SARA E. GIRALDO, ; MAURICIO BEDOYA,; CARLOS PEÑA-VARAS, ; PAULA A. SANTANA,; ISABEL L. BAZZOCCHI,; IGNACIO A. JIMÉNEZ,; MARIEL MARDER, ; NADEZDHA E. VERGEL,; MARIO F. GUERRERO,; DAVID RAMÍREZ

Iridoid esters from Valeriana pavonii Poepp. & Endl. as GABAA modulators: Structural insights in their binding mode and structure-activity relationship

Journal of Pharmacy & Pharmacognosy Research; Año: 2023 vol. 11 p. 367 - 380

MARCUCCI, CAROLINA; RADEMACHER, MARINA; KAMECKI, FABIOLA; PASTORE, VALENTINA; BACH, HERNÁN GERÓNIMO; RICCO, RAFAEL ALEJANDRO; WAGNER, MARCELO LUIS; KNEZ, DAMIJAN; GOBEC, STANISLAV; COLETTIS, NATALIA; MARDER, MARIEL

Biological Evaluation of Valeriana Extracts from Argentina with Potent Cholinesterase Inhibition for the Treatment of Neurodegenerative Disorders and Their Comorbidities—The Case of Valeriana carnosa Sm. (Caprifoliaceae) Studied in Mice

Pharmaceuticals; Año: 2023 vol. 16

WIES MANCINI, VICTORIA S. B.; DI PIETRO, ANABELLA A.; OLMOS, SOLEDAD; SILVA PINTO, PABLO; VENCE, MARIANELA; MARDER, MARIEL; IGAZ, LIONEL M.; MARCORA, MARÍA S.; PASQUINI, JUANA M.; CORREALE, JORGE D.; PASQUINI, LAURA A.

Colony‐stimulating factor‐1 receptor inhibition attenuates microgliosis and myelin loss but exacerbates neurodegeneration in the chronic cuprizone model

JOURNAL OF NEUROCHEMISTRY; Año: 2022

VACHETTA, VANINA S.; MARDER, MARIEL; TRONCOSO, MARÍA F.; ELOLA, MARÍA T.

Opportunities, obstacles and current challenges of flavonoids for luminal and triple-negative breast cancer therapy

European Journal of Medicinal Chemistry Reports; Año: 2022 vol. 6

KAMECKI, FABIOLA; KNEZ, DAMIJAN; CARVALHO, DIEGO; MARCUCCI, CAROLINA; RADEMACHER, MARINA; HIGGS, JOSEFINA; ZAKELJ, SIMON; MARCOS, ALEJANDRA; DE TEZANOS PINTO, FELICITAS; ABIN-CARRIQUIRY, JUAN ANDRÉS; GOBEC, STANISLAV; COLETTIS, NATALIA; MARDER, MARIEL

Multitarget 2′-hydroxychalcones as potential drugs for the treatment of neurodegenerative disorders and their comorbidities

NEUROPHARMACOLOGY; Año: 2021 vol. 201

LUKA REJC ; VANESSA GÓMEZ-VALLEJO; ANA JOYA; OSCAR MORENO; ANDER EGIMENDIA; PILAR CASTELLNOU; XABIER RÍOS-ANGLADA; UNAI COSSÍO; ZURIÑE BAZ; ROSSANA PASSANNANTE; IGNACIO TOBALINA-LARREA; PEDRO RAMOS-CABRER; ALBERT GIRALT; MAGDALENA SASTRE; ESTIBALIZ CAPETILLO-ZARATE; URBAN KOAK; DAMIJAN KNEZ; STANISLAV GOBEC; MARIEL MARDER.; ABRAHAM MARTIN; JORDI LLOP

Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease

Theranostics; Lugar: Sydney; Año: 2021 vol. 11 p. 6542 - 6559

KAMECKI, FABIOLA; MARCUCCI, CAROLINA; FERREIRA-GOMES, MARIELA; SABATIER, LAUREANO; KNEZ, DAMIJAN; GOBEC, STANISLAV; MONTI, JOSÉ LUIS EUGENIO; RADEMACHER, MARINA; MARCOS, ALEJANDRA; DE TEZANOS PINTO, FELICITAS; GAVERNET, LUCIANA; COLETTIS, NATALIA; MARDER, MARIEL

