GIUSTI SA,; PINO NS,; PANNUNZIO C, ; OGANDO, MORA B.; ARMANDO N; GARRET L; ZIMPRICH A; BECKER L ; GIMENO ML; LUKIN J; MERINO F; PARDI MB; PEDRONCINI, OLIVIA; DI MAURO GC; GAILUS DURNER V; FUCHS H; HRABE DE ANGELIS M; PATOP IL; TURCK CW; DEUSSING JM,; VOGT WEISENHORN DM; JAHN O; KADENER S; HOELTER SM, ; BROSE N, ; GIESERT F; WURST W; MARIN-BURGIN A; REFOJO D,

A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli

Science Advances; Año: 2024

WIGHTMAN FF; LUKIN J; GIUSTI SA; SOUTSCHEK M; BRAGADO L; POZZI B; PIERELLI ML; GONZÁLEZ P; FEDEDA JP; SCHRATT G; FUJIWARA R; WILUSZ JE; REFOJO D,; DE LA MATA M,

Influence of RNA circularity on Target RNA-Directed MicroRNA Degradation

Nucleic Acid Research; Año: 2024

MUFFELS I; SCHENE IF; REHMANN H; MASSINK MPG; VAN DER WAL MM; BAUDER C; LABEUR M,; ARMANDO N; LEQUIN MH; HOUBEN ML; HAITJEMA S; HUISMAN A; VANSENNE F; BLUVSTEIN J; PAPPAS J; SHAILEE LB; ZARATE YI; MOKRY M; VAN HAAFTEN G; NIEUWENHUIS EES; REFOJO D,; V. WIJK F; FUCHS SA; VAN HASSELT P

Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated lymphopenia and neurodegeneration

AMERICAN JOURNAL OF HUMAN GENETICS; Lugar: United States; Año: 2023

SZALAI, ALAN M.; SIARRY, BRUNO; LUKIN, JERÓNIMO; WILLIAMSON, DAVID J.; UNSAIN, NICOLÁS; CÁCERES, ALFREDO; PILO-PAIS, MAURICIO; ACUNA, GUILLERMO; REFOJO, DAMIÁN; OWEN, DYLAN M.; SIMONCELLI, SABRINA; STEFANI, FERNANDO D.

Three-dimensional total-internal reflection fluorescence nanoscopy with nanometric axial resolution by photometric localization of single molecules

NATURE COMMUNICATIONS; Año: 2021 vol. 12

SZALAI, ALAN M.; SIARRY, BRUNO; LUKIN, JERÓNIMO; GIUSTI, SEBASTIÁN; UNSAIN, NICOLÁS; CÁCERES, ALFREDO; STEINER, FLORIAN; TINNEFELD, PHILIP; REFOJO, DAMIÁN; JOVIN, THOMAS M.; STEFANI, FERNANDO D.

Super-resolution Imaging of Energy Transfer by Intensity-Based STED-FRET

NANO LETTERS (PRINT); Año: 2021 vol. 21 p. 2296 - 2303

OGANDO, MORA B.; PEDRONCINI, OLIVIA; FEDERMAN, NOEL; ROMANO, SEBASTIÁN A.; BRUM, LUCIANO A.; LANUZA, GUILLERMO M.; REFOJO, DAMIAN; MARIN-BURGIN, ANTONIA

Cholinergic modulation of dentate gyrus processing through dynamic reconfiguration of inhibitory circuits

Cell Reports; Año: 2021 vol. 36

VOGL AM,; PUH L,; BECERRA R; GIUSTI SA,; VERSCHUEREN E,; HINKLE TB,; BORDENAVE MD,; ADRIAN M,; HEIDERSBACH A,; YANKILEVICH P,; STEFANI FD,; WURST W,; HOOGENRAAD; KIRKPATRICK DS,; REFOJO D,; SHENG M,

Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics.

Nature Structural and Molecular Biology; Año: 2020

LIBERMAN, ANA CLARA; TRIAS, EMILIANO; DA SILVA CHAGAS, LUANA; TRINDADE, PABLO; DOS SANTOS PEREIRA, MARISSOL; REFOJO, DAMIAN; HEDIN-PEREIRA, CECILIA; SERFATY, CLAUDIO A.

