INVESTIGADORES
GOLDBAUM Fernando Alberto
artículos
SRINIVASAN L, ALZOGARAY V, SELVAKUMAR D, NATHAN S, YODER JB, WRIGHT KM, KLINKE S, NWAFOR JN, LABANDA MS, GOLDBAUM FA, SCHÖN A, FREIRE E, TOMASELLI GF, AMZEL LM, BEN-JOHNY M, GABELLI SB
Development of high-affinity nanobodies specific for NaV1.4 and NaV1.5 voltage-gated sodium channel isoforms
JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2022
MORAN MC, DOMINGUEZ MP, BENCE AR, RODRIGUEZ MG, GOLDBAUM FA, ZYLBERMAN V, PAOLA PR, LUPI G, MARCIPAR IS, LÜTZELSCHWAB CM, ESTEIN SM
Evaluation of the efficacy of polymeric antigen BLSOmp31 formulated in a new cage-like particle adjuvant (ISPA) administered by parenteral or mucosal routes against Brucella ovis in BALB/c mice
RESEARCH IN VETERINARY SCIENCE; Lugar: Amsterdam; Año: 2022
SALINAS F, MARELLI BE, SANGUINETI S, GOLDBAUM F, MUÑOZ L, ETCHEVERS L, SILVESTRINI P, NOTARO US, SALVETTI NR, ZYLBERMAN V, ORTEGA HH
Non-clinical safety assessment and in vivo biodistribution of CoviFab, an RBD-specific F(ab')2 fragment derived from equine polyclonal antibodies
Toxicol. Appl. Pharmacol.; Lugar: New York; Año: 2022
LOPARDO G, BELLOSO WH, NANNINI E, COLONNA M, SANGUINETI S, ZYLBERMAN V, PEREIRO A, SUED O, CAHN P, SPATZ S AND GOLDBAUM FA
RBD-specific polyclonal F(ab´)2 fragments of equine antibodies in patients with moderate to severe COVID-19 disease: a randomized, multicentre, double-blind, placebo-controlled, adaptive phase 2/3 clinical trial
EClinical Medicine; Lugar: Londres; Año: 2021
JIMENA RINALDI, IGNACIO FERNÁNDEZ, HEEWHAN SHIN, GABRIELA SYCZ, SEMINI GUNAWARDANA, INDIKA KUMARAPPERUMA, JUAN M. PAZ, LISANDRO H. OTERO, MARÍA L. CERUTTI, ÁNGELES ZORREGUIETA, ZHONG REN, SEBASTIÁN KLINKE, XIAOJING YANG AND FERNANDO A. GOLDBAUM
Dimer asymmetry and light activation mechanism in Brucella blue-light sensor histidine kinase
mBio; Año: 2021
FARIAS A, SOTO A, PUTTUR F, GOLDIN CJ, SOSA S, GIL C, GOLDBAUM FA AND BERGUER PM
A TLR4 agonist improves immune checkpoint blockade treatment by increasing the ratio of effector to regulatory cells within the tumor microenvironment
Scientific Reports; Lugar: Londres; Año: 2021 vol. 11
CONFORTE V, OTERO LH, TOUM L, SIRIGU S, ANTELO GT, RINALDI J, FOSCALDI S, KLINKE S, CHAVAS LMG, VOJNOV AA, GOLDBAUM FA, MALAMUD F, BONOMI HR
Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms
FEBS JOURNAL; Lugar: Londres; Año: 2021 vol. 288 p. 5986 - 6002
MORAN MC, BENCE AR, VALLECILLO MFS, LÜTZELSCHWAB CM, RODRIGUEZ MG, PARDO R, GOLDBAUM FA, ZYLBERMAN V, PALMA SD, MALETTO BA, ESTEIN SM
Polymeric antigen BLSOmp31 formulated with class B CpG-ODN in a nanostructure (BLSOmp31/CpG-ODN/Coa-ASC16) administered by parenteral or mucosal routes confers protection against Brucella ovis in Balb/c mice
Research in Veterinary Science; Lugar: New York; Año: 2021 vol. 135 p. 217 - 227
OTERO LH, FOSCALDI S, ANTELO GT, ROSANO GL, SIRIGU S, KLINKE S, DEFELIPE LA, SÁNCHEZ-LAMAS M, BATTOCCHIO G, CONFORTE V, VOJNOV AA, CHAVAS LMG, GOLDBAUM FA, MROGINSKI MA, RINALDI J, BONOMI HR
Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level
Science Advances; Lugar: New York; Año: 2021
PELLIZZA L, LÓPEZ JL, VÁZQUEZ S, SYCZ G, GUIMARÃES BG, RINALDI J, GOLDBAUM FA, ARAN M, MAC CORMACK WP AND KLINKE S
Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic bacterium Bizionia argentinensis JUB59
JOURNAL OF STRUCTURAL BIOLOGY; Año: 2020
ANTELO GT, SÁNCHEZ-LAMAS M, GOLDBAUM FA, OTERO LH, BONOMI HR, RINALDI J
A Spectroscopy-based Methodology for Rapid Screening and Characterization of Phytochrome Photochemistry in Search of Pfr-favoured Variants
PHOTOCHEMISTRY AND PHOTOBIOLOGY; Año: 2020
ZYLBERMAN V, SANGUINETI S, PONTORIERO AV, HIGA SV, CERUTTI ML, LAUCHÉ C, LÓPEZ JC, SEIGELCHIFER M, SOSA S, VILARIÑO C, LÓPEZ BISCAYART P, CORLEY E, SPATZ L, BAUMEISTER EG AND GOLDBAUM FA
Development of a Hyperinmune equine serum therapy for COVID-19 in Argentina
MEDICINA (BUENOS AIRES); Año: 2020 vol. 80 p. 1 - 6
MELLI L, ZYLBERMAN V, HIRIART Y, LAUCHE C, BASCHKIER A, PARDO R, MILIWEBSKY E, CHINEN I, RIVAS M, GOLDBAUM FA, UGALDE J, COMERCI D AND CIOCCHINI A.
