FRAUNHOFFER NICOLAS A.; CHANEZ, BRICE; TEYSSEDOU, CARLOS; IOVANNA, JUAN; MITRY, EMMANUEL; DUSETTI, NELSON

A Transcriptomic-Based Tool to Predict Gemcitabine Sensitivity in Advanced Pancreatic Adenocarcinoma

Gastroenterology; Año: 2023 vol. 164 p. 476 - 480

FRAUNHOFFER, NICOLAS A.; ABUELAFIA, ANALÍA MEILERMAN; BIGONNET, MARTIN; GAYET, ODILE; ROQUES, JULIE; NICOLLE, REMY; LOMBERK, GWEN; URRUTIA, RAUL; DUSETTI, NELSON; IOVANNA, JUAN

Multi-omics data integration and modeling unravels new mechanisms for pancreatic cancer and improves prognostic prediction

npj Precision Oncology; Año: 2022 vol. 6

FRAUNHOFFER, NICOLAS A.; ABUELAFIA, ANALÍA MEILERMAN; DUSETTI, NELSON; IOVANNA, JUAN

Limitation and challenges in using pancreatic cancer-derived organoids as a preclinical tool

Cancer Communications; Año: 2022 vol. 42 p. 1028 - 1031

FRAUNHOFFER, NICOLAS ALEJANDRO; ABUELAFIA, ANALÍA MEILERMAN; CHANEZ, BRICE; BIGONNET, MARTIN; GAYET, ODILE; ROQUES, JULIE; CHULUYAN, EDUARDO; DUSETTI, NELSON; IOVANNA, JUAN

Inhibition of glucuronidation in pancreatic cancer improves gemcitabine anticancer activity

Cancer Communications; Año: 2022 vol. 42 p. 1212 - 1216

HOARE, OWEN; FRAUNHOFFER, NICOLAS; ELKAOUTARI, ABDESSAMAD; GAYET, ODILE; BIGONNET, MARTIN; ROQUES, JULIE; NICOLLE, RÉMY; MCGUCKIN, COLIN; FORRAZ, NICO; SOHIER, EMILIE; TONON, LAURIE; WAJDA, PAULINE; BOYAULT, SANDRINE; ATTIGNON, VALÉRY; TABONE?EGLINGER, SÉVERINE; BARBIER, SANDRINE; MIGNARD, CAROLINE; DUCHAMP, OLIVIER; IOVANNA, JUAN; DUSETTI, NELSON J.

Exploring the complementarity of pancreatic ductal adenocarcinoma preclinical models

Cancers; Año: 2021 vol. 13

KAOUTARI, ABDESSAMAD EL; FRAUNHOFFER, NICOLAS A; HOARE, OWEN; TEYSSEDOU, CARLOS; SOUBEYRAN, PHILIPPE; GAYET, ODILE; ROQUES, JULIE; LOMBERK, GWEN; URRUTIA, RAUL; DUSETTI, NELSON; IOVANNA, JUAN

Metabolomic profiling of pancreatic adenocarcinoma reveals key features driving clinical outcome and drug resistance

EBioMedicine; Año: 2021 vol. 66

FRAUNHOFFER NICOLAS A.; CLOSA, DANIEL ; FOLCH-PUY, EMMA ; ABUELAFIA, ANALIA MEILERMAN; CALVO, EZEQUIEL LUIS ; CHULUYAN, EDUARDO; IOVANNA, JUAN

Targeting REG3β limits pancreatic ductal adenocarcinoma progression through CTGF downregulation

CANCER LETTERS; Lugar: Amsterdam; Año: 2021 vol. 521 p. 64 - 70

FRAUNHOFFER NICOLAS A.; ABUELAFIA, ANALIA MEILERMAN; TEYSSEDOU, CARLOS; CHULUYAN, EDUARDO HECTOR; BIGONNET, MARTIN; PALAZZO, LAURENT ; GAYET, ODILE; REMY, NICOLLE; CROS, JEROME; IOVANNA, JUAN; DUSETTI, NELSON

Squamousness gain defines pancreatic ductal adenocarcinoma hepatic metastases phenotype, and gemcitabine response

EUROPEAN JOURNAL OF CANCER; Lugar: Amsterdam; Año: 2021 vol. 155 p. 42 - 53

GAJATE, CONSUELO; GAYET, ODILE; FRAUNHOFFER, NICOLAS A.; IOVANNA, JUAN; DUSETTI, NELSON; MOLLINEDO, FAUSTINO

Induction of apoptosis in human pancreatic cancer stem cells by the endoplasmic reticulum-targeted alkylphospholipid analog edelfosine and potentiation by autophagy inhibition

