GABRIEL A. HUNZICKER; MARÍA PÍA RODRIGUEZ; MATIAS N. BALDO; MARÍA CECILIA ACEVEDO; GUILLERMINA LORENZÓN; MARÍA CAROLINA FRITZ; CAROLINA MANSILLA; SOLEDAD VERGARA; LUISINA ROSENBROCK; SEBASTIÁN CEMBAL; SILVINA GOSSIS; MARIO DOMINGUEZ; CARLOS W. BERTONCINI

Estudio de biodisponibilidad comparativa de Binap® (ibrutinib 140 mg) de Laboratorio Varifarma S.A. respecto al producto de referencia Imbruvica®

HEMATOLOGIA; Lugar: Buenos Aires; Año: 2020 vol. 25 p. 25 - 37

TÓTH, GERGELY; NEUMANN, THOMAS; BERTHET, AMANDINE; MASLIAH, ELIEZER; SPENCER, BRIAN; TAO, JIAHUI; JOBLING, MICHAEL F.; GARDAI, SHYRA J.; BERTONCINI, CARLOS W.; CREMADES, NUNILO; BOVA, MICHAEL; BALLARON, STEPHEN; CHEN, XIAO-HUA; MAO, WENXIAN; NGUYEN, PHUONG; TABIOS, MARIANO C.; TAMBE, MITALI A.; ROCHET, JEAN-CHRISTOPHE; JUNKER, HANS-DIETER; SCHWIZER, DANIEL; SEKUL, RENATE; OTT, INGE; ANDERSON, JOHN P.; SZOKE, BALAZS; HOFFMAN, WHERLY; CHRISTODOULOU, JOHN; YEDNOCK, TED; AGARD, DAVID A.; SCHENK, DALE; MCCONLOGUE, LISA

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions

Scientific Reports; Año: 2019 vol. 9

DE MOL, EVA; SZULC, ELZBIETA; DI SANZA, CLAUDIO; MARTÍNEZ-CRISTÓBAL, PAULA; BERTONCINI, CARLOS W.; FENWICK, R. BRYN; FRIGOLÉ-VIVAS, MARTA; MASÍN, MARIANELA; HUNTER, IRENE; BUZÓN, VÍCTOR; BRUN-HEATH, ISABELLE; GARCÍA, JESÚS; DE FABRITIIS, GIANNI; ESTÉBANEZ-PERPIÑÁ, EVA; MCEWAN, IAIN J.; NEBREDA, ÁNGEL R.; SALVATELLA, XAVIER

Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators

STRUCTURE WITH FOLDING & DESIGN.; Año: 2018 vol. 26 p. 145 - 152

DE MOL, EVA; FENWICK, R. BRYN; PHANG, CHRISTOPHER T. W.; BUZÓN, VICTOR; SZULC, ELZBIETA; DE LA FUENTE, ALEX; ESCOBEDO, ALBERT; GARCÍA, JESÚS; BERTONCINI, CARLOS W.; ESTÉBANEZ-PERPIÑÁ, EVA; MCEWAN, IAIN J.; RIERA, ANTONI; SALVATELLA, XAVIER

EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

ACS CHEMICAL BIOLOGY; Lugar: Washington; Año: 2016 vol. 11 p. 2499 - 2505

GERGELY TOTH; SHYRA J. GARDAI; WAGNER ZAGO; CARLOS W. BERTONCINI; NUNILO CREMADES; SUSAN L. ROY; MITALI A. TAMBE; JEAN-CHRISTOPHE ROCHE; CELINE GALVAGNION; GAIA SKIBINSKI; MICHELE VENDRUSCOLO; JOHN CHRISTODOULOU; CHRISTOPHER M. DOBSON; DALE SCHENK; LISA MC. CONLOGUE

Targeting the intrinsically disordered structural ensemble of alpha-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease.

PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 1 - 11

SANTIAGO ESTEBAN-MARTIN; ROBERT BRYN FENWICK; JÖRGEN ÅDÉN; BENJAMIN COSSINS; CARLOS W. BERTONCINI; VICTOR GUALLAR; MAGNUS WOLF-WATZ; XAVIER SALVATELLA

Correlated inter-domain motions in adenylate kinase.

