ZURITA, ADOLFO; VEGA HISSI, ESTEBAN; CIANCI ROMERO, AGOSTINA; LUJÁN, ADELA MARÍA; SALIDO, SOFÍA; YANEFF, AGUSTÍN; DAVIO, CARLOS; COBO, JUSTO; CARPINELLA, MARÍA CECILIA; ENRIZ, RICARDO DANIEL

Rosmarinic Acid Present in Lepechinia floribunda and Lepechinia meyenii as a Potent Inhibitor of the Adenylyl Cyclase gNC1 from Giardia lamblia

Plants; Año: 2024 vol. 13

SAHORES, ANA; GONZÁLEZ, ANGELA RODRÍGUEZ; YANEFF, AGUSTÍN; MAY, MARÍA; GÓMEZ, NATALIA; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA; DAVIO, CARLOS; SHAYO, CARINA

Ceefourin-1, a MRP4/ABCC4 inhibitor, induces apoptosis in AML cells enhanced by histamine

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Año: 2023 vol. 1867

ROSENBERG, MARÍA LUCÍA; YANEFF, AGUSTÍN; FERRADÁS, GONZALO MANUEL; VILLAFAÑE TAPIA, MARGARITA PAZ; DAVIO, CARLOS ALBERTO; GOETTE, NORA PAULA; VLACHOVSKY, SANDRA GABRIELA; PERONI, ROXANA NOEMÍ; ODDO, ELISABET MÓNICA; AZURMENDI, PABLO JAVIER

Total and Extracellular Vesicle cAMP Contents in Urine Are Associated with Autosomal Dominant Polycystic Kidney Disease (ADPKD) Progression

Life; Año: 2023 vol. 13

RODRÍGUEZ GONZÁLEZ, ANGELA; SAHORES, ANA; DÍAZ?NEBREDA, ANTONELA; YANEFF, AGUSTÍN; DI SIERVI, NICOLÁS; GÓMEZ, NATALIA; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA; DAVIO, CARLOS; SHAYO, CARINA

MRP4/ABCC4 expression is regulated by histamine in acute myeloid leukemia cells, determining cAMP efflux

FEBS JOURNAL; Año: 2021

BURGHI, VALERIA; ECHEVERRÍA, EMILIANA B.; ZAPPIA, CARLOS D.; DÍAZ NEBREDA, ANTONELA; RIPOLL, SONIA; GÓMEZ, NATALIA; SHAYO, CARINA; DAVIO, CARLOS A.; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA C.

Biased agonism at histamine H1 receptor: Desensitization, internalization and MAPK activation triggered by antihistamines

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2021 vol. 896

VEGA HISSI, ESTEBAN GABRIEL; DE COSTA GUARDAMAGNA, ANTONELLA BELEN; GARRO, ADRIANA D.; FALCON, CRISTIAN R.; ANDERLUH, MARKO; TOMA?I?, TIHOMIR; KIKELJ, DANIJEL; YANEFF, AGUSTÍN; DAVIO, CARLOS A.; ENRIZ, RICARDO D.; ZURITA, ADOLFO R.

Discovery of a New Potent N‐(piperidin‐4‐yl)‐1H‐pyrrole‐2‐carboxamide Inhibitor of Adenylyl Cyclase of G. lamblia. Biological Evaluation and Molecular Modeling Studies

CHEMMEDCHEM; Año: 2021

ECHEVERRÍA, EMILIANA; CABRERA, MAIA; BURGHI, VALERIA; SOSA, MÁXIMO; RIPOLL, SONIA; YANEFF, AGUSTÍN; MONCZOR, FEDERICO; DAVIO, CARLOS; SHAYO, CARINA; FERNÁNDEZ, NATALIA

The Regulator of G Protein Signaling Homologous Domain of G Protein-Coupled Receptor Kinase 2 Mediates Short-Term Desensitization of β3-Adrenergic Receptor

Frontiers in Pharmacology; Año: 2020 vol. 11

CHIARANTE, NICOLÁS; ALONSO, CARLOS A. I.; PLAZA, JESSICA; LOTTERO-LECONTE, RAQUEL; ARROYO-SALVO, CAMILA; YANEFF, AGUSTÍN; OSYCKA-SALUT, CLAUDIA E.; DAVIO, CARLOS; MIRAGAYA, MARCELO; PEREZ-MARTINEZ, SILVINA

Cyclic AMP efflux through MRP4 regulates actin dynamics signalling pathway and sperm motility in bovines

Scientific Reports; Año: 2020 vol. 10

MCCARTHY, CLARA INÉS; CHOU-FREED, CAMBRIA; RODRÍGUEZ, SILVIA SUSANA; YANEFF, AGUSTÍN; DAVIO, CARLOS; RAINGO, JESICA

Constitutive activity of dopamine receptor type 1 (D1R) increases CaV2.2 currents in PFC neurons

JOURNAL OF GENERAL PHYSIOLOGY; Lugar: New York; Año: 2020 vol. 152

ALBERTONI BORGHESE, MARÍA FLORENCIA; ORTIZ, MARÍA DEL CARMEN; MARINONI, ROCÍO C.; ORONEL, LUCAS H.; PALAMIDESSI, MILENA; YARZA, CAROLINA A.; DI SIERVI, NICOLÁS; DAVIO, CARLOS; MAJOWICZ, MÓNICA P.

