INVESTIGADORES
LEONARDI Dario
artículos
REAL, DANIEL A.; GAGLIANO, AILEN; ORZAN, LUCAS; LEONARDI, DARÍO; SALOMON, CLAUDIO J.
Amorphous solid dispersions of triclabendazole: Keeping the supersaturated drug solution using poloxamers
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY; Año: 2024 vol. 91
TEJADA, GUILLERMO; CALVO, NATALIA L.; MORRI, MAURO; SORTINO, MAXIMILIANO; LAMAS, CELINA; ÁLVAREZ, VERA A.; LEONARDI, DARÍO
Miconazole Nitrate Microparticles in Lidocaine Loaded Films as a Treatment for Oropharyngeal Candidiasis
Materials; Año: 2023 vol. 16
OPERTO, MARÍA ALEJANDRA; MAGGIO, RUBÉN; LEONARDI, DARÍO; VIGNADUZZO, SILVANA
Flexible New Dosage Forms Containing Carvedilol for the Treatment of Patients with Cardiovascular Disorders: Development, Stability, Palatability, and Microbiological Studies
AAPS PHARMSCITECH; Año: 2023 vol. 24
ANDRÉS REAL, DANIEL; GAGLIANO, AILEN; SONSINI, NAHUEL; WICKY, GASPAR; ORZAN, LUCAS; LEONARDI, DARÍO; SALOMON, CLAUDIO
Design and optimization of pH-sensitive Eudragit nanoparticles for improved oral delivery of triclabendazole
INTERNATIONAL JOURNAL OF PHARMACEUTICS; Año: 2022 vol. 617
PAULINO, ÉRICA TEX; RIBEIRO DE LIMA, MONIQUE; VIÇOSA, ALESSANDRA LIFSITCH; SILVA, CLEBER HOOPER DA; SALOMON, CLAUDIO JAVIER; REAL, DANIEL ANDRÉS; LEONARDI, DARIO; MELLO SILVA, CLÉLIA CHRISTINA; MORAES NETO, ANTONIO HENRIQUE ALMEIDA DE
The Effect of Different Formulations of Praziquantel in Reducing Worms in the Prepatent Period of Schistosomiasis in Murine Models
Frontiers in Public Health; Año: 2022 vol. 10
CALVO, NATALIA L.; TEJADA, GUILLERMO; SVETAZ, LAURA A.; QUIROGA, ARIEL D.; ALVAREZ, VERA A.; LAMAS, MARÍA C.; LEONARDI, DARÍO
Development and optimization of a new tioconazole vaginal mucoadhesive film using an experimental design strategy. Physicochemical and biological characterization
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS; Año: 2021 vol. 205
CODINA, ANA V.; PRIOTTI, JOSEFINA; LEONARDI, DARÍO; VASCONI, MARÍA D.; LAMAS, MARÍA C.; HINRICHSEN, LUCILA I.
Effect of sex and genotype of the host on the anthelmintic efficacy of albendazole microcrystals, in the CBi-IGE Trichinella infection murine model
PARASITOLOGY; Año: 2021 vol. 148 p. 1545 - 1553
REAL, DANIEL A.; HOFFMANN, STEFAN; LEONARDI, DARÍO; GOYCOOLEA, FRANCISCO M.; SALOMON, CLAUDIO J.
A quality by design approach for optimization of Lecithin/Span® 80 based nanoemulsions loaded with hydrophobic drugs
JOURNAL OF MOLECULAR LIQUIDS; Año: 2021 vol. 321
VINAUD, MARINA CLAIRE; REAL, DANIEL; FRAGA, CAROLINA MIGUEL; LIMA, NAYANA F; SOUZA LINO JUNIOR, RUY DE; LEONARDI, DARÍO; J SALOMON, CLAUDIO
Nanodelivery of nitazoxanide: impact on the metabolism of Taenia crassiceps cysticerci intracranially inoculated in mice
Therapeutic Delivery; Año: 2020 vol. 11 p. 329 - 339
MORRI, MAURO; CASABONNE, CECILIA; LEONARDI, DARÍO; VIGNADUZZO, SILVANA
Orphan Formulations for Pediatric Use: Development and Stability Control of Two Sildenafil Citrate Solutions for the Treatment of Pulmonary Hypertension
AAPS PHARMSCITECH; Lugar: Berlin; Año: 2020 vol. 21
REAL, DANIEL; ORZAN, LUCAS; LEONARDI, DARÍO; SALOMON, CLAUDIO J.
