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Concomitant inhibition of PPARγ and mTORC1 induces the differentiation of human monocytes into highly immunogenic dendritic cells

Cell Reports; Año: 2023 vol. 42

ELIZAGARAY, MAIA LINA; MAZITELLI, IGNACIO; PONTORIERO, ANDREA; BAUMEISTER, ELSA; DOCENA, GUILLERMO; RAIMONDI, CLEMENTE; CORREGER, ENRIQUE; RUMBO, MARTIN

Lidocaine reinforces the anti-inflammatory action of dexamethasone on myeloid and epithelial cells activated by inflammatory cytokines or SARS-CoV-2 infection

Biomedical Journal; Año: 2023 vol. 46 p. 81 - 92

DUARTE A; CRUCES, L; NABAES JODAR, MS; ALVAREZ, DIEGO; MONZANI, CECILIA; HERRERA, M; MAZZITELLI, I.; TURK, GABRIELA; GUEVARA, D; VIEIGAS, M; QUIROGA, FLORENCIA; LAUFER, NATALIA; CUESTAS, MC

Persistent SARS-Cov-2 Infection in an Immunocompromised Host. Role of the Cellular Immune Response

Austin Journal of Clinical Immunology; Lugar: Austin; Año: 2023 vol. 9 p. 1 - 4

BOWEN, JOHN E.; PARK, YOUNG-JUN; STEWART, CAMERON; BROWN, JACK T.; SHARKEY, WILLIAM K.; WALLS, ALEXANDRA C.; JOSHI, ANSHU; SPROUSE, KAITLIN R.; MCCALLUM, MATTHEW; TORTORICI, M. ALEJANDRA; FRANKO, NICHOLAS M.; LOGUE, JENNIFER K.; MAZZITELLI, IGNACIO G.; NGUYEN, ANNALEE W.; SILVA, RUI P.; HUANG, YIMIN; LOW, JUN SIONG; JERAK, JOSIPA; TILES, SASHA W.; AHMED, KUMAIL; SHARIQ, ASEFA; DAN, JENNIFER M.; ZHANG, ZELI; WEISKOPF, DANIELA; SETTE, ALESSANDRO; SNELL, GYORGY; POSAVAD, CHRISTINE M.; IQBAL, NAJEEHA TALAT; GEFFNER, JORGE; BANDERA, ALESSANDRA; GORI, ANDREA; SALLUSTO, FEDERICA; MAYNARD, JENNIFER A.; CROTTY, SHANE; VAN VOORHIS, WESLEY C.; SIMMERLING, CARLOS; GRIFANTINI, RENATA; CHU, HELEN Y.; CORTI, DAVIDE; VEESLER, DAVID

SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines

Science Immunology; Año: 2022 vol. 7

MAZZITELLI, IGNACIO; BLEICHMAR, LUCÍA; MELUCCI, CLAUDIA; GERBER, PEHUÉN PEREYRA; TOSCANINI, AGUSTINA; CUESTAS, MARÍA LUJÁN; DIAZ, FERNANDO ERRA; GEFFNER, JORGE

High Salt Induces a Delayed Activation of Human Neutrophils

Frontiers in Immunology; Año: 2022 vol. 13

KUNDRO, M.A.; LOSSO, M.H.; MACCHIA, A.; PASTOR, I.; ALONSO SERENA, M.; GESTOSO, C.; MORENO MACÍAS, L.; CRUPI, F.; ACOSTA, M.C.; IVALO, S.; GHIOLDI, M.; BOUZAS, M.B.; MAMMANA, L.; ZAPIOLA, I.; MAZZITELLI, I.; VARESE, A.; GEFFNER, J.; BISCAYART, C.; ANGELERI, P.; LOPEZ, E.; GENTILE, A.; FERRANTE, D.; DE QUIROS, F. GONZALEZ B.

