VERÓNICA ELENA MANZANO; LUCAS DADA; MARÍA LAURA UHRIG; OSCAR VARELA

Synthesis of sugar enones and their use as powerful synthetic precursors of thiodisaccharides

CARBOHYDRATE RESEARCH; Lugar: Amsterdam; Año: 2023

CANO, MARÍA EMILIA; JARA, WALTER EMILIANO; CAGNONI, ALEJANDRO J.; BRIZZIO, EMMANUEL; STRUMIA, MIRIAM C.; REPETTO, EVANGELINA; UHRIG, MARÍA LAURA

The disulfide bond as a key motif for the construction of multivalent glycoclusters

NEW JOURNAL OF CHEMISTRY; Año: 2022 vol. 46 p. 17682 - 17695

MORRONE-POZZUTO, PABLO; UHRIG, MARÍA LAURA; AGUSTI, ROSALIA

Synthesis of Oligosaccharides Containing the S-Gal p(α1 → 3)Gal p Unit, Glycomimetic of the Epitope Recognized by Lytic Antibodies

JOURNAL OF ORGANIC CHEMISTRY; Año: 2022 vol. 2022

MARÍA LAURA UHRIG; MORA FLORES, ERWIN W.; ALBERTO POSTIGO

Approaches to the Synthesis of Perfluoroalkyl-Modified Carbohydrates and Derivatives: thiosugars, iminosugars, and tetrahydro(thio)pyrans

CHEMISTRY-A EUROPEAN JOURNAL; Lugar: Weinheim; Año: 2021 p. 7813 - 7825

CRISTÓFALO, ALEJANDRO E.; NIETO, PEDRO M.; THÉPAUT, MICHEL; FIESCHI, FRANCK; DI CHENNA, PABLO H.; UHRIG, MARÍA LAURA

Synthesis, self-assembly and Langerin recognition studies of a resorcinarene-based glycocluster exposing a hyaluronic acid thiodisaccharide mimetic

ORGANIC & BIOMOLECULAR CHEMISTRY; Lugar: CAMBRIDGE; Año: 2021 vol. 19 p. 6455 - 6467

CRISTÓFALO, ALEJANDRO E.; CANO, MARÍA EMILIA; UHRIG, MARÍA LAURA

Synthesis of Thiodisaccharides Bearing N-Acetylhexosamine Residues: Challenges, Achievements and Perspectives

CHEMICAL RECORD; Año: 2021 vol. 2021 p. 1 - 30

CRISTÓFALO, ALEJANDRO E.; UHRIG, MARÍA LAURA

Synthetic Studies on the Incorporation of N-Acetylallosamine in Hyaluronic Acid-Inspired Thiodisaccharides

MOLECULES; Año: 2021 vol. 26 p. 180 - 192

CRISTÓFALO, ALEJANDRO E.; CAGNONI, ALEJANDRO J.; UHRIG, MARÍA LAURA

Synthesis of N -acetylglucosamine and N -acetylallosamine resorcinarene-based multivalent β-thio-glycoclusters: unexpected affinity of N -acetylallosamine ligands towards Wheat Germ Agglutinin

ORGANIC & BIOMOLECULAR CHEMISTRY; Año: 2020 vol. 18 p. 6853 - 6865

LENCI KARINA VÁZQUEZ-JIMÉNEZ; ALMA DELIA PAZ-GONZÁLEZ; ALFREDO JUÁREZ-SALDIVAR; MARÍA LAURA UHRIG; ROSALÍA AGUSTÍ; ALICIA REYES-ARELLANO; BENJAMÍN NOGUEDA-TORRES; GILDARDO RIVERA

Structure-Based Virtual Screening of New Benzoic Acid Derivatives as Trypanosoma cruzi Trans-sialidase Inhibitors

MEDICINAL CHEMISTRY; Lugar: Oak Park; Año: 2020

CRISTÓFALO, ALEJANDRO EZEQUIEL; NIETO, PEDRO M.; UHRIG, MARÍA LAURA

Synthesis of (1-3) Thiodisaccharides of GlcNAc and the Serendipitous Formation of 2,3-Dideoxy-(1-2)-thiodisaccharides through a Vinyl Azide Intermediate

