS E. BRUNO-BLANCH

A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN; Año: 2007 vol. 21 p. 527 - 538

ALAN TALEVI; MARIANA SELLA-CRAVERO; EDUARDO A. CASTRO; LUIS E. BRUNO-BLANCH

Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 2007 vol. 17 p. 1684 - 1690

ALAN TALEVI; JULIÁN J. PRIETO; LUIS E. BRUNO-BLANCH; EDUARDO A. CASTRO

New similarity-based algorithm and its application to classification of anticonvulsant compounds

JOURNAL OF ENZYME INHIBITION; Año: 2007 vol. 22 p. 253 - 265

ALAN TALEVI; EDUARDO A. CASTRO; LUIS E. BRUNO-BLANCH

New Solubility Models Based On Descriptors Derived From The Detour Matrix

Journal of the Argentine Chemical Society; Año: 2006 vol. 94 p. 129 - 141

CAROLINA L. BELLERA; ALAN TALEVI; LUIS E. BRUNO-BLANCH

Application of Linear Discriminant Analysis in the Search of Antiepileptogenic Drugs

ACTA FARM. BONAERENSE; Año: 2006 vol. 26 p. 244 - 252

JULIÁN J. PRIETO; ALAN TALEVI; LUIS E. BRUNO-BLANCH

Application of linear discriminant analysis in the virtual screening of antichagasic drugs through trypanothione reductase inhibition

MOLECULAR DIVERSITY; Año: 2006 vol. 10 p. 361 - 375