Safety and immunogenicity of heterologous COVID-19 vaccine regimens to deal with product shortage: A randomised clinical trial in an elderly population

Public Health in Practice; Año: 2022 vol. 4

SEERY, VANESA; RAIDEN, SILVINA; RUSSO, CONSTANZA; BORDA, MAURICIO; HERRERA, LARGIÓN; URANGA, MACARENA; VARESE, AUGUSTO; MARCÓ DEL PONT, MARÍA; CHIRINO, CARINA; ERRAMUSPE, CONSTANZA; ÁLVAREZ, LAURA SILVANA; LENOIR, MELISA; MORALES, LAURA DANIELA; DAVENPORT, CAROLINA; ALARCÓN FLORES, ALEXSA; HUESPE AUCHTER, SOLEDAD; RUIZ, YANINA; MONSALVO, LILIANA; SASTOQUE, LAURA; GAVAZZI, MAGALÍ; MAZZITELLI, IGNACIO; DI DIEGO, FACUNDO; LONGUEIRA, YESICA; MAZZITELLI, BIANCA; SANANEZ, INÉS; DE CARLI, NORBERTO; BIGLIONE, MIRNA MARCELA; GÓMEZ PENEDO, JUAN MARTÍN; CEBALLOS, ANA; LAUFER, NATALIA; FERRERO, FERNANDO; GEFFNER, JORGE; ARRUVITO, LOURDES

Antibody response against SARS-CoV-2 variants of concern in children infected with pre-Omicron variants: An observational cohort study

eBioMedicine; Año: 2022 vol. 83

PASCUALE, CARLA A.; VARESE, AUGUSTO; OJEDA, DIEGO S.; PASINOVICH, MARINA E.; LOPEZ, LAURA; ROSSI, ANDRES H.; RODRIGUEZ, PAMELA E.; MIGLIETTA, ESTEBAN A.; MAZZITELLI, IGNACIO; DI DIEGO GARCIA, FACUNDO; SANCHEZ, LAUTARO; ROUCO, SANTIAGO OVIEDO; GONZALEZ LOPEZ LEDESMA, MARÍA MORA; ZURANO, JUAN PABLO; MAZZITELLI, BIANCA; SCRUZZI, GRACIELA; BARBERO, PAULA; CARDOZO, DIEGO; GALLEGO, SANDRA; BORDA, MARIEL; DIAZ, MIGUEL; RIDAO, FRANCISCO; ROSALES, ANGELA BRIGIDO; BHON, JORGE; TALIA, JUAN M.; DIANGELO, MARÍA E.; LACAZE, MARÍA A.; AIME, BALANZINO; GUTIERREZ, SEBASTIAN ISAAC; ERCOLE, REGINA; TORO, ROSANA; TAU, LORENA; DELAPLACE, LAURA; COMPAGNUCCI, MALENA FERREYRA; SARTORI, CELESTE; DESIMONE, ISABEL; ECHEGOYEN, CECILIA; VELAZQUEZ, PILAR; TESTA, CLARISA; HOZBOR, DANIELA; DOCENA, GUILLERMO; LAINO, CARLOS H.; KREPLAK, NICOLAS; PIFANO, MARINA; BARBAS, GABRIELA; REARTE, ANALÍA; VIZZOTTI, CARLA; CASTELLI, JUAN M.; GEFFNER, JORGE; GAMARNIK, ANDREA V.

Immunogenicity and reactogenicity of heterologous immunization against SARS CoV-2 using Sputnik V, ChAdOx1-S, BBIBP-CorV, Ad5-nCoV, and mRNA-1273

Cell Reports Medicine; Año: 2022 vol. 3

BOWEN, JOHN E.; ADDETIA, AMIN; DANG, HA V.; STEWART, CAMERON; BROWN, JACK T.; SHARKEY, WILLIAM K.; SPROUSE, KAITLIN R.; WALLS, ALEXANDRA C.; MAZZITELLI, IGNACIO G.; LOGUE, JENNIFER K.; FRANKO, NICHOLAS M.; CZUDNOCHOWSKI, NADINE; POWELL, ABIGAIL E.; DELLOTA, EXEQUIEL; AHMED, KUMAIL; ANSARI, ASEFA SHARIQ; CAMERONI, ELISABETTA; GORI, ANDREA; BANDERA, ALESSANDRA; POSAVAD, CHRISTINE M.; DAN, JENNIFER M.; ZHANG, ZELI; WEISKOPF, DANIELA; SETTE, ALESSANDRO; CROTTY, SHANE; IQBAL, NAJEEHA TALAT; CORTI, DAVIDE; GEFFNER, JORGE; SNELL, GYORGY; GRIFANTINI, RENATA; CHU, HELEN Y.; VEESLER, DAVID

