SINGHAL, SANDEEP K.; BYUN, JUNG S.; YAN, TINGFEN; YANCEY, RYAN; CABAN, AMBAR; HERNANDEZ, SARA GIL; BUFFORD, SEDIQUA; HEWITT, STEPHEN M.; WINFIELD, JOY; PRADHAN, JAYA; MUSTKOV, VESCO; MCDONALD, JASMINE A.; PÉREZ-STABLE, ELISEO J.; NÁPOLES, ANNA MARÍA; VOHRA, NASREEN; DE SIERVI, ADRIANA; YATES, CLAYTON; DAVIS, MELISSA B.; YANG, MEI; TSAI, YIEN CHE; WEISSMAN, ALLAN M.; GARDNER, KEVIN

Protein expression of the gp78 E3 ligase predicts poor breast cancer outcome based on race

JCI Insight; Año: 2022 vol. 7

DUCA, ROCÍO BELÉN; MASSILLO, CINTIA; FARRÉ, PAULA LUCÍA; GRAÑA, KAREN DANIELA; MORO, JUANA; GARDNER, KEVIN; LACUNZA, EZEQUIEL; DE SIERVI, ADRIANA

Hsa-miR-133a-3p, miR-1-3p, GOLPH3 and JUP combination results in a good biomarker to distinguish between prostate cancer and non-prostate cancer patients

Frontiers in Oncology; Año: 2022 vol. 12

SINGHAL, SANDEEP K.; BYUN, JUNG S.; PARK, SAMSON; YAN, TINGFEN; YANCEY, RYAN; CABAN, AMBAR; HERNANDEZ, SARA GIL; HEWITT, STEPHEN M.; BOISVERT, HEIKE; HENNEK, STEPHANIE; BOBROW, MARK; AHMED, MD SHAKIR UDDIN; WHITE, JASON; YATES, CLAYTON; AUKERMAN, ANDREW; VANGURI, RAMI; BAREJA, ROHAN; LENCI, ROMINA; FARRÉ, PAULA LUCIA; DE SIERVI, ADRIANA; NÁPOLES, ANNA MARÍA; VOHRA, NASREEN; GARDNER, KEVIN

Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival

Communications Biology; Año: 2021 vol. 4 p. 1 - 13

FARRÉ, PAULA LUCÍA; DUCA, ROCÍO BELÉN; MASSILLO, CINTIA; DALTON, GUILLERMO NICOLÁS; GRAÑA, KAREN DANIELA; GARDNER, KEVIN; LACUNZA, EZEQUIEL; DE SIERVI, ADRIANA

Mir-106b-5p: A master regulator of potential biomarkers for breast cancer aggressiveness and prognosis

International Journal of Molecular Sciences; Año: 2021 vol. 22

DUCA RB; MASSILLO CL; DALTON GN; FARRÉ PL; GRAÑA K; GARDNER K; DE SIERVI A

MiR-19b-3p and miR-101-3p as potential biomarkers for prostate cancer diagnosis and prognosis

American Journal of Cancer Research; Año: 2021

BYUN JS; SINGHAL SK; PARK S; YI DI; YAN T; CABAN A; JONES A; MUKHOPADHYAY P; GIL SM; HEWITT SM; NEWMAN L; DAVIS MB; JENKINS BD; SEPULVEDA JL; DE SIERVI A; NÁPOLES AM; VOHRA NA; GARDNER K

Racial Differences in the Association Between Luminal Master Regulator Gene Expression Levels and Breast Cancer Survival

CLINICAL CANCER RESEARCH; Año: 2020 vol. 26 p. 1905 - 1914

MASSILLO, CINTIA; DUCA, ROCÍO BELÉN; LACUNZA, EZEQUIEL; DALTON, GUILLERMO NICOLÁS; FARRÉ, PAULA LUCÍA; TAHA, NICOLÁS; PICCIONI, FLAVIA; SCALISE, GEORGINA DANIELA; GARDNER, KEVIN; DE SIERVI, ADRIANA

Adipose tissue from metabolic syndrome mice induces an aberrant miRNA signature highly relevant in prostate cancer development

MOLECULAR ONCOLOGY; Año: 2020 vol. 14 p. 2868 - 2883

MASSILLO C; DALTON GN; PORRETTI J; SCALISE G; FARRÉ PL; PICCIONI F; SECCHIARI F; PASCUALI N; CLYNE C; GARDNER K; DE LUCA P; DE SIERVI A

