CASTILLO, ANA FERNANDA; PODEROSO, CECILIA; MALOBERTI, PAULA MARIANA; CORNEJO MACIEL, FABIANA; MORI SEQUEIROS GARCIA, MARÍA MERCEDES; ORLANDO, ULISES DANIEL; MELE, PABLO; BENZO, YANINA; DATTILO, MELINA ANDREA; PRADA, JESICA; QUEVEDO, LUCIANO; BELLUNO, MATÍAS; PAZ, CRISTINA; PODESTA, ERNESTO JORGE

Specific cellular microenvironments for spatiotemporal regulation of StAR and steroid synthesis

JOURNAL OF ENDOCRINOLOGY; Año: 2024 vol. 261

MORI SEQUEIROS GARCIA MM.; PAZ, CRISTINA; CASTILLO, ANA F.; BENZO, YANINA; BELLUNO, MATÍAS; BALCÁZAR MARTÍNEZ, A; MALOBERTI, PAULA; CORNEJO MACIEL, FABIANA; PODEROSO, CECILIA

New insights into signal transduction pathways in adrenal steroidogenesis: role of mitochondrial fusion, lipid mediators, and MAPK phosphatases

Frontiers in Endocrinology; Lugar: Laussane; Año: 2023 vol. 14

CASTILLO, ANA F.; ORLANDO, ULISES D.; MALOBERTI, PAULA M.; PRADA, JESICA G.; DATTILO, MELINA A.; SOLANO, ANGELA R.; BIGI, MARÍA M.; RÍOS MEDRANO, MAYRA A.; TORRES, MARÍA T.; INDO, SEBASTIÁN; CAROCA, GRACIELA; CONTRERAS, HECTOR R.; MARELLI, BELKIS E.; SALINAS, FACUNDO J.; SALVETTI, NATALIA R.; ORTEGA, HUGO H.; LORENZANO MENNA, PABLO; SZAJNMAN, SERGIO; GOMEZ, DANIEL E.; RODRÍGUEZ, JUAN B.; PODESTA, ERNESTO J.

New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis

CELL. MOLEC. LIFE SCIEN.; Año: 2021 vol. 78 p. 2893 - 2910

ORLANDO, ULISES DANIEL; CASTILLO, ANA FERNANDA; MEDRANO, MAYRA AGUSTINA RÍOS; SOLANO, ANGELA ROSARIA; MALOBERTI, PAULA MARIANA; PODESTA, ERNESTO JORGE

Acyl-CoA synthetase-4 is implicated in drug resistance in breast cancer cell lines involving the regulation of energy-dependent transporter expression

BIOCHEMICAL PHARMACOLOGY; Año: 2019 vol. 159 p. 52 - 63

HELFENBERGER, KATIA E.; CASTILLO, ANA F.; MELE, PABLO G.; FIORE, ANA; HERRERA, LUCÍA; FINOCCHIETTO, PAOLA; PODESTÁ, ERNESTO J.; PODEROSO, CECILIA

Angiotensin II stimulation promotes mitochondrial fusion as a novel mechanism involved in protein kinase compartmentalization and cholesterol transport in human adrenocortical cells

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2019 vol. 192

DATTILO, MELINA A.; BENZO, YANINA; HERRERA, LUCÍA M.; PRADA, JESICA G.; CASTILLO, ANA F.; ORLANDO, ULISES D.; PODESTA, ERNESTO J.; MALOBERTI, PAULA M.

Regulatory mechanisms leading to differential Acyl-CoA synthetase 4 expression in breast cancer cells

Scientific Reports; Lugar: Londres; Año: 2019 vol. 9 p. 10324 - 10337

PAZ, CRISTINA; CORNEJO MACIEL, FABIANA; GOROSTIZAGA, ALEJANDRA; CASTILLO, ANA FERNANDA; MORI SEQUEIROS GARCIA, MM.; MALOBERTI, PAULA; ORLANDO, ULISES; MELE, PABLO; PODEROSO, CECILIA; PODESTÁ, ERNESTO J

Role of Protein Phosphorylation and Tyrosine Phosphatases in the Adrenal Regulation of Steroid Synthesis and Mitochondrial Function.

Frontiers in endocrinology; Año: 2016 vol. 7 p. 1 - 15

CASTILLO AF,; ORLANDO U; HELFENBERGER KE; PODEROSO C.; PODESTÁ EJ

The role of mitochondrial fusion and StAR phosphorylation in the regulation of StAR activity and steroidogenesis

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Lugar: Amsterdam; Año: 2015 vol. 408 p. 73 - 79

CASTILLO, A.F.; ORLANDO, U.; LÓPEZ, P.; SOLANO, A.R.; MALOBERTI, P.M.; PODESTÁ, E.J.

Gene Expression Profile and Signaling Pathways in MCF-7 Breast Cancer Cells Mediated by Acyl-Coa Synthetase 4 Overexpression

Transcriptomics Open Access; Año: 2015 vol. 3 p. 1 - 9

ORLANDO, U.; CASTILLO, A.F.; DATTILO, M.; SOLANO, A.R.; MALOBERTI, P.M.; PODESTÁ, E.J.

Acyl-CoA synthetase-4, a new regulator of mTOR and a potential therapeutic target for enhanced estrogen receptor function in receptor-positive and -negative breast cancer.