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

SCIENCE; Año: 2022 vol. 377 p. 890 - 894

MACCHIA, ALEJANDRO; FERRANTE, DANIEL; BOUZAS, MARÍA BELÉN; ANGELERI, PATRICIA; BISCAYART, CRISTIÁN; GEFFNER, JORGE; MAMMANA, LILIA; ZAPIOLA, INÉS; LÓPEZ, EDUARDO LUIS; GENTILE, ANGELA; VARESE, AUGUSTO; MAZZITELLI, IGNACIO; GARCÍA, FACUNDO DI DIEGO; SHARFF, DEBORAH; LUCCONI, VERÓNICA; SUJANSKY, PAULA; MARIANI, JAVIER; DE QUIRÓS, FERNÁN GONZÁLEZ BERNALDO

Immunogenicity induced by the use of alternative vaccine platforms to deal with vaccine shortages in a low- to middle-income country: Results of two randomized clinical trials

The Lancet Regional Health - Americas; Año: 2022 vol. 9

VIACAVA, MYRIAM BELÉN GONZÁLEZ; VARESE, AUGUSTO; MAZZITELLI, IGNACIO; LANARI, LAURA; ÁVILA, LUCÍA; VAMPA, MARÍA JULIA GARCÍA; GEFFNER, JORGE; CASCONE, OSVALDO; DOKMETJIAN, JOSÉ CHRISTIAN; DE ROODT, ADOLFO RAFAEL; FINGERMANN, MATÍAS

Immune Maturation Effects on Viral Neutralization and Avidity of Hyperimmunized Equine Anti-SARS-CoV-2 Sera

Antibodies; Año: 2022 vol. 11

PALETTA, ANA; DI DIEGO GARCÍA, FACUNDO; VARESE, AUGUSTO; ERRA DIAZ, FERNANDO; GARCÍA, JULIÁN; CISNEROS, JUAN CARLOS; LUDUEÑA, GUILLERMINA; MAZZITELLI, IGNACIO; PISAREVSKY, ANDREA; CABRERIZO, GONZALO; LÓPEZ MALIZIA, ÁLVARO; RODRIGUEZ, ALEJANDRA G.; LISTA, NICOLÁS; LONGUEIRA, YESICA; SABATTÉ, JUAN; GEFFNER, JORGE; REMES LENICOV, FEDERICO; CEBALLOS, ANA

Platelets modulate CD4+ T-cell function in COVID-19 through a PD-L1 dependent mechanism

BRITISH JOURNAL OF HAEMATOLOGY; Año: 2022 vol. 197 p. 283 - 292

GONZALEZ LOPEZ LEDESMA, MARÍA M.; SANCHEZ, LAUTARO; OJEDA, DIEGO S.; ROUCO, SANTIAGO OVIEDO; ROSSI, ANDRÉS H.; VARESE, AUGUSTO; MAZZITELLI, IGNACIO; PASCUALE, CARLA A.; MIGLIETTA, ESTEBAN A.; RODRÍGUEZ, PAMELA E.; PALLARÉS, HORACIO M.; COSTA NAVARRO, GUADALUPE S.; CARAMELO, JULIO J.; ROTHLAUF, PAUL W.; LIU, ZHUOMING; BLOYET, LOUIS-MARIE; PONTELLI, MARJORIE CORNEJO; RASETTO, NATALI B.; WENKER, SHIRLEY D.; RAMIS, LILA Y.; BIALER, MAGALÍ G.; DE LEONE, MARÍA JOSE; ESTEBAN HERNANDO, C.; BIANCHIMANO, LUCIANA; RÍOS, ANTONELLA S.; CIENFUEGOS, MARÍA SOLEDAD TREFFINGER; RODRIGUEZ GARCÍA, DIANA R.; LONGUEIRA, YESICA; LAUFER, NATALIA; ALVAREZ, DIEGO; CEBALLOS, ANA; OCHOA, VALERIA; MONZANI, CECILIA; TURK, GARIELA; SALVATORI, MELINA; CARRADORI, JORGE; PROST, KATHERINE; RIMA, ALEJANDRA; VARELA, CLAUDIA; ERCOLE, REGINA; TORO, ROSANA I.; GUTIERREZ, SEBASTIAN; ZUBIETA, MARTÍN; ACUÑA, DOLORES; NABAES JODAR, MERCEDES S.; TORRES, CAROLINA; MOJSIEJCZUK, LAURA; VIEGAS, MARIANA; VELAZQUEZ, PILAR; TESTA, CLARISA; KREPLAK, NICOLAS; YA

