PERSONAL DE APOYO
MOLINA Veronica Carolina
artículos
Título:
Dietary supplementation with probiotic strain improves immune-health in aged mice
Autor/es:
VERÓNICA CAROLINA MOLINA; MARTA MEDICI; VILLENA JULIO; GRACIELA FONT DE VALDEZ; MARIA PIA TARANTO
Revista:
Open Journal of Immunology
Editorial:
x
Referencias:
Año: 2016 vol. 6 p. 73 - 78
ISSN:
2162-450X
Resumen:
AbstractAgeing is associated with several anatomical and physiological changes of the organism, and theincrease in global elderly population promotes the research to develop strategies to improve theirquality of life. In this work, we characterized the immunological alterations naturally producedduring aging in a mice model, and evaluated the effect of probiotic Lactobacillus (L.) rhamnosusCRL1505 administration on those immunological parameters. We demonstrated that L. rhamosusCRL1505 was able to improve peritoneal macrophages phagocytic activity, and the number of intestinalIgA+ cells in aged mice, reaching values of those parameters similar to young adult mice.The results of this work indicate that is plausible that the immunobiotic CRL1505 strain may findapplications as a beneficial immunomodulator in aging to reinforce the intestinal and systemicimmunity. The immune modulation in aging induced by L. rhamnosus CRL1505 could lead to thedevelopment of new strategies for functional foods specifically tailored for the elderly.