PLOS COMPUTATIONAL BIOLOGY; Lugar: San Francisco; Año: 2014 vol. 10 p. 1 - 7

ELIN K. ESBJORNER; FIONA T.S. CHAN; ERIC REES; MIKLOS ERDELYI; LEILA LUHESHI; CARLOS W. BERTONCINI; CLEMENS F. KAMINSKI; CHRISTOPHER M. DOBSON; GABRIELE S. KAMINSKI SCHIERLE

Direct observations of amyloid beta self-assembly in live cells provide insights into differences in the kinetics of Aβ(1-40) and Aβ(1-42) aggregation

CHEMISTRY & BIOLOGY; Lugar: United States; Año: 2014 vol. 21 p. 732 - 742

MARAL YOLAMANOVA; CHRISTOPH MEIER; ALEXEY K. SHAYTAN; VIRAG VAS; CARLOS W. BERTONCINI; FRANZISKA ARNOLD; ONOFRIO ZIRAFI; SHARIQ M. USMANI; JANIS A. MÜLLER; DANIEL SAUTER; CHRISTINE GOFFINET; DAVID PALESCH; PAUL WALTHER; NADIA R. ROAN; HARTMUT GEIGER; OLEG LUNOV; THOMAS SIMMET; JENS BOHNE; HUBERT SCHREZENMEIER; KLAUS SCHWARZ; LUDGER STÄNDKER; WOLF-GEORG FORSSMANN; XAVIER SALVATELLA; PAVEL G. KHALATUR; ALEXEI R. KHOKHLOV; TUOMAS P. J. KNOWLES; TANJA WEIL; FRANK KIRCHHOFF ; JAN MÜNCH

Peptide nanofibrils boost retroviral gene transfer and provide a rapid means for concentrating viruses.

NATURE NANOTECHNOLOGY; Lugar: Londres; Año: 2013 vol. 8 p. 130 - 136

FIONA T.S. CHAN; GABRIELE S. KAMINSKI SCHIERLE; JANET R. KUMITA; CARLOS W. BERTONCINI; CHRISTOPHER M. DOBSON; CLEMENS F. KAMINSKI

Protein amyloids develop an intrinsic fluorescence signature during aggregation

ANALYST; Lugar: CAMBRIDGE; Año: 2013 vol. 138 p. 2156 - 2162

JORDI SILVESTRE-RYAN; CARLOS W. BERTONCINI; ROBERT BRYN FENWICK; SANTIAGO ESTEBAN-MARTIN; XAVIER SALVATELLA

Average Conformations Determined from PRE Data Provide High-Resolution Maps of Transient Tertiary Interactions in Disordered Proteins

BIOPHYSICAL JOURNAL; Lugar: United States; Año: 2013 vol. 104 p. 1740 - 1751

SANTIAGO ESTEBAN-MARTIN; JORDI SILVESTRE-RYAN; CARLOS W. BERTONCINI; XAVIER SALVATELLA

Identification of fibril-like tertiary contacts in soluble monomeric α-synuclein

BIOPHYSICAL JOURNAL; Lugar: United States; Año: 2013 vol. 105 p. 1192 - 1198

NUNILO CREMADES; SAMUEL I.A. COHEN; EMMA DEAS; ANDREY Y. ABRAMOV; ALLEN Y. CHEN; ANGEL ORTE; MASSIMO SANDAL; RICHARD W. CLARKE; PAUL DUNNE; FRANCESCO A. APRILE; CARLOS W. BERTONCINI; NICHOLAS W. WOOD; TUOMAS P.J. KNOWLES; CHRISTOPHER M. DOBSON; DAVID KLENERMAN

Direct observation of the interconversion of normal and toxic forms of alpha-synuclein

CELL; Lugar: United States; Año: 2012 vol. 149 p. 1048 - 1059

ANDRÉS BINOLFI; LILIANA QUINTANAR; CARLOS W. BERTONCINI; CHRISTIAN GRIESINGER; CLAUDIO O. FERNANDEZ

Bioinorganic chemistry of copper coordination to alpha-synuclein: Relevance to Parkinson's disease

COORDINATION CHEMISTRY REVIEWS; Lugar: Amsterdam; Año: 2012 vol. 256 p. 2188 - 2212

GABRIELE S. KAMINSKI SCHIERLE; CARLOS W. BERTONCINI; FIONA T.S. CHAN; ANNEMIEKE T. VAN DER GOOT; STEPHANIE SCHWEDLER; JEREMY SKEPPER; SIMON SCHLACHTER; TJAKKO J VAN HAM; ALESSANDRO ESPOSITO; JANET R. KUMITA; ELLEN A. NOLLEN; CHRISTOPHER M. DOBSON; CLEMENS F. KAMINSKI; * JOINT FIRST AUTHOR

A FRET sensor for non-invasive imaging of amyloid formation in vivo

Chemphyschem; Lugar: Weinheim; Año: 2011 vol. 12 p. 673 - 680

CARLOS W. BERTONCINI; MARÍA S. CELEJ

Small molecule fluorescent probes for the detection of amyloid self-assembly in vitro and in vivo