2’-Hydroxy-4’,5’-dimethyl-4-dimethylaminochalcone, a novel fluorescent flavonoid with capacity to detect aluminium in cells and modulate Alzheimer's disease targets

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY; Año: 2021 vol. 409

CAROLINA MARCUCCI ; JUAN MANUEL ANSELMI RELATS ; HERNÁN GERÓNIMO BACH ; FABIOLA KAMECKI; BEATRIZ VARELA ; MARCELO WAGNER; VALENTINA PASTORE; NATALIA COLETTIS ; RAFAEL RICCO ; MARIEL MARDER

Neurobehavioral evaluation and phytochemical characterization of a series of argentine valerian species

Heliyon; Año: 2020

KNEZ, DAMIJAN; COLETTIS, NATALIA; IACOVINO, LUCA G.; SOVA, MATEJ; PISLAR, ANJA; KONC, JANEZ; LESNIK, SAMO; HIGGS, JOSEFINA; KAMECKI, FABIOLA; MANGIALAVORI, IRENE; DOLSAK, ANA; ZAKELJ, SIMON; TRONTELJ, JURIJ; KOS, JANKO; BINDA, CLAUDIA; GOBEC, STANISLAV; MARDER, MARIEL

Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B

JOURNAL OF MEDICINAL CHEMISTRY; Lugar: Washington; Año: 2020 vol. 63 p. 1361 - 1387

JOSEFINA HIGGS ; CRISTINA WASOWSKI; ALEJANDRA MARCOS; MARKO JUKIC ; CARLOS HUMBERTO PAVÁN; STANISLAV GOBEC ; FELICITAS DE TEZANOS PINTO; NATALIA COLETTIS; MARIEL MARDER

Chalcone derivatives: Synthesis, in vitro and in vivo evaluation of their anti-anxiety, anti-depression and analgesic effects

HELIYON; Año: 2019

M.ONTIVEROS ; D.RINALDI; M.MARDER ; M.V.ESPELT; I.MANGIALAVORI; M.VIGIL; J.P.ROSSI; M.FERREIRA-GOMES

Natural flavonoids inhibit the plasma membrane Ca2+-ATPase

BIOCHEMICAL PHARMACOLOGY; Lugar: Amsterdam; Año: 2019

PASTORE, VALENTINA; WASOWSKI, CRISTINA; MARTIN, PEDRO; ENRIQUE, ANDREA; HIGGS, JOSEFINA; BRUNO-BLANCH, LUIS E.; MILESI, VERONICA; MARDER, MARIEL

N-propyl-2,2-diphenyl-2-hydroxyacetamide, a novel α-hydroxyamide with anticonvulsant, anxiolytic and antidepressant-like effects that inhibits voltage-gated sodium channels

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2018 vol. 819 p. 270 - 280

MARIA L VILLALBA ; ANDREA V ENRIQUE; JOSEFINA HIGGS; ROCIO A CASTAÑO; SOFIA GOICOECHEA; FACUNDO D TABORDA; LUCIANA GAVERNET; DANIELA I LICK; MARIEL MARDER; LUIS E BRUNO BLANCH

Novel sulfamides and sulfamates derived from amino esters: Synthetic studies and anticonvulsant activity

EUROPEAN JOURNAL OF PHARMACOLOGY; Lugar: Amsterdam; Año: 2016 vol. 774 p. 55 - 63

H.C. HOYOS; M. MARDER; R. ULRICH, ; V. GUDI; M. STANGEL; G.A. RABINOVICH; L.A. PASQUINI; J.M. PASQUINI

The role of galectin-3: from oligodendroglial differentiation and myelination to demyelination and remyelination processes in a cuprizone-induced demyelination model.

ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY.; Año: 2016 vol. 949 p. 331 - 332

H.C. HOYOS; M. RINALDI; S.P. MENDEZ-HUERGO; M. MARDER; G.A RABINOVICH; J.M. PASQUINI; L.A PASQUINI

Galectin-3 controls the response of microglial cells to limit cuprizone-induced demyelination

NEUROBIOLOGY OF DISEASE; Lugar: Amsterdam; Año: 2014 vol. 62 p. 441 - 455

V. PASTORE; C. WASOWSKI; J. HIGGS; I. C. MANGIALAVORI; L. E. BRUNO-BLANCH; M. MARDER

A synthetic bioisoster of trimethadione and phenytoin elicits anticonvulsant effect, protects the brain oxidative damage produced by seizures and exerts antidepressant action in mice

