PEÑA AGUDELO, JORGE A.; PIDRE, MATÍAS L.; GARCIA FALLIT, MATIAS; PÉREZ KÜPER, MELANIE; ZUCCATO, CAMILA; NICOLA CANDIA, ALEJANDRO J.; MARCHESINI, ABRIL; VERA, MARIANA B.; DE SIMONE, EMILIO; GIAMPAOLI, CARLA; AMORÓS MORALES, LESLIE C.; GONZALEZ, NAZARENO; ROMANOWSKI, VÍCTOR; VIDELA-RICHARDSON, GUILLERMO A.; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Mitochondrial Peptide Humanin Facilitates Chemoresistance in Glioblastoma Cells

Cancers; Año: 2023 vol. 15

GARCÍA FALLIT, MATÍAS; PIDRE, MATÍAS L.; ANTONELA ASAD; PEÑA AGUDELO, JORGE A.; VERA, MB; NICOLA CANDIA, ALEJANDRO J; SAGRIPANTI, SB; PEREZ KUPER, M; AMOROS MORALES, LC; MARCHESINI, A; GONZALEZ, NAZARENO; CARUSO, CARLA; ROMANOWSKI, VÍCTOR; SEILICOVICH, ADRIANA; VIDELA-RICHARDSON, GA; FLAVIA ZANETTI; CANDOLFI, MARIANELA

Evaluation of baculoviruses as gene therapy vectors for brain cáncer

VIRUSES; Año: 2023

ZÁRATE, LORENA V.; MIRET, NOELIA V.; NICOLA CANDIA, ALEJANDRO J.; ZAPPIA, C. DANIEL; PONTILLO, CAROLINA A.; CHIAPPINI, FLORENCIA A.; MONCZOR, FEDERICO; CANDOLFI, MARIANELA; RANDI, ANDREA S.

Breast cancer progression and kynurenine pathway enzymes are induced by hexachlorobenzene exposure in a Her2-positive model

FOOD AND CHEMICAL TOXICOLOGY; Año: 2023 vol. 177

NICOLA CANDIA, ALEJANDRO J.; GARCIA FALLIT, MATÍAS; PEÑA AGUDELO, JORGE A.; PÉREZ KÜPER, MELANIE; GONZALEZ, NAZARENO; MORENO AYALA, MARIELA A.; DE SIMONE, EMILIO; GIAMPAOLI, CARLA; CASARES, NOELIA; SEILICOVICH, ADRIANA; LASARTE, JUAN JOSÉ; ZANETTI, FLAVIA A.; CANDOLFI, MARIANELA

Targeting FOXP3 Tumor-Intrinsic Effects Using Adenoviral Vectors in Experimental Breast Cancer

Viruses; Año: 2023 vol. 15

AMORÓS MORALES, LESLIE C.; MARCHESINI, ABRIL; GÓMEZ BERGNA, SANTIAGO M.; GARCÍA FALLIT, MATÍAS; TONGIANI, SILVANA E.; VÁSQUEZ, LARISA; FERRELLI, MARÍA LETICIA; VIDELA-RICHARDSON, GUILLERMO A.; CANDOLFI, MARIANELA; ROMANOWSKI, VÍCTOR; PIDRE, MATÍAS L.

PluriBAC: A Versatile Baculovirus-Based Modular System to Express Heterologous Genes in Different Biotechnological Platforms

Viruses; Año: 2023 vol. 15

ALGHAMRI, MAHMOUD S.; BANERJEE, KAUSHIK; MUJEEB, ANZAR A.; MAUSER, AVA; TAHER, AYMAN; THALLA, ROHIT; MCCLELLAN, BRANDON L.; VARELA, MARIA L.; STAMATOVIC, SVETLANA M.; MARTINEZ-REVOLLAR, GABRIELA; ANDJELKOVIC, ANUSKA V.; GREGORY, JASON V.; KADIYALA, PADMA; CALINESCU, ALEXANDRA; JIMÉNEZ, JENNIFER A.; APFELBAUM, APRIL A.; LAWLOR, ELIZABETH R.; CARNEY, STEPHEN; COMBA, ANDREA; FAISAL, SYED MOHD; BARISSI, MARCUS; EDWARDS, MARTA B.; APPELMAN, HENRY; SUN, YILUN; GAN, JINGYAO; ACKERMANN, ROSE; SCHWENDEMAN, ANNA; CANDOLFI, MARIANELA; OLIN, MICHAEL R.; LAHANN, JOERG; LOWENSTEIN, PEDRO R.; CASTRO, MARIA G.

