GALCERAN, FACUNDO; DIGIROLAMO, FABIO A.; RENGIFO, MARCOS; REIGADA, CHANTAL; SAYE, MELISA; MACIEL, BELEN J.; ESTECHO, IVANA G.; ERRASTI, ANDREA E.; PEREIRA, CLAUDIO A.; MIRANDA, MARIANA R.

Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas’ disease

BIOCHEMICAL PHARMACOLOGY; Año: 2023

RIAL, MARCELA S; REIGADA, CHANTAL; PRADO, NILDA; BUA, JACQUELINE; ESTEVA, MÓNICA; PEREIRA, CLAUDIO A; FICHERA, LAURA E

Effectiveness of the repurposed drug isotretinoin in an experimental murine model of Chagas disease

ACTA TROPICA; Año: 2023 vol. 242

REIGADA C; DI GIROLAMO F; GALCERAN F; MARTÍNEZ SAYÉ M; CARRILLO C; TORRES P; CAMMARATA A; GLISONI R; LABADIÉ G; MIRANDA MR; PEREIRA CA

Trypanocidal activity of liposomal isotretinoin and loratadine formulations

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY; Año: 2023 vol. 91

MIRANDA, MARIANA R.; SAYÉ, MELISA; REIGADA, CHANTAL; GALCERAN, FACUNDO; RENGIFO, MARCOS; MACIEL, BELEN J.; DIGIROLAMO, FABIO A.; PEREIRA, CLAUDIO A.

Revisiting trypanosomatid nucleoside diphosphate kinases

Memorias do Instituto Oswaldo Cruz; Año: 2022 vol. 116

VALERA-VERA, EDWARD; REIGADA, CHANTAL; SAYÉ, MELISA; DIGIROLAMO, FABIO A.; GALCERAN, FACUNDO; MIRANDA, MARIANA R.; PEREIRA, CLAUDIO A.

Trypanocidal activity of the anthocyanidin delphinidin, a non-competitive inhibitor of arginine kinase

NATURAL PRODUCT RESEARCH; Año: 2021

CHANTAL REIGADA; MELISA SAYÉ; FABIO DI GIROLAMO; EDWARD A. VALERA VERA; CLAUDIO A. PEREIRA; MARIANA R. MIRANDA

Role of Trypanosoma cruzi nucleoside diphosphate kinase 1 in DNA-damage responses

MEMóRIAS DO INSTITUTO OSWALDO CRUZ.; Lugar: Rio de Janeiro; Año: 2020

MELISA SAYÉ; LUCRECIA GAUNA; EDWARD A. VALERA VERA; CHANTAL REIGADA; MARIANA R. MIRANDA; CLAUDIO A. PEREIRA

Crystal violet structural analogues identified by in silico drug repositioning present anti Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069

PLOS NEGLECTED TROPICAL DISEASES; Lugar: San Francisco; Año: 2020

PEREIRA, CLAUDIO A.; SAYÉ, MELISA; REIGADA, CHANTAL; SILBER, ARIEL M.; LABADIE, GUILLERMO R.; MIRANDA, MARIANA R.; VALERA-VERA, EDWARD

Computational approaches for drug discovery against trypanosomatid caused diseases

PARASITOLOGY; Año: 2020 p. 1 - 68

EDWARD A. VALERA VERA; MELISA SAYÉ; CHANTAL REIGADA; MARIANA R. MIRANDA; CLAUDIO A. PEREIRA

In silico repositioning of etidronate as a potential inhibitor of the Trypanosoma cruzi enolase

JOURNAL OF MOLECULAR GRAPHICS & MODELLING.; Año: 2020

VALERA-VERA, EDWARD A; REIGADA, CHANTAL; SAYÉ, MELISA; DIGIROLAMO, FABIO A; GALCERAN, FACUNDO; MIRANDA, MARIANA R; PEREIRA, CLAUDIO A

Effect of capsaicin on the protozoan parasite Trypanosoma cruzi

FEMS MICROBIOLOGY LETTERS; Año: 2020

CHANTAL REIGADA; MELISA SAYÉ; OTTO PHANSTIEL; EDWARD A. VALERA VERA; MARIANA R. MIRANDA; CLAUDIO A. PEREIRA

Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing

Frontiers in Medicine; Lugar: Lausanne; Año: 2019

CHANTAL REIGADA; MELISA SAYÉ; EDWARD A. VALERA VERA; MARIANA R. MIRANDA; CLAUDIO A. PEREIRA

Repurposing of terconazole as an anti Trypanosoma cruzi agent

HELIYON; Lugar: Londres; Año: 2019 vol. 5

MELISA SAYÉ; CHANTAL REIGADA; LUCRECIA GAUNA; EDWARD A. VALERA VERA; CLAUDIO A. PEREIRA; MARIANA R. MIRANDA

Amino acid and polyamine membrane transporters in Trypanosoma cruzi: biological function and evaluation as drug targets

CURRENT MEDICINAL CHEMISTRY.; Lugar: Oak Park; Año: 2019

REIGADA, CHANTAL; PHANSTIEL, OTTO; MIRANDA, MARIANA R.; PEREIRA, CLAUDIO A.