EUROPEAN NEUROPSYCHOFARMACOLOGY; Lugar: Amsterdam; Año: 2014 vol. 24 p. 1405 - 1414

M. H. ESTRADA; H. INSUASTY; L. E. CUCA; M. MARDER; A. FIERRO; M. F. GUERRERO

Anticonvulsant profile of 2-ethylthio-7-methyl-4-(4-methylphenyl) pyrazolo[1,5-a][1,3,5]triazine

BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES; Lugar: Ribeirao Preto; Año: 2014 vol. 50 p. 73 - 80

V. PASTORE; L. SABATIER; A. ENRIQUE; M. MARDER; L. E. BRUNO-BLANCH

Synthesis and anticonvulsant activity of biosisoters of trimethadione, N-derivative-1,2,3-oxathiazolidin-4-one-2,2-dioxides from α-hydroxyamides.

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2013 vol. 21 p. 841 - 846

S. E. GIRALDO; J. RINCÓN; M. F. GUERRERO; I. LÓPEZ; I. A. JIMÉNEZ; M. MARDER; C. WASOWSKI; N. E. VERGEL

Valepotriate Hydrines Isolated from an Anticonvulsant Fraction of Valeriana pavonii Poepp. & Endl.

ACTA FARM. BONAERENSE; Lugar: Buenos Aires; Año: 2013 vol. 32 p. 1224 - 1230

J. HIGGS; C. WASOWSKI; L. M. LOSCALZO; M. MARDER

In vitro binding affinities of a series of flavonoids for mu-opioid receptors. Antinociceptive effect of the synthetic flavonoid 3,3-dibromoflavanone in mice.

NEUROPHARMACOLOGY; Lugar: Amsterdam; Año: 2013 vol. 72 p. 9 - 19

MILLET, V.; MARDER, M.; PASQUINI, L.A.

Adult CNP::EGFP transgenic mice: a suitable model of chronic demyelination

EXPERIMENTAL NEUROLOGY; Año: 2012 vol. 233 p. 490 - 504

C. WASOWSKI; L. GAVERNET; I. A. BARRIOS; M. L. VILLALBA; V. PASTORE; G. SAMAJA; A. ENRIQUE; L. E. BRUNO-BLANCH; M. MARDER

N,N'-dicyclohexylsulfamide and N,N'-diphenethylsulfamide, anticonvulsant sulfamides with affinity for the benzodiazepine binding site of the GABAA receptor and anxiolytic activity in mice

BIOCHEMICAL PHARMACOLOGY; Año: 2012 vol. 83 p. 253 - 259

WASOWSKI, CRISTINA; LOSCALZO, LEONARDO M.; HIGGS, JOSEFINA; MARDER MARIEL

Chronic intraperitoneal and oral treatments with hesperidin induce central nervous system effects in mice

PHYTOTHERAPY RESEARCH; Año: 2012 vol. 26 p. 308 - 312

MARIANO G. CARDENAS; VIVIANA C. BLANK,; MARIEL N. MARDER ; LEONOR P. ROGUIN

2'-Nitroflavone induces apoptosis and modulates mitogen-activated protein kinase pathways in human leukaemia cells

ANTICANCER DRUGS; Lugar: Philadelphia; Año: 2012 vol. 23 p. 815 - 826

WASOWSKI, CRISTINA; MARDER MARIEL

Flavonoids as GABAA receptor ligands: the whole story?

Journal of Experimental Pharmacology; Año: 2012 vol. 4 p. 9 - 24

C. WASOWSKI; M. MARDER

Central nervous system activities of two diterpenes isolated from Aloysia virgata.

PHYTOMEDICINE; Año: 2011 vol. 18 p. 393 - 401

L. A. PASQUINI; V. MILLET; H. C. HOYOS; J. P.GIANNONI; D. O.CROCI; M. MARDER; F. T. LIU; G. A. RABINOVICH; J . M. PASQUINI

Galectin-3-glycan lattices drive oligodendrocyte differentiation to control myelin integrity and function

CELL DEATH AND DIFFERENTIATION; Año: 2011 vol. 18 p. 1746 - 1756

L. M. LOSCALZO; C. WASOWSKI; M. MARDER

Anxiolytic-like effects of Tilia petiolaris DC. inflorescences infusion.