Oncotarget; Lugar: New York; Año: 2015 vol. 6 p. 42632 - 42650

DUARTE, ALEJANDRA; CASTILLO, ANA FERNANDA; PODESTÁ, ERNESTO J; PODEROSO, CECILIA

Mitochondrial Fusion and ERK Activity Regulate Steroidogenic Acute Regulatory Protein Localization in Mitochondria

PLOS ONE; Lugar: San Francisco; Año: 2014 vol. 9 p. 1 - 12

ANA FERNANDA CASTILLO; JINJIANG FAN; VASSILIOS PAPADOPOULOS; ERNESTO J. PODESTA

Hormone-dependent expression of a steroidogenic acute regulatory protein natural antisense transcript in MA-10 mouse tumor Leydig cells

PLOS ONE; Lugar: San Francisco; Año: 2011 vol. 6 p. 1 - 14

CASTILLO, ANA FERNANDA; CASTILLA, ROCÍO; DUARTE, ALEJANDRA; MELE, PABLO; ORLANDO, ULISES; KARLÉS, CRISTINA; NEUMAN, ISABEL; DI CÓNSOLI, HERNÁN; PODEROSO, CECILIA; SOLANO, ANGELA; FINKIELSTEIN, CARLA; MALOBERTI, PAULA; CORNEJO MACIEL, FABIANA; PAZ, CRISTINA; PODESTÁ, ERNESTO J

Intramitochondrial arachidonic acid as regulator of two different cellular functions: steroid biosynthesis and tumor cell proliferation

Current Trends in Endocrinology; Año: 2008 vol. 3 p. 57 - 75

CASTILLA, ROCÍO; GADALETA, MARIANA; CASTILLO, ANA FERNANDA; DUARTE, ALEJANDRA; NEUMAN, ISABEL; PAZ, CRISTINA; CORNEJO MACIEL, FABIANA; PODESTÁ, ERNESTO J

New Enzymes Involved in the Mechanism of Action of Epidermal Growth Factor in a Clonal Strain of Leydig Tumor Cells.

ENDOCRINOLOGY; Año: 2008 vol. 149 p. 3743 - 3752

DUARTE, ALEJANDRA; CASTILLO, ANA FERNANDA; CASTILLA, ROCÍO; MALOBERTI, PAULA; PAZ, CRISTINA; PODESTÁ, ERNESTO J; CORNEJO MACIEL, FABIANA

An arachidonic acid generation/export system involved in the regulation of cholesterol transport in mitochondria of steroidogenic cells

FEBS LETTERS; Lugar: Holanda; Año: 2007 vol. 581 p. 4023 - 4028

MALOBERTI, PAULA; CORNEJO MACIEL, FABIANA; CASTILLO, ANA FERNANDA; CASTILLA, ROCÍO; DUARTE, ALEJANDRA; TOLEDO, FERNANDA; MEULI, FLAVIA; MELE, PABLO; PAZ, CRISTINA; PODESTÁ, ERNESTO J

Enzymes involved in arachidonic acid release in adrenal and Leydig cells.

MOLECULAR AND CELLULAR ENDOCRINOLOGY.; Año: 2007 vol. 265 p. 113 - 120

CASTILLO, ANA FERNANDA; CORNEJO MACIEL, FABIANA; CASTILLA, ROCÍO; DUARTE, ALEJANDRA; MALOBERTI, PAULA; PAZ, CRISTINA; PODESTÁ, ERNESTO J

cAMP increases mitochondrial cholesterol transport through the induction of arachidonic acid release inside this organelle in Leydig cells

FEBS JOURNAL; Lugar: Inglaterra; Año: 2006 vol. 273 p. 5011 - 5021

CANO, FLORENCIA; PODEROSO, CECILIA; CORNEJO MACIEL, FABIANA; CASTILLA, ROCÍO; MALOBERTI, PAULA; CASTILLO, FERNANDA; NEUMAN, ISABEL; PAZ, CRISTINA; PODESTÁ, ERNESTO J

Protein tyrosine phosphatases regulate arachidonic acid release, StAR induction and steroidogenesis acting on a hormone-dependent arachidonic acid-preferring acyl-CoA synthetase

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Lugar: Inglaterra; Año: 2006 vol. 99 p. 197 - 202

MALOBERTI, PAULA; CASTILLA, ROCÍO; CASTILLO, FERNANDA; CORNEJO MACIEL, FABIANA; MÉNDEZ, CARLOS F.; PAZ, CRISTINA; PODESTÁ, ERNESTO J

Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis.

FEBS JOURNAL; Año: 2005 vol. 272 p. 1804 - 1814

CORNEJO MACIEL, FABIANA; MALOBERTI, PAULA; NEUMAN, ISABEL; CANO, FLORENCIA; CASTILLA, ROCÍO; CASTILLO, FERNANDA; PAZ, CRISTINA; PODESTÁ, ERNESTO J

An arachidonic acid-preferring acyl-CoA synthetase is a hormone-dependent and obligatory protein in the signal transduction pathway of steroidogenic hormones

JOURNAL OF MOLECULAR ENDOCRINOLOGY; Lugar: Inglaterra; Año: 2005 vol. 34 p. 655 - 666

CASTILLO, FERNANDA; CANO, FLORENCIA; MALOBERTI, PAULA; CASTILLA, ROCÍO; NEUMAN, ISABEL; PODEROSO, CECILIA; PAZ, CRISTINA; PODESTÁ, ERNESTO J; CORNEJO MACIEL, FABIANA

Tyrosine phosphates act on steroidogenesis through the activation of arachidonic acid release.

ENDOCRINE RESEARCH; Año: 2004 vol. 30 p. 623 - 627

CASTILLA, ROCÍO; MALOBERTI, PAULA; CASTILLO, FERNANDA; DUARTE, ALEJANDRA; CANO, FLORENCIA; CORNEJO MACIEL, FABIANA; NEUMAN, ISABEL; MÉNDEZ, CARLOS F.; PAZ, CRISTINA; PODESTÁ, ERNESTO J

Arachidonic acid regulation of steroid synthesis: new partners in the signaling pathway of steroidogenic hormones.

ENDOCRINE RESEARCH; Año: 2004 vol. 30 p. 599 - 606