Development and evaluation of a novel VHH-based immunocapture assay for high sensitivity detection of Shiga toxin type 2 (Stx2) in stool samples
JOURNAL OF CLINICAL MICROBIOLOGY; Año: 2020
CAGNONI AJ, PRIMO ED, KLINKE S, CANO ME, GIORDANO W, MARIÑO KV, KOVENSKY J, GOLDBAUM FA, UHRIG ML, OTERO LH
Effect of UVB solar irradiation on Laccase enzyme: evaluation of the photooxidation process and its impact over the enzymatic activity for pollutants bioremediation
AMINO ACIDS; Lugar: Berlin; Año: 2020 vol. 52 p. 925 - 939
TORRES NI, REGGE MV, LAUCHE C, PARDO R, DOMAICA CI, FUERTES MB, MADAUSS KP, HANCE KW, GLOGER I, ZYLBERMAN V, GOLDBAUM FA AND ZWIRNER NW
Restoration of anti-tumor immunity through anti-MICA antibodies elicited with a chimeric protein
Journal for ImmunoTherapy of Cancer; Lugar: Londres; Año: 2020
CAGNONI AJ, PRIMO ED, KLINKE S, CANO ME, GIORDANO W, MARIÑO KV, KOVENSKY J, GOLDBAUM FA, UHRIG ML, OTERO LH
Crystal structures of peanut lectin in the presence of synthetic β-N- and β-S-galactosides disclose evidence for the recognition of different glycomimetic ligands
Acta Crystallogr D Struct Biol; Año: 2020 vol. 1 p. 1080 - 1091
ALZOGARAY V, URRUTIA M, BERGUER P, ROSSI A, ZYLBERMAN V, PARDO R, BONOMI HR AND GOLDBAUM FA
Characterization of folding-sensitive nanobodies as tools to study the expression and quality of protein particle immunogens
JOURNAL OF BIOTECHNOLOGY; Lugar: Amsterdam; Año: 2019 vol. 293 p. 17 - 23
KLINKE S, RINALDI J, GOLDBAUM FA, SUAREZ S AND OTERO LH
An All-Inclusive and Straightway Laboratory Activity to Solve the Three-Dimensional Crystal Structure of a Protein
BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION; Lugar: Bethesda; Año: 2019
DÍAZ AG, QUINTEROS DA, PAOLICCHI FA, RIVERO MA, PALMA SD, PARDO RP, CLAUSSE M, ZYLBERMAN V, GOLDBAUM FA AND ESTEIN SM
Mucosal immunization with polymeric antigen BLSOmp31 using alternative delivery systems against Brucella ovis in rams
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; Lugar: Amsterdam; Año: 2019 vol. 209 p. 70 - 77
SOSA S, ROSSI AH, SZALAI AM, KLINKE S, RINALDI J, FARIAS A, BERGUER PM, NADRA AD, STEFANI FD, GOLDBAUM FA AND BONOMI HR
Asymmetric bifunctional protein nanoparticles through redesign of self-assembly
Nanoscale Advances; Lugar: Londres; Año: 2019 vol. 1 p. 1833 - 1846
SERER MI, CARRICA MDC, TRAPPE J, LÓPEZ ROMERO S, BONOMI HR, KLINKE S, CERUTTI ML AND GOLDBAUM FA
A high-throughput screening for inhibitors of riboflavin synthase identifies novel antimicrobial compounds to treat brucellosis
FEBS JOURNAL; Año: 2019
SAPP, AMANDA; HUGUET-TAPIA, JOSÉ C.; SÁNCHEZ-LAMAS, MAXIMILIANO; ANTELO, GIULIANO T.; PRIMO, EMILIANO D.; RINALDI, JIMENA; KLINKE, SEBASTIÁN; GOLDBAUM, FERNANDO A.; BONOMI, HERNÁN R.; CHRISTNER, BRENT C.; OTEROC, LISANDRO H.