ACTA FARM. BONAERENSE; Año: 2011 vol. 30 p. 354 - 358

LEONARDO M LOSCALZO; TIN T YOW; CRISTINA WASOWSKI; MARY CHEBIB; MARIEL MARDER

Hesperidin induces antinociceptive effect in mice and its aglicone, hesperetin, binds to mu-opioid

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Año: 2011 vol. 99 p. 333 - 341

SARA EMILIA GIRALDO; JAVIER RINCÓN; PILAR PUEBLA; MARIEL MARDER; CRISTINA WASOWSKI; NADEZDHA VERGEL; MARIO FRANCISCO GUERRERO

Isovaleramide, anticonvulsant molecule isolated from Valeriana pavonii

BIOMéDICA; Año: 2010 vol. 30 p. 245 - 250

M.G.CARDENAS; E. ZOTTA; M. MARDER; LEONOR P. ROGUIN

In vitro induction of apoptosis and in vivo effects of a flavone nitroderivative in murine mammary adenocarcinoma cells

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Año: 2009 vol. 125 p. 222 - 228

C. MARTINEZ; S. P. FERNANDEZ; L. M. LOSCALZO; C. WASOWSKI; A. C. PALADINI; M. MARDER; J. H MEDINA; H. VIOLA

Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1/2 levels in mice.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Año: 2009 vol. 92 p. 291 - 296

L. M. LOSCALZO; C. WASOWSKI; M. MARDER

Neuroactive flavonoid glycosides from Tilia petiolaris DC. extracts

PHYTOTHERAPY RESEARCH; Año: 2009 vol. 23 p. 1453 - 1459

VIVIAN OVIEDO; MILDRED GARCÍA; CECILIA DÍAZ; MARIEL MARDER; MIRTES COSTA; JAVIER RINCÓN; CEFERINO SÁNCHEZ; MARIO GUERRERO

Extracto y fracción alcaloidal de Annona muricata con actividad de tipo ansiolítica en ratones

Revista colombiana de ciencias químico farmacéuticas; Año: 2009 vol. 38 p. 105 - 120

FILIPE SILVEIRA DUARTE; MARIEL MARDER; ALEXANDRE ADEMAR HOELLER; MARCELO DUZZIONI; BEATRIZ GARCIA MENDES; MOACIR GERALDO PIZZOLATTI; THEREZA CHRISTINA MONTEIRO DE LIMA

Anticonvulsant and anxiolytic-like effects of compounds isolated from Polygala sabulosa (Polygalaceae) in rodents: in vitro and in vivo interactions with benzodiazepine binding sites

PSYCHOPHARMACOLOGY; Año: 2008 vol. 193 p. 351 - 360

R. FURTMUELLER; B. FURTMUELLER; A. C. PALADINI; C. WASOWSKI; M. MARDER; S. HUCK; W. SIEGHART

6,3'-Dinitroflavone is a low efficacy modulator of GABAA receptors

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2008 vol. 591 p. 142 - 146

LEONARDO M. LOSCALZO; CRISTINA WASOWSKI; ALEJANDRO C. PALADINI; MARIEL MARDER

Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2008 vol. 580 p. 306 - 313

M. G. CÁRDENAS; V. C. BLANK; M. MARDER; L. P. ROGUIN

2´-nitroflavone induces cell cycle arrest and apoptosis in HeLa human cervical carcinoma cells

CANCER LETTERS; Año: 2008 vol. 268 p. 146 - 157

M.C. HELLIÓN-IBARROLA; D.A. IBARROLA; Y. MONTALBETTI; M.L. KENNEDY; O. HEINICHEN; M. CAMPUZANO; J. TORTORIELLO; S. FERNÁNDEZ; C. WASOWSKI; M. MARDER; T.C.M DE LIMA; S. MORA

The anxiolytic-like effects of Aloysia polystachya (Verbenaceae) in mice.

JOURNAL OF ETHNOPHARMACOLOGY; Año: 2006 vol. 105 p. 400 - 408

S. P. FERNÁNDEZ; C. WASOWSKI; L. M. LOSCALZO; R. E. GRANGER; G. A. R. JOHNSTON; A. C. PALADINI; M. MARDER

Central nervous system depressant action of flavonoid glycosides.