Improving the Dissolution of Triclabendazole from Stable Crystalline Solid Dispersions Formulated for Oral Delivery
AAPS PHARMSCITECH; Año: 2020 vol. 21
CODINA, ANA V.; PRIOTTI, JOSEFINA; LEONARDI, DARÍO; VASCONI, MARÍA D.; HINRICHSEN, LUCILA I.; LAMAS, MARÍA C.
Effect of Genotype and Sex of the Host on the Bioavailability of Novel Albendazole Microcrystals Based on Chitosan and Cellulose Derivatives
AAPS PHARMSCITECH; Año: 2020 vol. 21
BARRERA, MARÍA G.; TEJADA, GUILLERMO; LEONARDI, DARÍO; LAMAS, MARÍA C.; SALOMÓN, CLAUDIO J.
A Novel Prototype Device for Microencapsulation of Benznidazole: In Vitro/In Vivo Studies
AAPS PHARMSCITECH; Año: 2020 vol. 21
BUCHTER, VALENTIN; PRIOTTI, JOSEFINA; LEONARDI, DARÍO; LAMAS, MARÍA C.; KEISER, JENNIFER
Preparation, Physicochemical Characterization and In Vitro and In Vivo Activity Against Heligmosomoides polygyrus of Novel Oral Formulations of Albendazole and Mebendazole
JOURNAL OF PHARMACEUTICAL SCIENCES; Lugar: New York; Año: 2020 vol. 109 p. 1819 - 1826
TEJADA, G.; BARRERA, M.G.; GARCÍA, P.; SORTINO, M.; LAMAS, M.C.; LASSALLE, V.; ALVAREZ, V.; LEONARDI, D.
Nanoparticulated Systems Based on Natural Polymers Loaded with Miconazole Nitrate and Lidocaine for the Treatment of Topical Candidiasis
AAPS PHARMSCITECH; Año: 2020 vol. 21
GARCÍA, AGUSTINA; PRIOTTI, JOSEFINA; CODINA, ANA VICTORIA; VASCONI, MARÍA DELIA; QUIROGA, ARIEL D.; HINRICHSEN, LUCILA I.; LEONARDI, DARIO; LAMAS, MARÍA CELINA
Synthesis and characterization of a new cyclodextrin derivative with improved properties to design oral dosage forms
Drug Delivery and Translational Research; Año: 2019 vol. 9 p. 273 - 278
CALVO, NATALIA L.; ALVAREZ, VERA A.; LAMAS, MARÍA C.; LEONARDI, DARÍO
New approaches to identification and characterization of tioconazole in raw material and in pharmaceutical dosage forms
Journal of Pharmaceutical Analysis; Año: 2019 vol. 9 p. 40 - 48
CALVO, NATALIA L.; SVETAZ, LAURA A.; ALVAREZ, VERA A.; QUIROGA, ARIEL D.; LAMAS, MARÍA C.; LEONARDI, DARÍO
Chitosan-hydroxypropyl methylcellulose tioconazole films: A promising alternative dosage form for the treatment of vaginal candidiasis
INTERNATIONAL JOURNAL OF PHARMACEUTICS; Lugar: Amsterdam; Año: 2019 vol. 556 p. 181 - 191
CALVO, NATALIA L.; SREEKUMAR, SRUTHI; SVETAZ, LAURA A.; LAMAS, MARÍA C.; MOERSCHBACHER, BRUNO M.; LEONARDI, DARÍO
Design and Characterization of Chitosan Nanoformulations for the Delivery of Antifungal Agents
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; Año: 2019 vol. 20
TEJADA, G.; LAMAS, M.C.; SVETAZ, L.; SALOMÓN, C.J.; ALVAREZ, V.A.; LEONARDI, D.
Effect of drug incorporation technique and polymer combination on the performance of biopolymeric antifungal buccal films
INTERNATIONAL JOURNAL OF PHARMACEUTICS; Año: 2018 vol. 548 p. 431 - 442
TEJADA, G.; LAMAS, M. C.; SORTINO, M.; ALVAREZ, V. A.; LEONARDI, D.