Inhibition of Endothelin system during the postnatal nephrogenic period in the rat. Its relationship with hypertension and renal disease in adulthood

PLOS ONE; Año: 2020 vol. 15

GARGIULO, LUCÍA; RIVERO, EZEQUIEL MARIANO; DI SIERVI, NICOLÁS; BUZZI, EDGARDO DAVID; BUFFONE, MARIANO GABRIEL; DAVIO, CARLOS ALBERTO; LÜTHY, ISABEL ALICIA; BRUZZONE, ARIANA

Agonist Effects of Propranolol on Non-Tumor Human Breast Cells

Cells; Año: 2020 vol. 9

COLAVITA, JUAN PABLO MELANA; TODARO, JUAN SANTIAGO; DE SOUSA, MAXIMILIANO; MAY, MARÍA; GÓMEZ, NATALIA; YANEFF, AGUSTIN; DI SIERVI, NICOLAS; AGUIRRE, MARÍA VICTORIA; GUIJAS, CARLOS; FERRINI, LEANDRO; DAVIO, CARLOS; RODRÍGUEZ, JUAN PABLO

Multidrug resistance protein 4 (MRP4/ABCC4) is overexpressed in clear cell renal cell carcinoma (ccRCC) and is essential to regulate cell proliferation

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES; Año: 2020 vol. 161 p. 836 - 847

OSYCKA-SALUT, C.E.; MARTÍNEZ-LEÓN, E.; GERVASI, M.G.; CASTELLANO, L.; DAVIO, C.; CHIARANTE, N.; FRANCHI, A.M.; RIBEIRO, M.L.; DÍAZ, E.S.; PEREZ-MARTINEZ, S.

Fibronectin induces capacitation-associated events through the endocannabinoid system in bull sperm

THERIOGENOLOGY; Año: 2020 vol. 153 p. 91 - 101

SAHORES, A.; CAROZZO, A.; MAY, M.; GÓMEZ, N.; DI SIERVI, N.; DE SOUSA SERRO, M.; YANEFF, A.; RODRÍGUEZ-GONZÁLEZ, A.; ABBA, M.; SHAYO, C.; DAVIO, C.

Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness

Scientific Reports; Año: 2020 vol. 10

ZAPPIA, CARLOS D.; SOTO, ARIADNA; GRANJA?GALEANO, GINA; FENOY, IGNACIO; FERNANDEZ, NATALIA; DAVIO, CARLOS A.; SHAYO, CARINA; FITZSIMONS, CARLOS P.; GOLDMAN, ALEJANDRA; MONCZOR, FEDERICO

Azelastine potentiates antiasthmatic dexamethasone effect on a murine asthma model

Pharmacology Research & Perspectives; Lugar: NY; Año: 2019 vol. 7

ECHEVERRÍA, EMILIANA; RUEDA, ANA JULIA VELEZ; CABRERA, MAIA; JURITZ, EZEQUIEL; BURGHI, VALERIA; FABIÁN, LUCAS; DAVIO, CARLOS; MENNA, PABLO LORENZANO; FERNÁNDEZ, NATALIA CRISTINA

Identification of inhibitors of the RGS homology domain of GRK2 by docking-based virtual screening

LIFE SCIENCES; Lugar: Amsterdam; Año: 2019

GENTILE, EMILIANO ALBERTO; CASTRONUOVO, CYNTHIA CECILIA; CUESTAS, MARÍA LUJÁN; GÓMEZ, NATALIA; DAVIO, CARLOS; OUBIÑA, JOSÉ RAÚL; MATHET, VERÓNICA LIDIA

F127 poloxamer effect on cytotoxicity induction of tumour cell cultures treated with doxorubicin

JOURNAL OF PHARMACY AND PHARMACOLOGY; Año: 2019

YANEFF, AGUSTÍN; SAHORES, ANA; GOMEZ, NATALIA; CAROZZO, ALEJANDRO; SHAYO, CARINA; DAVIO, CARLOS

MRP4/ABCC4 as a new therapeutic target: meta-analysis to determine cAMP binding sites as a tool for drug design

CURRENT MEDICINAL CHEMISTRY.; Año: 2019 vol. 25

CAROZZO, ALEJANDRO; YANEFF, AGUSTÍN; GÓMEZ, NATALIA; DI SIERVI, NICOLÁS; SAHORES, ANA; DIEZ, FEDERICO; ATTORRESI, ALEJANDRA I.; RODRÍGUEZ-GONZÁLEZ, ÁNGELA; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA; ABBA, MARTÍN; SHAYO, CARINA; DAVIO, CARLOS

Identification of MRP4/ABCC4 as a Target for Reducing the Proliferation of Pancreatic Ductal Adenocarcinoma Cells by Modulating the cAMP Efflux

