MARRONE, JUAN IGNACIO; SEPULCHRE, JACQUES-ALEXANDRE; VENTURA, ALEJANDRA C.

A nested bistable module within a negative feedback loop ensures different types of oscillations in signaling systems

Scientific Reports; Lugar: Londres; Año: 2023 vol. 13 p. 1 - 19

JUAN IGNACIO MARRONE; JACQUES-A. SEPULCHRE; ALEJANDRA C VENTURA

Pseudo-nullclines enable the analysis and prediction of signaling model dynamics

Frontiers in Cell and Developmental Biology; Año: 2023 vol. 11

SZEMERE, JULIANA REVES; ROTSTEIN, HORACIO G.; VENTURA, ALEJANDRA C.

Frequency-preference response in covalent modification cycles under substrate sequestration conditions

npj Systems Biology and Applications; Lugar: Londres; Año: 2021 vol. 7

SEVLEVER, FEDERICO; DI BELLA, JUAN PABLO; VENTURA, ALEJANDRA C.

Discriminating between negative cooperativity and ligand binding to independent sites using pre-equilibrium properties of binding curves

PLOS Computational Biology; Lugar: San Francisco; Año: 2020 vol. 16

TENENBAUM, DEBORA; MARRONE, JUAN IGNACIO; GRECCO, HERNÁN E.; VENTURA, ALEJANDRA C.

Robustness in spatially driven bistability in signaling systems

Scientific Reports; Lugar: Londres; Año: 2020 vol. 10

WAISMAN, ARIEL; SEVLEVER, FEDERICO; ELÍAS COSTA, MARTÍN; COSENTINO, MARÍA SOLEDAD; MIRIUKA, SANTIAGO G.; VENTURA, ALEJANDRA C.; GUBERMAN, ALEJANDRA S.

Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency

Scientific Reports; Lugar: London; Año: 2019 vol. 9

DI-BELLA, JUAN PABLO; COLMAN-LERNER, ALEJANDRO; VENTURA, ALEJANDRA C.

Properties of cell signaling pathways and gene expression systems operating far from steady-state

Scientific Reports; Lugar: Londres; Año: 2018 vol. 8

ALTSZYLER, EDGAR; VENTURA, ALEJANDRA C.; COLMAN-LERNER, ALEJANDRO; CHERNOMORETZ, ARIEL

Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations

PLOS ONE; Año: 2017 vol. 12

SIMONA CATOZZI; JUAN PABLO DI BELLA; ALEJANDRA C VENTURA; JACQUES-A. SEPULCHRE

Signaling cascades transmit information downstream and upstream but unlikely simultaneously

BMC SYSTEMS BIOLOGY; Lugar: Londres; Año: 2016

EDGAR ALTSZYLER; ALEJANDRA C VENTURA; ALEJANDRO COLMAN-LERNER; ARIEL CHERNOMORETZ

Impact of upstream and downstream constraints on a signaling module's ultrasensitivity

PHYSICAL BIOLOGY; Lugar: Londres; Año: 2014 vol. 11 p. 66003 - 66017

VENTURA AC; ALAN BUSH; GUSTAVO VASEN; MATIAS GOLDIN; BRIANNE BURKINSHAW; NIRVEEK BHATTACHARJEE; ALBERT FOLCH; ROGER BRENT; ARIEL CHERNOMORETZ; ALEJANDRO COLMAN-LERNER

Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2014 vol. 111 p. 3860 - 3869

JACQUES-A. SEPULCHRE; ALEJANDRA C VENTURA

Intrinsic feedbacks in MAPK signaling cascades lead to bistability and oscillations

ACTA BIOTHEORETICA; Lugar: Berlin; Año: 2013 vol. 61 p. 59 - 78

PENG JIANG; ALEJANDRA C VENTURA; EDUARDO D SONTAG; SOFIA D MERAJVER; ALEXANDER J NINFA; DOMITILLA DEL VECCHIO

Response to Comment on “‘Load-Induced Modulation of Signal Transduction Networks’: Reconciling Ultrasensitivity with Bifunctionality?”

