INVESTIGADORES
CERIANI Maria Carolina
artículos
GHEZZI, MARCELO DANIEL; CERIANI, MARÍA CAROLINA; DOMÍNGUEZ-OLIVA, ADRIANA; LENDEZ, PAMELA ANAHÍ; OLMOS-HERNÁNDEZ, ADRIANA; CASAS-ALVARADO, ALEJANDRO; HERNÁNDEZ-AVALOS, ISMAEL
Use of Infrared Thermography and Heart Rate Variability to Evaluate Autonomic Activity in Domestic Animals
Animals; Año: 2024 vol. 14
MOTA-ROJAS, DANIEL; GHEZZI, MARCELO DANIEL; HERNANDEZ-AVALOS ISMAEL ; DMINGUEZ-OLIVA ADRIANA; CASAS-ALVARADO ALEJANDRO; LENDEZ, PAMELA A.; CERIANI MARIA CAROLINA; WANG DEHUA
Hypothalamic Neuromodulation of Hypothermia in Domestic Animals
Animals; Año: 2024 vol. 14
SARUBBI JULIANA; MARTINEZ-BURNES JULIO; GHEZZI, MARCELO DANIEL; OLMOS-HERNÁNDEZ, ADRIANA; LENDEZ PAMELA ANAHI; CERIANI MARIA CAROLINA; HERNANDEZ-AVALOS ISMAEL
Hypothalamic Neuromodulation and Control of the Dermal Surface Temperature of Livestock during Hyperthermia
Animals; Lugar: Basel; Año: 2024
DOPAZO JUDIT; AKMENTINS MS; BOULLHESEN M; CERIANI MC; NIETO FARIAS, MARIA VICTORIA; KRUGER ALEJANDRA; BERKUNSKY IGOR
Apparent Batrachochytrium dendrobatidis in the Endangered Gastrotheca chrysosticta (Anura: Hemiphractidae) in Argentina
HERPETOLOGICAL REVIEW; Año: 2023 vol. 54
LADERA GOMEZ MARLA ELIANA; NIETO FARIAS, MARIA VICTORIA; VATER, ADRIAN ALEJANDRO; CERIANI MARIA CAROLINA; DOLCINI GUILLERMINA LAURA
Study of the proviral load levels and mRNA expression of cytokines in peripheral blood mononuclear cells and somatic milk cells in cattle with different BLV infection profiles
VETERINARIA ITALIANA; Lugar: Teramo; Año: 2023 vol. 59 p. 83 - 92
MOTA-ROJAS, DANIEL; BRAGHIERI ADA; GHEZZI, MARCELO DANIEL; CERIANI MARIA CAROLINA; LENDEZ PAMELA ANAHI; SABIA EMILIO; NAPOLITANO FABIO
Strategies and Mechanisms of Thermal Compensation in Newborn Water Buffaloes
Animals; Lugar: Basel; Año: 2023 vol. 13 p. 1 - 31
LENDEZ, PAMELA A.; MARTINEZ CUESTA, L.; NIETO FARIAS, MARIA VICTORIA; VATER, ADRIAN ALEJANDRO; GHEZZI, MARCELO DANIEL; MOTA-ROJAS, DANIEL; DOLCINI, GUILLERMINA LAURA; CERIANI MARIA CAROLINA
Effect of heat stress on TNF-α, TNFRI and TNFRII expression in BLV infected dairy cattle
JOURNAL OF THERMAL BIOLOGY; Lugar: Amsterdam; Año: 2023
LADERA GOMEZ MARLA ELIANA; NIETO FARIAS, MARIA VICTORIA; RODRIGUEZ MARCELO; VATER, ADRIAN ALEJANDRO; CERIANI MARIA CAROLINA; DOLCINI GUILLERMINA LAURA
Altered apoptosis and proliferation in milk cells and PBMc from BLV-infected bovines with different proviral loads: Possible role of the BCL-2 family proteins, TNF-alpha, and receptors
Veterinary Immunology and Immunopathology; Año: 2023 vol. 268
GÓMEZ, MARLA ELIANA LADERA; LENDEZ, PAMELA ANAHÍ; FARIAS, MARÍA VICTORIA NIETO; CERIANI, MARÍA CAROLINA; DOLCINI, GUILLERMINA LAURA
PCR en tiempo real (qPCR): una herramienta útil en el control del virus de la leucosis bovina (BLV) / Real-time PCR (qPCR): a useful tool in the control of bovine leukosis virus (BLV)
Brazilian Journal of Animal and Environmental Research; Año: 2022 vol. 5 p. 963 - 984