Molecular pharmacology; Año: 2019 vol. 96 p. 13 - 25

DÍAZ NEBREDA, ANTONELA; ZAPPIA, CARLOS DANIEL; RODRÍGUEZ GONZÁLEZ, ANGELA; SAHORES, ANA; SOSA, MÁXIMO; BURGHI, VALERIA; MONCZOR, FEDERICO; DAVIO, CARLOS; FERNÁNDEZ, NATALIA; SHAYO, CARINA

Involvement of histamine H 1 and H 2 receptor inverse agonists in receptor's crossregulation

EUROPEAN JOURNAL OF PHARMACOLOGY; Año: 2019 p. 42 - 52

BURGHI, VALERIA; ECHEVERRÍA, EMILIANA B.; SOSA, MÁXIMO H.; QUIROGA, DIEGO T.; MUÑOZ, MARINA C.; DAVIO, CARLOS; MONCZOR, FEDERICO; FERNÁNDEZ, NATALIA C.; DOMINICI, FERNANDO P.

Participation of gai-adenylate cyclase and ERK1/2 in mas receptor signaling pathways

Frontiers in Pharmacology; Año: 2019 vol. 10

AMABLE, GASTÓN; MARTÍNEZ-LEÓN, EDUARDO; PICCO, MARÍA ELISA; DI SIERVI, NICOLAS; DAVIO, CARLOS; ROZENGURT, ENRIQUE; REY, OSVALDO

Metformin inhibits β-catenin phosphorylation on Ser-552 through an AMPK/PI3K/Akt pathway in colorectal cancer cells

INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELLULAR BIOLOGY; Año: 2019 vol. 112 p. 88 - 94

ANDERMATTEN, ROMINA BELÉN; CIRIACI, NADIA; SCHUCK, VIRGINIA SOLEDAD; DI SIERVI, NICOLÁS; RAZORI, MARÍA VALERIA; MISZCZUK, GISEL SABRINA; MEDEOT, ANABELA CAROLINA; DAVIO, CARLOS ALBERTO; CROCENZI, FERNANDO ARIEL; ROMA, MARCELO GABRIEL; BAROSSO, ISMAEL RICARDO; SÁNCHEZ POZZI, ENRIQUE JUAN

Sphingosine 1-phosphate receptor 2/adenylyl cyclase/protein kinase A pathway is involved in taurolithocholate-induced internalization of Abcc2 in rats

ARCHIVES OF TOXICOLOGY.; Año: 2019

ALONSO, C. A. I.; LOTTERO-LECONTE, R.; LUQUE, G. M.; VERNAZ, Z. J.; DI SIERVI, N.; GERVASI, M. G.; BUFFONE, M. G.; DAVIO, C.; PEREZ-MARTINEZ, S.

MRP4-mediated cAMP efflux is essential for mouse spermatozoa capacitation

JOURNAL OF CELL SCIENCE; Año: 2019 vol. 132

CAMICIA, FEDERICO; CELENTANO, ANA M.; JOHNS, MALCOLM E.; CHAN, JOHN D.; MALDONADO, LUCAS; VACA, HUGO; DI SIERVI, NICOLÁS; KAMENTEZKY, LAURA; GAMO, ANA M.; ORTEGA-GUTIERREZ, SILVIA; MARTIN-FONTECHA, MAR; DAVIO, CARLOS; MARCHANT, JONATHAN S.; ROSENZVIT, MARA C.

Unique pharmacological properties of serotonergic G-protein coupled receptors from cestodes

PLOS NEGLECTED TROPICAL DISEASES; Lugar: San Francisco; Año: 2018 vol. 12

ALBERTONI BORGHESE, MARIA FLORENCIA; HOPE, SANDRA; ORTIZ, MARIA DEL CARMEN; BARCHUK, MAGALÍ; KESSLER, CAMILA; DAVIO, CARLOS; VATTA, MARCELO; MAJOWICZ, MÓNICA

Altered expression of Aquaporin-2 in one-kidney, one-clip hypertension

LIFE SCIENCES; Lugar: Amsterdam; Año: 2018 vol. 208 p. 72 - 78

CABRERA MAIA; ECHEVERRIA EMILIANA; REMES LENICOV FEDERICO; CARDAMA GEORGINA; GONZALEZ NAZARENO; DAVIO CARLOS; FERNANDEZ NATALIA; LORENZANO MENNA PABLO

Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines

ONCOTARGET; Lugar: New York; Año: 2017

MONCZOR FEDERICO; COPSEL SABRINA; FERNANDEZ NATALIA; DAVIO CARLOS; SHAYO C

Histamine H2 Receptor in Blood Cells: A Suitable Target for the Treatment of Acute Myeloid Leukemia

Handbook of Experimental Pharmacology; Lugar: Berlin Heidelberg; Año: 2017 vol. 241 p. 141 - 160

GRANJA-GALEANO, GINA; ZAPPIA, CARLOS DANIEL; FABIÁN, LUCAS; DAVIO, CARLOS; SHAYO, CARINA; FERNÁNDEZ, NATALIA; MONCZOR, FEDERICO