SCIENCE SIGNALING; Lugar: Washington DC; Año: 2012 vol. 5 p. 1 - 2

PENG JIANG; ALEJANDRA C VENTURA; ALEXANDER J NINFA

Characterization of the reconstituted UTase/UR-PII-NRII-NRI bicyclic signal transduction system that controls the transcription of nitrogen-regulated (Ntr) genes in Escherichia coli.

BIOCHEMISTRY; Lugar: Washington; Año: 2012 vol. 51 p. 9045 - 9047

JACQUES-A. SEPULCHRE; SOFIA D MERAJVER; ALEJANDRA C VENTURA

Retroactive signaling in short signaling pathways

PLOS ONE; Lugar: San Francisco; Año: 2012 vol. 7 p. 40806 - 40806

ME GONZALEZ; ML DUPRIE; H KRUEGER ; SD MERAJVER ; ALEJANDRA C VENTURA; KA TOY; CG KLEER

Histone Methyltransferase EZH2 Induces Akt-Dependent Genomic Instability and BRCA1 Inhibition in Breast Cancer

CANCER RESEARCH; Año: 2011 vol. 71 p. 2360 - 2370

HR OSSAREH; ALEJANDRA C VENTURA; SD MERAJVER; DOMITILLA DEL VECCHIO

Long signaling cascades tend to attenuate retroactivity

BIOPHYSICAL JOURNAL; Año: 2011 vol. 100 p. 1617 - 1626

PENG JIANG; ALEJANDRA C VENTURA; EDUARDO D SONTAG; SOFIA D MERAJVER; ALEXANDER J NINFA; DOMITILLA DEL VECCHIO

Load-induced modulation of signal transduction networks

SCIENCE SIGNALING; Año: 2011 vol. 4 p. 1 - 10

DEVIN T ROSENTHAL; HARISH IYER; SILVIA ESCUDERO; LIWEI BAO; ZHIFEN WU; ALEJANDRA C VENTURA; CELINA G KLEER; ELLEN M ARRUDA; KRISHNA GARIKIPATI; SOFIA D MERAJVER

p38{gamma} Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior

CANCER RESEARCH; Lugar: Philadelphia; Año: 2011 vol. 71 p. 6338 - 6349

ALEJANDRA C VENTURA; MICHELLE WYNN; JACQUES-A. SEPULCHRE; HECTOR J GARCIA; SOFIA D MERAJVER

Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity

BMC SYSTEMS BIOLOGY; Lugar: London; Año: 2011 vol. 5 p. 1 - 15

LUCIANA BRUNO; GUILLERMO SOLOVEY; ALEJANDRA C VENTURA; SHEILA DARGAN; IAN PARKER; SILVINA PONCE DAWSON

Quantifying calcium fluxes underlying calcium puffs in Xenopus laevis oocytes

CELL CALCIUM.; Lugar: Amsterdam; Año: 2010 vol. 47 p. 273 - 286

ALEJANDRA C VENTURA; PENG JIANG; LAUREN VAN WASSENHOVE; DOMITILLA DEL VECCHIO; SOFIA D MERAJVER; ALEXANDER J NINFA

Signaling properties of a covalent modification cycle are altered by a downstream target

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2010 vol. 107 p. 10032 - 10037

KSM VAREDI; ALEJANDRA C VENTURA; SOFIA D MERAJVER; XN LIN

Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation

PLOS ONE; Año: 2010 vol. 5 p. 14029 - 14029

DEVIN T ROSENTHAL; HARISH IYER; SILVIA ESCUDERO; ALEJANDRA C VENTURA; ELLEN M ARRUDA; KRISHNA GARIKIPATI; SOFIA D MERAJVER

From in vitro to in silico and back again: Using biological and mathematical synergy to decipher breast cancer cell motility

