Inhibition of Helicobacter pylori and Its Associated Urease by Two RegionalPlants of San Luis Argentina.

A.G. SALINAS IBÁÑEZ, ; A.C. ARISMENDI SOSA, ; F.F. FERRAMOLA; J. PAREDES, ; G. WENDEL, ; A.O. MARIA ; A.E. VEGA

. International Journal of Current Microbiology and Applied Sciences

Exellent Publishers

Año: 2017 vol. 6 p. 2097 - 2106

2319-7706

The search of alternative anti-Helicobacter pylori agents obtained mainly of medicinal plants is a scientific area of great interest. The antimicrobial effects of Litrahea molleoides and Aristolochia argentina extracts against sensible and resistant H. pylori strains, were evaluated in vitro. Also, the urease inhibition activity and the effect on the ureA gene expression mRNA was evaluated. The L. molleoides and A. argentinae extracts showed antimicrobial activity against all strains assayed. Regardless of the extract assayed adecrease of viable count of approximately 2 log units on planktonic cell or established biofilms in H. pylori strains respect to the control was observed (p