JOURNAL OF ORGANIC CHEMISTRY; Año: 2020 vol. 85 p. 306 - 317

MORA FLORES, ERWIN W.; UHRIG, MARÍA LAURA; POSTIGO, AL

Photocatalyzed reductive fluoroalkylation of 2-acetoxyglycals towards the stereoselective synthesis of α-1-fluoroalkyl- C -glycosyl derivatives

ORGANIC & BIOMOLECULAR CHEMISTRY; Año: 2020 vol. 18 p. 8724 - 8734

ALEJANDRO J. CAGNONI; EMILIANO D. PRIMO; SEBASTIÁN KLINKE; MARÍA E. CANO; WALTER GIORDANO; KARINA V. MARIÑO; JOSÉ KOVENSKY; FERNANDO A. GOLDBAUM; MARÍA L. UHRIG; LISANDRO H. OTERO

Crystal structures of peanut lectin in the presence of synthetic beta-N- and beta-S-galactosides disclose evidences for the recognition of different glycomimetic ligands

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY; Año: 2020 vol. 76 p. 1080 - 1091

MORRONE-POZZUTO, PABLO; UHRIG, MARIA LAURA; AGUSTI, ROSALIA

Trypanosoma cruzi trans-sialidase alternative substrates: Study of the effect of substitution in C-6 in benzyl β-lactoside

CARBOHYDRATE RESEARCH; Año: 2019 vol. 478 p. 33 - 45

UHRIG, MARÍA LAURA; LANTAÑO, BEATRIZ; POSTIGO, AL

Synthetic strategies for fluorination of carbohydrates

ORGANIC & BIOMOLECULAR CHEMISTRY; Año: 2019

MONTENEGRO, HUGO O.; DI CHENNA, PABLO H.; SPAGNUOLO, CARLA C.; UHRIG, MARÍA LAURA

Multivalent assembly of a pyrene functionalized thio-N-acetylglucosamine: Synthesis, spectroscopic and WGA binding studies

CARBOHYDRATE RESEARCH; Año: 2019 vol. 479 p. 6 - 12

SAMANIEGO LOPEZ, CECILIA; MARTÍNEZ, JIMENA HEBE; UHRIG, MARÍA LAURA; COLUCCIO LESKOW, FEDERICO; SPAGNUOLO, CARLA CECILIA

A Highly Sensitive Fluorogenic Probe for Imaging Glycoproteins and Mucine Activity in Live Cells in the Near-Infrared Region

CHEMISTRY-A EUROPEAN JOURNAL; Año: 2018 vol. 24 p. 6344 - 6348

KASHIF, MUHAMMAD; CHACON-VARGAS, KARLA FABIOLA; LOPEZ-CEDILLO, JULIO CESAR; NOGUEDA-TORRES, BENJAMÍN; PAZ-GONZALEZ, ALMA D.; RAMÍREZ-MORENO, ESTHER; AGUSTI, ROSALIA; UHRIG, MARIA LAURA; REYES-ARELLANO, ALICIA; PERALTA-CRUZ, JAVIER; ASHFAQ, MUHAMMAD; RIVERA, GILDARDO

Synthesis, molecular docking and biological evaluation of novel phthaloyl derivatives of 3-amino-3-aryl propionic acids as inhibitors of Trypanosoma cruzi trans-sialidase

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Año: 2018 vol. 156 p. 252 - 268

LARA-RAMIREZ, EDGAR E.; LÓPEZ-CEDILLO, JULIO CESAR; NOGUEDA-TORRES, BENJAMIN; KASHIF, MUHAMMAD; GARCIA-PEREZ, CARLOS; BOCANEGRA-GARCIA, VIRGILIO; AGUSTI, ROSALÍA; UHRIG, MARÍA LAURA; RIVERA, GILDARDO

An in vitro and in vivo evaluation of new potential trans-sialidase inhibitors of Trypanosoma cruzi predicted by a computational drug repositioning method

EUROPEAN JOURNAL OF MEDICAL CHEMISTRY; Año: 2017 vol. 132 p. 249 - 261

MARÍA EMILIA CANO; PABLO HÉCTOR DI CHENNA; DAVID LESUR; ALEJANDRO WOLOSIUK; JOSÉ KOVENSKY; MARÍA LAURA UHRIG

Chirality inversion, supramolecular hydrogelation and lectin binding of two thiolactose amphiphiles constructed on a di-lauroyl-L-tartaric acid scaffold