Systemic Delivery of an Adjuvant CXCR4-CXCL12 Signaling Inhibitor Encapsulated in Synthetic Protein Nanoparticles for Glioma Immunotherapy

ACS NANO; Año: 2022 vol. 16 p. 8729 - 8750

ASAD, ANTONELA SOFÍA; CANDIA, ALEJANDRO JAVIER NICOLA; GONZÁLEZ, NAZARENO; ZUCCATO, CAMILA FLORENCIA; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Current Non-Viral Gene Therapy Strategies for the Treatment of Glioblastoma

CURRENT MEDICINAL CHEMISTRY.; Año: 2021 vol. 28

GARCIA-FABIANI, MARIA B.; HAASE, SANTIAGO; COMBA, ANDREA; CARNEY, STEPHEN; MCCLELLAN, BRANDON; BANERJEE, KAUSHIK; ALGHAMRI, MAHMOUD S.; SYED, FAISAL; KADIYALA, PADMA; NUNEZ, FELIPE J.; CANDOLFI, MARIANELA; ASAD, ANTONELA; GONZALEZ, NAZARENO; AIKINS, MARISA E.; SCHWENDEMAN, ANNA; MOON, JAMES J.; LOWENSTEIN, PEDRO R.; CASTRO, MARIA G.

Genetic Alterations in Gliomas Remodel the Tumor Immune Microenvironment and Impact Immune-Mediated Therapies

Frontiers in Oncology; Año: 2021 vol. 11

BANERJEE, KAUSHIK; NÚÑEZ, FELIPE J.; HAASE, SANTIAGO; MCCLELLAN, BRANDON L.; FAISAL, SYED M.; CARNEY, STEPHEN V.; YU, JIN; ALGHAMRI, MAHMOUD S.; ASAD, ANTONELA S.; CANDIA, ALEJANDRO J. NICOLA; VARELA, MARIA LUISA; CANDOLFI, MARIANELA; LOWENSTEIN, PEDRO R.; CASTRO, MARIA G.

Current Approaches for Glioma Gene Therapy and Virotherapy

Frontiers in Molecular Neuroscience; Año: 2021 vol. 14

GONZALEZ, NAZARENO; ASAD, ANTONELA S.; GÓMEZ ESCALANTE, JOSÉ; PEÑA AGUDELO, JORGE A.; NICOLA CANDIA, ALEJANDRO J.; GARCÍA FALLIT, MATÍAS; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Potential of IDH mutations as immunotherapeutic targets in gliomas: a review and meta-analysis

EXPERT OPINION ON THERAPEUTIC TARGETS; Año: 2021 vol. 25 p. 1045 - 1060

ASAD, ANTONELA S; NICOLA CANDIA, ALEJANDRO J; GONZALEZ, NAZARENO; ZUCCATO, CAMILA F; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

The role of the prolactin receptor pathway in the pathogenesis of glioblastoma: what do we know so far?

EXPERT OPINION ON THERAPEUTIC TARGETS; Año: 2020 vol. 11 p. 1221 - 1233

MORENO AYALA, MARIELA A.; GOTTARDO, MARÍA FLORENCIA; ZUCCATO, CAMILA FLORENCIA; PIDRE, MATÍAS LUIS; NICOLA CANDIA, ALEJANDRO JAVIER; ASAD, ANTONELA SOFIA; IMSEN, MERCEDES; ROMANOWSKI, VÍCTOR; CRETON, ALDO; ISLA LARRAIN, MARINA; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Humanin Promotes Tumor Progression in Experimental Triple Negative Breast Cancer

Scientific Reports; Año: 2020 vol. 10

ALTSHULER, DAVID B.; KADIYALA, PADMA; NUÑEZ, FELIPE J.; NUÑEZ, FERNANDO M.; CARNEY, STEPHEN; ALGHAMRI, MAHMOUD S.; GARCIA-FABIANI, MARIA B.; ASAD, ANTONELA S.; NICOLA CANDIA, ALEJANDRO J.; CANDOLFI, MARIANELA; LAHANN, JOERG; MOON, JAMES J.; SCHWENDEMAN, ANNA; LOWENSTEIN, PEDRO R.; CASTRO, MARIA G.

Prospects of biological and synthetic pharmacotherapies for glioblastoma

EXPERT OPINION ON BIOLOGICAL THERAPY; Año: 2020 vol. 20 p. 305 - 317

GARCIA-FABIANI, MARIA B.; VENTOSA, MARIA; COMBA, ANDREA; CANDOLFI, MARIANELA; NICOLA CANDIA, ALEJANDRO J.; ALGHAMRI, MAHMOUD; KADIYALA, PADMA; CARNEY, STEPHEN; FAISAL, SYED M.; SCHWENDEMAN, ANNA; MOON, JAMES J.; SCHEETZ, LINDSAY; LAHANN, JOERG; MAUSER, AVA; LOWENSTEIN, PEDRO R.; CASTRO, MARIA G.