Draft genome sequence of Methylobacterium sp. strain V23, isolated from accretion ice of the Antarctic subglacial Lake Vostok
Genome Announcements; Año: 2018 vol. 6
FERNÁNDEZ, IGNACIO; SYCZ, GABRIELA; GOLDBAUM, FERNANDO ALBERTO; DEL CARMEN CARRICA, MARIELA
Acidic pH triggers the phosphorylation of the response regulator NtrX in alphaproteobacteria
PLOS ONE; Año: 2018 vol. 13
PILLAI G, CHIBALE K, CONSTABLE EC, KELLER AN, GUTIERREZ MM, MIRZA F, SENGSTAG C, MASIMIREMBWA C, DENTI P, MAARTENS G, RAMSAY M, OGUTU B, MAKONNEN E, GORDON R, FERREIRA CG, GOLDBAUM FA, DEGRAVE WMS, SPECTOR J, TADMOR B AND KAISER HJ
The Next Generation Scientist program: capacity-building for future scientific leaders in low- and middle-income countries
Bmc med educ; Lugar: Bethesda; Año: 2018 vol. 18
RINALDI J, FERNÁNDEZ I, POTH LM, SHEPARD WE, SAVKO M, GOLDBAUM FA AND KLINKE S.
Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state
Biochem Biophys Rep; Lugar: Bethesda; Año: 2018 vol. 16 p. 39 - 43
HIRIART Y, PARDO R, BUKATA L, LAUCHÉ C, MUÑOZ L, COLONNA M, GOLDBAUM FA, SANGUINETI S, ZYLBERMAN V.
Development of a anti-Shiga toxin product for prevention of the hemolytic uremic syndrome
MEDICINA (BUENOS AIRES); Año: 2018 vol. 78 p. 107 - 112
FUMEY, WILLIAM; KOENIGSDORF, JULIA; KUNICK, VALENTIN; MENZEL, STEPHAN; SCHÜTZE, KERSTIN; UNGER, MANDY; SCHRIEWER, LEVIN; HAAG, FRIEDRICH; ADAM, GERHARD; OBERLE, ANNA; BINDER, MASCHA; FLIEGERT, RALF; GUSE, ANDREAS; ZHAO, YONG JUAN; LEE, HON CHEUNG; MALAVASI, FABIO; GOLDBAUM, FERNANDO; VAN HEGELSOM, ROB; STORTELERS, CATELIJNE; BANNAS, PETER; KOCH-NOLTE, FRIEDRICH
Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivo
Scientific Reports; Lugar: Londres; Año: 2017 vol. 7
BALCAZAR DE, VANRELL MC, ROMANO PS, PEREIRA CA, GOLDBAUM FA, BONOMI HR AND CARRILLO C
The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists
PLOS NEGLECTED TROPICAL DISEASES; Lugar: San Francisco; Año: 2017 vol. 11
CERUTTI ML, OTERO LH, SMAL C, PELLIZA L, GOLDBAUM FA, KLINKE S AND ARAN M
Structural and functional characterization of a cold adapted TPM-domain with ATPase/ADPase activity
JOURNAL OF STRUCTURAL BIOLOGY; Año: 2017 vol. 197 p. 201 - 209
CLAUSSE M, DÍAZ AG, PARDO RM, ZYLBERMAN V, GOLDBAUMFA AND ESTEIN SM
Polymeric antigen BLSOmp31 in aluminium hydroxide induces serum bactericidal and opsonic antibodies against Brucella canis in dogs.
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; Lugar: Amsterdam; Año: 2017 vol. 184 p. 36 - 41
FERNÁNDEZ I, CORNACIU I, CARRICA MC, UCHIKAWA E, HOFFMANN G, SIEIRA R, MÁRQUEZ JA AND GOLDBAUM FA
Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators
JOURNAL OF MOLECULAR BIOLOGY; Lugar: Manchester; Año: 2017 vol. 429 p. 1192 - 1212
HIRIART Y, ROSSI AH, BIEDMA ME, ERREA AJ, MORENO G, CAYET D, RINALDI J, BLANCÁ B, SIRARD JC, GOLDBAUM FA, BERGUER P AND RUMBO M
Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella
PROTEIN SCIENCE; Año: 2017 vol. 26 p. 1049 - 1059
MEJIAS M, HIRIART Y, LAUCHÉ C, FERNANDEZ-BRANDO RJ, PARDO R, BRUBALLA A, RAMOS MV, GOLDBAUM FA, PALERMO M AND ZYLBERMAN V.
Development of camelid single chain antibodies against Shiga toxin type 2 with therapeutic potential against Hemolytic Uremic Syndrome
Scientific Reports; Lugar: New York; Año: 2016
RINALDI J, ARRAR M, SYCZ G, CERUTTI ML, BERGUER PM, PARIS G, ESTRÍN DA, MARTÍ MA, KLINKE S, GOLDBAUM FA.
