Data set on effect of amaranth proteins on the RAS system. In vitro, in vivo and ex vivo assays

SUÁREZ, SANTIAGO; APHALO, PAULA; RINALDI, GUSTAVO; QUIROGA, ALEJANDRA; AÑÓN, MARÍA CRISTINA

Data in Brief

Elsevier Sci Ltd

Año: 2020 vol. 29

2352-3409

Data set presented in this article is related to the research paperentitled ?Effect of amaranth proteins on the RAS system. In vitro,in vivo and ex vivo assays?, available in Food Chemistry [1]. In thisarticle, we evaluated the effect on systolic blood pressure ofspontaneously hypertensive rats (SHR) of different samples withamaranth proteins/peptides. The effect of these samples on RASsystem was evaluated using in vitro and ex vivo assays. The concentration of renin and angiotensin converting enzyme (ACE) was evaluated using two commercial ELISA kits. Renin concentration was estimated through a direct immunoassay and ACE concentration with an immunoassay based on a competitive inhibition. Inaddition, the ACE inhibitory activity in plasma was evaluated using a spectrophotometric assay according to [2]. Ex vivo experimentswere done with thoracic aorta extracted during the surgical procedure employed to obtain blood samples according to [3]. Data presented in this article recollect a very extensive work on how can be affect the RAS system in SHR model using amaranth protein/peptides as potential antihypertensive samples. These data could be useful to design novel functional foods for hypertensiveindividuals