Longitudinal Study after Sputnik V Vaccination Shows Durable SARS-CoV-2 Neutralizing Antibodies and Reduced Viral Variant Escape to Neutralization over Time

mBio; Año: 2022 vol. 13

CAMERONI, ELISABETTA; BOWEN, JOHN E.; ROSEN, LAURA E.; SALIBA, CHRISTIAN; ZEPEDA, SAMANTHA K.; CULAP, KATJA; PINTO, DORA; VANBLARGAN, LAURA A.; DE MARCO, ANNA; DI IULIO, JULIA; ZATTA, FABRIZIA; KAISER, HANNAH; NOACK, JULIA; FARHAT, NISAR; CZUDNOCHOWSKI, NADINE; HAVENAR-DAUGHTON, COLIN; SPROUSE, KAITLIN R.; DILLEN, JOSH R.; POWELL, ABIGAIL E.; CHEN, ALEX; MAHER, CYRUS; YIN, LI; SUN, DAVID; SORIAGA, LEAH; BASSI, JESSICA; SILACCI-FREGNI, CHIARA; GUSTAFSSON, CLAES; FRANKO, NICHOLAS M.; LOGUE, JENNI; IQBAL, NAJEEHA TALAT; MAZZITELLI, IGNACIO; GEFFNER, JORGE; GRIFANTINI, RENATA; CHU, HELEN; GORI, ANDREA; RIVA, AGOSTINO; GIANNINI, OLIVIER; CESCHI, ALESSANDRO; FERRARI, PAOLO; CIPPÀ, PIETRO E.; FRANZETTI-PELLANDA, ALESSANDRA; GARZONI, CHRISTIAN; HALFMANN, PETER J.; KAWAOKA, YOSHIHIRO; HEBNER, CHRISTY; PURCELL, LISA A.; PICCOLI, LUCA; PIZZUTO, MATTEO SAMUELE; WALLS, ALEXANDRA C.; DIAMOND, MICHAEL S.; TELENTI, AMALIO; VIRGIN, HERBERT W.; LANZAVECCHIA, ANTONIO; SNELL, GYORGY; VEESLER, DAVID; CORTI, DAVIDE

Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

NATURE; Año: 2022 vol. 602 p. 664 - 670

OCHOA, VALERIA; DÍAZ, FERNANDO ERRA; RAMIREZ, EZEQUIEL; FENTINI, MARÍA CLARA; CAROBENE, MAURICIO; GEFFNER, JORGE; ARRUVITO, LOURDES; REMES LENICOV, FEDERICO; ADAMCZYK, ALAN; AZZOLINA, SABRINA; BAQUERO, LUCÍA; BENENCIO, PAULA; BERINI, CAROLINA; BIGLIONE, MIRNA; BLEICHMAR, LUCÍA; CABRERIZO, GONZALO; CASSIME, SILVIA; CASSIME, RICARDO; CEBALLOS, ANA; CEVALLOS, CINTIA; CZERNIKIER, ALEJANDRO; DELPINO, VICTORIA; DI DIEGO GARCÍA, FACUNDO; DUCASA, NICOLÁS; ELIZALDE, MERCEDES; FLICHMAN, DIEGO; GATTI, RAMIRO; GHIGLIONE, YANINA; GIANNONE, DENISE; GÓMEZ, CLAUDIO; GONZALEZ POLO, VIRGINIA; LAUFER, NATALIA; LEICAJ, LUZ; LONGUEIRA, YESICA; LOPEZ MALIZZIA, ALVARO; MAZZITELLI, IGNACIO; MELUCCI GANZARAIN, CLAUDIA; MONTESANO, FERNANDO; MORANDO, NICOLÁS; OSTROWSKI, MATÍAS; PAMPURO, SANDRA; PALETTA, ANA; PANDO, MARÍA; PENAS, FEDERICO; PCROSSED D SIGN©REZ, PAULA; PICCARDO, CLAUDIO; PIERALISI, AZUL; PIPPO, MÓNICA; POLO, LAURA; QUIROGA, FLORENCIA; SABATTCROSSED D SIGN©, JUAN; SALVATORI, MELINA; SANANES, INCROSSED D SIGN©S; SEERY, VANE

