INVESTIGADORES
FERNANDEZ Ariel
artículos
Título:
Defusing SARS-CoV-2: Emergency Brakes in a Vaccine Failure Scenario
Autor/es:
ARIEL FERNANDEZ
Revista:
ACS Pharmacology & Translational Science
Editorial:
American Chemical Society
Referencias:
Año: 2020 vol. 3 p. 1425 - 1426
ISSN:
2575-9108
Resumen:
Deactivation of primed SARS-CoV-2 prior to cell entry constitutes an emergency brake in COVID-19 infection if vaccine-induced antibodies fail to block recognition of the human angiotensin-converting enzyme 2 (hACE2) receptor. The timing and locus for the therapeutic intervention are dictated by the cell entry mechanism and by the selective advantage of the dominant D614G mutation.