NEW JOURNAL OF CHEMISTRY; Lugar: CAMBRIDGE; Año: 2017 vol. 41 p. 14754 - 14765

MARÍA EMILIA CANO; OSCAR VARELA; MARÍA ISABEL GARCÍA-MORENO; JOSÉ MANUEL GARCÍA FERNÁNDEZ; JOSÉ KOVENSKY; MARÍA LAURA UHRIG

Synthesis of b-galactosylamides as ligands of the peanut lectin. Insights into the recognition process

CARBOHYDRATE RESEARCH; Lugar: Amsterdam; Año: 2017 vol. 443 p. 58 - 67

D. E. YERLEN; S. BARATA-VALLEJO; B. CAMPS; ALEJANDRO EZEQUIEL CRISTÓFALO; MARÍA EMILIA CANO; MARÍA LAURA UHRIG; ALBERTO POSTIGO

ELECTRON-CATALYZED RADICAL PERFLUOROALKYLATION OF ORGANIC SULFIDES. THE SERENDIPITOUS USE OF TMEDA/I2 COMPLEX AS RADICAL INITIATOR

Catalysis Science and Techonology; Año: 2017 vol. 7 p. 2274 - 2282

ROSALÍA AGUSTÍ; MARÍA EMILIA CANO; ALEJANDRO JAVIER CAGNONI; JOSÉ KOVENSKY; ROSA M. DE LEDERKREMER; MARÍA LAURA UHRIG

Multivalent sialylation of beta-thio-glycoclusters by Trypanosoma cruzi trans sialidase and analysis by High Performance Anion Exchange Chromatography

GLYCOCONJUGATE JOURNAL; Lugar: New York; Año: 2016 vol. 33 p. 809 - 818

CECILIA SAMANIEGO LÓPEZ; MARÍA AMPARO LAGO HUVELLE; MARÍA LAURA UHRIG; FEDERICO COLUCCIO LESCOW; CARLA CECILIA SPAGNUOLO

Recognition of saccharides in the NIR region with a novel fluorogenic boronolectin: in vitro and live cell labeling

CHEMICAL COMMUNICATIONS; Lugar: Cambridge; Año: 2015 vol. 2015 p. 4895 - 4898

MARÍA EMILIA CANO; ROSALÍA AGUSTÍ; ALEJANDRO JAVIER CAGNONI; MARÍA FLORENCIA TESORIERO; JOSÉ KOVENSKY; MARÍA LAURA UHRIG; ROSA MUCHNIK DE LEDERKREMER

Synthesis of divalent ligands of beta-thio- and beta-N-galactopyranosides and related lactosides and their evaluation as substrates and inhibitors of Trypanosoma cruzi trans-sialidase

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Frankfurt; Año: 2014 vol. 2014 p. 3073 - 3086

ALEJANDRO JAVIER CAGNONI; JOSÉ KOVENSKY; MARÍA LAURA UHRIG

Design and synthesis of hydrolytically stable multivalent ligands bearing thiodigalactoside analogues for peanut lectin and human galectin-3 binding

JOURNAL OF ORGANIC CHEMISTRY; Lugar: Washington; Año: 2014 vol. 2014 p. 6456 - 6467

LUIS CALLE; VIRGINIA ROLDÓS; JAVIER CAÑADA; MARÍA LAURA UHRIG; ALEJANDRO J. CAGNONI; VERÓNICA ELENA MANZANO; OSCAR VARELA; JESÚS JIMÉNEZ BARBERO

Escherichia coli beta-galactosidase inhibitors through modifications at the aglyconic moiety: experimental evidence of conformational distortion in the molecular recognition process.