SPINA JULIETA; DOLCINI GUILLERMINA LAURA; MORAN PEDRO E; CERIANI MARIA CAROLINA
Relevamiento de la presencia del virus de la Leucosis bovina (BLV) y del Gammaherpesvirusbovino 4 (BoHV-4) en trabajadores rurales de la provincia de Buenos Aires
studies in environmental and animal sciences; Lugar: Curitiba; Año: 2022 vol. 3 p. 1468 - 1478
MUCHIUT, SEBASTIÁN; FIEL, CÉSAR; LIRÓN, JUAN PEDRO; LLOBERAS, MERCEDES; CERIANI, CAROLINA; LORENZO, RAMIRO; RIVA, ELIANA; BERNAT, GISELE; CARDOZO, PATRICIA; FERNÁNDEZ, SILVINA; STEFFAN, PEDRO
Population replacement of benzimidazole-resistant Haemonchus contortus with susceptible strains: evidence of changes in the resistance status
PARASITOLOGY RESEARCH; Año: 2022 vol. 121 p. 2623 - 2632
LENDEZ PAMELA ANAHI; MARTINEZ CUESTA LUCIA; NIETO FARIAS, MARIA VICTORIA; DOLCINI GUILLERMINA LAURA; CERIANI MARIA CAROLINA
Cytokine TNF-α and its receptors TNFRI and TNFRII play a key role in the in vitro proliferative response of BLV infected animals
VETERINARY RESEARCH COMMUNICATIONS; Año: 2021
LENDEZ, PAMELA ANAHÍ; MARTINEZ CUESTA, LUCÍA; NIETO FARIAS, MARIA VICTORIA; VATER, ADRIAN ALEJANDRO; GHEZZI, MARCELO DANIEL; MOTA-ROJAS, DANIEL; DOLCINI, GUILLERMINA LAURA; CERIANI, MARÍA CAROLINA
Alterations in TNF-α and its receptors expression in cows undergoing heat stress
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; Año: 2021 vol. 235 p. 235 - 240
TORRES, CAROLINA; CERIANI, CAROLINA
Cost-Effective Method to Perform SARS-CoV-2 Variant Surveillance: Detection of Alpha, Gamma, Lambda, Delta, Epsilon, and Zeta in Argentina
Frontiers in Medicine; Año: 2021 vol. 8
MARTINEZ CUESTA, L.; LENDEZ, PAMELA A.; SHEAHAN, MAUREEN A.; ROWLAND, RAYMOND R.R.; NIETO FARIAS, MARIA VICTORIA; DOLCINI GUILLERMINA LAURA; CERIANI MARIA CAROLINA
Bovine leukemia virus non-productive infection of human mammary epithelial cells (MCF10A)
Clinical Oncology and Research; Lugar: Tallinn; Año: 2020
LENDEZ PAMELA ANAHI; NIETO FARIAS, MARIA VICTORIA; MARTINEZ CUESTA LUCIA; VATER ADRIAN; MOTA-ROJAS DANIEL; DOLCINI GUILLERMINA LAURA; CERIANI MARIA CAROLINA
Estres por calor: su efecto sobre el estado inmunologico de las vacas lecheras
REVISTA DE MEDICINA VETERINARIA; Lugar: Buenos Aires; Año: 2020 vol. 101 p. 7 - 13
CUESTA, LUCIA MARTINEZ; LIRON, JUAN PEDRO; FARIAS, MARÍA VICTORIA NIETO; DOLCINI, GUILLERMINA LAURA; CERIANI, MARIA CAROLINA
Effect of bovine leukemia virus (BLV) infection on bovine mammary epithelial cells RNA-seq transcriptome profile
PLOS ONE; Año: 2020 vol. 15
MARTINEZ CUESTA, L.; NIETO FARIAS, MARIA VICTORIA; LENDEZ, PAMELA A.; ROWLAND, RAYMOND R.R.; SHEAHAN, MAUREEN A.; CHEUQUEPÁN VALENZUELA, FELIPE A.; MARIN, MAIA S.; DOLCINI, GUILLERMINA; CERIANI, MARIA CAROLINA
Effect of bovine leukemia virus on bovine mammary epithelial cells
VIRUS RESEARCH; Año: 2019 vol. 271 p. 67 - 75
BURUCÚA, M.M.; QUINTANA, S.; LENDEZ, P.; COBO, E.R.; CERIANI, M.C.; DOLCINI, G.; ODEÓN, A.C.; PÉREZ, S.E.; MARIN, M.S.