2010 Annual International Conference of the IEEE Engineering in Medicine and Biology; Año: 2010 vol. 2010 p. 3261 - 3264

BAO L; GORIN MA; ZHANG M; VENTURA AC; POMERANTZ SD; MERAJVER SD; TEKNOS TN; MAPP AK; PAN Q

Preclinical development of a bifunctional cancer cell homing, PKCepsilon inhibitory peptide for the treatment of head and neck cancer

CANCER RESEARCH; Año: 2009 vol. 69 p. 5829 - 5834

ALEJANDRA C VENTURA; TRACHETTE L JACKSON; SOFIA D MERAJVER

On the role of cell signaling models in cancer research

CANCER RESEARCH; Año: 2009 p. 400 - 402

ALEJANDRA C VENTURA; SOFIA D MERAJVER

Genetic determinants of aggressive breast cancer

Annual Review of Medicine; Lugar: Palo Alto, CA; Año: 2008 vol. 59 p. 199 - 212

ALEJANDRA C VENTURA; JACQUES-A. SEPULCHRE; SOFIA D MERAJVER

A hidden feedback in signaling cascades is revealed

PLoS Computational Biology; Año: 2008 vol. 21 p. 1 - 14

GONZALEZ ME; LI X; TOY K; DUPRIE M; ALEJANDRA C VENTURA; BANERJEE M; LJUNGMAN M; MERAJVER SD; KLEER CG

Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1

ONCOGENE; Año: 2008 vol. 1 p. 1 - 11

ALEJANDRA C VENTURA; LUCIANA BRUNO; SILVINA PONCE DAWSON

Simple data-driven models of intracellular calcium dynamics with predictive power

PHYSICAL REVIEW E - STATISTICAL PHYSICS, PLASMAS, FLUIDS AND RELATED INTERDISCIPLINARY TOPICS; Año: 2006 vol. 74 p. 1 - 11

ALEJANDRA C VENTURA; JAMES SNEYD

Calcium oscillations and waves generated by multiple release mechanisms in pancreatic acinar cells

BULLETIN OF MATHEMATICAL BIOLOGY; Año: 2006 vol. 68 p. 2205 - 2231

ALEJANDRA C VENTURA; LUCIANA BRUNO; ANGELO DEMURO; IAN PARKER; SILVINA PONCE DAWSON

A model-independent algorithm to derive Ca2+ fluxes underlying local cytosolic Ca2+ transients

BIOPHYSICAL JOURNAL; Año: 2005 vol. 88 p. 2403 - 2421

ALEJANDRA C VENTURA; LUCIANA BRUNO; SILVINA PONCE DAWSON

Probing a reduced equation for intracellular calcium dynamics

PHYSICA A - STATISTICAL AND THEORETICAL PHYSICS; Año: 2004 vol. 342 p. 281 - 287

DAMIAN E STRIER; ALEJANDRA C VENTURA; SILVINA PONCE DAWSON

Saltatory and Continuous Calcium Waves and the Rapid Buffering Approximation

BIOPHYSICAL JOURNAL; Año: 2003 vol. 85 p. 3575 - 3586

ALEJANDRA C VENTURA; BERNARDO G MINDLIN; SILVINA PONCE DAWSON

Generic two-variable model of excitability

PHYSICAL REVIEW E - STATISTICAL PHYSICS, PLASMAS, FLUIDS AND RELATED INTERDISCIPLINARY TOPICS; Año: 2002 vol. 65 p. 1 - 7

ALEJANDRA C VENTURA; SILVINA PONCE DAWSON

Análisis de eventos elementales en las señales intracelulares de calcio

Anales AFA; Lugar: Rosario; Año: 2002 vol. 13 p. 194 - 196

ALEJANDRA C VENTURA; SILVINA PONCE DAWSON

Modelos de excitabilidad

Anales AFA; Lugar: Buenos Aires; Año: 2001 vol. 12 p. 168 - 171

NAIRA PINTO; ALEJANDRA C VENTURA; ANDRES MOREIRA

Metapopulational Structure and Community Assemblage in an ECHO Model

Student Papers Santa Fe Complex Systems Summer School 2001; Lugar: Santa Fe, New Mexico, USA; Año: 2001 vol. 2001 p. 1 - 10