Neuroimmune and inflammatory signals in complex disorders of the central nervous system

NEUROIMMUNOMODULATION.; Año: 2019 vol. 25 p. 246 - 270

BROCKMANN M; DÖNGI M; EINSFELDER U; KÖRBER N; REFOJO D,; STEIN V,

Neddylation regulates excitatory synaptic transmission and plasticity

Scientific Reports; Año: 2019

DEDIC N,; KUEHNE C,; JAKOVCEVSKI M,; HARTMANN J,; GENEWSKY A; GOMES KS; ANDERSHANOVA E; POEHLMANN M,; CHANG S,; KOLARZ A,; VOGL AM,; METZGER MW; SCHMIDT M; ALMADA R, ; RESSLER KJ,; WOTJAK CT,; GRINEVICH V,; CHEN A; SCHMIDT M; WURST W,; REFOJO D,; DEUSSING JM,

CRH acts anxiolytic by modulating dopamine release through a subset of GABAergic long-range projection neurons

NATURE NEUROSCIENCE.; Lugar: Londres; Año: 2018 vol. 21 p. 803 - 807

BARABAS FM; MASULLO N; BORDENAVE N; GIUSTI SA,; UNSAIN N; REFOJO D,; CACERES A; STAFANI FD

Automated quantification of protein periodic nanostructures in fluorescence nanoscopy images: abundance and regularity of neuronal spectrin membrane-associated skeleton

Scientific Reports; Año: 2017

METZGER MW; WALSER SM,; DEDIC N,; APRILE-GARCIA F,; JACUBKOVA; ADAMCZYK M; WEBB K; UHR M; REFOJO D,; SCHMIDT M; FRIESS E; STEIGER A; KIMURA M; CHEN A; HOLSBOER F; ARZT E,; WURST W,; DEUSSING JM.

Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function, sleep quality and stress vulnerability

JOURNAL OF NEUROSCIENCE; Lugar: Washington; Año: 2017

APRILE-GARCIA F,; METZGER MW; PAEZ-PEREDA M,; STADLER H; ACUÑA M,; LIBERMAN AC,; SENIN SA,; GEREZ J; HOIJMAN E; REFOJO D,; MITKOVSKI M; PANHUYSEN M; STÜHMER W; HOLSBOER F,; DEUSSING JM,; ARZT E,

Co-Expression of Wild-Type P2X7R with Gln460Arg Variant Alters Receptor Function.

PLOS ONE; Lugar: San Francisco; Año: 2016 vol. 11 p. 1 - 16

RYBAK-WOLF A; STOTTMEISTER C; GLAZAR P; JENS M; PINO NS,; GIUSTI SA,; HANAN M; BEHM M; BARTOK O; ASHWAL-FLUSS R; HERZOG M; SCHREYER L; PAPAVASILEIOU P; IVANOV O; ÖHMAN M; REFOJO D,; KADENER S; RAJEWSKY N

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

MOLECULAR CELL; Lugar: United States; Año: 2015

VOGL AM,; BROCKMANN M; GIUSTI SA,; MACCARRONE G; VERCELLI CA,; BAUDER C; RICHTER J; ROSELLI F; HAFFNER S; DEDIC N,; WOTJAK CT; VOGT-WEISENHORN DM, ; CHOQUET D; TURCK CW; STEIN V,; DEUSSING JM,; REFOJO D,

Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition.

NATURE NEUROSCIENCE.; Lugar: Londres; Año: 2015

GIUSTI SA,; VOGL AM,; BROCKMANN M; VERCELLI CA,; REIN T,; TRUMBACH D; WURST W,; CAZALLA D; STEIN V,; DEUSSING JM,; REFOJO D,

MicroRNA-9 controls dendritic development by targeting REST

elife; Año: 2014 vol. 3

LUXENHOFER G, ; HELMBRECHT MS,; LANGHOFF J, ; GIUSTI SA,; REFOJO D,; HUBER AB

MicroRNA-9 promotes the switch from early-born to late-born motor neuron populations by regulating Onecut transcription factor expression.

DEVELOPMENTAL BIOLOGY; Año: 2014 vol. 386 p. 358 - 370

GIUSTI SA,; VERCELLI CA, ; VOGL AM,; KOLARZ A, ; PINO NS, ; DEUSSING JM,; REFOJO D,

Behavioral phenotyping of Nestin-Cre mice: implications for genetic mouse models of psychiatric disorders.

