INVESTIGADORES
VENTURA Alejandra Cristina
congresos y reuniones científicas
Título:
A Dynamics Perspective on Modularity in Biomolecular Networks
Autor/es:
PENG JIANG; ALEJANDRA C VENTURA; SOFIA D MERAJVER; ALEXANDER J NINFA; DOMITILLA DEL VECCHIO
Lugar:
Edinburgh
Reunión:
Conferencia; The 11th International Conference on Systems Biology; 2010
Institución organizadora:
International Society for Systems Biology
Resumen:
Retroactivity is an impedance-like effect found at the interconnection of biomolecular systems. Just like impedance in electrical circuits, it causes the behavior of a system to change upon interconnection. In this abstract, we describe theoretical and experimental work that characterizes the effects of retroactivity on the dynamic behavior of signal transduction modules. We further show how these modules can be re-engineered to attain insulation from retroactivity.