CHEMISTRY-A EUROPEAN JOURNAL; Lugar: Weinheim; Año: 2013 vol. 19 p. 4262 - 4270

ALEJANDRO J. CAGNONI; OSCAR VARELA; JOSÉ KOVENSKY; MARÍA LAURA UHRIG

Synthesis and biological activity of divalent ligands based on 3-deoxy-4-thiolactose, an isosteric analogue of lactose

ORGANIC & BIOMOLECULAR CHEMISTRY; Lugar: Cambridge; Año: 2013 vol. 2013 p. 5500 - 5511

VERÓNICA ELENA MANZANO; MARÍA LAURA UHRIG; OSCAR VARELA

Convenient synthesis of 4-thiolactose, 3,4-dithiolactose and related thiooligosaccharides and disulfides. Inhibitory activity of the glycomimetics against a beta-galactosidase

ORGANIC & BIOMOLECULAR CHEMISTRY; Lugar: CAMBRIDGE; Año: 2012 vol. 10 p. 8884 - 8894

EVANGELINA REPETTO; VERÓNICA ELENA MANZANO; MARÍA LAURA UHRIG; OSCAR VARELA

Synthesis of branched dithiotrisaccharides via ring-opening reaction of sugar thiiranes

JOURNAL OF ORGANIC CHEMISTRY; Lugar: Washington; Año: 2012 vol. 77 p. 253 - 265

ALEJANDRO J. CAGNONI; OSCAR VARELA; MARÍA LAURA UHRIG; JOSÉ KOVENSKY

Efficient Synthesis of Thiolactoside Glycoclusters by Ruthenium-Catalyzed Cycloaddition of Disubstituted Alkynes on Carbohydrate Scaffolds

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim; Año: 2012 vol. 2013 p. 972 - 983

CAGNONI, ALEJANDRO JAVIER; VARELA, OSCAR; GOUIN, SEBASTIEN; KOVENSKY, JOSE;; UHRIG, MARIA;A LAURA

Synthesis of multivalent glycoclusters from 1-thio-b-D-galactose and their inhibitory activity against the b-galactosidase from E. coli

JOURNAL OF ORGANIC CHEMISTRY; Lugar: Columbus; Año: 2011 vol. 76 p. 3064 - 3077

MARÍA LAURA UHRIG; MARIO SIMIRGIOTIS; OSCAR VARELA

Enantiospecific synthesis of the sugar amino acid (2S, 5S)-5-(aminomethyl)-tetrahydrofuran-2-carboxylic acid

TETRAHEDRON-ASYMMETRY; Lugar: Amsterdam; Año: 2010 vol. 21 p. 2435 - 2440

CAGNONI, A. J.; UHRIG, M. L.; VARELA, O.

Synthesis of pentopyranosyl-containing thiodisaccharides. Inhibitory activity against beta-glycosidases.

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: New York, USA; Año: 2009 p. 6203 - 6212

REPETTO, E.; MARINO, C.; UHRIG, M. L.; VARELA, O.

Thiodisaccharides with galactofuranose or arabinofuranose as terminal units: Synthesis and inhibitory activity of an exo a-D-galactofuranosidase

BIOORGANIC & MEDICINAL CHEMISTRY.; Lugar: New York, USA; Año: 2009 p. 2703 - 2711

MANZANO, V. E.; UHRIG, M. L.; VARELA, O.

Straightforward synthesis of thiodisaccharides by ring-opening of sugar epoxides

JOURNAL OF ORGANIC CHEMISTRY; Lugar: Columbus, USA; Año: 2008 p. 7224 - 7235

REPETTO, E.; MARINO, C; UHRIG, M. L.; VARELA, O.

Two straightforward strategies for the synthesis of thiodisaccharides with a furanose unit as the nonreducing end

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim, Alemania; Año: 2008 vol. 2008 p. 540 - 547

MARÍA LAURA UHRIG; LASZLO SZILAGYI; KATALIN E. KOVER; OSCAR VARELA

Synthesis of non-glycosidic 4,6-thioether-linked disaccharides as hydrolytically stable glycomimetics

CARBOHYDRATE RESEARCH; Lugar: New York; Año: 2007 vol. 342 p. 1841 - 1849

MARÍA LAURA UHRIG; VERÓNICA ELENA MANZANO; OSCAR VARELA

Stereoselective Synthesis of 3-Deoxy-4-S-(1-4)-Thiodisaccharides and their Inhibitory Activities towards beta-Glycoside hydrolases

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY; Lugar: Weinheim, Alemania; Año: 2006 vol. 2006 p. 162 - 168

MARÍA LAURA UHRIG; OSCAR VARELA

Enantiospecific synthesis of both enantiomers of 2-benzyloxydihydropyran-3-ones form arabinose

