PHAM V; BRUEMMER, KEVIN J.; TOEL J; GE, EVA; TENNEY, L; WARD, C; DINGLER, FELIX A.; MILLINGTON, CHRISTOPHER L.; GARCIA-PRIETO, C; PULOS-HOLMES; INGOLIA, N; PONTEL, LUCAS B.; ESTELLER, M; PATEL, KETAN J.; NOMURA, D; CHANG, CHRISTOPHER J.

Formaldehyde regulates S-adenosylmethionine biosynthesis and one-carbon metabolism

Science; Año: 2023 vol. 382

MONGE, MARÍA EUGENIA; MARTINEFSKI, MANUELA R.; BOLLINI, MARIELA; PONTEL, LUCAS B.

UHPLC-HRMS-Based Analysis of S-Hydroxymethyl-Glutathione, GSH, and GSSG in Human Cells

Methods in molecular biology (Clifton, N.J.); Lugar: Londres; Año: 2023 vol. 2675 p. 117 - 132

PONTEL, LUCAS B.; BUENO-COSTA, ALBERTO; MORELLATO, AGUSTÍN E.; CARVALHO SANTOS, JULIANA; ROUÉ, GAËL; ESTELLER, MANEL

Acute lymphoblastic leukemia necessitates GSH-dependent ferroptosis defenses to overcome FSP1-epigenetic silencing

Redox Biology; Año: 2022 vol. 55

UMANSKY, CARLA; MORELLATO, AGUSTÍN E.; RIECKHER, MATTHIAS; SCHEIDEGGER, MARCO A.; MARTINEFSKI, MANUELA R.; FERNÁNDEZ, GABRIELA A.; PAK, OLEG; KOLESNIKOVA, KSENIA; REINGRUBER, HERNÁN; BOLLINI, MARIELA; CROSSAN, GERRY P.; SOMMER, NATASCHA; MONGE, MARÍA EUGENIA; SCHUMACHER, BJÖRN; PONTEL, LUCAS B.

Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity

NATURE COMMUNICATIONS; Año: 2022 vol. 13

LUCAS PONTEL

El origen del Cáncer, nuestra alimentación y los antioxidantes

Ciencia Hoy; Lugar: Buenos Aires; Año: 2022 vol. 30

AGUSTÍN MORELLATO; CARLA UMANSKY; LUCAS B. PONTEL

The Toxic side of one-carbon metabolism and epigenetics

Redox Biology; Año: 2021

CARLA UMANSKY; AGUSTÍN MORELLATO; LUCAS B. PONTEL

Illuminating Cellular Formaldehyde

NATURE COMMUNICATIONS; Año: 2021 vol. 25

DINGLER, FELIX A.; WANG, MENG; MU, ANFENG; MILLINGTON, CHRISTOPHER L.; OBERBECK, NINA; WATCHAM, SAM; PONTEL, LUCAS B.; KAMIMAE-LANNING, ASHLEY N.; LANGEVIN, FREDERIC; NADLER, CAMILLE; CORDELL, REBECCA L.; MONKS, PAUL S.; YU, RUI; WILSON, NICOLA K.; HIRA, ASUKA; YOSHIDA, KENICHI; MORI, MINAKO; OKAMOTO, YUSUKE; OKUNO, YUSUKE; MURAMATSU, HIDEKI; SHIRAISHI, YUICHI; KOBAYASHI, MASAYUKI; MORIGUCHI, TOSHINORI; OSUMI, TOMOO; KATO, MOTOHIRO; MIYANO, SATORU; ITO, ETSURO; KOJIMA, SEIJI; YABE, HIROMASA; YABE, MIHARU; MATSUO, KEITARO; OGAWA, SEISHI; GÖTTGENS, BERTHOLD; HODSKINSON, MICHAEL R.G.; TAKATA, MINORU; PATEL, KETAN J.

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans

MOLECULAR CELL; Año: 2020

REINGRUBER, HERNÁN; PONTEL, LUCAS BLAS

Formaldehyde metabolism and its impact on human health

Current Opinion in Toxicology; Año: 2018 vol. 9 p. 28 - 34

BURGOS-BARRAGAN, GUILLERMO; WIT, NIEK; MEISER, JOHANNES; DINGLER, FELIX A.; PIETZKE, MATTHIAS; MULDERRIG, LEE; PONTEL, LUCAS B.; ROSADO, IVAN V.; BREWER, THOMAS F.; CORDELL, REBECCA L.; MONKS, PAUL S.; CHANG, CHRISTOPHER J.; VAZQUEZ, ALEXEI; PATEL, KETAN J.