Modulation of cathelicidins, IFNβ and TNFα by bovine alpha-herpesviruses is dependent on the stage of the infectious cycle
MOLECULAR IMMUNOLOGY; Año: 2019 vol. 111 p. 136 - 144
MARTINEZ CUESTA, LUCIA; NIETO FARIAS, MARIA VICTORIA; LENDEZ, PAMELA ANAHI; BARONE, LUCAS; PÉREZ, SANDRA ELIZABETH; DOLCINI, GUILLERMINA LAURA; CERIANI, MARIA CAROLINA
Stable infection of a bovine mammary epithelial cell line (MAC-T) with bovine leukemia virus (BLV)
VIRUS RESEARCH; Año: 2018 vol. 256 p. 11 - 16
LENDEZ PAMELA ANAHI; MARTINEZ CUESTA LUCIA; NIETO FARIAS, MARIA VICTORIA; SHEN HUA MIN; DOLCINI, GUILLERMINA LAURA; BUEHRING GERTRUDE; CERIANI MARIA CAROLINA
Bovine Leukemia Virus Presence in Breast Tissue of Argentinian Females and Its Association With Cell Proliferation and Prognosis Markers
Multidisciplinary Cancer Investigation; Lugar: Teheran; Año: 2018 vol. 2 p. 16 - 24
MARTINEZ CUESTA, LUCIA; LENDEZ, PAMELA ANAHI; NIETO FARIAS, MARIA VICTORIA; DOLCINI, GUILLERMINA LAURA; CERIANI, MARIA CAROLINA
Can Bovine Leukemia Virus Be Related to Human Breast Cancer? A Review of the Evidence
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA; Año: 2018
NIETO FARIAS, MARIA VICTORIA; NOGUEIRA SOUZA FERNANDO; LENDEZ, PAMELA ANAHI; MARTINEZ CUESTA, LUCIA; REIS SANTOS KAMILA; DELLA LIBERA ALICE MELVILLE PAIVA; CERIANI MARIA CAROLINA; DOLCINI, GUILLERMINA LAURA
Lymphocyte proliferation and apoptosis of lymphocyte subpopulations in bovine leukemia virus-infected dairy cows with high and low proviral loa
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; Lugar: Amsterdam; Año: 2018 vol. 206 p. 41 - 48
GENTILE JORGE; HERNANDEZ CLAUDIA; SPARO MONICA; RODRIGUEZ EDGARDO; CERIANI CAROLINA; BRUGGESSER FLORENCIA
Bacteremic Pneumococcal Pneumonia: a Longitudinal Study in 279 Adult Patients from a Single Center
Jourmal of Respiratory Infections; Lugar: Louisville; Año: 2018 vol. 2 p. 47 - 51
BENAVIDES BIBIANA; MUÑOZ SEBASTIAN; CERIANI CAROLINA
Molecular analysis of dairy cows from Pasto, Nariño fragment of bovine leukemia virus env gen by nested-PCR in dai
Revista de Medicina Veterinaria; Lugar: Bogota; Año: 2017 vol. 33 p. 67 - 75
NIETO FARIAS VICTORIA; CAFFARO MARIA EUGENIA; LENDEZ PAMELA ANAHI; PASSUCCI JUAN ANTONIO; POLI MARIO ANDRES; CERIANI MARIA CAROLINA; DOLCINI GUILLERMINA LAURA
A novel association of BoLA DRB3 alleles in BLV infected cattle with different proviral loads.