Structural Insights into the HWE Histidine Kinase Family: The Brucella Blue Light-Activated Histidine Kinase Domain
JOURNAL OF MOLECULAR BIOLOGY; Lugar: Manchester; Año: 2016 p. 1165 - 1179
BONOMI HR, TOUM L, TOSCANI AM, GUDESBLAT GE, LESKOW FC, GOLDBAUM FA, VOJNOV AA, MALAMUD F
Xanthomonas campestris attenuates virulence by sensing light through a bacteriophytochrome photoreceptor
EMBO REPORTS; Año: 2016
DÍAZ AG, QUINTEROS DA, GUTIÉRREZ SE, RIVERO MA, PALMA SD, ALLEMANDI DA, PARDO RP, ZYLBERMAN V, GOLDBAUM FA AND ESTEIN SM
Immune response induced by conjunctival immunization with polymeric antigen BLSOmp31 using a thermoresponsive and mucoadhesive in situ gel as vaccine delivery system for prevention of ovine brucellosis
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; Lugar: Amsterdam; Año: 2016 vol. 178 p. 50 - 56
DÍAZ AG, QUINTEROS DA, LLABOT JM, PALMA SD, ALLEMANDI DA, GHERSI G, ZYLBERMAN V, GOLDBAUM FA, ESTEIN SM
Spray dried microspheres based on chitosan: A promising new carrier for intranasal administration of polymeric antigen BLSOmp31 for prevention of ovine brucellosis
MATERIALS SCIENCE & ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS; Lugar: Amsterdam; Año: 2016 vol. 62 p. 489 - 496
OTERO LH, KLINKE S, RINALDI J, VELÁZQUEZ-ESCOBAR F, MROGINSKI MA, LÓPEZ MF; MALAMUD F, VOJNOV AA, HILDEBRANDT P, GOLDBAUM FA, BONOMI HR.
Structure of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris: clues on its long-range signaling mechanism
JOURNAL OF MOLECULAR BIOLOGY; Lugar: Manchester; Año: 2016
IBAÑEZ AE, CORIA LM, CARABAJAL MV, DELPINO MV, RISSO GS, COBIELLO PG, RINALDI J, BARRIONUEVO P, BRUNO L, FRANK F, KLINKE S, GOLDBAUM FA, BRIONES G, GIAMBARTOLOMEI GH, PASQUEVICH KA, CASSATARO J
A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggering specific mucosal immune responses
JOURNAL OF CONTROLLED RELEASE; Lugar: Amsterdam; Año: 2015 vol. oct p. 18 - 28
SYCZ G, CARRICA MC, TSENG TS, BOGOMOLNI RA, BRIGGS WR, GOLDBAUM FAAND PARIS G
LOV histidine kinase modulates the General Stress Response system and affects the virB operon expression in Brucella abortus
PLOS ONE; Lugar: San Francisco; Año: 2015
ALFANO EF, LENTZ EM, BELLIDO D, DUS SANTOS MJ, GOLDBAUM FA, WIGDOROVITZ A, BRAVO-ALMONACID FF
Expression of the Multimeric and Highly Immunogenic Brucella spp. Lumazine Synthase Fused to Bovine Rotavirus VP8d as a Scaffold for Antigen Production in Tobacco Chloroplasts
Frontiers in Plant Science; Lugar: Lausanne; Año: 2015 vol. 6
UNGER M, EICHHOFF AM, SCHUMACHER L, STRYSIO M, MENZEL S, SCHWAN C, ALZOGARAY V, ZYLBERMAN V, SEMAN M, BRANDNER J, ROHDE H, ZHU K, HAAG F, MITTRÜCKER HW, GOLDBAUM FA, AKTORIES K AND KOCH-NOLTE F
Selection of Nanobodies that Block the Enzymatic and Cytotoxic Activities of the Binary Clostridium Difficile Toxin CDT
Scientific Reports; Lugar: New York; Año: 2015 vol. 5
ROSSI AH, FARIAS A, FERNÁNDEZ JE, BONOMI HR, GOLDBAUM FA, BERGUER PM
Brucella spp. Lumazine Synthase induces a TLR4-mediated protective response against B16 melanoma in mice
PLOS ONE; Lugar: San Francisco; Año: 2015
GUTIÉRREZ-PRECIADO A, TORRES AG, MERINO E, BONOMI HR, GOLDBAUM FA AND GARCÍA-ANGULO VA
Extensive identification of bacterial riboflavin transporters and their distribution across bacterial species
PLOS ONE; Lugar: San Francisco; Año: 2015
KLINKE S, FOOS N, RINALDI JJ, PARIS G, GOLDBAUM FA, LEGRAND P, GUIMARAES BG AND THOMPSON A
S-SAD phasing of monoclinic histidine kinase from Brucella abortus combining data from multiple crystals and orientations: an example of data collection strategy and a posteriori analysis of different data combinations
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY; Lugar: Londres; Año: 2015
FERNÁNDEZ I, OTERO LH, KLINKE S, CARRICA MC AND GOLDBAUM FA
Snapshots of conformational changes of NtrX receiver domain shed light into its signal transduction mechanism
JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2015 vol. 47 p. 3258 - 3272
MEJIAS MP, CABRERA G, FERNÁNDEZ-BRANDO RJ, BASCHKIER A, GHERSI G, ABREY-RECALDE MJ, MILIWEBSKY E, MEISS R, GOLDBAUM FA, ZYLBERMAN V, RIVAS M, PALERMO MS
Protection of mice against Stx2-associated damage by maternal immunization with BLS-Stx2B chimera
INFECTION AND IMMUNITY; Lugar: Washington; Año: 2014 vol. 82 p. 1491 - 1499
ARAN M, SMAL C, PELLIZZA L, GALLO M, OTERO LH, KLINKE S, GOLDBAUM FA, ITHURRALDE ER, BERCOVICH A, MAC CORMACK WP, TURJANSKI AG, CICERO DO
Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand-alone TPM domain
PROTEINS: STRUCTURE, FUNCTION AND GENETICS; Lugar: New York; Año: 2014 vol. 82 p. 3062 - 3078
KLINKE S, OTERO LH, RINALDI S, SOSA S, GUIMARÃES BG, SHEPARD WE, GOLDBAUM FA AND BONOMI HR
Crystallization and preliminary X-ray characterization of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris pv. Campestris
ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS; Lugar: Londres; Año: 2014 vol. 70 p. 1636 - 1639
SERER MI, BONOMI HR, GOMES GUIMARAES B, ROSSI RC, GOLDBAUM FA AND KLINKE S
Crystallographic and kinetic study on riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY; Lugar: Londres; Año: 2014 vol. 70 p. 1419 - 1434
ALVAREZ P, ZYLBERMAN V, GHERSI G, BOADO L, GOLDBAUM FA AND MATTION N.