CURRENT PROTEIN AND PEPTIDE SCIENCE; Lugar: Oak Park; Año: 2011 vol. 12 p. 206 - 220

SANTIAGO ESTEBAN-MARTIN; CARLOS W. BERTONCINI; XAVIER SALVATELLA

Proteínas escurridizas

INVESTIGACION Y CIENCIA; Lugar: Barcelona; Año: 2011 p. 64 - 65

GABRIELE S. KAMINSKI SCHIERLE; SEBASTIAN VAN DE LINDE; MIKLOS ERDELYI; ELIN K. ESBJORNER; TERESA KLEIN; ERIC REES; CARLOS W. BERTONCINI; CHRISTOPHER M. DOBSON; MARKUS SAUER; CLEMENS F. KAMINSKI

In situ measurements of the formation and morphology of intracellular beta-amyloid fibrils by super-resolution fluorescence imaging

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Lugar: Washington; Año: 2011 vol. 133 p. 12902 - 12905

GONZALO R. LAMBERTO; VALENTINA TORRES-MONTSERRAT; CARLOS W. BERTONCINI; XAVIER SALVATELLA; MARKUS ZWECKSTETTER; CHRISTIAN GRIESINGER; CLAUDIO O. FERNANDEZ

Toward the discovery of effective polycyclic inhibitors of alpha-synuclein amyloid assembly

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2011 vol. 286 p. 32036 - 32044

TJAKKO J VAN HAM; ALESSANDRO ESPOSITO; JANET R. KUMITA; SHANG-TE DANNY HSU; GABRIELE S. KAMINSKI SCHIERLE; CLEMENS F. KAMINSKI; CHRISTOPHER M. DOBSON; ELLEN A. NOLLEN; CARLOS W. BERTONCINI

Towards multiparametric fluorescent imaging of amyloid formation: studies of a YFP model of alpha-synuclein aggregation.

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2010 vol. 395 p. 627 - 642

SOHINI CHAKRABORTEE; FILIP MEERSMAN; GABRIELE S. KAMINSKI SCHIERLE; CARLOS W. BERTONCINI; BRIAN MCGEE; CLEMENS F. KAMINSKI; ALAN TUNNACLIFFE

Catalytic and chaperone-like functions in an intrinsically disordered protein associated with desiccation tolerance.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2010 vol. 107 p. 16084 - 16089

SHANG-TE DANNY HSU; CARLOS W. BERTONCINI; CHRISTOPHER M. DOBSON

Use of protonless NMR spectroscopy to alleviate the loss of information resulting from exchange-broadening.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Lugar: Washington; Año: 2009 vol. 131 p. 7222 - 7223

CHRISTOFER LENDEL; CARLOS W. BERTONCINI; NUNILO CREMADES; CHRISTOPHER A. WAUDBY; MICHELE VENDRUSCOLO; CHRISTOPHER M. DOBSON; DALE SCHENK; JOHN CHRISTODOULOU; GERGELY TOTH; * JOINT FIRST AUTHOR

On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid.

BIOCHEMISTRY; Lugar: Washington; Año: 2009 vol. 48 p. 8322 - 8334

CINTIA ROODVELDT; CARLOS W. BERTONCINI; AUGUST ANDERSSON; ANNEMIEKE T. VAN DER GOOT; SHANG-TE DANNY HSU; RAFAEL FERNÁNDEZ-MONTESINOS; JANNIE DE JONG; TJAKKO J VAN HAM; ELLEN A. NOLLEN; DAVID POZO; JOHN CHRISTODOULOU; CHRISTOPHER M. DOBSON; * JOINT FIRST AUTHOR

Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip.

EMBO JOURNAL; Lugar: Londres; Año: 2009 vol. 28 p. 3758 - 3770

GONZALO R. LAMBERTO; ANDRÉS BINOLFI; MARIA L. ORCELLET; CARLOS W. BERTONCINI; MARKUS ZWECKSTETTER; CHRISTIAN GRIESINGER; CLAUDIO O. FERNANDEZ

Structural and mechanistic basis behind the inhibitory interaction of PcTS on alpha-synuclein amyloid fibril formation.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2009 vol. 106 p. 21057 - 21062

EMIL PALECEK; VERONIKA OSTATNÁ; MICHAL MASARÍK; CARLOS W. BERTONCINI; THOMAS M. JOVIN

Changes in interfacial properties of alpha-synuclein preceding its aggregation

ANALYST; Lugar: CAMBRIDGE; Año: 2008 vol. 133 p. 76 - 84

ANDRÉS BINOLFI; GONZALO R. LAMBERTO; ROSARIO DURAN; LILIANA QUINTANAR; CARLOS W. BERTONCINI; JOSE M. SOUZA; CARLOS CERVEÑANSKY; MARKUS ZWECKSTETTER; CHRISTIAN GRIESINGER; CLAUDIO O. FERNANDEZ