Composite Microparticles Based on Natural Mucoadhesive Polymers with Promising Structural Properties to Protect and Improve the Antifungal Activity of Miconazole Nitrate
AAPS PHARMSCITECH; Año: 2018
PRIOTTI, JOSEFINA; LEONARDI, DARÍO; PICO, GUILLERMO; LAMAS, MARÍA C.
Application of Fluorescence Emission for Characterization of Albendazole and Ricobendazole Micellar Systems: Elucidation of the Molecular Mechanism of Drug Solubilization Process
AAPS PHARMSCITECH; Año: 2018 vol. 19 p. 1152 - 1159
REAL, DANIEL; HOFFMANN, STEFAN; LEONARDI, DARÍO; SALOMON, CLAUDIO; GOYCOOLEA, FRANCISCO M.
Chitosan-based nanodelivery systems applied to the development of novel triclabendazole formulations
PLOS ONE; Lugar: San Francisco; Año: 2018 vol. 13
ORLANDI, SILVINA; PRIOTTI, JOSEFINA; DIOGO, HERMÍNIO P.; LEONARDI, DARIO; SALOMON, CLAUDIO J.; NUNES, TERESA G.
Structural Elucidation of Poloxamer 237 and Poloxamer 237/Praziquantel Solid Dispersions: Impact of Poly(Vinylpyrrolidone) over Drug Recrystallization and Dissolution
AAPS PHARMSCITECH; Año: 2018
MORRI, M.; CASTELLANO, P.; LEONARDI, D.; VIGNADUZZO, S.
First Development, Optimization, and Stability Control of a Pediatric Oral Atenolol Formulation
AAPS PHARMSCITECH; Lugar: Berlin; Año: 2018 vol. 19 p. 1781 - 1788
REAL, DANIEL; LEONARDI, DARÍO; WILLIAMS, ROBERT O.; REPKA, MICHAEL A.; SALOMON, CLAUDIO J.
Solving the Delivery Problems of Triclabendazole Using Cyclodextrins
AAPS PHARMSCITECH; Lugar: Berlin; Año: 2018
PRIOTTI, J.; GARCÍA, A.; LEONARDI, D.; FERREIRA, M.J.; LAMAS, M.C.; NUNES, T.G.
Succinyl-β-cyclodextrin: Influence of the substitution degree on albendazole inclusion complexes probed by NMR
MATERIALS SCIENCE & ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS; Año: 2018 vol. 92 p. 694 - 702
PRIOTTI, JOSEFINA; BAGLIONI, MARÍA VIRGINIA; GARCÍA, AGUSTINA; RICO, MARÍA JOSÉ; LEONARDI, DARÍO; LAMAS, MARÍA CELINA; MÁRQUEZ, MAURICIO MENACHO
Repositioning of Anti-parasitic Drugs in Cyclodextrin Inclusion Complexes for Treatment of Triple-Negative Breast Cancer
AAPS PHARMSCITECH; Lugar: Berlin; Año: 2018
TEJADA, G.; PICCIRILLI, G.N.; SORTINO, M.; SALOMÓN, C.J.; LAMAS, M.C.; LEONARDI, D.
Formulation and in-vitro efficacy of antifungal mucoadhesive polymeric matrices for the delivery of miconazole nitrate
MATERIALS SCIENCE & ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS; Año: 2017 vol. 79 p. 140 - 150
PRIOTTI, J.; CODINA A.V.; LEONARDI, D.; VASCONI M.D.; HINRICHSEN, L.I.; LAMAS, M.C.
Albendazole Microcrystal Formulations Based on Chitosan and Cellulose Derivatives: Physicochemical Characterization and In Vitro Parasiticidal Activity in Trichinella spiralis Adult Worms
AAPS PHARMSCITECH; Año: 2017 vol. 18 p. 947 - 956
TEJADA, G.; BARRERA M. G; PICCIRILLI, G.N.; SORTINO, M.; FRATTINI, A.; SALOMON, C.J.; LAMAS, M.C:; LEONARDI, D.
Development and evaluation of buccal films based on chitosan for the potential treatment of oral candidiasis
AAPS PHARMSCITECH; Lugar: Berlin; Año: 2017 vol. 18 p. 936 - 946
SANTOS, HIGO ; REAL, DANIEL; LEONARDI, DARÍO; ROCHA, SANDRA CARLA; ALONSO, VICTORIA; SERRA, ESTEBAN; SILBER, ARIEL MARIANO; SALOMON, CLAUDIO JAVIER
Development and in-vitro/in-vivo evaluation of a novel benznidazole liquid dosage form using a quality-by-design approach
TROPICAL MEDICINE AND INTERNATIONAL HEALTH; Año: 2017
COSTA, E.; PRIOTTI, J.; ORLANDI, S.; LEONARDI, D.; LAMAS, M.C.; NUNEZ, T.; DIOGO, H.P.; SALOMON, C.J.; FERREIRA, M.