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2006 vol. 539 p. 168 - 176

M. CÁRDENAS; M. MARDER; V. C. BLANK; L. P. ROGUIN

Antitumor activity of some natural flavonoids and synthetic derivatives on various human and murine cancer cell lines

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2006 vol. 14 p. 2966 - 2971

SEBASTIÁN P. FERNÁNDEZ; CRISTINA WASOWSKI; ALEJANDRO C. PALADINI; MARIEL MARDER

Synergistic interaction between hesperidin, a natural flavonoid,and diazepam

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2005 vol. 512 p. 189 - 198

VIVIANA C. BLANK; CECILIA POLI; MARIEL MARDER; LEONOR P. ROGUIN

Antiproliferative activity of vatious natural flavonoids and synthetic derivatives. Additive effect of interferon-alfa2b.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 2004 vol. 14 p. 133 - 136

SEBASTIÁN FERNÁNDEZ; CRISTINA WASOWSKI; ALEJANDRO C. PALADINI; MARIEL MARDER

Sedative and sleep enhancing properties of linarin, a flavonoid isolated from Valeriana officinalis.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Año: 2004 vol. 77 p. 399 - 404

M. MARDER; H. VIOLA; C. WASOWSKI; S. FERNÁNDEZ; J. H. MEDINA; A. C. PALADINI

6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Año: 2003 vol. 75 p. 537 - 545

M. MARDER; A. C. PALADINI

GABAA-Receptor ligands of flavonoid structure

Current Topics in Medicinal Chemistry; Año: 2002 vol. 2 p. 853 - 867

C. WASOWSKI; M. MARDER; H. VIOLA,; J. H. MEDINA; A. C. PALADINI

. Isolation and Identification of 6-Methylapigenin, a Competitive Ligand for the Brain GABAA Receptors, from Valeriana wallichii D.C.

PLANTA MEDICA; Año: 2002 vol. 68 p. 934 - 936

MARDER, MARIEL; ESTIU, G.; BRUNO BLANCH, L.; VIOLA, HAYDEE; WASOWSKI, CRISTINA; MEDINA, JORGE H.; PALADINI, ALEJANDRO C; NORA MARIEL MARDER

Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABAA receptor complex

Bioorg. Med. Chem; Año: 2001 vol. 9 p. 323 - 335

M. MARDER; C. WASOWSKI; A. C. PALADINI

Las plantas productoras de drogas farmacéuticas

Ciencia Hoy; Lugar: 65, pag: 12-19; Año: 2001 vol. 65 p. 12 - 19

M. MARDER; H. VIOLA; C. WASOWSKI; O. GIORGI; A. C. PALADINI; J. H. MEDINA

6,3'-dibromoflavone and 6-nitro-3'-bromoflavone: new additions to the 6,3'-disubstituted flavone family of high affinity ligands of the brain benzodiazepine binding site with agonistic properties

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2000 vol. 273 p. 694 - 698

VIOLA, H; WOLFMAN, C; MARDER, NORA M; GOUTMAN, JD; BIANCHIN, M; WASOWSKI, C; CALVO, DJ; IZQUIERDO, I; PALADINI, ALEJANDRO C; MEDINA, JH; NORA MARIEL MARDER

6-Chloro-3'-nitroflavone is a potent ligand for the benzodiazepine binding site of the GABAa receptor devoid of intrinsic activity

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Año: 2000 vol. 65 p. 313 - 320

A. C. PALADINI; M. MARDER; H. VIOLA; C. WOLFMAN; C. WASOWSKI; J. H. MEDINA

Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds.

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 1999 vol. 51 p. 519 - 526

H. VIOLA; M. MARDER; J. NUÑEZ; L. IZQUIERDO; C. WASOWSKI; C. WOLFMAN; P. ARDENGHI; D. BARROS; J. H. MEDINA; A. C. PALADINI

6-Methyl-3'-bromoflavone, a high affinity ligand for the benzodiazepine binding site of the GABAA receptor with some agonistic properties.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 1999 vol. 262 p. 643 - 646

M. MARDER; H. VIOLA; J. A. BACIGALUPPO; M. I. COLOMBO; C. WASOWSKI; C. WOLFMAN; J. H. MEDINA; E. A. RUVEDA; A. C. PALADINI