Immunotherapy for gliomas: shedding light on progress in preclinical and clinical development

EXPERT OPINION ON INVESTIGATIONAL DRUGS; Año: 2020

GORI, SOLEDAD; ALCAIN, JULIETA; VANZULLI, SILVIA; MORENO AYALA, MARIELA A.; CANDOLFI, MARIANELA; JANCIC, CAROLINA; GEFFNER, JORGE; VERMEULEN, MÓNICA; SALAMONE, GABRIELA

Acetylcholine-treated murine dendritic cells promote inflammatory lung injury

PLOS ONE; Año: 2019 vol. 14

ZUCCATO, CAMILA FLORENCIA; ASAD, ANTONELA SOFIA; NICOLA CANDIA, ALEJANDRO JAVIER; GOTTARDO, MARÍA FLORENCIA; MORENO AYALA, MARIELA ALEJANDRA; THEAS, MARÍA SUSANA; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseases

EXPERT OPINION ON THERAPEUTIC TARGETS; Año: 2019 vol. 23 p. 117 - 126

DE DIOS, NATALY; ORRILLO, SANTIAGO; IRIZARRI, MARTÍN; THEAS, MARÍA SUSANA; BOUTILLON, FLORENCE; CANDOLFI, MARIANELA; SEILICOVICH, ADRIANA; GOFFIN, VINCENT; PISERA, DANIEL; FERRARIS, JIMENA

JAK2/STAT5 pathway mediates prolactin-induced apoptosis of lactotropes

NEUROENDOCRINOLOGY; Año: 2019 vol. 108 p. 84 - 97

ANTONELA ASAD; ALEJANDO JAVIER NICOLA CANDIA; NAZARENO GONZALEZ; CAMILA ZUCCATO; ARACELLI ABT; SANTIAGO JORDI ORRILLO; YAEL LASTRA; EMILIO DE SIMONE; FLORENCE BOUTILLON; VINCENT GOFFIN; ADRIANA SEILICOVICH; DANIEL PISERA; JIMENA FERRARIS; MARIANELA CANDOLFI

Prolactin and its receptor as therapeutic targets in glioblastoma multiforme

Scientific Reports; Año: 2019

KAMRAN, NEHA; ALGHAMRI, MAHMOUD S.; NUNEZ, FELIPE J.; SHAH, DIANA; ASAD, ANTONELA S.; CANDOLFI, MARIANELA; ALTSHULER, DAVID; LOWENSTEIN, PEDRO R.; CASTRO, MARIA G.

Current state and future prospects of immunotherapy for glioma

IMMUNOTHERAPY; Año: 2018 vol. 10 p. 317 - 339

GOTTARDO, MARÍA FLORENCIA; PIDRE, MATÍAS L.; ZUCCATO, CAMILA; ASAD, ANTONELA S.; IMSEN, MERCEDES; JAITA, GABRIELA; CANDOLFI, MARIANELA; ROMANOWSKI, VÍCTOR; SEILICOVICH, ADRIANA

Baculovirus-based gene silencing of Humanin for the treatment of pituitary tumors

APOPTOSIS; Año: 2018 vol. 23 p. 143 - 151

M CHANDRAN; MARIANELA CANDOLFI; D SHAH; YOHEI MINEHARU; VN YADAV; CARL KOSCHMANN; ANTONELA ASAD; PEDRO R LOWENSTEIN; MARIA G CASTRO

Single vs. combination immunotherapeutic strategies for glioma

EXPERT OPINION ON BIOLOGICAL THERAPY; Lugar: London; Año: 2017

NEHA KAMRAN; P KADIVALA; VANDANA SAXENA; MARIANELA CANDOLFI; Y LI; MARIELA MORENO AYALA; N RAJA; D SHAH; PEDRO R LOWENSTEIN; MARIA G CASTRO

Immunosuppressive Myeloid Cells' Blockade in the Glioma Microenvironment Enhances the Efficacy of Immune-Stimulatory Gene Therapy

MOLECULAR THERAPY (PRINT); Lugar: Londres; Año: 2017

MARIELA MORENO AYALA; MARIA FLORENCIA GOTTARDO; ANTONELA ASAD; CAMILA ZUCCATO; ALEJANDO JAVIER NICOLA CANDIA; ADRIANA SEILICOVICH; MARIANELA CANDOLFI

Immunotherapy for the treatment of breast cancer.

EXPERT OPINION ON BIOLOGICAL THERAPY; Lugar: London; Año: 2017

ANTONELA ASAD; MARIELA MORENO AYALA; MARIA FLORENCIA GOTTARDO; CAMILA ZUCCATO; ALEJANDO JAVIER NICOLA CANDIA; FLAVIA ZANETTI; ADRIANA SEILICOVICH; MARIANELA CANDOLFI

Viral gene therapy for breast cancer: progress and challenges

EXPERT OPINION ON BIOLOGICAL THERAPY; Lugar: London; Año: 2017

MORENO AYALA, MARIELA A.; GOTTARDO, MARÍA FLORENCIA; GORI, MARÍA SOLEDAD; NICOLA CANDIA, ALEJANDRO JAVIER; CARUSO, CARLA; DE LAURENTIIS, ANDREA; IMSEN, MERCEDES; KLEIN, SLOBODANKA; BAL DE KIER JOFFÉ, ELISA; SALAMONE, GABRIELA; CASTRO, MARIA G.; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Dual activation of Toll-like receptors 7 and 9 impairs the efficacy of antitumor vaccines in murine models of metastatic breast cancer

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY; Año: 2017 p. 1 - 20

GOTTARDO, MARÍA FLORENCIA; MORENO AYALA, MARIELA; FERRARIS, JIMENA; ZÁRATE, SANDRA; PISERA, DANIEL; CANDOLFI, MARIANELA; JAITA, GABRIELA; SEILICOVICH, ADRIANA