Effect of mutation of Phe 243 6.44 of the histamine H 2 receptor on cimetidine and ranitidine mechanism of action

BIOCHEMICAL PHARMACOLOGY; Año: 2017

MICAELA SORDELLI; JIMENA BELTRAME; ELSA ZOTTA ; GOMEZ NATALIA; GANNA DMYTRENKO; MARIA SALES ; SANDRA BLOIS; DAVIO CARLOS; SILVINA PEREZ MARTINEZ; FRANCHI ANA MARIA; MARIA LAURA RIBEIRO

Endogenous lysophosphatidic acid participates in vascularization and decidualization at the maternal-fetal interface in the rat

REPRODUCTION FERTILITY AND DEVELOPMENT; Lugar: Collingwood; Año: 2017

AGOSTI F; CORDISCO GONZALEZ S; MARTINEZ DAMONTE V; TOLOSA MJ; DI SIERVI NICOLAS; SCHIOTH HB; DAVIO CARLOS; PERELLO M; RAINGO J

Melanocortin 4 receptor constitutive activity inhibits L-type voltage-gated calcium channels in neurons.

NEUROSCIENCE; Lugar: Amsterdam; Año: 2017 vol. 346 p. 102 - 112

GARGIULO L; MAY MARIA; RIVERO EM; COPSEL SABRINA; LAMB CAROLINA; LYDON J; DAVIO CARLOS; LANARI CLAUDIA; LUTHY I; BRUZZONE ARIANA

A Novel Effect of β-Adrenergic Receptor on Mammary Branching Morphogenesis and its Possible Implications in Breast Cancer.

JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA; Lugar: New York; Año: 2017 vol. 22 p. 43 - 57

SALAZAR, ANA IN?S; CAROZZO, ALEJANDRO; CORREA, FERNANDO; DAVIO, CARLOS; FRANCHI, ANA MAR?A

Evidence for CB2 receptor involvement in LPS-induced reduction of cAMP intracellular levels in uterine explants from pregnant mice: pathophysiological implications

MOLECULAR HUMAN REPRODUCTION.; Año: 2017 p. 1 - 9

ALONSO, CARLOS AGUST?N I.; OSYCKA-SALUT, CLAUDIA E.; CASTELLANO, LUCIANA; CESARI, ANDRE?NA; DI SIERVI, NICOL?S; MUTTO, ADRI?N; JOHANNISSON, ANDERS; MORRELL, JANE M.; DAVIO, CARLOS; PEREZ-MARTINEZ, SILVINA

Extracellular cAMP activates molecular signalling pathways associated with sperm capacitation in bovines

MOLECULAR HUMAN REPRODUCTION.; Año: 2017 p. 1 - 14

VANINA SARAULLO; DI SIERVI NICOLAS; BELEN JEREZ; DAVIO CARLOS; ZURITA ADOLFO

Synthesis and degradation of cAMP in Giardia lamblia: Possible role and characterization of a Nucleotidyl Cyclase with a single Cyclase-Homology-Domain.

BIOCHEMICAL JOURNAL; Lugar: Londres; Año: 2017

SALAZAR ANA INES; VERCELLI C; SCHIARITI, V; DAVIO CARLOS; COREA FERNANDO; FRANCHI ANA MARIA

Heparin exerts anti-apoptotic effects on uterine explants by targeting the endocannabioid system.

APOPTOSIS; Lugar: Berlin; Año: 2016 vol. 21 p. 965 - 976

ALONSO NATALIA; DIAZ NEBREDA ANTONELLA; MONCZOR FEDERICO; GUTKIND JS; DAVIO CARLOS; FERNADEZ NATALIA; SHAYO CARINA

PI3K pathway is involved in ERK signaling cascade activation by histamine H2R agonist in HEK293T cells.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Lugar: Amsterdam; Año: 2016 vol. 1860 p. 1998 - 2007

DIEGO Y. GRINMAN; LEONARDO ROMORINI; DIEGO M. PRESMAN; LUCIANA ROCHA VIEGAS; OMAR A. COSO; DAVIO CARLOS; PECCI ADALI

Role of 3'-5'-cyclic adenosine monophosphate on the epidermal growth factor dependent survival in mammary epithelial cells

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2016 vol. 419 p. 259 - 267

CABRERA MAIA; GOMEZ NATALIA; REMES LENICOV FEDERICO; ECHEVERRIA EMILIANA; SHAYO CARINA; MOGLIONI ALBERTINA; FERNADEZ NATALIA; DAVIO CARLOS

G2/M cell cycle arrest and tumor selective apoptosis of acute leukemia cells by a promising benzophenone thiosemicarbazone compound.

PLOS ONE; Lugar: San Francisco; Año: 2015

ZAPPIA DANIEL; GRANJA GALEANO GINA; FERNADEZ NATALIA; SHAYO CARINA; DAVIO CARLOS; FITZSIMONS CARLOS; MONCZOR FEDERICO

Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways.