Detection of benzodiazepine receptors ligands in small libraries of flavone derivatives synthesized by solution phase combinatorial chemistry.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 1998 vol. 249 p. 481 - 485

C. WOLFMAN; H. VIOLA; M. MARDER; P. ARDENGHI; C. WASOWSKI; N. SCHRODER; I. IZQUIERDO; E. A. RÚVEDA; A. C. PALADINI; J. H. MEDINA

Pharmacological characterization of 6-bromo-3'-nitroflavone, a synthethic flavonoid with high affinity for the benzodiazepine receptors.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Año: 1998 vol. 61 p. 239 - 246

H. VIOLA; M. MARDER,; C. WOLFMAN; C. WASOWSKI; J. H. MEDINA; A. C. PALADINI

Central Nervous System effects of natural and synthetic flavonoids.

Journal of the Argentine Chemical Society; Año: 1998 vol. 86 p. 229 - 236

J. H. MEDINA; H. VIOLA; C. WOLFMAN; M. MARDER; C. WASOWSKI; D. CALVO; A. C. PALADINI

Neuroactive flavonoids: new ligands for the Benzodiazepine receptors.

PHYTOMEDICINE; Año: 1998 vol. 5 p. 235 - 243

J. H. MEDINA; H. VIOLA; C. WOLFMAN; M. MARDER; C. WASOWSKI; D. CALVO; A. C. PALADINI

Overview: Flavonoids: A new family of benzodiazepine receptor ligands.

NEUROCHEMICAL RESEARCH; Año: 1997 vol. 22 p. 419 - 425

H. VIOLA; C. WASOWSKI; M. MARDER; C. WOLFMAN; A. C. PALADINI; J. H. MEDINA

Sedative and hypnotic properties of Salvia guaranítica St. Hill. and of its active principle, Cirsiliol.

PHYTOMEDICINE; Año: 1997 vol. 4 p. 45 - 50

H. VIOLA; M. MARDER; C. WOLFMAN; C. WASOWSKI; J. H. MEDINA; A. C. PALADINI

6-Bromo-3'-nitroflavone, a new high affinity benzodiazepine receptor agonist, recognizes two populations of cerebral cortical binding sites.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 1997 vol. 7 p. 373 - 378

M. MARDER; J. ZINCZUK; M. I. COLOMBO; C. WASOWSKI; H. VIOLA; C. WOLFMAN; J. H. MEDINA; E. A. RÚVEDA; A. C. PALADINI

Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 1997 vol. 7 p. 2003 - 2008

C. WOLFMAN; H. VIOLA; M. MARDER; C. WASOWSKI; P. ARDENGHI; I. IZQUIERDO; A. C. PALADINI; J. H. MEDINA

Anxioselective properties of 6,3'-dinitroflavone, a high affinity benzodiazepine receptor ligand.

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 1996 vol. 318 p. 23 - 30

M. MARDER; H. VIOLA; C. WASOWSKI; C. WOLFMAN; P. G. WATERMAN; B. K. CASSELS; J. H. MEDINA; A. C. PALADINI

6-Bromoflavone, a high affinity ligand for the central benzodiazepine receptors is a member of a family of active flavonoids.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 1996 vol. 223 p. 284 - 389

M. MARDER; C. WASOWSKI; H. VIOLA; C. WOLFMAN; P. WATERMAN; J. H. MEDINA; A. C. PALADINI

Cirsiliol and Caffeic Acid Ethyl Ester, Isolated from Salvia guaranitica, are Competitive Ligand for the Central Benzodiazepine Receptor.

PHYTOMEDICINE; Año: 1996 vol. 3 p. 29 - 31

M. MARDER; H. VIOLA; C. WASOWSKI; C. WOLFMAN; P. WATERMAN; J. H. MEDINA; A. C. PALADINI

6,3'-Dinitroflavone: a high affinity ligand for the BZD-R with potent anxiolytic properties.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Año: 1995 vol. 5 p. 2717 - 2720

N. SBARBATI NUDELMAN; MARIEL MARDER; ALEJANDRA GUREVICH

Reaction of 2,6-dinitroanisol with cyclohexylamine in toluene-octanol binary solvents. A further support for the "dimer nucleophile mechanism" in ANS

JOURNAL OF THE CHEMICAL SOCIETY. PERKIN TRANSACTIONS 2 (2001); Año: 1993 vol. 2 p. 229 - 234