Humanin inhibits apoptosis in pituitary tumor cells through several signaling pathways including NF-κB activation

Journal of Cell Communication and Signaling; Año: 2017 p. 1 - 12

MORENO AYALA, MARIELA A.; GOTTARDO, MARÍA FLORENCIA; IMSEN, MERCEDES; ASAD, ANTONELA SOFIA; BAL DE KIER JOFFÉ, ELISA; NOELIA CASARES; JUAN JOSE LASARTE; SEILICOVICH, ADRIANA; CANDOLFI, MARIANELA

Therapeutic blockade of Foxp3 in experimental breast cancer models

BREAST CANCER RESEARCH AND TREATMENT; Lugar: Berlin; Año: 2017 p. 393 - 405

MARIA LAURA MAGRI; MARIA FLORENCIA GOTTARDO; SANDRA ZARATE; GUADALUPE EIJO; JIMENA FERRARIS; GABRIELA JAITA; MARIELA MORENO AYALA; MARIANELA CANDOLFI; DANIEL PISERA; ADRIANA SEILICOVICH

Opposite effects of dihydrotestosterone and estradiol on apoptosis in the anterior pituitary gland from male rats

ENDOCRINE; Lugar: Oregon; Año: 2016 vol. 51 p. 506 - 516

NEHA KAMRAN; ALEXANDRA CALINESCU; MARIANELA CANDOLFI; M CHANDRAN; YOHEI MINEHARU; ANTONELA ASAD; CARL KOSCHMANN; F NUNEZ; PEDRO R LOWENSTEIN; MARIA G CASTRO

Recent advances and future of immunotherapy for glioblastoma

EXPERT OPINION ON BIOLOGICAL THERAPY; Lugar: London; Año: 2016

GUADALUPE EIJO; MARIA FLORENCIA GOTTARDO; GABRIELA JAITA; MARIA LAURA MAGRI; MARIELA MORENO AYALA; SANDRA ZARATE; MARIANELA CANDOLFI; DANIEL PISERA; ADRIANA SEILICOVICH

Lack of oestrogenic inhibition of the NF-kB Pathway in somatolactotroph tumour cells.

JOURNAL OF NEUROENDOCRINOLOGY.; Lugar: Londres; Año: 2015

MARIA FLORENCIA GOTTARDO; GABRIELA JAITA; MARIA LAURA MAGRI; SANDRA ZARATE; MARIELA MORENO AYALA; JIMENA FERRARIS; GUADALUPE EIJO; DANIEL PISERA; MARIANELA CANDOLFI; ADRIANA SEILICOVICH

Antiapoptotic factor Humanin is expressed in normal and tumoral pituitary cells and protects them from TNF-alpha-induced apoptosis

PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 111548 - 111548

MARIA G CASTRO; MARIANELA CANDOLFI; TJ WILSON; CHRISTOPHER PARAN; NEHA KAMRAN; CARL KOSCHMANN; MARIELA MORENO AYALA; HIKMAT ASSI; PEDRO R LOWENSTEIN

Adenoviral vector-mediated gene therapy for gliomas: coming of age

EXPERT OPINION ON BIOLOGICAL THERAPY; Lugar: London; Año: 2014 vol. 14 p. 1241 - 1257

SILVANA SANDRONE; GASTON REPOSSI; MARIANELA CANDOLFI; ALDO EYNARD

Essential fatty acids and gliomas: a critical review of experimental, clinical and epidemiological data

NUTRITION; Lugar: Amsterdam; Año: 2014 vol. 30 p. 1104 - 1109

MARIANELA CANDOLFI; KADER YAGIZ; MIA WIBOWO; GABRIELLE E ALZADEH; MARIANA PUNTEL; HOMAYON GHIASI; NEHA KAMRAN; CHRISTOPHER PARAN; PEDRO R LOWENSTEIN; MARIA G CASTRO

Temozolomide does not impair gene therapy-mediated antitumor immunity in syngeneic brain tumor models

CLINICAL CANCER RESEARCH; Lugar: Philadelphia; Año: 2014 vol. 20 p. 1555 - 1565

MARIANELA CANDOLFI; GWENDALYN D KING; KADER YAGIZ; JAMES F CURTIN; YOHEI MINEHARU; AKM GHULAM MUHAMMAD; DAVID FOULAD; KURT M KROEGER; NICK BARNETT; REGIS JOSIEN; PEDRO R LOWENSTEIN; MARIA G CASTRO

Plasmacytoid Dendritic Cells In The Tumor Microenvironment: Immune Targets For Glioma Therapeutics

NEOPLASIA; Lugar: confirmar; Año: 2012 vol. 14 p. 757 - 770

HIKMAT ASSI; MARIANELA CANDOLFI; GREGORY BAKER; YOHEI MINEHARU; PEDRO R LOWENSTEIN; MARIA G CASTRO

Gene Therapy for Brain Tumors: Basic Developments and Clinical Implementation.

