Prevalence of colistin-resistant Escherichia coli in foods and food-producing animals through the food chain: A worldwide systematic review and meta-analysis

LENCINA, FLORENCIA AYLEN; BERTONA, MATÍAS; STEGMAYER, MARÍA ANGELES; OLIVERO, CAROLINA RAQUEL; FRIZZO, LAUREANO SEBASTIÁN; ZIMMERMANN, J.A.; SIGNORINI, MARCELO LISANDRO; SOTO, LORENA P.; ZBRUN, MA VIRGINIA

Heliyon

Heliyon

Año: 2024

2405-8440

The purpose of this systematic review and meta-analysis was to summarize the available scientific evidence on the prevalence of colistin-resistant Escherichia coli strains isolated from foods and food-producing animals, the mobile colistin-resistant genes involved, and the impact of the associated variables. A systematic review was carried out in databases according to selection criteria and search strategies established a priori. Random‐effect meta‐analysis models were fitted to estimate the prevalence of colistin-resistant Escherichia coli and to identify the factors associated with the outcome. In general, 4.79% (95% CI: 3.98%–5.76%) of the food and food-producing animal samples harbored colistin-resistant Escherichia coli (total number of colistin-resistant Escherichia coli/total number of samples), while 5.70% (95% confidence interval: 4.97%–6.52%) of the E. coli strains isolated from food and food-producing animal samples harbored colistin resistance (total number of colistin-resistant Escherichia coli/total number of Escherichia coli isolated samples). The prevalence of colistin-resistant Escherichia coli increased over time (P