BRAZILIAN JOURNAL OF VETERINARY RESEARCH AND ANIMAL SCIENCE; Lugar: San Pablo; Año: 2017 vol. 54 p. 215 - 224
LENDEZ PAMELA ANAHI; NIETO FARIAS VICTORIA; DOLCINI GUILLERMINA LAURA; CERIANI MARIA CAROLINA
EXPRESIÓN DEL DOMINIO EXTRACELULAR DEL RECEPTOR DE TIPO II DEL FACTOR DE NECROSIS TUMORAL (TNF-a) Y SU INFLUENCIA EN LA PROLIFERACIÓN DE LINFOCITOS BOVINOS INFECTADOS CON BLV
REVISTA DE MEDICINA VETERINARIA; Lugar: Buenos Aires; Año: 2016 vol. 97 p. 41 - 41
JULIARENA MARCELA; BARRIOS CLARISA; CERIANI CAROLINA; ESTEBAN EN
Bovine leukemia virus infected cows with low proviral load are not a source of infection for BLV-free cattle
JOURNAL OF DAIRY SCIENCE; Lugar: Champaign, Illinois; Año: 2016 vol. 99 p. 4586 - 4589
NIETO FARIAS VICTORIA; LENDEZ PAMELA ANAHI; MARTINEZ CUESTA LUCIA; CERIANI MARIA CAROLINA; DOLCINI GUILLERMINA LAURA
ESTUDIOS DE RESPUESTA PROLIFERATIVA ESTRES OXIDATIVO EN ANIMALES INFECTADOS CON EL VIRUS DE LA LEUCOSIS BOVINA (BLV) CON ALTA Y BAJA CARGA PROVIRAL.
REVISTA DE MEDICINA VETERINARIA; Lugar: Buenos Aires; Año: 2016 vol. 97 p. 71 - 71
NIETO FARIAS VICTORIA; LENDEZ PAMELA ANAHI; MARIN MAIA; QUINTANA SILVINA; MARTINEZ CUESTA LUCIA; CERIANI MARIA CAROLINA; DOLCINI GUILLERMINA
Toll-like receptors, IFN-γ and IL-12 expression in bovine leukemia virus-infected animals with low or high proviral load
RESEARCH IN VETERINARY SCIENCE; Lugar: Amsterdam; Año: 2016
LENDEZ PAMELA ANAHI; PASSUCCI JUAN ANTONIO; POLI MARIO; GUTIERREZ SE; DOLCINI GUILLERMINA; CERIANI MARIA CAROLINA
Association of TNF-α gene promoter region polymorphisms in bovine leukemia virus (BLV) infected cattle with different proviral loads
ARCHIVES OF VIROLOGY; Lugar: Viena; Año: 2015 vol. 160 p. 2001 - 2007
JULIARENA M; LENDEZ PAMELA ANAHI; GUTIERREZ SE; FORLETTI AGUSTINA; RENSETTI DE; CERIANI MARIA CAROLINA
Partial molecular characterization of different proviral strains of bovine leukemia virus
ARCHIVES OF VIROLOGY; Lugar: Viena; Año: 2013 vol. 158 p. 63 - 70
FORLETTI AGUSTINA; JULIARENA M; CERIANI MARIA CAROLINA; AMADIO ARIEL; ESTEBAN EN; GUTIERRES SE
Identification of cattle carrying alleles associated with resistance and susceptibility to the Bovine Leukemia Virus progression by real-time PCR
RESEARCH IN VETERINARY SCIENCE; Lugar: Amsterdam; Año: 2013 vol. 34 p. 243 - 249
CONTI JP; CERIANI MC; JULIARENA M; ESTEBAN EN
Perfil proteico y peptídico de una base fluida para bebidas funcionales obtenida por fermentación del lactosuero
REVISTA INFORMACION TECNOLOGICA DEL CHILE; Lugar: La Serena; Año: 2012 vol. 23 p. 61 - 70
PEREZ SANDRA E; VERNA ANDREA E; LEUNDA MARIA ROSA; FAVIER PAULA ARIELA; CERIANI MARIA CAROLINA; MORAN PEDRO E; ODEON ANSELMO; ESTEBAN EDUARDO
Occurrence of bovine herpesvirus type 4 DNA in Argentinean Holstein cattle from Santiago del Estero, Argentina