NEUROSCIENCE LETTERS; Lugar: Amsterdam; Año: 2012 p. 71 - 77

YOHEI MINEHARU; AKM GHULAM MUHAMMAD; KADER YAGIZ; MARIANELA CANDOLFI; KURT M KROEGER; WEIDONG XIONG; MARIANA PUNTEL; PEDRO R LOWENSTEIN; MARIA G CASTRO

Reprogramming tumor infiltrating T cells using IL-2 and inhibiting NF-κB signaling improves the efficacy of immunotherapy in a preclinical brain cancer model.

NEUROTHERAPEUTICS; Lugar: Amsterdam; Año: 2012 p. 827 - 843

MARIA G CASTRO; MARIANELA CANDOLFI; KURT M KROEGER; GWENDALYN D KING; JAMES F CURTIN; KADER YAGIZ; YOHEI MINEHARU; HIKMAT ASSI; MIA WIBOWO; AKM GHULAM MUHAMMAD; DAVID FOULAD; MARIANA PUNTEL; PEDRO R LOWENSTEIN

Gene therapy and targeted toxins for glioma

CURRENT GENE THERAPY; Año: 2011 p. 155 - 180

MARIANELA CANDOLFI; KURT M KROEGER; WEIDONG XIONG; CHUNYAN LIU; MARIANA PUNTEL; KADER YAGIZ; AKM GHULAM MUHAMMAD; YOHEI MINEHARU; DAVID FOULAD; MIA WIBOWO; HIKMAT ASSI; GJ BAKER; PEDRO R LOWENSTEIN; MARIA G CASTRO

Targeted Toxins For Glioblastoma Multiforme: Pre-Clinical Studies And Clinical Implementation

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY; Año: 2011

MARIANELA CANDOLFI; JAMES F CURTIN; KADER YAGIZ; HIKMAT ASSI; MIA WIBOWO; GABRIELLE E ALZADEH; DAVID FOULAD; AKM GHULAM MUHAMMAD; SOFIA SALEHI; NAOMI KEECH; MARIANA PUNTEL; CHUNYAN LIU; NICHOLAS S SANDERSON; KURT M KROEGER; ROBERT DUNN; GISLAINE MARTINS; PEDRO R LOWENSTEIN; MARIA G CASTRO

B cells are critical to T-cell mediated anti-tumor immunity induced by a combined immune-stimulatory/conditionally cytotoxic therapy for glioblastoma

NEOPLASIA; Año: 2011 p. 947 - 960

MARIANA PUNTEL; AKM GHULAM MUHAMMAD; MARIANELA CANDOLFI; ALIREZA SALEM; KADER YAGIZ; CATHERINE FARROKI; KURT M KROEGER; WEIDONG XIONG; JAMES F CURTIN; CHUNYAN LIU; NIYATI S BONDALE; JONATHAN LERNER; ROBERT N PECHNICK; DONNA PALMER; PHILLIP NG; PEDRO R LOWENSTEIN; MARIA G CASTRO

A novel bi-cistronic high-capacity gutless adenovirus vector driving constitutive expression of HSV1-TK and Tet-inducible expression of Flt3L for glioma therapeutics

JOURNAL OF VIROLOGY; Año: 2010 vol. 84 p. 6007 - 6017

WEIDONG XIONG; MARIANELA CANDOLFI; CHUNYAN LIU; AKM GHULAM MUHAMMAD; KADER YAGIZ; MARIANA PUNTEL; PETER F MOORE; JULIE AVALOS; JOHN D YOUNG; DOROTHY KHAN; RANDY DONELSON; GE PLUHAR; JOHN R OHLFEST; KOLJIA WAWROWSKY; PEDRO R LOWENSTEIN; MARIA G CASTRO

Human Flt3L generates dendritic cells from canine peripheral blood precursors: implications for a dog glioma clinical trial.

PLOS ONE; Año: 2010 p. 11074 - 111085

AKM GHULAM MUHAMMAD; MARIANA PUNTEL; MARIANELA CANDOLFI; ALIREZA SALEM; KADER YAGIZ; CATHERINE FARROKI; KURT M KROEGER; WEIDONG XIONG; JAMES F CURTIN; CHUNYAN LIU; K LAWRENCE; NIYATI S BONDALE; JONATHAN LERNER; GJ BAKER; DAVID FOULAD; ROBERT N PECHNICK; DONNA PALMER; PHILLIP NG; PEDRO R LOWENSTEIN; MARIA G CASTRO

Study of the efficacy, biodistribution, and safety profile of therapeutic gutless adenovirus vectors as a prelude to a phase I clinical trial for glioblastoma

CLINICAL PHARMACOLOGY & THERAPEUTICS; Año: 2010 p. 204 - 213

MARIANELA CANDOLFI; WEIDONG XIONG; KADER YAGIZ; CHUNYAN LIU; AKM GHULAM MUHAMMAD; MARIANA PUNTEL; DAVID FOULAD; ALI ZADMEHR; GABRIELLE E ALZADEH; KURT M KROEGER; MATTHEW TESARFREUND; SHARON LEE; WALDEMAR DEBINSKI; D SAREEN; CLIVE N SVENDSEN; RONALD RODRIGUEZ; PEDRO R LOWENSTEIN; MARIA G CASTRO

Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2010 p. 20021 - 20026

KURT M KROEGER; AKM GHULAM MUHAMMAD; GJ BAKER; HIKMAT ASSI; MIA WIBOWO; WEIDONG XIONG; KADER YAGIZ; MARIANELA CANDOLFI; PEDRO R LOWENSTEIN; MARIA G CASTRO

Gene therapy and virotherapy: novel therapeutic approaches for brain tumors

DISCOVERY MEDICINE; Año: 2010 p. 293 - 304

AKM GHULAM MUHAMMAD; MARIANELA CANDOLFI; GWENDALYN D KING; KADER YAGIZ; DAVID FOULAD; YOHEI MINEHARU; KURT M KROEGER; KATERINE A TREUER; W S NICHOLS; NICHOLAS S SANDERSON; JIEPING YANG; MAXINE KHAYZNIKOV; N VAN ROOIJEN; PEDRO R LOWENSTEIN; MARIA G CASTRO

Antiglioma immunological memory in response to conditional cytotoxic/immune-stimulatory gene therapy: humoral and cellular immunity lead to tumor regression

CLINICAL CANCER RESEARCH; Año: 2009 p. 6113 - 6127

MARIANELA CANDOLFI; KADER YAGIZ; DAVID FOULAD; GABRIELLE E ALZADEH; MATTHEW TESARFREUND; AKM GHULAM MUHAMMAD; MARIANA PUNTEL; KURT M KROEGER; CHUNYAN LIU; SHARON LEE; JAMES F CURTIN; GWENDALYN D KING; JONATHAN LERNER; KANTSUAKI SATO; YOHEI MINEHARU; YOHEI MINEHARU; WEIDONG XIONG; PEDRO R LOWENSTEIN; MARIA G CASTRO

Release of HMGB1 in response to proapoptotic glioma killing strategies: efficacy and neurotoxicity

CLINICAL CANCER RESEARCH; Año: 2009 p. 4401 - 4414

JAMES F CURTIN; NAI-YOU LIU; MARIANELA CANDOLFI; WEIDONG XIONG; HIKMAT ASSI; KADER YAGIZ; MATTHEW R EDWARDS; KATHERINE S MICHELSEN; KURT M KROEGER; CHUNYAN LIU; AKM GHULAM MUHAMMAD; MARY CLARK; MOSHE ARDITI; BEGONYA COMIN-ANDUIX; ANTONI RIBAS; PEDRO R LOWENSTEIN; MARIA G CASTRO

HMGB1 mediates endogenous TLR2 activation and brain tumor regression

PLOS MEDICINE; Año: 2009 p. 10 - 24

MARIANELA CANDOLFI; KURT M KROEGER; AKM GHULAM MUHAMMAD; KADER YAGIZ; CATHERINE FARROKI; ROBERT N PECHNICK; PEDRO R LOWENSTEIN; MARIA G CASTRO

Gene therapy for brain cancer: combination therapies provide enhanced efficacy and safety

CURRENT GENE THERAPY; Año: 2009 p. 409 - 421

JAMES F CURTIN; MARIANELA CANDOLFI; TAMER M FAKHOURI; CHUNYAN LIU; ANDREW ALDEN; MATTHEW R EDWARDS; PEDRO R LOWENSTEIN; MARIA G CASTRO

Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials

PLOS ONE; Año: 2008 p. 1983 - 2000

GWENDALYN D KING; AKM GHULAM MUHAMMAD; CHUNYAN LIU; KURT M KROEGER; CJ BRESEE; CM MANALO; MARIANELA CANDOLFI; ROBERT N PECHNICK; PEDRO R LOWENSTEIN; MARIA G CASTRO

Flt3L in combination with HSV1-TK-mediated gene therapy reverses brain tumor-induced behavioral deficits

MOLECULAR THERAPY (PRINT); Año: 2008 p. 682 - 690

WEIDONG XIONG; MARIANELA CANDOLFI; KURT M KROEGER; MARIANA PUNTEL; SONALI MONDKAR; DANIEL LAROCQUE; CHUNYAN LIU; JAMES F CURTIN; DONNA PALMER; PHILLIP NG; PEDRO R LOWENSTEIN; MARIA G CASTRO

Immunization against the transgene but not the TetON switch reduces expression from gutless adenoviral vectors in the brain

MOLECULAR THERAPY (PRINT); Año: 2008 p. 343 - 351

JAMES F CURTIN; MARIANELA CANDOLFI; WEIDONG XIONG; PEDRO R LOWENSTEIN; MARIA G CASTRO

Turning the gene tap off; implications of regulating gene expression for cancer therapeutics

MOLECULAR CANCER THERAPEUTICS; Año: 2008 p. 439 - 448

GWENDALYN D KING; AKM GHULAM MUHAMMAD; JAMES F CURTIN; CARLOS BARCIA; MARIANA PUNTEL; CHUNYAN LIU; SN HONIG; MARIANELA CANDOLFI; SONALI MONDKAR; PEDRO R LOWENSTEIN; MARIA G CASTRO

Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model.