JOURNAL OF PSYCHIATRIC RESEARCH; Lugar: Amsterdam; Año: 2014 vol. 55 p. 87 - 95

BONFIGLIO JJ; INDA C,; SENIN SA,; MACCARRONE G; REFOJO D,; GIACOMINI D,; TURCK CW; HOLSBOER F; ARZT E,; SILBERSTEIN S.

B-Raf and CRHR1 internalization mediate biphasic ERK1/2 activation by CRH in hippocampal HT22 Cells

MOLECULAR ENDOCRINOLOGY; Año: 2013 vol. 27 p. 491 - 510

LIBERMAN AC, ; REFOJO D, ; ANTUNICA-NOGUEROL M, ; HOLSBOER F, ; ARZT E.

Underlying mechanisms of cAMP- and glucocorticoid-mediated inhibition of FasL expression in activation-induced cell death.

MOLECULAR IMMUNOLOGY; Lugar: Amsterdam; Año: 2012 vol. 50 p. 220 - 231

BONFIGLIO JJ,; INDA C,; REFOJO D,; HOLSBOER F; ARZT E,; SILBERSTEIN S.

The corticotropin-releasing hormone network and the hypothalamic-pituitary-adrenal axis: molecular and cellular mechanisms involved.

NEUROENDOCRINOLOGY; Lugar: Basel; Año: 2011 vol. 94 p. 12 - 20

REFOJO D,; SCHWEIZER M, ; KUEHNE C,; EHRENBERG S,; THOERINGER C,; VOGL AM,; DEDIC N, ; SCHUMACHER M, ; VON WOLFF G,; AVRABOS C,; TOUMA C,; ENGBLOM D; SCHÜTZ G; NAVE KA; EDER M,; WOTJAK CT; WURST W,; DEUSSING JM.

Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1.

SCIENCE; Año: 2011 vol. 30 p. 1903 - 1907

SILBERSTEIN S,; VOGL AM, ; BONFIGLIO JJ, ; WURST W, ; HOLSBOER F,; ARZT E,; DEUSSING JM,; REFOJO D,

Immunology, signal transduction, and behavior in hypothalamic-pituitary-adrenal axis-related genetic mouse models

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.; Lugar: Oxford; Año: 2009 p. 120 - 130

SILBERSTEIN S,; VOGL AM,R; REFOJO D,; SENIN SA, ; WURST W, ; HOLSBOER F,; DEUSSING JM,; ARZT E,

Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions

NEUROSCIENCE; Lugar: Amsterdam; Año: 2009 p. 610 - 617

REFOJO D,; HOLSBOER F,

CRH signaling. Molecular specificity for drug targeting in the CNS

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.; Lugar: Oxford; Año: 2009 p. 116 - 119

LIBERMAN AC, ; DRUKER J,; REFOJO D,; HOLSBOER F; ARZT E,

Glucocorticoids inhibit GATA-3 phosphorylation and activity in T cells

FASEB JOURNAL; Lugar: Bethesda; Año: 2009 vol. 23 p. 1558 - 1571

LIBERMAN AC,; DRUKER J,; REFOJO D,; ARZT E,

Molecular mechanisms of action of some immunosuppressive drugs

MEDICINA; Año: 2008 p. 455 - 464

LABEUR M, ; REFOJO D, ; WÖLFEL B, ; STALLA J, ; VARGAS V, ; THEODOROPOULOU M, ; BUCHFELDER M, ; PAEZ-PEREDA M, ; ARZT E, ; STALLA GK.

Interferon-gamma inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway.

JOURNAL OF ENDOCRINOLOGY; Lugar: Bristol; Año: 2008 vol. 199 p. 177 - 189

LU A, ; STEINER MA, ; WHITTLE N, ; VOGL AM, ; WALSER SM, ; ABLEITNER M, ; REFOJO D,; EKKER M, ; RUBENSTEIN JL, `; STALLA GK, ; SINGEWALD N, ; HOLSBOER F, ; WOTJAK CT, ; WURST W, ; DEUSSING JM.

Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior.

MOLECULAR PSYCHIATRY; Lugar: Londres; Año: 2008 vol. 13 p. 1028 - 1042

BRENZ VERCA MS, ; WEBER P, ; MAYER C, ; GRAF C, ; REFOJO D, ; KÜHN R, ; GRUMMT I, ; LUTZ B.