BRAZILIAN JOURNAL OF VETERINARY RESEARCH AND ANIMAL SCIENCE; Lugar: San Pablo; Año: 2011 vol. 48 p. 454 - 463
LENDEZ PAMELA ANAHI; JULIARENA M; GUTIERREZ SE; DOLCINI GUILLERMINA; CERIANI MARIA CAROLINA
Polimorfismo del promotor del gen TNF-alfa; (p-TNF-alfa) bovino y su asociación con la resistencia del huesped a la diseminación del virus de la leucosis
REDVET; Lugar: Malaga; Año: 2010 vol. 11 p. 1 - 10
JULIARENA MARCELA; POLI MARIO; CERIANI CAROLINA; SALA LIVIO; RODRIGUEZ EDGARDO; GUTIERREZ SILVINA; DOLCINI GUILLERMINA; ODEON ANSELMO; ESTEBAN EDUARDO
Antibody Response against Three Widespread Bovine Viruses is not Impaired in Holstein Cattle Bovine Leukocyte Antigen (BoLA) DRB3.2 Carrying Alleles Associated with Bovine Leukemia Virus Resistance.
JOURNAL OF DAIRY SCIENCE; Año: 2009 vol. 92 p. 375 - 381
SOLANA HD; SCARCELLA SILVANA; VIRKEL G; CERIANI MC; RODRIGUEZ JA; LANUSSE CE
Albendazole enantiomeric metabolism and binding to cytosolic proteins in the liver fluke fasciola hepatica
VETERINARY RESEARCH COMMUNICATIONS; Año: 2009 vol. 33 p. 163 - 173
DUBE SYAMALIMA; ABBOT LYNN; DUBE DIPAK; DOLCINI GUILLERMINA; GUTIERREZ SILVINA; CERIANI CAROLINA; JULIARENA MARCELA; FERRER JORGE; PERZOVA RAISA; POIESZ BERNARD
The complete genomic sequence of an in vivo low replicating BLV strain
VIROLOGY JOURNAL; Año: 2009 vol. 3 p. 120 - 129
GUTIERREZ SE; CERIANI MC; JULIARENA M; FERRER JF
Host soluble factors that regulate the synthesis of the major core protein of the Bovine Leukemia Virus (BLV) in a naturally-infected neoplastic B-cell line
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY; Año: 2009 vol. 131 p. 246 - 258
JULIARENA MARCELA; POLI MARIO; SALA LIVIO; CERIANI CAROLINA; GUTIERREZ SILVINA; DOLCINI GUILLERMINA; RODRIGUEZ EDGARDO; MARIÑO BETINA; RODRIGUEZ DUBRA CAIN; ESTEBAN EDUARDO
Association of BLV-infection profiles with alleles of BoLA DRB3.2 gene
ANIMAL GENETICS; Año: 2008 vol. 39 p. 432 - 438
SOLANA H., CERIANI C. SCARCELLA S., LANUSSE C.
Molecular characterization of Fasciola hepatica triclabendazole-susceptible and resistant by RAPD-PCR method
BIOCELL; Año: 2007 p. 109 - 109
SCARCELLA SILVANA; CERIANI CAROLINA; RODRIGUEZ JULIO; SOLANA HUGO
Caracterizacion de la proteina microtubular de diferentes helmintos parasitos. Sus implicancias en el modo de accion de los benzimidazoles antihelminticos.
REDVET; Año: 2007 vol. VIII p. 1 - 8
JULIARENA MARCELA, GUTIERREZ SILVINA , CERIANI CAROLINA
Determination of proviral load in bovine leukemia virus-infected cattle with and without lymphocytosis
AMERICAN JOURNAL OF VETERINARY RESEARCH; Año: 2007 vol. 68 p. 1220 - 1225
JULIARENA MARCELA, GUTIERREZ SILVINA , CERIANI CAROLINA
Chicken antibodies: a useful tool for antigen capture ELISA to detect bovine leukemia virus without cross-reaction with other mammalian antibodies.
