Formulation of Sustainable Biopolymer-Based Nanoparticles Obtained via Media Milling for Chia Oil Vehiculization in Pickering Emulsions

BORDÓN GABRIELA; LUCÍA LOPEZ VIDAL; NAHUEL CAMACHO; MARCELA L. MARTÍNEZ; MARÍA CECILIA PENCI; CECILIO CARRERA; VÍCTOR M. PIZONES RUIZ-HENESTROSA; SANTIAGO PALMA; PABLO RIBOTTA

Biology and Life Sciences Forum

MDPI

Lugar: Basel; Año: 2023 vol. 25

2673-9976

Sustainable corn starch nanoparticles were prepared using media milling to stabilizeomega-3-rich Pickering emulsions based on chia oil. The milling conditions were as follows: 24 h(milling time), 0.4–0.6 mm (bead diameter), 1600 rpm (impeller speed), 30% (volume occupied bythe grinding media), 7% w/v (starch concentration), and 0, 0.07 and 1% w/v of sodium dodecylsulfate (SDS). Nanosuspensions containing 7% w/v of starch and the three concentrations of SDSwere filtered, centrifuged, homogenized, and spray-dried to obtain redispersible powders. Theparticle size ranges were 2288 ± 211, 385 ± 21, and 278 ± 11 nm with 0, 0.07 and 1% w/v of SDS,respectively. The most stable backscattering profiles obtained during a period of one week wereobserved with 0.07 and 1% w/v of SDS. Therefore, the surface dilatational rheology of these particlesadsorbed at chia oil/water interfaces was studied. A rapid decrease in the interfacial tension within1 h was obtained with 1% w/v of SDS (down to 3 mN/m). Moreover, the most stable particle sizeafter redispersion was obtained with the highest concentration of SDS. Finally, Pickering emulsionswere prepared, and significant coalescence was observed with 0 and 0.07% w/v of SDS (within afew minutes). Nonetheless, in the presence of 1% w/v of SDS, oil droplets showed mean diametersand polydispersity indexes of 280.13 ± 4.60 nm and 0.35 ± 0.02, respectively, with no significantvariations during storage for around 1 month. The results show that wet-stirred media milling canbe applied to produce sustainable, new food-grade starch nanoparticles able to deliver bioactivecompounds from chia oil.