Development of a species-specific RNA polymerase I-based shRNA expression vector

NUCLEIC ACIDS RESEARCH; Lugar: Oxford; Año: 2007 p. 1 - 8

LIBERMAN AC,; REFOJO D,; DRUKER J,; TOSCANO M,; REIN T, ; HOLSBOER F,; ARZT E,

The activated glucocorticoid receptor inhibits the transcription factor T-bet by direct protein-protein interaction

FASEB JOURNAL; Lugar: Bethesda; Año: 2007 p. 1177 - 1188

GIACOMINI D,; PAEZ-PEREDA M,; THEODOROPOULOU M, ; LABEUR M,; REFOJO D,; GEREZ J,; CHERVIN A, ; BERNER S, ; LOSA M, ; BUCHFELDER M,; RENNER U, ; STALLA GK, ; ARZT E,

Bone morphogenetic protein-4 inhibits corticotroph tumor cells: involvement in the retinoic acid inhibitory action

ENDOCRINOLOGY; Año: 2006 p. 247 - 256

GIACOMINI D,; PAEZ-PEREDA M,; THEODOROPOULOU M,; GEREZ J,; NAGASHIMA AC,; CHERVIN A,; BERNER S,; LABEUR M,; REFOJO D,; RENNER U,; STALLA GK,; ARZT E,

Bone morphogenetic protein-4 control of pituitary pathophysiology.

FRONTIERS OF HORMONE RESEARCH.; Lugar: Basel; Año: 2006 p. 22 - 31

DRUKER J,; LIBERMAN AC, ; ACUÑA M, ; GIACOMINI D,; REFOJO D,; SILBERSTEIN S, ; PEREDA MP, ; STALLA GK, ; HOLSBOER F,; ARZT E,

Molecular understanding of cytokine-steroid hormone dialogue: implications for human diseases.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.; Lugar: Oxford; Año: 2006 p. 297 - 306

REFOJO D,; ECHENIQUE C,; MÜLLER MB,; REUL JM,; DEUSSING JM, ; WURST W, ; HOLSBOER F,; ARZT E,

Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2005 p. 6183 - 6188

PAEZ-PEREDA M,; GIACOMINI D,; REFOJO D,; NAGASHIMA AC,; HOPFNER U,; GRUBLER Y,; CHERVIN A, ; GOLDBERG V, ; GOYA R,; HENTGES ST,; LOW MJ, ; HOLSBOER F, ; STALLA GK,; ARZT E,

Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2003 p. 34 - 1039

GIACOMINI D,; PÁEZ-PEREDA M, ; REFOJO D,; CARBIA NAGASHIMA A,; CHERVIN A,; GOLDBERG V,; ARZT E,

New mechanisms involved in the pathogenesis of pituitary adenomas

MEDICINA; Año: 2003 p. 147 - 150

REFOJO D,; LIBERMAN AC,; GIACOMINI D,; CARBIA NAGASHIMA A,; GRACIARENA M,; ECHENIQUE C,; PAEZ-PEREDA M,; STALLA GK,; HOLSBOER F,; ARZT E,

Integrating systemic information at the molecular level: cross-talk between steroid receptors and cytokine signaling on different target cells

Annals of the New York Academy of Sciences; Año: 2003 p. 196 - 204

REFOJO D,; LIBERMAN AC,; ARZT E,

Cytokine signaling/transcription factor cross-talk in T cell activation and Th1-Th2 differentiation

ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS; Lugar: BASEL; Año: 2003 p. 351 - 365

REFOJO D, ; KOVALOVSKY D, ; YOUNG JI, ; RUBINSTEIN M, ; HOLSBOER F, ; REUL JM, ; LOW MJ, ; ARZT E.

Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice.

JOURNAL OF NEUROIMMUNOLOGY; Lugar: Amsterdam; Año: 2002 vol. 131 p. 126 - 134

KOVALOVSKY D, ; REFOJO D, ; LIBERMAN AC, ; HOCHBAUM D, ; PEREDA MP, ; COSO OA, ; STALLA GK, ; HOLSBOER F, ; ARZT E.

Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways.

