Probiotic cell cultivation

SANTOS M.; TYMCZYSZYN E,; GOLOWCZYC, M. A.,; MOBILI, P; GOMEZ ZAVAGLIA, A.

Advances in Probiotic Technology

CRC Press Taylor and Francis Group

Año: 2015; p. 45 - 75

Research on lactic acid bacteria (LAB) and probiotics is nowadays an interdisciplinary field going beyond the fundamental microbiology. The comercial importance of certain microbial metabolites (i.e., lactic acid) has led to the use of these microorganisms as biological factories of valuable products. On the other hand, the worldwide ecological conscience about the importance of reducing industrial contamination has stimulated the use of certain effluents as non-traditional culture meda for LAB and probiotics. This approach has two advantages: the decrease of industrial costs derived from decontamination of effluents and the lower cost of culture media.Monitoring bacterial growth is another example of the current interdisciplinarity in the research of LAB and probiotics. Fundamental field like physics, mathematics and statistics were determinant for the current development of enviromentally friendly analytical methods allowing in situ and in real time monitoring.In this chapter, an overview of probiotic cell cultivation and monitoring including the use of both traditional and non-traditional culture media., the production of commercially valuable products and biomass is reported. Special emphasis was put on the fundamentals and interpretation of the information provided by analytical methods used for monitoring