VETERINARY RESEARCH COMMUNICATIONS; Lugar: Heidelberg; Año: 2006 vol. 31 p. 43 - 51
SPARO M, CASTRO M, ANDINO P, LAVIGNE M, CERIANI C, GUTIERREZ G, FERNANDEZ M, DE MARZI M, MALCHIODI E, MANGHI MA.
Partial characterization of enterocin MR99 from a corn silage isolate of Enterococcus faecalis
JOURNAL OF APPLIED MICROBIOLOGY; Lugar: Belfast, UK; Año: 2006 vol. 100 p. 123 - 134
SOLNA H, VIRKEL G, RODRIGUEZ J,CERIANI C, MOTTIER L, ALVAREZ L, LANUSSE C.
Enhanced albendazole sulphoxidative metabolism in triclabendazole-resistant liver flukes
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS; Año: 2006 vol. 29 p. 123 - 123
SOLANA HD., CERIANI C., RODRIGUEZ J., FAIRWEATHER I., LANUSSE C.
Variacion del patrón electroforético de proteínas microsomales de Fasciola hepática resistente a triclabendazole?.
Parasitologia Latinoamericana; Año: 2005 p. 299 - 300
JULIARENA M, CERIANI C, SALA L, POLI M , DOLCINI G, GUTIERREZ S*, DUBE S, POIESZ B, FERRER J.
Posible papel de los alelos del gen BoLA DRB3.2* en el control del virus de la leucosis bovina (BLV
Revista Argentina de Produccion animal; Lugar: Balcarce; Año: 2004 p. 0 - 0
DUBE S., DOLCINI G., ABBOT L., MEHTA S., DUBE D., GUTIERREZ S., CERIANI C., ESTEBAN E., FERRER J., POIESZ B. VIROLOGY
The complete genomic sequence of a BLV strain from a Holstein cow from Argentina.
VIROLOGY; Lugar: New York; Año: 2000 p. 369 - 376
CAROLINA CARRILLO, SILVINA CEJAS,MICAELA CORTES, CAROLINA CERIANI, ALEJANDRA HUBER, NELIDA S.GONZALEZ AND ISRAEL D.ALGRANATI
Sensitivity of Trypanosomatid Protozoa to DFMO and Metabolic Turnover of Ornithine Decarboxylase.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2000 p. 673 - 679
CAROLINA CERIANI, CAROLINA CARRILLO, NELIDA GONZALEZ E ISRAEL ALGRANATI.
Estabilidad metabolica de la ornitina decarboxilasa y sensibilidad a la droga ?-difluorometilornitna de parasitos tripanosomatidos
Anales de la Asociación Química Argentina; Lugar: Buenos Aires; Año: 1998 p. 221 - 228
SVENSSON FREDRIK; CERIANI CAROLINA; LOVKVIST EVA; KOCKUM INGER; ALGRANATI ISRAEL D; HEBY OLLE; PERSSON LO
Cloning of a trypanosomatid gene coding for an ornithine decarboxylase that is metabolically unstable even though it lacks the C-terminal degradation domain.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 1997 vol. 94 p. 397 - 402
CERIANI CAROLINA; CANOSA LUIS F; FRIDMAN OSVALDO
Serum sex-steroid binding protein in the fresh water teleost "Anguila criolla", Symbranchus marmoratus (Symbranchyformes)
Revista de Ictiologia; Año: 1994 vol. 2/3 p. 21 - 26
GONZALEZ NÉLIDA, CERIANI CAROLINA , ALGRANATI ISRAEL
Transporte de poliaminas en Tripanosomátidos
Anales de la Asociación Química Argentina; Lugar: Buenos Aires; Año: 1993 p. 117 - 125
CERIANI CAROLINA; GONZALEZ NELIDA SUSANA; ALGRANATI ISRAEL D
Ornithine decarboxilase from Crithidia fasciculata is metabolically unstable and resistant to polyamine down-regulation
FEBS LETTERS; Año: 1992 vol. 301 p. 261 - 264
GONZALEZ NELIDA SUSANA; CERIANI CAROLINA; ALGRANATI ISRAEL D
Differential regulation of putrescine uptake in Trypanosoma cruzi and other trypanosomatids
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 1992 vol. 188 p. 120 - 128