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

NATURE; Año: 2017 vol. 548 p. 549 - 554

BRUEMMER, KEVIN J.; WALVOORD, RYAN R.; BREWER, THOMAS F.; BURGOS-BARRAGAN, GUILLERMO; WIT, NIEK; PONTEL, LUCAS B.; PATEL, KETAN J.; CHANG, CHRISTOPHER J.

Development of a General Aza-Cope Reaction Trigger Applied to Fluorescence Imaging of Formaldehyde in Living Cells

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Año: 2017 vol. 139 p. 5338 - 5350

ALEJANDRO PEZZA; LUCAS B. PONTEL; CAROLINA LOPÉZ; FERNANDO C. SONCINI

Compartment and signal-specific codependence in the transcriptional control of Salmonella periplasmic copper homeostasis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2016 vol. 113 p. 11573 - 11578

LUCAS B. PONTEL; JUDITH LANGENICK; IVAN ROSADO; XIAO-YIN ZHANG; DAVID TRAYNOR; ROB KAY; KJ PATEL

Xpf suppresses the mutagenic consequences of phagocytosis in Dictyostelium

JOURNAL OF CELL SCIENCE; Lugar: Cambridge; Año: 2016 vol. 129 p. 4449 - 4454

LUCAS BLAS PONTEL *; IVAN ROSADO *; BURGOS-BARRAGAN G; GARAYCOECHEA JI; YU R; ARENDS MJ; CHANDRASEKARAN G; BROECKER V; WEI W; LIU L; SWENBERG JA; CROSSAN GP; PATEL KJ

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.

MOLECULAR CELL; Lugar: United States; Año: 2015 vol. 60 p. 177 - 188

LUCAS B. PONTEL *; NADIA SCAMPOLI *; PORWOLLIK S.; CHECA S.K; MCCLELLAND M. ; FERNANDO SONCINI

Identification of a Salmonella ancillary copper detoxification mechanism by a comparative analysis of the genome-wide transcriptional response to copper and zinc excess

MICROBIOLOGY-UK; Lugar: London; Año: 2014 vol. 160 p. 1659 - 1669

LUCIANO ABRIATA *; LUCAS BLAS PONTEL *; ALEJANDRO J. VILA; DAL PERARO M. ; FERNANDO SONCINI

A dimerization interface mediated by functionally critical residues creates interfacial disulfide bonds and copper sites in CueP

JOURNAL OF INORGANIC BIOCHEMISTRY; Lugar: Amsterdam; Año: 2014 vol. 140 p. 199 - 201

LUCAS B. PONTEL; ALEJANDRO PEZZA; FERNANDO C. SONCINI

Copper Stress Targets the Rcs System To Induce Multiaggregative Behavior in a Copper-Sensitive Salmonella Strain

JOURNAL OF BACTERIOLOGY; Año: 2010 vol. 1292 p. 6287 - 6290

LUCAS B. PONTEL; FERNANDO C. SONCINI

Alternative periplasmic copper-resistance mechanisms in Gram negative bacteria.

MOLECULAR MICROBIOLOGY; Año: 2009 vol. 73 p. 215 - 225

SPINELLI, SILVANA V.; PONTEL, LUCAS B.; GARCíA VéSCOVI, ELEONORA; SONCINI, FERNANDO C.

Regulation of magnesium homeostasis in Salmonella: Mg2+ targets the mgtA transcript for degradation by RNase E

FEMS MICROBIOLOGY LETTERS; Año: 2008 vol. 280 p. 226 - 234

PONTEL, LUCAS B.; AUDERO, MARÍA E. PÉREZ; ESPARIZ, MARTÍN; CHECA, SUSANA K.; SONCINI, FERNANDO C.

GolS controls the response to gold by the hierarchical induction of Salmonella-specific genes that include a CBA efflux-coding operon

MOLECULAR MICROBIOLOGY; Año: 2007 vol. 66 p. 814 - 825

MARTÍN ESPARIZ *; SUSANA K. CHECA *; MARÍA E. PÉREZ AUDERO; LUCAS B. PONTEL; FERNANDO C. SONCINI

Dissecting the Salmonella response to copper

MICROBIOLOGY-UK; Año: 2007 vol. 159 p. 2990 - 2998