NEURO-ONCOLOGY; Año: 2007 p. 19 - 31

CARLOS BARCIA; MARIANO JIMENEZ-DALMARONI; KURT M KROEGER; MARIANA PUNTEL; AJ RAPAPORT; GWENDALYN D KING; STEVEN A JOHNSON; CHUNYAN LIU; WEIDONG XIONG; MARIANELA CANDOLFI; SONALI MONDKAR; PHILLIP NG; DONNA PALMER; MARIA G CASTRO; PEDRO R LOWENSTEIN

One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: clinical implications

MOLECULAR THERAPY (PRINT); Año: 2007 p. 2154 - 2163

MARIANELA CANDOLFI; JAMES F CURTIN; WS NICHOLS; AKM GHULAM MUHAMMAD; GWENDALYN D KING; GE PLUHAR; EA MCNIEL; JOHN R OHLFEST; ANDREW B FREESE; PETER F MOORE; JONATHAN LERNER; PEDRO R LOWENSTEIN; MARIA G CASTRO

Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression

JOURNAL OF NEURO-ONCOLOGY.; Año: 2007 p. 133 - 148

MARIANELA CANDOLFI; GE PLUHAR; KURT M KROEGER; MARIANA PUNTEL; JAMES F CURTIN; CARLOS BARCIA; AKM GHULAM MUHAMMAD; WEIDONG XIONG; CHUNYAN LIU; SONALI MONDKAR; W KUOY; T KANG; EA MCNIEL; ANDREW B FREESE; JOHN R OHLFEST; PETER F MOORE; DONNA PALMER; PHILLIP NG; JOHN D YOUNG; PEDRO R LOWENSTEIN; MARIA G CASTRO

Optimization of adenoviral vector-mediated transgene expression in the canine brain in vivo, and in canine glioma cells in vitro

NEURO-ONCOLOGY; Año: 2007 p. 245 - 258

MARIANELA CANDOLFI; KURT M KROEGER; GE PLUHAR; CHUNYAN LIU; CARLOS BARCIA; JOSEE BERGERON; MARIANA PUNTEL; JAMES F CURTIN; EA MCNIEL; ANDREW B FREESE; JOHN R OHLFEST; PETER F MOORE; W KUOY; PEDRO R LOWENSTEIN; MARIANELA CANDOLFI

Adenoviral-mediated gene transfer into the canine brain in vivo

NEUROSURGERY.; Año: 2007 p. 167 - 177

CARLOS BARCIA; CLIAIRE E THOMAS; JAMES F CURTIN; GWENDALYN D KING; KOLJIA WAWROWSKY; MARIANELA CANDOLFI; WEIDONG XIONG; CHUNYAN LIU; KURT M KROEGER; O BOYER; J KUPIEC-WEGLINSKI; DAVID KLATZMANN; MARIA G CASTRO; MARIA G CASTRO

In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain

JOURNAL OF EXPERIMENTAL MEDICINE; Año: 2006 p. 2095 - 2107

MARIANELA CANDOLFI; JAMES F CURTIN; WEIDONG XIONG; KURT M KROEGER; CHUNYAN LIU; ALTAN RENTSENDORJ; HASMIK AGDJANIAN; LALI MEDINA-KAUWE; DONNA PALMER; PHILLIP NG; PEDRO R LOWENSTEIN; MARIA G CASTRO

Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells

MOLECULAR THERAPY (PRINT); Año: 2006 p. 371 - 381

MARIANELA CANDOLFI; GABRIELA JAITA; DANIEL PISERA; LUCIANA FERRARI; CARLOS BARCIA; CHUNYAN LIU; MARIA G CASTRO; ADRIANA SEILICOVICH

Adenoviral vectors encoding tumor necrosis factor-alpha and FasL induce apoptosis of normal and tumoral anterior pituitary cells

JOURNAL OF ENDOCRINOLOGY; Año: 2006 p. 681 - 690

WEIDONG XIONG; S GOVERDANA; SANDRA A SCIASCIA; MARIANELA CANDOLFI; JM ZIRGER; CARLOS BARCIA; JAMES F CURTIN; GWENDALYN D KING; GABRIELA JAITA; CHUNYAN LIU; KURT M KROEGER; PHILLIP NG; DONNA PALMER; HASMIK AGDJANIAN; LALI MEDINA-KAUWE; PEDRO R LOWENSTEIN; MARIA G CASTRO

Regulatable gutless adenovirus vectors sustain inducible transgene expression in the brain in the presence of an immune response against adenoviruses

JOURNAL OF VIROLOGY; Año: 2006 p. 1685 - 1705

GABRIELA JAITA; MARIANELA CANDOLFI; VERONICA ZALDIVAR; SANDRA ZARATE; LUCIANA FERRARI; DANIEL PISERA; MARIA G CASTRO; ADRIANA SEILICOVICH