Site-specific interactions of Cu(II) with alpha and beta-synuclein: bridging the molecular gap between metal binding and aggregation.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Lugar: Washington; Año: 2008 vol. 130 p. 11801 - 11812

MARÍA JULIA ROBERTI; CARLOS W. BERTONCINI; REINHARD KLEMENT; ELIZABETH A JARES-ERIJMAN; THOMAS M. JOVIN

Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged alpha-synuclein

NATURE METHODS; Lugar: Londres; Año: 2007 vol. 4 p. 345 - 351

CARLOS W. BERTONCINI; RODOLFO M. RASIA; GONZALO R. LAMBERTO; ANDRÉS BINOLFI; MARKUS ZWECKSTETTER; CHRISTIAN GRIESINGER; CLAUDIO O. FERNANDEZ

Structural characterization of the intrinsically unfolded protein beta-synuclein, a natural negative regulator of alpha-synuclein aggregation.

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2007 vol. 372 p. 708 - 722

ANDRÉS BINOLFI; RODOLFO M. RASIA; CARLOS W. BERTONCINI; MARCELO CEOLÍN; MARKUS ZWECKSTETTER; CHRISTIAN GRIESINGER; THOMAS M. JOVIN; CLAUDIO O. FERNANDEZ

Interaction of alpha-synuclein with divalent metal ions reveals key differences: a link between structure, binding specificity and fibrillation enhancement

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Lugar: Washington; Año: 2006 vol. 128 p. 9893 - 9901

CARLOS W. BERTONCINI; YOUNG-SANG JUNG; CLAUDIO O. FERNANDEZ; WOLFGANG HOYER; CHRISTIAN GRIESINGER; THOMAS M. JOVIN ; MARKUS ZWECKSTETTER

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2005 vol. 102 p. 1430 - 1435

RODOLFO M. RASIA; CARLOS W. BERTONCINI; DEREK MARSH; WOLFGANG HOYER; DMITRY CHERNY; MARKUS ZWECKSTETTER; CHRISTIAN GRIESINGER; THOMAS M. JOVIN; CLAUDIO O. FERNANDEZ

Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2005 vol. 102 p. 4294 - 4299

PAU BERNADÓ; CARLOS W. BERTONCINI; CHRISTIAN GRIESINGER; MARKUS ZWECKSTETTER; MARTIN BLACKLEDGE

Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY; Lugar: Washington; Año: 2005 vol. 127 p. 17968 - 17969

CARLOS W. BERTONCINI; CLAUDIO O. FERNANDEZ; CHRISTIAN GRIESINGER; THOMAS M. JOVIN; MARKUS ZWECKSTETTER

Familial mutants of alpha-synuclein with increased neurotoxicity have a destabilized conformation

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2005 vol. 280 p. 30652 - 30652

CARLOS W. BERTONCINI ; JOSÉ M. RAFFAELLI; LEONARDO FASSINO ; HECTOR S. ODETTI; EDUARDO J. BOTTANI

Phenol adsorption on porous and non-porous carbons

CARBON; Lugar: Amsterdam; Año: 2003 vol. 41 p. 1101 - 1111

ADRIANA E. TRON; CARLOS W. BERTONCINI; RAQUEL L. CHAN; DANIEL H. GONZALEZ

Redox regulation of plant homeodomain transcription factors

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2002 vol. 277 p. 34800 - 34807

CLAUDIA M. PALENA; ADRIANA E. TRON; CARLOS W. BERTONCINI; DANIEL H. GONZALEZ; RAQUEL L. CHAN

Positively charged residues at the N-terminal arm of the homeodomain are required for efficient DNA binding by homeodomain-leucine zipper proteins

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2001 vol. 308 p. 39 - 47

ADRIANA E. TRON; CARLOS W. BERTONCINI; CLAUDIA M. PALENA; RAQUEL L. CHAN; DANIEL H. GONZALEZ

Combinatorial interactions of two amino acids with a single base pair define target site specificity in plant dimeric homeodomain proteins

NUCLEIC ACIDS RESEARCH; Lugar: Oxford; Año: 2001 vol. 29 p. 4866 - 4872

CARLOS W. BERTONCINI; HECTOR S. ODETTI; EDUARDO J. BOTTANI

Computer Simulation of Phenol Physisorption on Graphite

LANGMUIR; Lugar: Washington; Año: 2000 vol. 16 p. 7457 - 7463