MOLECULAR ENDOCRINOLOGY; Año: 2002 vol. 16 p. 1638 - 1651

MULLER IGAZ L, ; REFOJO D, ; COSTAS MA, ; HOLSBOER F, ; ARZT E.

CRE-mediated transcriptional activation is involved in cAMP protection of T-cell receptor-induced apoptosis but not in cAMP potentiation of glucocorticoid-mediated programmed cell death.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH; Lugar: Amsterdam; Año: 2002 vol. 30 p. 139 - 148

REFOJO D, ; LIBERMAN AC, ; HOLSBOER F, ; ARZT E.

Transcription factor-mediated molecular mechanisms involved in the functional cross-talk between cytokines and glucocorticoids.

IMMUNOLOGY AND CELL BIOLOGY; Lugar: Londres; Año: 2001 vol. 79 p. 385 - 394

FELEDER C,; ARIAS P,; REFOJO D,; NACHT S,; MOGUILEVSKY JA,

Interleukin-1 inhibits NMDA-stimulated GnRH secretion: associated effects on the release of hypothalamic inhibitory amino acid neurotransmitters.

NEUROIMMUNOMODULATION.; Lugar: Basel; Año: 2000 p. 46 - 50

FELEDER C,; ARIAS P,; REFOJO D,; NACHT S,; MOGUILEVSKY JA,

Age-related differences in the effects of bacterial endotoxin (LPS) upon the release of LHRH, gonadotropins and hypothalamic inhibitory amino acid neurotransmitters measured in tissues explanted from intact male rats.

EXPERIMENTAL CLINICAL ENDOCRINOLOGY & DIABETES; Lugar: ALEMANIA; Año: 2000 p. 220 - 227

KOVALOVSKY D,; REFOJO D,; HOLSBOER F,; ARZT E,

Molecular mechanisms and Th1/Th2 pathways in corticosteroid regulation of cytokine production.

JOURNAL OF NEUROIMMUNOLOGY; Lugar: Amsterdam; Año: 2000 p. 23 - 29

ARZT E, ; KOVALOVSKY D, ; IGAZ LM, ; COSTAS M, ; PLAZAS P, ; REFOJO D, ; PÁEZ-PEREDA M, ; REUL JM, ; STALLA G, ; HOLSBOER F.

Functional cross-talk among cytokines, T-cell receptor, and glucocorticoid receptor transcriptional activity and action.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.; Lugar: Oxford; Año: 2000 vol. 917 p. 672 - 677

RODRÍGUEZ M,; ARIAS P,; REFOJO D,; FELEDER C,; MOGUILEVSKY JA,

Arrest of pulsatile luteinizing hormone (LH) secretion during insulin-induced hypoglycemia (IIH): improvement by intrahypothalamic perfusion with glucose.

EXPERIMENTAL CLINICAL ENDOCRINOLOGY & DIABETES; Lugar: ALEMANIA; Año: 1999 p. 257 - 261

REFOJO D,; ARIAS P,; MOGUILEVSKY JA,; FELEDER C,

Effect of bacterial endotoxin on in vivo pulsatile gonadotropin secretion in adult male rats.

NEUROENDOCRINOLOGY; Lugar: Basel; Año: 1998 p. 275 - 281

FELEDER C,; REFOJO D,; NACHT S,; MOGUILEVSKY JA.

Interleukin-1 stimulates hypothalamic inhibitory amino acid neurotransmitter release.

NEUROIMMUNOMODULATION.; Lugar: Basel; Año: 1998 p. 1 - 4

FELEDER C,; REFOJO D,; JARRY H,; WUTTKE W,; MOGUILEVSKY JA.

Bacterial endotoxin inhibits LHRH secretion following the increased release of hypothalamic GABA levels. Different effects on amino acid neurotransmitter release.

NEUROIMMUNOMODULATION.; Lugar: Basel; Año: 1996 p. 342 - 351

ARIAS P,; FELEDER C, ; RODRÍGUEZ M,; GINZBURG M,; REFOJO D,; SZWARCFARB B,; MOGUILEVSKY JA.

Repeated intracerebroventricular administration of taurine lowers LH levels and postpones vaginal opening in peripubertal female rats.

DEVELOPMENTAL BRAIN RESEARCH; Lugar: Amsterdam; Año: 1995 p. 137 - 139