SYNTHESIS-STUTTGART; Año: 2005 vol. 2005 p. 893 - 898

ALICIA S. COUTO; CAROLINA CAFFARO; MARÍA LAURA UHRIG; EMILIA KIMURA; VALNICE PERES; ALEJANDRO KATZIN; MASAE NISHIOKA; HIROSHI NONAMI; ROSA ERRA-BALSELLS

Glycosphingolipids in Plasmodium falciparum. Presence of an active glucosylceramide synthase

EUROPEAN JOURNAL OF BIOCHEMISTRY; Lugar: Copenhagen; Año: 2004 vol. 271 p. 2204 - 2214

CRISTIANA SANTOS DE MACEDO; MARIA LAURA UHRIG; EMILIA KIMURA; ALEJANDRO KATZIN

Characterization of the isoprenoid chain of coenzyme Q in Plasmodium falciparum

FEMS MICROBIOLOGY LETTERS; Lugar: Delft; Año: 2002 vol. 207 p. 13 - 20

UHRIG, M. L.; VARELA, O.

Michael addition of thiols to sugar enones. Synthesis of 3-deoxy-4-thiopyranosid- 2-uloses as key precursors of 3-deoxy- and C-2 branched-chain 4-thiosugars

AUSTRALIAN JOURNAL OF CHEMISTRY; Lugar: Melbourne; Año: 2002 p. 155 - 160

MARÍA LAURA UHRIG; OSCAR VARELA

Synthesis of glycosides of 3-deoxy-4-thiopentopyranosid-2-uloses and their reduction products: 3-deoxy-4-thiopentopyranosides

CARBOHYDRATE RESEARCH; Lugar: New York, USA; Año: 2002 vol. 337 p. 2069 - 2076

MOURA, I. C.; WUNDERLICH, G.; UHRIG, M. L.; COUTO, A. S.; PEREZ, V. J.; KATZIN, A. M.; KIMURA, E. A.

Limonene arrests parasite development and inhibits isoprenylation of proteins in Plasmodium falciparum

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington DC; Año: 2001 p. 2553 - 2558

COUTO, A. S.; KIMURA, E. A.; PERES, V. J.; UHRIG, M. L.; KATZIN, A. M.

Active isoprenoid pathway in the intra-erythrocytic stages of Plasmodium falciparum: presence of dolichols of 11 and 12 isoprene units.

BIOCHEMICAL JOURNAL; Lugar: London; Año: 1999 p. 629 - 637

MARIA LAURA UHRIG; ALICIA COUTO; MARIA JULIA MANSO ALVES; WALTER COLLI; ROSA MUCHNIK DE LEDERKREMER

Trypanosoma cruzi: Nitrogenous-base containing phosphatides in trypomastigote forms. Isolation and chemical analysis

EXPERIMENTAL PARASITOLOGY; Lugar: New York; Año: 1997 vol. 87 p. 8 - 19

MARIA LAURA UHRIG; ALICIA COUTO; WALTER COLLI; ROSA M. DE LEDERKREMER

Characterization of inositolphospholipids in Trypanosoma cruzi, trypomastigote forms

BIOCHIMICA ET BIOPHYSICA ACTA (ENZIMOLOGY); Lugar: New York; Año: 1996 vol. 1300 p. 133 - 139

MARÍA LAURA UHRIG; ALICIA S. COUTO; ROSA M. DE LEDERKREMER; BIANCA ZINGALES; WALTER COLLI

Metabolic labelling and partial characterization of a sulfoglycolipid in Trypanosoma cruzi trypomastigotes

CARBOHYDRATE RESEARCH; Lugar: Amsterdam; Año: 1992 vol. 231 p. 329 - 334

ALICIA S. COUTO; MARÍA LAURA UHRIG; ROSALÍA AGUSTÍ; MARCELO BEFUMO; BIANCA ZINGALES; WALTER COLLI; ROSA MUCHNIK DE LEDERKREMER

Trypanosoma cruzi: Incorporation of [3H]-palmitic acid and [3H]-galactose into components shed by trypomastigotes

Biochemistry International; Lugar: Marrickville; Año: 1991 vol. 24 p. 991 - 1002