Tandem repeats of the extracellular domain of Matrix 2 influenza protein exposed in Brucella lumazine synthase decameric carrier molecule induce protection in mice
VACCINE; Lugar: Amsterdam; Año: 2013 vol. 31 p. 806 - 812
DÍAZ AG, CLAUSSE M, PAOLICCHI FA, FIORENTINO MA, GHERSI G, ZYLBERMAN V, GOLDBAUM FA AND ESTEIN SM.
Immune response and serum bactericidal activity against Brucella ovis elicited using a short immunization schedule with the polymeric antigen BLSOmp31 in rams
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; Lugar: Amsterdam; Año: 2013 vol. 154 p. 36 - 41
GARCÍA ANGULO VA, BONOMI HR, POSADAS DM, SERER MI, TORRES AG, ZORREGUIETA A AND GOLDBAUM FA
Identification of a novel family of functional bacterial flavin transporters in Rhizobium leguminosarum
JOURNAL OF BACTERIOLOGY; Lugar: Washington; Año: 2013 vol. 195 p. 4611 - 4619
CARRICA MC, FERNANDEZ I, SIEIRA R, PARIS G AND GOLDBAUM FA.
The two-component systems PrrBA and NtrYX coordinately regulate the adaptation of Brucella abortus to an oxygen-limited environment
MOLECULAR MICROBIOLOGY; Año: 2013 vol. 88 p. 822 - 833
CLAUSSE M, DÍAZ AG, GHERSI G, ZYLBERMAN V, CASSATARO J, GIAMBARTOLOMEI GG, GOLDBAUM FA AND ESTEIN SM
The vaccine candidate BLSOmp31 protects mice against Brucella canis infection
VACCINE; Lugar: Amsterdam; Año: 2013 vol. 31 p. 6129 - 6135
MENZEL S, RISSIEK B, HAAG F, GOLDBAUM F AND KOCH-NOLTE F.
The art of blocking ARTs: Nanobodies as experimental and therapeutic tools to block mammalian and toxin ADP-ribosyltransferases
FEBS JOURNAL; Año: 2013 vol. 15 p. 3543 - 3550
MEJIAS MP, GHERSI G, CRAIG PO, PANEK CO, BENTANCOR LV, GOLDBAUM FA, ZYLBERMAN V AND PALERMO MS
Immunization with a chimera between the B subunit of Shiga toxin type 2 and Brucella lumazine synthase confers total protection against Shiga toxins
JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2013 vol. 191 p. 2403 - 2411
RINALDI J,GALLO M, KLINKE S, PARIS G, BONOMI H, BOGOMOLNI RA, CICERO D, GOLDBAUM FA
The beta-Scaffold of the LOV Domain of the Brucella Light-Activated Histidine Kinase Is a Key Element for Signal Transduction
JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2012 vol. 420 p. 112 - 127
CRAIG PO, ALZOGARAY V AND GOLDBAUM FA
Polymeric Display of Proteins through High Affinity Leucine Zipper Peptide Adaptors
BIOMACROMOLECULES; Lugar: Washington; Año: 2012 vol. 13 p. 1112 - 1121
BONOMI H, POSADAS D, PARIS G, FREDERICKSON M, PIETRASANTA L., BOGOMOLNI R, ZORREGUIETA A AND GOLDBAUM FA
Light regulates attachment, EPS production and nodulation in Rhizobium leguminosarum through LOV-histidine kinase photoreceptor
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2012 vol. 109 p. 12135 - 12140
CARRICA M, FERNANDEZ I, MARTI M, PARIS G AND GOLDBAUM FA
The NtrY/X two-component system of Brucella spp. acts as a redox sensor and regulates the expression of nitrogen respiration enzymes
MOLECULAR MICROBIOLOGY; Lugar: Londres; Año: 2012 vol. 85 p. 39 - 50
BERGUER PM, ALZOGARAY VA, ROSSI AH, MUNDIÑANO J, PIAZZON I AND GOLDBAUM FA.
