Effects of the Synthetic Estrogen 17α-Ethinylestradiol on Aromatase Expression, Reproductive Behavior and Sperm Quality in the Fish Jenynsia multidentata.

ROGGIO, A.; GUYÓN, N.F.; HUED, A. C.; AMÉ, M. V.; VALDÉS, M.E.; GIOJALAS, L.; WUNDERLIN D.A.; BISTONI, M.A.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

SPRINGER

Lugar: Berlin; Año: 2014 vol. 92 p. 579 - 584

0007-4861

The synthetic estrogen 17a-ethynylestradiol(EE2) has been increasingly detected in sewage effluents inthe last two decades. The aim of the present study wasdetermined if EE2 exposure adversely affected reproductionin internally fertilizing fish species Jenynsia multidentata.Sexual behavior, brain and gonadal aromataseexpression as well as sperm quality were evaluated. Thebrain aromatase expression, reproductive behavior, spermatozoaviability and gonadosomatic index were sensitivebiomarkers of EE2 effects on this species. The conditionfactor, hepatosomatic index, gonadal aromatase expression,sperm count and sperm velocities were unaltered after EE2exposure. The present work highlights the importance ofusing a combination of several biomarkers to study theeffects of estrogenic compounds, especially when trying tolink these results to potential population-level effects.