Sensing carbohydrates in the near-infrared region with a fluorescent boronolectin

CECILIA SAMANIEGO LOPEZ; MARÍA LAURA UHRIG; MARÍA AMPARA LAGO HUVELLE; FEDERICO COLUCCIO LESKOW ; CARLA CECILIA SPAGNUOLO

Heidelberg

Conferencia; 1st Labeling and nanoscopy Conference; 2014

German Cancer Research Center

In the context of a main project to develop versatile near-infrared fluorescent probes for relevant biologic analytes we describe the synthesis and sensing performance of a boronolectin derived from a tricarbocyanine dye. Boronic acids have been widely used for saccharide recognition through the formation of a reversible complex with diols. The dynamic covalent nature of this interaction has inspired research on different kinds of molecular and supramolecular systems with a wide variety of applications.