Unexpected solvent impact in the crystallinity of praziquantel/poly (vinylpyrrolidone) formulations. A solubility, DSC and solid-state NMR study
INTERNATIONAL JOURNAL OF PHARMACEUTICS; Lugar: Amsterdam; Año: 2016 vol. 5 p. 983 - 993
GARCÍA, A.; LEONARDI, D.; LAMAS, M.C.
Promising applications in drug delivery systems of a novel b-cyclodextrin derivative obtained by green synthesis
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; Lugar: Amsterdam; Año: 2016 vol. 26 p. 602 - 608
CODINA A.V.; GARCÍA A.; LEONARDI D.; VASCONI M.D.; DI MASSO R.J.; LAMAS M.C.; HINRICHSEN L.I.
Efficacy of albendazole:b-cyclodextrin citrate in the parenteral stage of Trichinella spiralis infection
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES; Lugar: Amsterdam; Año: 2015
GARCIA, A.; LEONARDI, D.; PICCIRILLI, G.N.; MAMPRIN, M.; OLIVIERI, A.C.; LAMAS, M.C.
Spray drying formulation of albendazole microspheres by experimental design. In vitro?in vivo studies
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY; Lugar: Londres; Año: 2015 p. 244 - 252
PRIOTTI J.; FERREIRA M.; LAMAS M.C.; LEONARDI D; SALOMON C.J.; NUNEZ T.
First solid-state NMR spectroscopy evaluation of complexes of benznidazole with cyclodextrin derivatives
CARBOHYDRATE POLYMERS; Lugar: Amsterdam; Año: 2015 p. 90 - 97
FERREIRA M.; GARCÍA A; LEONARDI D; SALOMON CJ; LAMAS M.C.; NUNEZ T
13C and15N solid-state NMR studies on albendazole and cyclodextrin albendazole complexes
CARBOHYDRATE POLYMERS; Lugar: Amsterdam; Año: 2015 vol. 123 p. 130 - 135
GARCIA, A.; LEONARDI, D.; SALAZAR, M.; LAMAS, M. C.
Modified b-Cyclodextrin Inclusion Complex to Improve the Physicochemical Properties of Albendazole. Complete In Vitro Evaluation and Characterization
PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 1 - 8
GARCÍA, A.; LEONARDI, D.; VASCONI, M.D.; HINRICHSEN, L.I.; LAMAS, M. C.
Characterization of Albendazole-Randomly Methylated-b-Cyclodextrin Inclusion Complex and In Vivo Evaluation of Its Antihelmitic Activity in a Murine Model of Trichinellosis
PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 1 - 7
PICCIRILLI, G.N.; GARCÍA, A.; LEONARDI, D.; MAMPRIN, M.; BOLMARO, R. E.; SALOMÓN, C. J.; LAMAS M.C.
Chitosan microparticles: influence of the gelation process on the release profile and oral bioavailability of albendazole, a class II compound
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY; Lugar: Londres; Año: 2014 p. 1476 - 1482
LEONARDI, D.; BOMBARDIERE, M.E.; SALOMON, C.J.
Effects of benznidazole:cyclodextrin complexes on the drugbioavailability upon oral administration to rats
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES; Lugar: Amsterdam; Año: 2013 vol. 62 p. 543 - 548
SPAMPINATO C.; LEONARDI D.
Candida Infections, Causes, Targets, and Resistance Mechanisms: Traditional and Alternative Antifungal Agents
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY; Lugar: New York; Año: 2013 vol. 2013 p. 1 - 13
REAL, D.; MARTINEZ, M.V.; FRATTINI, A.; SOAZO, M.; LUQUE, A.G.; BIASOLI, M.S.; SALOMON, C.J.; OLIVIERI, A.C.; LEONARDI, D.
Design, characterization and in vitro evaluation of antifungal polymeric films
AAPS PHARMSCITECH; Año: 2013 vol. 14 p. 64 - 73
LEONARDI D.; SALOMON C.J.