SCIENTIFIC REPORT; Año: 2015

ALONSO NATALIA; ZAPPIA DANIEL; CABRERA MAIA; DAVIO CARLOS; SHAYO CARINA; MONCZOR FEDERICO; FERNADEZ NATALIA

Physiological implications of biased signaling at histamine H2 receptors.

Front Pharmacol; Año: 2015 vol. 6 p. 1 - 9

CAROZZO ALEJANDRO; DIEZ FEDERICO; GOMEZ NATALIA; CABRERA MAIA; SHAYO CARINA; DAVIO CARLOS; FERNADEZ NATALIA

Dual role of cAMP in the transcriptional regulation of multidrug resistance-associated protein 4 (MRP4) in pancreatic adenocarcinoma cell lines

PLOS ONE; Lugar: San Francisco; Año: 2015 vol. 10 p. 1 - 13

VENTIMIGLIA MARIA SILVIA; NAJENSON ANA CLARA; PERAZZO JC; CAROZZO ALEJANDRO; MARCELO VATTA; DAVIO CARLOS; BIANCIOTTI, LILIANA

Blockade of multidrug resistance associated proteins aggravates acute pancreatitis and blunts atrial natriuretic factor beneficial effect in rats: Role of MRP4/ABCC4.

MOLECULAR MEDICINE; Año: 2015 vol. 21 p. 58 - 67

COPSEL SABRINA; BRUZZONE ARIANA; MAY MARIA; JULIEN BEYRATH; VICTORIA WARGON; JEANNETTE CANY; FRANS G.M. RUSSEL; SHAYO CARINA; DAVIO CARLOS

Multidrug resistance protein 4/ ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia

ONCOTARGET; Lugar: New York; Año: 2014 vol. 5 p. 9308 - 9321

GARGIULO L; COPSEL SABRINA; RIVERO EM; GALES C; SENARD JM; LUTHY I; DAVIO CARLOS; BRUZZONE ARIANA

Differential β2-adrenergic receptor expression defines the phenotype of non-tumorigenic and malignant human breast cell lines

ONCOTARGET; Lugar: New York; Año: 2014 vol. 20 p. 10058 - 10069

ANDRÉS E. ZUCCHETTI; ISMAEL R. BAROSSO; ANDREA C. BOAGLIO; CECILIA L. BASIGLIO; DIEGO R. TABORDA; MARCELO G. LUQUITA; CARLOS DAVIO; MARCELO G. ROMA; FERNANDO A. CROCENZI; ENRIQUE J. SÁNCHEZ POZZI

G protein-coupled receptor30?adenylyl cyclase?protein kinase A pathway is involved in estradiol 17ß-D-glucuronide-induced cholestasis.

HEPATOLOGY (BALTIMORE, MD.); Lugar: New York; Año: 2014 vol. 59 p. 1016 - 1029

ALONSO NATALIA; MONCZOR FEDERICO; ECHEVERRIA EMILIANA; DAVIO CARLOS; SHAYO CARINA; FERNADEZ NATALIA

Signal transduction mechanism of biased ligands at histamine H2 receptors.

BIOCHEMICAL JOURNAL; Lugar: Londres; Año: 2014 vol. 459 p. 117 - 126

CLAUDIA OSYCKA SALUT; DIEZ FEDERICO; BURDET JULIANA; MARÍA GRACIA GERVASI; ANA FRANCHI; BIANCIOTTI, L; DAVIO CARLOS; SILVINA PEREZ MARTINEZ

CYCLIC AMP EFFLUX THROUGH MRPs IS CRITICAL IN THE REGULATION OF BOVINE SPERM CAPACITATION: CONTRIBUTION OF A1 ADENOSINE RECEPTORS

MOLECULAR HUMAN REPRODUCTION.; Lugar: Oxford; Año: 2014 vol. 20 p. 89 - 99

ALONSO NATALIA; FERNADEZ NATALIA; NOTCOVICH CINTIA; MONCZOR FEDERICO; SIMAAN M; BALDI ALBERTO; GUTKIND JS; DAVIO CARLOS; SHAYO CARINA

Cross-desensitization and cointernalization of H1 and H2 histamine receptors reveal new insights into histamine signal integration.

MOLECULAR PHARMACOLOGY; Lugar: Baltimore; Año: 2013 vol. 83 p. 1087 - 1098

ESPELT MV; DE TEZANOS PINTO F; ALVAREZ CL; SANCHEZ ALBERTI G; INCICCO J; LEAL DENIS MF; DAVIO CARLOS; SCHWARZBAUM PJ

On the role of ATP release, ectoATPase activity and 2 extracellular ADP in the regulatory volume decrease of 3 Huh-7 human hepatoma cells.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY; Lugar: Bethesda; Año: 2013

MONCZOR FEDERICO; FERNADEZ NATALIA; FITZSIMONS CARLOS; SHAYO CARINA; DAVIO CARLOS

Antihistaminergics and inverse agonism. Potential therapeutic applications.