A polymeric protein induces specific cytotoxicity in a TLR4 dependent manner in the absence of adjuvants
PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 45705 - 45706
BELLIDO D, CHACANA P, MOZGOVOJ M, GONZALEZ D, GOLDBAUM FA, WIGDOROVITZ A AND DUS SANTOS MJ
Brucella spp. Lumazine synthase as a novel immunomodulator to produce egg yolk antibodies
Advances in Biosciences and Biotechnology; Lugar: Irvine; Año: 2012 vol. 3 p. 80 - 86
CARRICA MC, CRAIG PO, GARCIA-ANGULO VA, AGUIRRE A, GARCIA-VESCOVI E, GOLDBAUM FA, CRAVERO SL
YqiC of Salmonella enterica serovar Typhimurium is a membrane fusogenic protein required for mice colonization
BMC MICROBIOLOGY; Lugar: Londres; Año: 2011 vol. 11 p. 95 - 95
VANINA ALZOGARAY, WELBECK DANQUAH, ANDRE´S AGUIRRE, MARIELA URRUTIA, PAULA BERGUER, ELEONORA GARCÍA VE´SCOVI, FRIEDRICH HAAG, FRIEDRICH KOCH-NOLTE, AND FERNANDO A. GOLDBAUM
Single domain llama antibodies as specific intracellular inhibitors of SpvB, the actin ADP-ribosylating toxin of Salmonella typhimurium
FASEB JOURNAL; Lugar: Bethesda; Año: 2011 vol. 25 p. 526 - 534
AINCIART N, ZYLBERMAN V, CRAIG P, NYGAARD D, BONOMI H, CAUERHFF A. AND GOLDBAUM FA
Sensing the dissociation of a polymeric enzyme by means of an engineered intrinsic probe
PROTEINS: STRUCTURE, FUNCTION AND GENETICS; Lugar: New York; Año: 2011 vol. 79 p. 1079 - 1088
FRAGOSO G, ESQUIVEL-GUADARRAMA F, SANTANA MA, BOBES RJ, HERNÁNDEZ B, CERVANTES J, SEGURA R, GOLDBAUM FA, SCIUTTO E, ROSAS G
Heterologous prime-boost oral immunization with GK-1 peptide from Taenia crassiceps cysticerci induces protective immunity
CLINICAL AND VACCINE IMMUNOLOGY; Lugar: Washington; Año: 2011 vol. 18 p. 1067 - 1076
DOÑA V, URRUTIA M, BAYARDO M, ALZOGARAY V, GOLDBAUM FA, CHIRDO F. J.
Single domain antibodies are specially suited for quantitative determination of gliadins in denaturing conditions
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY; Año: 2010 vol. 58 p. 918 - 926
BONOMI H, MARCHESINI MI, KLINKE S, UGALDE S, ZYLBERMAN V, UGALDE R, COMERCI D AND GOLDBAUM FA.
Atypical Riboflavin Pathway is Essential for Brucella abortus Virulence
PLOS ONE; Año: 2010 vol. 5 p. 9435 - 9435
BELLIDO, D., CRAIG, P. O., MOZGOVOJ, M. V., GONZALEZ, D. D., WIGDOROVITZ, A., GOLDBAUM, F. A. AND DUS SANTOS, M. J.
Brucella spp. lumazine synthase as a Bovine Rotavirus antigen delivery system
VACCINE; Año: 2009 vol. 27 p. 136 - 145
ESTEIN SM, FIORENTINO MA, PAOLICCHI FA, CLAUSSE M, MANAZZA J, CASSATARO J, GIAMBARTOLOMEI GH, CORIA LM, ZYLBERMAN V, FOSSATI CA, KJEKEN R, GOLDBAUM FA.
The polymeric antigen BLSOmp31 confers protection against Brucella ovis infection in rams
VACCINE; Año: 2009 vol. 27 p. 5704 - 6711
WESOLOWSKI J, ALZOGARAY V, REYELT J, UNGER M, JUAREZ K, URRUTIA M, CAUERHFF A, DANQUAH W, RISSIEK B, SCHEUPLEIN F, SCHWARZ N, ADRIOUCH S, BOYER O, SEMAN M, LICEA A, SERREZE DV, GOLDBAUM FA, HAAG F, KOCH-NOLTE F.
Single domain antibodies: promising experimental and therapeutic tools in infection and immunity
MEDICAL MICROBIOLOGY AND IMMUNOLOGY; Año: 2009 vol. 198 p. 157 - 174
CARRICA, M. C., CRAIG, P. O., ALONSO, S., GOLDBAUM, F. A. AND CRAVERO, S. L.
Brucella abortus MFP: a trimeric coiled-coil protein with membrane fusogenic activity
BIOCHEMISTRY; Año: 2008 vol. 47 p. 8165 - 8175
PRIMO, M. E., KLINKE, S., SICA, M. P., GOLDBAUM, F. A., JAKONCIC, J., POSKUS, E. AND ERMÁCORA, M. R.
Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2008 vol. 238 p. 4674 - 4681
RATIER, L., URRUTIA, M., PARIS, G., ZAREBSKI, L., FRASCH, A. C. AND GOLDBAUM, F. A.
Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies
PLOS ONE; Año: 2008 vol. 3 p. 3524 - 3525
SWARTZ, T. E., TSENG, T.-S., FREDERICKSON, M. A., PARIS, G., COMERCI, D. J., RAJASHEKARA, G., KIM, J.-G., MUDGETT, M. B., SPLITTER, G. A., UGALDE, R. A., GOLDBAUM, F. A., BRIGGS, W. R. AND BOGOMOLNI, R. A.
Blue-light-activated Histidine kinases function as two-component sensors in bacteria
SCIENCE; Año: 2007 vol. 317 p. 1090 - 1093
KLINKE, S., ZYLBERMAN, V., BONOMI, H. R., HAASE, I., GUIMARÃES, B. G., BRADEN, B. C., BACHER, A., FISCHER, M. AND GOLDBAUM, F. A.
Structural and kinetic properties of Lumazine synthase isoenzymes in the order Rhizobiales
JOURNAL OF MOLECULAR BIOLOGY; Año: 2007 vol. 373 p. 664 - 680
ACIERNO, J. P., BRADEN, B. C., KLINKE, S., GOLDBAUM, F. A. AND CAUERHFF, A.
Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies
JOURNAL OF MOLECULAR BIOLOGY; Año: 2007 vol. 374 p. 130 - 146
CASSATARO, J., PASQUEVICH, K. A., ESTEIN, S. M. , LAPLAGNE, D., VELIKOVSKY, C. A., DE LA BARRERA, S., BOWDEN, R. A., FOSSATI, C. A., GIAMBARTOLOMEI, G. H. AND GOLDBAUM, F. A.
A DNA vaccine coding for the quimera BLSOmp31 induced a better degree of protection against B. ovis and a similar degree of protection against B. melitensis than Rev.1 vaccination
VACCINE; Año: 2007 vol. 25 p. 5958 - 5967
CASSATARO, J., PASQUEVICH, K. A., ESTEIN, S. M. , LAPLAGNE, D., VELIKOVSKY, C. A., DE LA BARRERA, S., BOWDEN, R. A., FOSSATI, C. A., GIAMBARTOLOMEI, G. H. AND GOLDBAUM, F. A.
A recombinant subunit vaccine based on the insertion of 27 aminoacids from Omp31 to the N-terminus of BLS induced a similar degree of protection against B. ovis than Rev-1 vaccination
VACCINE; Año: 2007 vol. 25 p. 4437 - 4446
SCIUTTO, E., ROSAS, G., CRUZ-REVILLA, C., TOLEDO, A., CERVANTES, J., HERNÁNDEZ, M., HERNÁNDEZ, B., GOLDBAUM, F. A., DE ALUJA, A. S., FRAGOSO, G. AND LARRALDE, C.
Renewed hope for a vaccine against the intestinal adult Taenia solium
JOURNAL OF PARASITOLOGY; Año: 2007 vol. 93 p. 824 - 831
E. SCIUTTO, G. ROSAS, M. HERNANDEZ, C. CRUZ, A. TOLEDO, A. BLANCAS, G. ACERO, B. HERNANDEZ, J. CERVANTES, R. BOBES, F. A. GOLDBAUM, M. HUERTA, A. DIAZ-OREA, A. FLEURY, A. ALUJA, J. CABRERA, L. HERRERA-ESTRELLA, G. FRAGOSO, C. LARRALDE.
Improvement of the synthetic tri-peptide vaccine (S3Pvac) against porcine Taenia solium cysticercosis in search of a more effective, inexpensive and manageable vaccine
VACCINE; Año: 2007 vol. 25 p. 1368 - 1378
KOCH-NOLTE, F., REYELT, J., SCHÖßOW, B., SCHWARZ, N., SCHEUPLEIN, F., ROTHENBURG, S., HAAG, F., ALZOGARAY, V., CAUERHFF, A. AND GOLDBAUM, F. A.
Single domain antibodies from llama effectively and specifically block T cell ecto-ADP-ribosyltransferase ART2.2 in vivo
FASEB JOURNAL; Año: 2007 vol. 21 p. 3490 - 3498
SANGUINETI, S., CROWLEY, J.M.C., MERLO, M.F.L., CERUTTI, M.L., WILSON, I.A., GOLDBAUM, F.A., STANFIELD, R. & DE PRAT-GAY, G.
Specific Recognition of a DNA Immunogen by its Elicited Antibody
JOURNAL OF MOLECULAR BIOLOGY; Año: 2007 vol. 370 p. 183 - 195
GOMEZ, G., CAUERHFF, A., CRAIG, P., GOLDBAUM, F. A. AND DELFINO, J. M.
Exploring protein interfaces with a general photochemical reagent
PROTEIN SCIENCE; Año: 2006 vol. 15 p. 744 - 752
DELPINO, M. V., CASSATARO, J., FOSSATI, C. A., GOLDBAUM, F. A., AND BALDI, P. C.