Infants Younger Than 6 Months Infected With SARS-CoV-2 Show the Highest Respiratory Viral Loads

JOURNAL OF INFECTIOUS DISEASES; Año: 2022 vol. 225 p. 392 - 395

CORIA, LORENA M.; SAPOSNIK, LUCAS M.; PUEBLAS CASTRO, CELESTE; CASTRO, ELIANA F.; BRUNO, LAURA A.; STONE, WILLIAM B.; PÉREZ, PAULA S.; DARRIBA, MARIA LAURA; CHEMES, LUCIA B.; ALCAIN, JULIETA; MAZZITELLI, IGNACIO; VARESE, AUGUSTO; SALVATORI, MELINA; AUGUSTE, ALBERT J.; ÁLVAREZ, DIEGO E.; PASQUEVICH, KARINA A.; CASSATARO, JULIANA

A Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice

Frontiers in Immunology; Año: 2022 vol. 13

MAZZITELLI, IGNACIO; BLEICHMAR, LUCIA; LUDUEÑA, MARÍA GUILLERMINA; PISAREVSKY, ANDREA; LABATO, MARIANA; CHIARADIA, VERÓNICA; FINOCCHIETO, PAOLA; PAULIN, FRANCISCO; HORMANSTORFER, MACARENA; BARETTO, MARÍA CONSTANZA; ADANZA, SANTIAGO PIOMBI; PARODI, MARÍA NOEL; RAGUSA, MARTÍN; MELUCCI, CLAUDIA; DÍAZ, FERNANDO ERRA; PALETTA, ANA; DI DIEGO, FACUNDO; CEBALLOS, ANA; GEFFNER, JORGE

Immunoglobulin G Immune Complexes May Contribute to Neutrophil Activation in the Course of Severe Coronavirus Disease 2019

JOURNAL OF INFECTIOUS DISEASES; Año: 2021 vol. 224 p. 575 - 585

ROSSI, ANDRES H.; OJEDA, DIEGO S.; VARESE, AUGUSTO; SANCHEZ, LAUTARO; GONZALEZ LOPEZ LEDESMA, MARIA M.; MAZZITELLI, IGNACIO; ALVAREZ JULIÁ, ANABEL; OVIEDO ROUCO, SANTIAGO; PALLARÉS, HORACIO M.; COSTA NAVARRO, GUADALUPE S.; RASETTO, NATALI B.; GARCIA, CORINA I.; WENKER, SHIRLEY D.; RAMIS, LILA Y.; BIALER, MAGALÍ G.; DE LEONE, MARIA JOSE; HERNANDO, C. ESTEBAN; SOSA, SANTIAGO; BIANCHIMANO, LUCIANA; RIOS, ANTONELLA S.; TREFFINGER CIENFUEGOS, MARIA SOLEDAD; CARAMELO, JULIO J.; LONGUEIRA, YESICA; LAUFER, NATALIA; ALVAREZ, DIEGO E.; CARRADORI, JORGE; PEDROZZA, DARIANA; RIMA, ALEJANDRA; ECHEGOYEN, CECILIA; ERCOLE, REGINA; GELPI, PAULA; MARCHETTI, SUSANA; ZUBIETA, MARTÍN; DOCENA, GUILLERMO; KREPLAK, NICOLAS; YANOVSKY, MARCELO; GEFFNER, JORGE; PIFANO, MARINA; GAMARNIK, ANDREA V.

Sputnik V vaccine elicits seroconversion and neutralizing capacity to SARS-CoV-2 after a single dose

Cell Reports Medicine; Año: 2021 vol. 2

ERRA DÍAZ, FERNANDO; OCHOA, VALERIA; MERLOTTI, ANTONELA; DANTAS, EZEQUIEL; MAZZITELLI, IGNACIO; GONZALEZ POLO, VIRGINIA; SABATTÉ, JUAN; AMIGORENA, SEBASTIÁN; SEGURA, ELODIE; GEFFNER, JORGE

Extracellular Acidosis and mTOR Inhibition Drive the Differentiation of Human Monocyte-Derived Dendritic Cells

Cell Reports; Año: 2020 vol. 31