EUROPEAN JOURNAL OF PHARMACOLOGY; Lugar: Amsterdam; Año: 2013

VAZQUEZ RAMIRO; RIVEIRO MARIA EUGENIA; MONDILLO CAROLINA; PERAZZO JC; VERMEULEN MONICA; BALDI ALBERTO; DAVIO CARLOS; SHAYO CARINA

Pharmacodynamic study of the 7,8-dihydroxy-4-methylcoumarin-induced selective cytotoxicity towards U-937 leukemic cells versus mature monocytes: cytoplasmic p21Cip1/WAF1 as resistance factor.

BIOCHEMICAL PHARMACOLOGY; Lugar: Amsterdam; Año: 2013 vol. 82 p. 210 - 221

OLIVIERI LEDA; DAVIO CARLOS; BATLLE ALCIRA; GEREZ ESTHER

ALAS-1 gene expression is down-regulated by Akt-mediated phosphorylation and nuclear exclusion of FOXO1 by vanadate in diabetic mice.

BIOCHEMICAL JOURNAL; Lugar: Londres; Año: 2012 vol. 442 p. 303 - 310

VAZQUEZ RAMIRO; RIVEIRO MARIA EUGENIA; VERMEULEN MONICA; MONDILLO CAROLINA; PHILIP H. COOMBES; NEAL CROUCH; FATHIMA ISMAIL; DULCIE A. MULHOLLAND; ALBERTO BALDI; SHAYO CARINA; DAVIO CARLOS

Toddaculin, a natural coumarin from Toddalia asiatica, induces differentiation and apoptosis through different signaling pathways in U-937 leukemic cells.

PHYTOMEDICINE; Año: 2012 vol. 19 p. 737 - 746

CAROLINA SALIS; DAVIO CARLOS; VANINA USACH; NICOLAS URTASUN; BELEN GOITIA; ROCIO, MARTINEZ VIVOT; JUANA M PASQUINI; PATRICIA SETTON-AVRUJ

Iron and holotransferrin induce cAMP-dependent differentiation of Schwann cells.

NEUROCHEMISTRY INTERNATIONAL; Lugar: Amsterdam; Año: 2012 vol. 61 p. 798 - 806

VAZQUEZ RAMIRO; RIVEIRO MARIA EUGENIA; VERMEULEN MONICA; ALONSO ELIANA; MONDILLO CAROLINA; GOMEZ NATALIA; FACORRO GRACIELA; PIEHL LIDIA; MOGLIONI ALBERTINA; FERNANDEZ NATALIA; BALDI ALBERTO; SHAYO CARINA; DAVIO CARLOS

Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2012 vol. 20 p. 5537 - 5549

REMES LENICOV, F; RODRIGUEZ RODRIGUES, C.; SABATTÉ, J; CABRINI, M.; JANCIC, C.; OSTROWSKI, M.; MERLOTI, A.; GONZALEZ, H.; DONALDSON, M; PASQUALINI, R.S; DAVIO CARLOS; GEFFNER, J; CEBALLOS, A

Semen promotes the differentiation of tolerogenic dendritic cells.

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2012 vol. 189 p. 4777 - 4786

COPSEL SABRINA; GARCIA CORINA; DIEZ FEDERICO; VERMEULEN MONICA; BALDI ALBERTO; LILIANA BIANCIOTTI; RUSSEL FG; SHAYO CARINA; DAVIO CARLOS

Multidrug Resistance Protein 4 (MRP4/ABCC4) regulates cAMP cellular levels and controls human leukemia cell proliferation and differentiation.

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2011 vol. 286 p. 6979 - 6988

MIRYAM RODRIGUEZ; DIEZ FEDERICO; VENTIMIGLIA MS; MORALES VP; MARCELO VATTA; DAVIO CARLOS; BIANCIOTTI, L

Atrial natriuretic factor stimulates cAMP efflux in the rat exocrine pancreas through Multidrug Resistance Associated Proteins.

GASTROENTEROLOGY; Lugar: 140(4): 1292-1302, ; Año: 2011 vol. 104 p. 1292 - 1302

FERNADEZ NATALIA; GOTARDO FEDERICO; ALONSO NATALIA; MONCZOR FEDERICO; SHAYO CARINA; CARLOS DAVIO

Roles of phosphorylation dependent and independent mechanisms in the regulation of Histamine H2 receptor by G Protein-coupled Receptor Kinase

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2011 vol. 286 p. 28697 - 28706

VENTIMIGLIA MS; MIRYAM RODRIGUEZ; MORALES VP; ELVERDIN JC; PERAZZO JC; CASTANEDA MM; DAVIO CARLOS; MARCELO VATTA; LILIANA BIANCIOTTI

Endothelins participate in the central and peripheral regulation of submandibular gland secretion in the rat.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY, INTEGRATIVE AND COMPARATIVE PHYSIOLOGY; Año: 2011 vol. 300 p. 109 - 120

GOMEZ NATALIA; DIEGO SANTOS; VAZQUEZ RAMIRO; LEOPOLDO SUESCUN; ÁLVARO MOMBRÚ; VERMEULEN MONICA; LILIANA FINKIELSZTEIN; CARINA SHAYO; MOGLIONI ALBERTINA; DINORA GAMBINO; CARLOS DAVIO