Targeting polyamine transport in Trypanosoma cruzi

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Lugar: Paris; Año: 2018 vol. 147 p. 1 - 6

MARÍA DE LOS MILAGROS CÁMARA; LEÓN BOUVIER; CHANTAL REIGADA; FABIO A. DIGIROLAMO; MELISA SAYÉ; CLAUDIO A. PEREIRA

A novel stage-specific glycosomal nucleoside diphosphate kinase from Trypanosoma cruzi.

FOLIA PARASITOLOGICA; Año: 2017

REIGADA C; VALERA VERA EA; SAYÉ M; ERRASTI AE; AVILA CC; MIRANDA MR; PEREIRA CA

Trypanocidal effect of isotretinoin through the inhibition of polyamine and amino acid transporters in Trypanosoma cruzi

PLOS NEGLECTED TROPICAL DISEASES; Lugar: San Francisco; Año: 2017

SAYÉ, MELISA; FARGNOLI, LUCÍA; REIGADA, CHANTAL; LABADIE, GUILLERMO R.; PEREIRA, CLAUDIO A.

Evaluation of proline analogs as trypanocidal agents through the inhibition of a Trypanosoma cruzi proline transporter

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS; Año: 2017

SEGUEL V; CASTRO L; REIGADA C; CORTES L; DÍAZ MV; MIRANDA MR; PEREIRA CA; LAPIER M; CAMPOS-ESTRADA C; MORELLO A; KEMMERLING U; MAYA JD; LÓPEZ-MUÑOZ R

Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about the polyamine transport as an anti-Trypanosoma cruzi target.

EXPERIMENTAL PARASITOLOGY; Lugar: Amsterdam; Año: 2016 p. 23 - 32

MELISA MARTINEZ SAYÉ; MARIANA R. MIRANDA; CHANTAL REIGADA; CLAUDIO A. PEREIRA

Trypanosoma cruzi Proline Transport Presents a Cell Density-dependent Regulation

JOURNAL OF EUKARYOTIC MICROBIOLOGY; Año: 2016

CHANTAL REIGADA; MELISA MARTINEZ SAYÉ; EDWARD A. VALERA VERA; DARÍO BALCAZAR; LAURA FRACCAROLI; CAROLINA CARRILLO; MARIANA R. MIRANDA; CLAUDIO A. PEREIRA

Trypanosoma cruzi polyamine transporter: its role on parasite growth and survival under stress conditions.

JOURNAL OF MEMBRANE BIOLOGY; Lugar: Berlin; Año: 2016

EDWARD A. VALERA VERA; MELISA MARTINEZ SAYÉ; CHANTAL REIGADA; FLAVIA S. DAMASCENO; ARIEL M. SILBER ; MARIANA R. MIRANDA; CLAUDIO A. PEREIRA

Resveratrol inhibits Trypanosoma cruzi arginine kinase and exerts a trypanocidal activity.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES; Lugar: Amsterdam; Año: 2016

MARIANA R. MIRANDA; MELISA MARTINEZ SAYÉ; CHANTAL REIGADA; CAROLINA CARRILLO; CLAUDIO A. PEREIRA

Phytomonas: a non-pathogenic trypanosomatid model for functional expression of proteins

PROTEIN EXPRESSION AND PURIFICATION; Año: 2015

MARÍA V. DÍAZ; MARIANA R. MIRANDA; CAROLINA CAMPOS-ESTRADA; CHANTAL REIGADA; JUAN D. MAYA; CLAUDIO A. PEREIRA ; RODRIGO LÓPEZ-MUÑOZ

Pentamidine exerts in vitro and in vivo anti Trypanosoma cruzi activity and inhibits the polyamine transport in Trypanosoma cruzi.

ACTA TROPICA; Lugar: Amsterdam; Año: 2014 vol. 134 p. 1 - 9

CLAUDIO A. PEREIRA; CHANTAL REIGADA; SAYÉ M; FABIO A. DI GIROLAMO ; MARIANA R. MIRANDA

Cytosolic Trypanosoma cruzi nucleoside diphosphate kinase generates large granules that depend on its quaternary structure.

EXPERIMENTAL PARASITOLOGY; Lugar: Amsterdam; Año: 2014 vol. 142 p. 43 - 50

MARÍA DE LOS MILAGROS CÁMARA; LEÓN A. BOUVIER; MARIANA R. MIRANDA; CHANTAL REIGADA; CLAUDIO A. PEREIRA

Laboratory techniques to obtain different forms of Trypanosoma cruzi: applications to wild-type and genetically modified parasites

FOLIA PARASITOLOGICA; Año: 2013 vol. 60 p. 406 - 410