CTBP1/CYP19A1/estradiol axis together with adipose tissue impacts over prostate cancer growth associated to metabolic syndrome

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Año: 2019 vol. 144 p. 1115 - 1127

BYUN JS; PARK S; YI DI; SHIN JH; HERNANDEZ SG; HEWITT SM; NICKLAUS MC; PEACH ML; GUASCH L; TANG B; WAKEFIELD LM; YAN T; CABAN A; JONES A; KABBOUT M; VOHRA NA; NÁPOLES AM; SINGHAL SK; YANCEY R; DE SIERVI A; GARDNER K

Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein

Cell death & disease; Año: 2019 vol. 10

GÓMEZ-ELÍAS MD; RAINERO CÁCERES TS; GIACCAGLI MM; GUAZZONE VA; DALTON GN; DE SIERVI A; CUASNICÚ PS; COHEN DJ; DA ROS VG

Association between high-fat diet feeding and male fertility in high reproductive performance mice

Scientific Reports; Año: 2019 vol. 9

DALTON, GUILLERMO NICOLÁS; MASSILLO, CINTIA; SCALISE, GEORGINA DANIELA; DUCA, ROCÍO; PORRETTI, JULIANA; FARRÉ, PAULA LUCIA; GARDNER, KEVIN; PAEZ, ALEJANDRA; GUERON, GERALDINE; DE LUCA, PAOLA; DE SIERVI, ADRIANA

CTBP1 depletion on prostate tumors deregulates miRNA/mRNA expression and impairs cancer progression in metabolic syndrome mice

Cell Death and Disease; Año: 2019 vol. 10

FARRÉ PL; SCALISE G; DUCA RB; DALTON N; MASSILLO CL; PORRETTI J; GRAÑA K; GARDNER K; DE LUCA P; DE SIERVI A

CTBP1 and metabolic syndrome induce an mRNA and miRNA expression profile critical for breast cancer progression and metastasis

Oncotarget; Año: 2018 vol. 9 p. 13848 - 13858

PORRETTI, JULIANA; DALTON, GUILLERMO N.; MASSILLO, CINTIA; SCALISE, GEORGINA D.; FARRÉ, PAULA L.; ELBLE, RANDOLPH; GEREZ, ESTHER N.; ACCIALINI, PAULA; CABANILLAS, ANA M.; GARDNER, KEVIN; DE LUCA, PAOLA; DE SIERVI, ADRIANA

CLCA2 epigenetic regulation by CTBP1, HDACs, ZEB1, EP300 and miR-196b-5p impacts prostate cancer cell adhesion and EMT in metabolic syndrome disease

INTERNATIONAL JOURNAL OF CANCER. JOURNAL INTERNATIONAL DU CANCER.; Lugar: New York; Año: 2018 vol. 143 p. 897 - 906

MASSILLO CL; DALTON N; FARRÉ PL; DE LUCA P; DE SIERVI A; DE SIERVI A

Implications of microRNA dysregulation in the development of prostate cancer

REPRODUCTION; Lugar: Bristol; Año: 2017 vol. 154 p. 84 - 97

LEONARDI D; ABBATE M; RICCHERI C; NUÑEZ M; ALFONSO G; GUERON G; DE SIERVI A; VAZQUEZ ES; COTIGNOLA J

Improving risk stratification of patients with childhood acute lymphoblastic leukemia: Glutathione-S-Transferases polymorphisms are associated with increased risk of relapse

Oncotarget; Año: 2017 vol. 8 p. 110 - 117

DE LUCA P; DE SIERVI A

Critical role for BRCA1 expression as a marker of chemosensitivity response and prognosis

FRONTIERS IN BIOSCIENCE-LANDMARK; Lugar: Albertson, NY, USA; Año: 2016 vol. 8 p. 72 - 83

DE LUCA P; DALTON N; SCALISE G; MOIOLA CP; PORRETTI J; MASSILLO CL; KORDON E; GARDNER K; ZALAZAR F; FLUMIAN C; TODARO L; VAZQUEZ ES; MEISS R; DE SIERVI A

CtBP1 associates metabolic syndrome and breast carcinogenesis targeting multiple miRNAs.

Oncotarget; Año: 2016 vol. 7 p. 18798 - 18811

LABANCA E; DE LUCA P; GUERON G; PAEZ A; MOIOLA CP; PORRETTI J; GIUDICE J; ZALAZAR F; NAVONE N; VAZQUEZ ES; DE SIERVI A

Association of HO-1 and BRCA1 is Critical for the Maintenance of Cellular Homeostasis in Prostate Cancer.