Synthesis, structural characterization and proapoptotic activity of 1-indanone thiosemicarbazones platinum (II) and palladium (II) complexes: Potential role as selective antileukemic agents

CHEMMEDCHEM; Lugar: Weinheim; Año: 2011 vol. 6 p. 1485 - 1494

NOTCOVICH CINTIA; DIEZ FEDERICO; TUBIO MARIA ROSARIO; BALDI ALBERTO; KAZANIETZ MG; DAVIO CARLOS; SHAYO CARINA

Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways

EXPERIMENTAL CELL RESEARCH; Año: 2010 vol. 316 p. 401 - 411

RIVEIRO MARIA EUGENIA; DE KIMPE NORBERT; MOGLIONI ALBERTINA; VAZQUEZ RAMIRO; MONCZOR FEDERICO; SHAYO CARINA; DAVIO CARLOS

Coumarins: old compounds with novel promising therapeutic perspectives.

CURRENT MEDICINAL CHEMISTRY.; Año: 2010 vol. 17 p. 1325 - 1338

TUBIO MARIA ROSARIO; FERNADEZ NATALIA; FITZSIMONS CARLOS; COPSEL SABRINA; SANTIAGO SERGIO; SHAYO CARINA; DAVIO CARLOS; MONCZOR FEDERICO

Expression of a G protein-coupled receptor (GPCR) leads to attenuation of signaling by other GPCRs: experimental evidence for a spontaneous GPCR constitutive inactive form.

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2010 vol. 285 p. 14990 - 14998

RIVEIRO MARIA EUGENIA; DOMINICK MAES; VAZQUEZ RAMIRO; VERMEULEN MONICA; SVEN MANGELINCKX; JAN JACOVS; SILVIA DEBENEDETTI; CARINA SHAYO; DE KIMPE NORBERT; DAVIO CARLOS

Towards establishing structure-activity relationships for oxygenated coumarins as differentiation inducers of promonocytic leukemic cells.

BIOORGANIC & MEDICINAL CHEMISTRY.; Año: 2009 vol. 17 p. 6547 - 6559

FERNANDEZ NATALIA; MONCZOR FEDERICO; BALDI ALBERTO; DAVIO CARLOS; SHAYO CARINA

1. Histamine H2 receptor trafficking: Role of arrestin, dynamin and clathrin in H2r internalization

MOLECULAR PHARMACOLOGY; Lugar: Bethesda, MD 20814-3995 - USA; Año: 2008 vol. 74 p. 1109 - 1118

VENTIMIGLIA MS; MIRYAM RODRIGUEZ; ELVERDIN JC; DAVIO CARLOS; VATTA, M; BIANCIOTTI, L

Atrial natriuretic factor intracellular signaling in the rat submandibular gland.

REGULATORY PEPTIDES; Año: 2008 vol. 150 p. 43 - 49

RIVEIRO MARIA EUGENIA; VAZQUEZ RAMIRO; MOGLIONI ALBERTINA; GOMEZ NATALIA; BALDI ALBERTO; DAVIO CARLOS; SHAYO CARINA

Biochemical mechanisms underlying the pro-apoptotic activity of 7,8-dihidroxy-4-methylcoumarin in human leukemic cells.

BIOCHEMICAL PHARMACOLOGY; Año: 2008 vol. 75 p. 725 - 736

MAES DOMINICK; RIVEIRO MARIA EUGENIA; SHAYO CARINA; DAVIO CARLOS; SILVIA DEBENEDETTI,; DE KIMPE NORBERT

Total synthesis of naturally occurring 5,6,7- and 5,7,8-trioxygenated coumarins.

TETRAHEDRON; Lugar: Amsterdam; Año: 2008 vol. 64 p. 4438 - 4443

RIVEIRO MARIA EUGENIA; MOGLIONI ALBERTINA; VAZQUEZ RAMIRO; GOMEZ NATALIA; PIEHL LIDIA; FACORRO GRACIELA; RUBIN DE CELIS EMILIO; SHAYO CARINA; DAVIO CARLOS

Structural insights into hydroxycoumarins-induced apoptosis in U-937 cells

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: Amsterdam; Año: 2008 vol. 16 p. 2665 - 2675

NATALIA FERNANDEZ; FEDERICO MONCZOR; MARIA ROSARIO TUBIO; CARINA SHAYO; CARLOS DAVIO

Regulatory mechanisms underlying GKR2 levels in U937 cells. Evidence for GRK3 involvement.

BIOCHEMICAL PHARMACOLOGY; Lugar: Amsterdam; Año: 2007 vol. 73 p. 1758 - 1767

MARIA EUGENIA SABATTINI; MIRYAM RODRIGUEZ; MARIA MEATRIZ DI CARLO; DAVIO CARLOS; MARCELO VATTA; LILIANA BIANCIOTTI

C-type natriuretic peptide enhances amylase release through NPR-C receptors in the exocrine pancreas

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Lugar: Bethesda; Año: 2007 vol. 293 p. 987 - 994

AMARAL M; DAVIO CARLOS; CEBALLOS A; SALAMONE G; CANONES C

Histamine improves antigen uptake and cross-presentation by dendritic cells.

