INVESTIGADORES
MAS Ignacio Agustin
congresos y reuniones científicas
Título:
PharmaSat: Drug Dose Dependence Results from an Autonomous Microsystem-Based Small Satellite in Low-Earth Orbit
Autor/es:
ANTHONY RICCO; MACARENA PARRA; MATTHEW PICCINI; DAVID NIESEL; MICHAEL MCGINNIS; CHRISTOPHER KITTS; IGNACIO MAS; MICHAEL RASAY; ELWOOD AGASID; ED LUZZI; KAROLYN RONZANO; DAVID SQUIRES; BRUCE YOST
Lugar:
Hilton Head, SC
Reunión:
Workshop; TRF Solid State Sensors, Actuators and Microsystems Workshop; 2010
Institución organizadora:
Transducer Research Foundation
Resumen:
We designed, built, tested, space-qualified, launched, anddownlinked bioanalytical data from PharmaSat, the first fullyautonomous outer-space pharmaceutical dose-response bioanalyticalsystem on a free-flying satellite. PharmaSat tracks microorganismculture population density and metabolic activity in 48 microwellsvia 3-color optical absorbance. Its 5.1-kg total mass includessolar cells, integrated spacecraft bus module (power/batteries/control/communications), and a sealed containment vessel housingthe biofluidic, optical, thermal, and sensor subsystems. Data wereobtained from all subsystems over several days following nutrientintroduction to initiate growth of Saccharomyces cerevisiae, followedby challenges with three dose levels of an antifungal agent.