MOLECULAR CANCER RESEARCH; Lugar: Philadelphia; Año: 2015 vol. 13 p. 1455 - 1464

ZALAZAR F; DE LUCA P; GARDNER K; FIGG WD; MEISS R; SPALLANZANI RG; VALLECORSA P; ELGUERO B; COTIGNOLA J; VAZQUEZ ES; DE SIERVI A

Low doses of CPS49 and flavopiridol combination as potential treatment for advanced prostate cancer.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY; Lugar: Oak Park; Año: 2015 vol. 16 p. 553 - 563

MOIOLA CP; DE LUCA P; ZALAZAR F; COTIGNOLA J; RODRÍGUEZ-SEGUÍ SA; GARDNER K; MEISS R; VALLECORSA P; PIGNATARO O; MAZZA O; VAZQUEZ ES; DE SIERVI A

Prostate tumor growth is impaired by CtBP1 depletion in high fat diet fed mice.

CLINICAL CANCER RESEARCH; Año: 2014 vol. 1 p. 4086 - 4095

DE LUCA P; MOIOLA CP; ZALAZAR F; GARDNER K; VAZQUEZ ES; DE SIERVI A.

BRCA1 and p53 regulate critical prostate cancer pathways.

PROSTATE CANCER AND PROSTATIC DISEASES; Lugar: Londres; Año: 2013 vol. 16 p. 233 - 238

FERRANDO M; WAN X; MEISS R; YANG J; DE SIERVI A; NAVONE N; VAZQUEZ E

Heme Oxygenase-1 (HO-1) Expression in Prostate Cancer Cells Modulates the Oxidative Response in Bone Cells.

PLOS ONE; Lugar: San Francisco; Año: 2013 vol. 8 p. 1 - 14

PALM T; HEMMER K; WINTER J; FRICKE IB; TARBASHEVICH K; SADEGHI SHAKIB F; RUDOLPH IM; HILLJE AL; DE LUCA P; BAHNASSAWY L; MADEL R; VIEL T; DE SIERVI A; JACOBS AH; DIEDERICHS S; SCHWAMBORN JC.

A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop.

NUCLEIC ACIDS RESEARCH; Lugar: Oxford; Año: 2013 vol. 41 p. 3699 - 3712

COTIGNOLA J; LEONARDI D; SHAHABI A; ACUÑA A; STERN M; NAVONE N; SCORTICATI C; DE SIERVI A; MAZZA O; VAZQUEZ E

Glutathione-S-transferase (GST) polymorphisms are associated with relapse after radical prostatectomy.

PROSTATE CANCER AND PROSTATIC DISEASES; Lugar: Londres; Año: 2013 vol. 16 p. 28 - 34

ELGUERO B; GUERON G; GIUDICE J; TOSCANI M; DE LUCA P; ZALAZAR F; COLUCCIO-LESKOW F; MEISS R; NAVONE N; DE SIERVI A; VAZQUEZ E

Unveiling the Association of STAT3 and HO-1 in Prostate Cancer: Role beyond Heme Degradation

NEOPLASIA; Lugar: confirmar; Año: 2012 vol. 14 p. 1043 - 1056

MOIOLA C; DE LUCA P; COTIGNOLA J; GARDNER K; VAZQUEZ E; DE SIERVI A

Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY : INTERNATIONAL JOURNAL OF EXPERIMENTAL CELLULAR PHYSIOLOGY, BIOCHEMISTRY, AND PHARMACOLOGY.; Lugar: Basel; Año: 2012 vol. 30 p. 596 - 608

GUERON G; DE SIERVI A; VAZQUEZ E

ADVANCED PROSTATE CANCER: REINFORCING THE STRINGS BETWEEN INFLAMMATION AND THE METASTATIC BEHAVIOUR

PROSTATE CANCER AND PROSTATIC DISEASES; Año: 2012 vol. 64

DE LUCA P; VAZQUEZ E; MOIOLA C; ZALAZAR F; COTIGNOLA J; GUERON G; GARDNER K; DE SIERVI A

BRCA1 loss induces GADD153-mediated doxorubicin resistance in prostate cancer.