JOURNAL OF IMMUNOLOGY; Lugar: Bethesda; Año: 2007 vol. 179 p. 3425 - 3433

FEDERICO MONCZOR; NATALIA FERNANDEZ; EUGENIA RIVEIRO; ALEJANDRO MLADOVAN; ALBERTO BALDI; CARINA SHAYO; CARLOS DAVIO

Histamine H2 receptor overexpression induces U937 cell differentiation despite triggered mechanisms to attenuate cAMP signalling

BIOCHEMICAL PHARMACOLOGY; Lugar: Amsterdam; Año: 2006 vol. 71 p. 1219 - 1228

SABBATINI, ME; VATTA, M; DAVIO, C; BIANCIOTTI, L

Atrial natriuretic factor negatively modulates secretin intracellular signaling

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY; Lugar: Bethesda; Año: 2006 vol. 292 p. 349 - 357

DOMINICK MAES,; STIJN VERVISCH,; SILVIA DEBENEDETTI,; CARLOS DAVIO,; SVEN MANGELINCKX,; NICOLA GIUBELLINA; NORBERT DE KIMPE

Synthesis and structural revision of naturally occurring ayapin derivatives

TETRAHEDRON; Lugar: Amsterdam; Año: 2005 vol. 61 p. 2505 - 2511

RIVEIRO MARIA EUGENIA; SHAYO CARINA; MONCZOR FEDERICO; FERNANDEZ NATALIA; BALDI ALBERTO; DE KIMPE NORBERT; ROSSI J; SILVIA DEBENEDETTI,; DAVIO CARLOS

Induction of cell differentiation in human leukemia U-937 cells by 5-oxygenated-6,7-methylenedioxycoumarins from Pterocaulon polystachyum.

CANCER LETTERS; Lugar: Amsterdam; Año: 2004 vol. 210 p. 179 - 188

SHAYO CARINA; LEGNAZZI B; MONCZOR FEDERICO; FERNANDEZ NATALIA; RIVEIRO MARIA EUGENIA; BALDI ALBERTO; DAVIO CARLOS

The time-course of cyclic AMP signaling is critical for leukemia U-937 cell differentiation.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Lugar: Amsterdam; Año: 2004 vol. 314 p. 798 - 804

GARCIA CORINA; PAEZ PABLO; DAVIO CARLOS; SOTO EDUARDO; PASQUINI JUANA MARIA

Apotransferrin induces cAMP/CREB pathway and cell cycle exit in immature oligodendroglial cells.

JOURNAL OF NEUROSCIENCE RESEARCH; Lugar: New York; Año: 2004 vol. 78 p. 338 - 346

PAEZ PABLO; GARCIA CORINA; DAVIO CARLOS; CAMPAGNONI AT; SOTO EDUARDO; PASQUINI JUANA MARIA

Apotransferrin promotes the differentiation of two oligodendroglial cell lines.

GLIA; Lugar: New York; Año: 2004 vol. 46 p. 207 - 217

FITZSIMONS CARLOS; MONCZOR FEDERICO; FERNANDEZ NATALIA; SHAYO CARINA; DAVIO CARLOS

Mepyramine, a histamine H1 receptor inverse agonist, binds preferentially to a G protein-coupled form of the receptor and sequesters G protein.

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2004 vol. 279 p. 34431 - 34439

MONCZOR FEDERICO; FERNADEZ NATALIA; LEMOS LEGNAZZI BIBIANA; RIVEIRO MARIA EUGENIA; BALDI ALBERTO; SHAYO CARINA; DAVIO CARLOS

Tiotidine, a histamine H2 receptor inverse agonist that binds with high affinity to an inactive G-protein-coupled form of the receptor. Experimental support for the cubic ternary complex model.

MOLECULAR PHARMACOLOGY; Lugar: Baltimore; Año: 2003 vol. 64 p. 512 - 520

SHAYO CARINA; FERNADEZ NATALIA; LEMOS LEGNAZZI BIBIANA; MONCZOR FEDERICO; MLADOVAN AEJANDRO; BALDI ALBERTO; DAVIO CARLOS

Histamine H2 receptor desensitization: involvement of a select array of G protein-coupled receptor kinases.

MOLECULAR PHARMACOLOGY; Lugar: Baltimore; Año: 2001 vol. 60 p. 1049 - 1056

SHAYO CARINA; DAVIO CARLOS; BRODSKY ANDRES; MLADOVAN AEJANDRO; LEMOS LEGNAZZI BIBIANA; RIVERA ELENA; BALDI ALBERTO

Histamine modulates the expression of c-fos through cyclic AMP production via the H2 receptor in the human promonocytic cell line U937.

MOLECULAR PHARMACOLOGY; Lugar: Baltimore; Año: 1997 vol. 51 p. 983 - 990