Unexpected Performance of Physical Mixtures over Solid Dispersions on the Dissolution Behavior of Benznidazole from Tablets
JOURNAL OF PHARMACEUTICAL SCIENCES; Año: 2013 vol. 102 p. 1016 - 1023
SPAMPINATO C.; LEONARDI D.
Molecular Fingerprints to Identify Candida Species
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY; Lugar: New York; Año: 2013 vol. 2013 p. 1 - 10
GARCÍA, A.; BARRERA M. G; PICCIRILLI, G.N.; VASCONI, M.D.; DI MASSO, R.J.; LEONARDI, D.; HINRICHSEN, L.I.; LAMAS, M.C.
Novel albendazole formulations given during the intestinal phase of Trichinella spiralis infection reduce effectively parasitic muscle burden in mice
PARASITOLOGY INTERNATIONAL; Lugar: Amsterdam; Año: 2013 p. 568 - 570
SOARES DA CUNHA FILHO M.S.; LIRA DE SÁ-BARRETO L.C.; LEONARDI D.; LAMAS M.C.; SALOMON C.J.
Recentes avanços no tratamento da doença de Chagas
BRASILIA MEDICA; Año: 2012 vol. 49 p. 279 - 283
LAMAS, M. C.; LEONARDI, D.; LAMBRI, O.; BOLMARO, R.E.; BASSANI, G.; BARRERA, M.G.; SALOMÓN, C.J.
Preparation, characterization and dissolution studies of fast release diclofenac sodium tablets from PVP solid dispersions
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY; Lugar: New York; Año: 2010 vol. 15 p. 162 - 168
BARRERA, M. G.; LEONARDI, D.; BOLMARO, R. E.; ECHENIQUE, C. G.; OLIVIERI, A. C.; SALOMÓN, C. J.; LAMAS, M. C.
In vivo evaluation of albendazole microspheres for the treatment of Toxocara canis larva migrans
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS; Año: 2010 vol. 75 p. 451 - 454
LEONARDI, D.; SALOMÓN, C. J.
Influence of Water Uptake, Gel Network, and Disintegration Time on Prednisone Release from Encapsulated Solid Dispersions
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY; Lugar: New York; Año: 2010 vol. 15 p. 184 - 191
LEONARDI, D.; SALOMÓN, C. J.; LAMAS, M. C.; OLIVIERI, A. C.
Development of novel formulations for Chagas? disease. Optimization of benznidazol chitosan microparticles based on artificial neural networks.
INTERNATIONAL JOURNAL OF PHARMACEUTICS; Lugar: Amsterdan; Año: 2009 vol. 367 p. 140 - 147
LEONARDI, D.; ECHENIQUE, C. G.; LAMAS, M. C.; SALOMÓN, C. J.
High efficacy of albendazole?PEG 6000 in the treatment of Toxocara canis larva migrans infection
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY; Lugar: oxford; Año: 2009 vol. 64 p. 375 - 378
LEONARDI, D.; LAMAS, M.C.; OLIVIERI, A.C.
Multiresponse optimization of the properties of albendazole?chitosan microparticles
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS; Año: 2008 vol. 48 p. 802 - 807
LEONARDI, D.; BARRERA, M. G.; LAMAS, M. C.; SALOMÓN, C. J.
Development of Prednisone-PEG 6000 Fast-release Tablets from Solid Dispersions: Solid-state Characterization, Dissolution Behavior and Formulation Parameters.
AAPS PHARMSCI; Lugar: Arlington; Año: 2007 vol. 8 p. 221 - 228
LAMAS, M.; VILLAGGI, L.; NOCITO, I.; BASSANI, G.; LEONARDI, D.; PASCUTTI, F.; SERRA, E.; SALOMÓN, C.
Development of parenteral formulations and evaluation of the biological activity of the trypanocide drug benznidazole
INTERNATIONAL JOURNAL OF PHARMACEUTICS; Año: 2006 vol. 307 p. 239 - 243
LEONARDI D.; DI SAPIO O. A; GATTUSO M. A; GATTUSO S. J
Caracteres morfoanatomicos de la corteza y hojas de Tabebuia impetiginosa y T. Heptaphylla
BOLETíN DE LA SOCIEDAD ARGENTINA DE BOTáNICA; Año: 2002 vol. 37 p. 51 - 61