Brucella outer membrane protein Omp31 is a haemin-binding protein
MICROBES AND INFECTION; Año: 2006 vol. 8 p. 1203 - 1208
ROSAS, G., FRAGOSO, G., AINCIART, N., BERGER, P., TOLEDO, A., CRUZ, C., MENESES, G., ESQUIVEL, F., SANTANA, A., BOBES, R., GOLDBAUM, F. A., SCIUTTO, E.
Brucella spp. lumazine synthase : A novel adjuvant and antigen delivery system to effectively induced oral immunity
MICROBES AND INFECTION; Año: 2006 vol. 8 p. 1277 - 1286
BERGUER, P. M., MUNDIÑANO, J., PIAZZON, I. AND GOLDBAUM, F. A.
A Polymeric Bacterial Protein Activates Dendritic Cells Via TLR4
JOURNAL OF IMMUNOLOGY; Año: 2006 vol. 176 p. 2366 - 2372
CRUZ-REVILLA, C., TOLEDO, A., ROSAS, G., HUERTA, M., FLORES-PEREZ, I., PEÑA, N., MORALES, J., CISNEROS-QUIÑONES, J., MENESES, G., DÍAZ-OREA, A., ANCIART, N., GOLDBAUM, F. A., ALUJA, A., LARRALDE, C., FRAGOSO, G. AND SCIUTTO, E.
Effective protection against experimental Taenia solium tapeworm infection in hamsters by primo-infection and by vaccination with recombinant or synthetic heterologous antigens
JOURNAL OF PARASITOLOGY; Año: 2006 vol. 92 p. 864 - 867
M. L. CERUTTI, D. U. FERREIRO, S. SANGUINETI, F. A. GOLDBAUM* AND GONZALO DE PRAT-GAY.
Antibody recognition of a flexible epitope at the DNA binding site of the human papillomavirus transcriptional regulator E2
BIOCHEMISTRY; Año: 2006 vol. 45 p. 15520 - 15528
ZYLBERMAN1, V., KLINKE, S., HAASE, I., BACHER, A., FISCHER, M. AND GOLDBAUM, F. A.
Evolution of Vitamin B2 biosynthesis. 6,7-dimethyl-8-ribityllumazine synthases of Brucella
JOURNAL OF BACTERIOLOGY; Año: 2006 vol. 188 p. 6135 - 6142
CRAIG, PO; BERGUER, PM; AINCIART, N; ZYLBERMAN, V; THOMAS, MG; MARTINEZ TOSAR, LJ; BULLOJ, A; BOCCACCIO, G; GOLDBAUM, FA
Multiple display of a protein domain on a bacterial polymeric scaffold
PROTEINS: STRUCTURE, FUNCTION AND GENETICS; Año: 2005 vol. 61 p. 1089 - 1100
SCIUTTO, E; TOLEDO, A; CRUZ, C; ROSAS, G; MENESES, G; LAPLAGNE, DA; AINCIART, N; CERVANTES, J; FRAGOSO, G; GOLDBAUM, FA
Brucella spp. lumazine synthase: a novel antigen delivery system
VACCINE; Año: 2005 vol. 23 p. 2784 - 2790
ZAREBSKI, L; URRUTIA, M; GOLDBAUM, FA
Llama single domain antibodies as a tool for molecular mimicry
JOURNAL OF MOLECULAR BIOLOGY; Año: 2005 vol. 349 p. 814 - 824
KLINKE, S; ZYLBERMAN, V; VEGA, DR; GUIMARAES, BG; BRADEN, BC; GOLDBAUM, FA
Crystallographic studies on decameric Brucella spp. Lumazine synthase: a novel quaternary arrangement evolved for a new function?
JOURNAL OF MOLECULAR BIOLOGY; Año: 2005 vol. 353 p. 124 - 137
CERUTTI, ML; ZAREBSKI, L; PRAT GAY, G; GOLDBAUM, FA
A viral DNA-binding domain elicits anti-DNA antibodies of different specificities
MOLECULAR IMMUNOLOGY; Año: 2005 vol. 42 p. 327 - 333
ZYLBERMAN, V; CRAIG, PO; KLINKE, S; BRADEN, BC; CAUERHFF, A; GOLDBAUM, FA
High order quaternary arrangement confers increased structural stability to Brucella sp. lumazine synthase
JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2004 vol. 279 p. 8093 - 8101
FORNASARI, MS; LAPLAGNE, DA; FRANKEL, N; CAUERHFF, A; GOLDBAUM, FA; ECHAVE, J
Sequence determinants of quaternary structure in lumazine synthase
MOLECULAR BIOLOGY AND EVOLUTION; Año: 2004 vol. 21 p. 97 - 107
LAPLAGNE, DA; ZYLBERMAN, V; AINCIART, N; STEWARD, MW; SCIUTTO, E; FOSSATI, CA; GOLDBAUM, FA
Engineering of a polymeric bacterial protein as a scaffold for the multiple display of peptides
PROTEINS: STRUCTURE, FUNCTION AND GENETICS; Año: 2004 vol. 57 p. 820 - 828
CAUERHFF, A; GOLDBAUM, FA; BRADEN, BC
Structural mechanism for affinity maturation of an anti-lysozyme antibody
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2004 vol. 101 p. 3539 - 3544