Estrogens up-regulate the Fas/FasL apoptotic pathway in lactotropes

ENDOCRINOLOGY; Año: 2005 p. 4737 - 4744

SUMIA ALI; GWENDALYN D KING; JAMES F CURTIN; MARIANELA CANDOLFI; WEIDONG XIONG; CHUNYAN LIU; MARIANA PUNTEL; Q CHENG; J PRIETO; ANTONI RIBAS; J KUPIEC-WEGLINSKI; N VAN ROOIJEN; H LASSMAN; PEDRO R LOWENSTEIN; MARIA G CASTRO

Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model

CANCER RESEARCH; Año: 2005 p. 7194 - 7204

MARIANELA CANDOLFI; GABRIELA JAITA; VERONICA ZALDIVAR; SANDRA ZARATE; LUCIANA FERRARI; DANIEL PISERA; MARIA G CASTRO; ADRIANA SEILICOVICH

Progesterone antagonizes the permissive action of estradiol on tumor necrosis factor-alpha-induced apoptosis of anterior pituitary cells

ENDOCRINOLOGY; Año: 2005 p. 736 - 743

S GOVERDANA; MARIANA PUNTEL; WEIDONG XIONG; JM ZIRGER; CARLOS BARCIA; JAMES F CURTIN; EB SOFFER; SONALI MONDKAR; GWENDALYN D KING; J HU; SANDRA A SCIASCIA; MARIANELA CANDOLFI; DS GREENGOLD; PEDRO R LOWENSTEIN; MARIA G CASTRO

Regulatable gene expression systems for gene therapy applications: progress and future challenges

MOLECULAR THERAPY (PRINT); Año: 2005 p. 189 - 211

JAMES F CURTIN; GWENDALYN D KING; MARIANELA CANDOLFI; RB GREENO; KURT M KROEGER; PEDRO R LOWENSTEIN; MARIA G CASTRO

Combining cytotoxic and immune-mediated gene therapy to treat brain tumors

Current Topics in Medicinal Chemistry; Año: 2005 p. 1151 - 1170

GWENDALYN D KING; JAMES F CURTIN; MARIANELA CANDOLFI; KURT M KROEGER; PEDRO R LOWENSTEIN; MARIA G CASTRO

Gene therapy and targeted toxins for glioma

CURRENT GENE THERAPY; Año: 2005 p. 535 - 557

ADRIANA SEILICOVICH; DANIEL PISERA; SANDRA A SCIASCIA; MARIANELA CANDOLFI; MARIANA PUNTEL; WEIDONG XIONG; GABRIELA JAITA; MARIA G CASTRO

Gene therapy for pituitary tumors

CURRENT GENE THERAPY; Año: 2005 p. 559 - 572

MARIANELA CANDOLFI; GABRIELA JAITA; VERONICA ZALDIVAR; SANDRA ZARATE; DANIEL PISERA; ADRIANA SEILICOVICH

Tumor necrosis factor-alpha-induced nitric oxide restrains the apoptotic response of anterior pituitary cells

NEUROENDOCRINOLOGY; Año: 2004 p. 83 - 91

DANIEL PISERA; MARIANELA CANDOLFI; SANTIAGO NAVARRA; JIMENA FERRARIS; VERONICA ZALDIVAR; GABRIELA JAITA; MARIA G CASTRO; ADRIANA SEILICOVICH

Estrogens sensitize anterior pituitary gland to apoptosis

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM; Año: 2004 p. 767 - 771

DANIEL PISERA; MARIANELA CANDOLFI; ANDREA DE LAURENTIIS; ADRIANA SEILICOVICH

Characterization of tachykinin NK2 receptor in the anterior pituitary gland

LIFE SCIENCES; Año: 2003 p. 2421 - 2432

ANDREA DE LAURENTIIS; MARIANELA CANDOLFI; DANIEL PISERA; ADRIANA SEILICOVICH

Effects of lipopolysaccharide on neurokinin A content and release in the hypothalamic-pituitary axis

REGULATORY PEPTIDES; Año: 2003 p. 91 - 95

ANDREA DE LAURENTIIS; DANIEL PISERA; CARLA CARUSO; MARIANELA CANDOLFI; CLAUDIA MOHN; VALERIA RETTORI; ADRIANA SEILICOVICH

Lipopolysaccharide- and tumor necrosis factor-alpha-induced changes in prolactin secretion and dopaminergic activity in the hypothalamic-pituitary axis

NEUROIMMUNOMODULATION.; Año: 2002 p. 31 - 39

MARIANELA CANDOLFI; VERONICA ZALDIVAR; ANDREA DE LAURENTIIS; GABRIELA JAITA; DANIEL PISERA; ADRIANA SEILICOVICH

TNF-alpha induces apoptosis of lactotropes from female rats

ENDOCRINOLOGY; Año: 2002 p. 3611 - 3817

SUSANA THEAS; ANDREA DE LAURENTIIS; MARIANELA CANDOLFI; SL LOPEZ; AECARRASCO; VERONICA ZALDIVAR; ADRIANA SEILICOVICH

Nitric oxide mediates the inhibitory effect of tumor necrosis factor-alpha on prolactin release

NEUROENDOCRINOLOGY; Año: 2001 p. 82 - 86