Efficacy of Panax ginseng extract combined with cephalexin as a dry cow therapy

BECCARIA, C.; BARAVALLE, C.; SILVESTRINI, P.; RENNA, M.S.; MOLINERI, A.I.; SIGNORINI, M.L.; NEDER, V.E.; SUÁREZ-ARCHILLA, G.; CALVINHO, L.F.; DALLARD, B.

Journal of Dairy Research

CAMBRIDGE UNIV PRESS

Lugar: Cambridge; Año: 2021

0022-0299

Our objective was to evaluate the efficacy of intramammary administration, at drying-off, of aPanax ginseng extract (PGe) combined with cephalexin (Ceph) on the post-calving bacteriologicalcure rate of pre-existing intramammary infections (IMI) and on the occurrence of newIMI during the dry period. In addition, milk yield and somatic cell count (SCC) in the posttreatmentlactation were evaluated. One hundred and eight late-lactation cows were randomlydivided into two experimental groups and were treated at drying-off with Ceph alone or PGecombined with Ceph. Cure rates for IMI present at drying-off were similar for both treatments(OR = 0.95, 95% CI = 0.33?2.74). Cure rates for Staphylococcus aureus were lower (OR = 15.4,95% CI = 1.66?142.52) in quarters treated with PGe + Ceph than in those treated with Cephalone. Intramammary infusion of PGe + Ceph at drying-off had no effect on preventing newdry period IMI (OR = 0.75, 95% CI = 0.38?1.51), compared with infusion of Ceph alone. Milkproduction and SCC in the ensuing lactation were not affected by PGe + Ceph treatment. Inconclusion, addition of PGe to dry cow therapy did not show any advantage over the use ofdry cow therapy alone.