MOLECULAR CANCER RESEARCH; Año: 2011 vol. 9 p. 1078 - 1090

FERRANDO M; GUERON G; ELGUERO B; GIUDICE J; SALLES A; COLLUCCIO-LESKOW F; JARES-ERIJMAN E.A.; COLOMBO L; MEISS R; NAVONE N; DE SIERVI A; VAZQUEZ E

Heme oxygenase 1 (HO-1) challenges the angiogenic switch in prostate cancer.

ANGIOGENESIS; Año: 2011 vol. 14 p. 467 - 479

GUERON G; DE SIERVI A; VAZQUEZ E

Key Questions in Metastasis: New Insights in Molecular Pathways and Therapeutic Implications.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY; Año: 2011 vol. 12 p. 1 - 14

MOIOLA C; DE LUCA P; GARDNER K; VAZQUEZ E; DE SIERVI A

Cyclin T1 overexpression induces malignant transformation and tumor growth

CELL CYCLE; Año: 2010 vol. 9 p. 3119 - 3126

DE SIERVI A; DE LUCA P; BYUN JS; DI LJ; FUFA T; HAGGERTY CM; VAZQUEZ E; MOIOLA C; LONGO D; GARDNER K

Transcriptional autoregulation by BRCA1.

CANCER RESEARCH; Año: 2010 vol. 70 p. 532 - 542

DI LJ; FERNANDEZ AG; DE SIERVI A; LONGO D; GARDNER K

Transcriptional regulation of BRCA1 expression by a metabolic switch.

NATURE STRUCTURAL & MOLECULAR BIOLOGY; Año: 2010 vol. 17 p. 1406 - 1413

DE SIERVI A; DE LUCA P; MOIOLA C; GUERON G; TONGBAI R; CHANDRAMOULI GV; HAGGERTY C; PETERSEN DW; KAWASAKI E; KIL WJ; CAMPAHAUSEN K; LONGO D; GARDNER K

Identification of new Rel/NFkappaB regulatory networks by focused genome location analysis.

CELL CYCLE; Año: 2009 vol. 8 p. 2093 - 2100

BYUN JS; WONG MM; CUI W; IDELMAN G; LI Q; DE SIERVI A; BILKE S; HAGGERTY CM; PLAYER A; WANG YH; THIRMAN MJ; KABERLEIN JJ; PETROVAS C; KOUP RA; LONGO D; OZATO K; GARDNER K

Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2009 vol. 106 p. 18286 - 19291

GUERON G; DE SIERVI A; FERRANDO M; SALIERNO M; DE LUCA P; ELGUERO B; MEISS R; NAVONE N; VAZQUEZ E

Critical Role of Endogenous Heme Oxygenase 1 as a Tuner of the Invasive Potential of Prostate Cancer Cells

MOLECULAR CANCER RESEARCH; Año: 2009 vol. 7 p. 1745 - 1755

MACIAS E; MILIANI DE MARVAL PL; DE SIERVI A; CONTI CJ; SENDEROWICZ AM; RODRIGUEZ-PUEBLA ML

CDK2 activation in mouse epidermis induces keratinocyte proliferation but does not affect skin tumor development.

AMERICAN JOURNAL OF PATHOLOGY; Año: 2008 vol. 173 p. 526 - 535

GE Y; BYUN JS; DE LUCA P; GUERON G; LI QQ; YABE IM; SADIQ-ALI SG; FIGG WD; QUINTERO J; HAGGERTY CM; DE SIERVI A; GARDNER K

Combinatorial anti-leukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide CPS49 and flavopiridol.

MOLECULAR PHARMACOLOGY; Año: 2008 vol. 74 p. 872 - 883

SMITH J; FEEBERN WJ; COLLINS I; DE SIERVI A; MONTANO I; HAGGERTY CM; MCNUTT MC; BUTSCHER WG; DZEKUNOVA I; PETERSEN DW; KAWASAKI E; MERCHANT JL; GARDNER K

Kinetic profiles of p300 occupancy in vivo predict common features of promoter structure and coactivator recruitment.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2004 vol. 101 p. 11554 - 11559

DE SIERVI A; MARINISSEN M; DIGGS J; WANG XF; PAGES G; SENDEROWICZ AM

Transcriptional activation of p21(waf1/cip1) by alkylphospholipids: role of the mitogen-activated protein kinase pathway in the transactivation of the human p21(waf1/cip1) promoter by Sp1.

CANCER RESEARCH; Año: 2004 vol. 64 p. 743 - 750

FACCHINETTI MM; DE SIERVI A; TOSKOS D; SENDEROWICZ AM

UCN-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway.

