Yerba mate (Ilex paraguariensis) favors survival and growth of dopaminergic neurons in culture

BERNARDI, ALEJANDRA; BALLESTERO, PEDRO; SCHENK, MARCELA; FERRARIO, MARIANA; GÓMEZ, GIMENA; RIVERO, ROY; AVALE, ELENA; TARAVINI, IRENE; GERSHANIK, OSCAR; GUERRERO, SANDRA; FERRARIO, JUAN E.

MOVEMENT DISORDERS

WILEY-LISS, DIV JOHN WILEY & SONS INC

Lugar: New York; Año: 2019

0885-3185

The infusion from Ilex paraguariensis (popularly known asYerba mate [YM]) produces the very popular South Americanbeverage called mate (pronounced as ?mateI? or maté), andits intake has been inversely associated with the developmentof Parkinson?s disease (PD) in a large population study inArgentina.1 Given that the influence of diet on health (and disease)of the brain is currently a major issue, and the improvementin the tools to detect the signs and symptoms of PD in itsprodromal period,2 it becomes highly relevant to identify andvalidate potential neuroprotective dietary products that maypositively impact on the progression of the disease.We tested whether YM could be protective to d