CANCER RESEARCH; Año: 2004 vol. 64 p. 3629 - 3637

PARERA VE; DE SIERVI A; VARELA L; ROSSETTI MV; BATLLE AMC

Acute porphyrias in the Argentinean population: a review.

CELLULAR AND MOLECULAR BIOLOGY; Año: 2003 vol. 49 p. 493 - 500

LAHUSEN T; DE SIERVI A; KUNICK C; SENDEROWICZ AM

Alsterpaullone, a novel cyclin-dependent kinase inhibitor, induces apoptosis by activation of caspase-9 due to perturbation in mitochondrial membrane potential.

MOLECULAR CARCINOGENESIS.; Año: 2003 vol. 36 p. 183 - 194

DE SIERVI A; VAZQUEZ E; REZAVAL C; ROSSETTI MV; BATLLE AMC

Delta-aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines.

BIOMED CENTRAL CANCER; Año: 2002 vol. 2 p. 1 - 6

DE SIERVI A; VARELA L; PARERA V; BATLLE AMC; ROSSETTI MV

Diagnosis of latent acute intermittent porphyria by genetic analysis.

ANNALS OF CLINICAL BIOCHEMISTRY; Año: 2001 vol. 38 p. 149 - 152

DE SIERVI A; VARELA L; PARERA V; BATLLE AMC; ROSSETTI MV

Diagnosis of latent acute intermittent porphyria by genetic analysis.

ANNALS OF CLINICAL BIOCHEMISTRY; Año: 2001 vol. 38 p. 149 - 152

MENDEZ M; ROSSETTI MV; DE SIERVI A; BATLLE AMC; PARERA V

Mutations in familial porphyria cutanea tarda: two novel and two previously described for hepatoerythropoietic porphyria.

HUMAN MUTATION; Lugar: New York; Año: 2000 vol. 16 p. 269 - 270

DE SIERVI A; WEISS CÁDIZ DE; PARERA VE; BATLLE AMC; ROSSETTI MV.

Identification and characterization of two novel mutations that produce Acute Intermittent Porphyria: a 3 base deletion (841-843delGGA) and a missense mutation (T35M).

HUMAN MUTATION; Lugar: New York; Año: 2000 vol. 370 p. 1 - 5

DE SIERVI A; PARERA V; VARELA L; BATLLE AMC; ROSSETTI MV

A novel mutation (1320InsT) identified in two Argentine families with variegate porphyria

HUMAN MUTATION; Lugar: New York; Año: 2000 p. 1 - 2

DE SIERVI A; PARERA V; BATLLE AMC; ROSSETTI MV

Two new mutations (H106P and L178V) in the protoporphyrinogen oxidase gene in Argentineanpatients with variegate porphyria

HUMAN MUTATION; Año: 2000 vol. 181 p. 1 - 3

DE SIERVI A; ROSSETTI MV; PARERA V; ASTRIN KH; AIZENCANG GI; GLASS IA; BATLLE AMC; DESNICK RJ

Identification and characterization of hydroxymethylbilane synthase mutations causing acute intermittent porphyria: evidence for an ancestral founder of the common G111R mutation.

AMERICAN JOURNAL OF MEDICAL GENETICS; Año: 1999 vol. 86 p. 366 - 375

DE SIERVI A; ROSSETTI MV; PARERA V; MENDEZ M; VARELA L; BATLLE AMC

Acute intermittent porphyria: biochemical and clinical analysis in the Argentinean population.

CLINICA CHIMICA ACTA; Año: 1999 vol. 288 p. 63 - 71

DE SIERVI A; MENDEZ M; PARERA V; VARELA L; BATLLE AMC; ROSSETTI MV

Acute intermittent porphyria: characterization of two novel mutations in the porphobilinogen deaminase gene, one amino acid deletion (453-455delAGC) and one splicing aceptor site mutation (IVS8-1G>T).

HUMAN MUTATION; Año: 1999 vol. 14 p. 1 - 5

DE SIERVI A; ROSSETTI MV; LEZAMA D; BATLLE AMC

Porphyrin Biosynthesis in Normal and Haem Mutants of Saccharomyces cerevisiae. Studies on the Inheritance of the HEM R+ Phenotype.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART B, BIOCHEMISTRY & MOLECULAR BIOLOGY.; Año: 1996 vol. 115 p. 167 - 173