Cancers; Año: 2021 vol. 13

TAKEISHI, KAZUKI; COLLIN DE L?HORTET, ALEXANDRA; WANG, YANG; HANDA, KAN; GUZMAN-LEPE, JORGE; MATSUBARA, KENTARO; MORITA, KAZUTOYO; JANG, SAE; HAEP, NILS; FLORENTINO, RODRIGO M.; YUAN, FANGCHAO; FUKUMITSU, KEN; TOBITA, KIMIMASA; SUN, WENDELL; FRANKS, JONATHAN; DELGADO, EVAN R.; SHAPIRO, ERIK M.; FRAUNHOFFER, NICOLAS A.; DUNCAN, ANDREW W.; YAGI, HIROSHI; MASHIMO, TOMOJI; FOX, IRA J.; SOTO-GUTIERREZ, ALEJANDRO

Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

Cell Reports; Año: 2020 vol. 31

FRAUNHOFFER, NICOLAS A.; ABUELAFIA, ANALÍA MEILERMAN; BIGONNET, MARTIN; GAYET, ODILE; ROQUES, JULIE; TELLE, EMMANUEL; SANTOFIMIA-CASTAÑO, PATRICIA; BORRELLO, MARÍA TERESA; CHULUYAN, EDUARDO; DUSETTI, NELSON; IOVANNA, JUAN

Evidencing a Pancreatic Ductal Adenocarcinoma Subpopulation Sensitive to the Proteasome Inhibitor Carfilzomib

CLINICAL CANCER RESEARCH; Año: 2020 vol. 26 p. 5506 - 5519

INSERRA, PABLO I.F.; CHARIF, SANTIAGO E.; FIDEL, VICTORIA; GIACCHINO, MARIELA; SCHMIDT, ALEJANDRO R.; VILLARREAL, FEDERICO M.; PROIETTO, SOFÍA; CORTASA, SANTIAGO A.; CORSO, MARÍA C.; GARIBOLDI, MARÍA C.; LEOPARDO, NOELIA P.; FRAUNHOFFER, NICOLÁS A.; DI GIORGIO, NOELIA P.; LUX-LANTOS, VICTORIA A.; HALPERIN, JULIA; VITULLO, ALFREDO D.; DORFMAN, VERÓNICA B.

The key action of estradiol and progesterone enables GnRH delivery during gestation in the South American plains vizcacha, Lagostomus maximus

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY; Año: 2020 vol. 200

FLORENTINO, RODRIGO; FRAUNHOFFER NICOLAS A.; MORITA, KAZUTOYO ; TAKEISHI, KAZUKI ; OSTROWSKA, ALINA ; ACHREJA, ABHINAV ; ANIMASAHUN, OLAMIDE ; HAEP, NILS; ARAZOV, SHOHRAT; AGARWAL, NANDINI; COLLIN DE LHORTET, ALEXANDRA ; GUZMAN-LEPE, JORGE; TAFALENG, EDGAR N. ; MUKHERJEE, AMITAVA ; TROY, KRIS ; BANERJEE, SWATI ; PARANJPE, SHIRISH ; MICHALOPOULOS, GEORGE K.; BELL, AARON; NAGRATH, DEEPAK ; HAINER, SARAH J. ; FOX, IRA J. ; SOTO-GUTIERREZ, ALEJANDRO

Cellular Location of HNF4A is Linked With Terminal Liver Failure in Humans

Hepatology Communication; Lugar: New York; Año: 2020

LAN, WENJUN; SANTOFIMIA-CASTAÑO, PATRICIA; XIA, YI; ZHOU, ZHENGWEI; HUANG, CAN; FRAUNHOFFER, NICOLAS; BAREA, DOLORES; CERVELLO, MELCHIORE; GIANNITRAPANI, LYDIA; MONTALTO, GIUSEPPE; PENG, LING; IOVANNA, JUAN

Targeting NUPR1 with the small compound ZZW-115 is an efficient strategy to treat hepatocellular carcinoma

CANCER LETTERS; Año: 2020

HUANG, CAN; LAN, WENJUN; FRAUNHOFFER, NICOLAS; MEILERMAN, ANALÍA; IOVANNA, JUAN; SANTOFIMIA-CASTAÑO, PATRICIA

Dissecting the Anticancer Mechanism of Trifluoperazine on Pancreatic Ductal Adenocarcinoma

Cancers; Lugar: Basel; Año: 2019 vol. 11

FRAUNHOFFER NICOLAS A.; ABUELAFIA, ANALIA MEILERMAN; BARRIENTOS, MARIANGEL; CIMERMAN, KAREN VERONICA; OLMOS, MARIA FLORENCIA; CHULUYAN, EDUARDO HECTOR; BARRIOS, MARCELA

Long-term apoptosis-related protein expression in the diabetic mouse ovary

PLOS ONE; Lugar: San Francisco; Año: 2018

AGARWAL, NANDINI; POPOVIC, BRANIMIR; MARTUCCI, NICOLE; FRAUNHOFFER NICOLAS A.; SOTO GUTIERREZ, ALEJANDRO

Biofabrication of Autologous Human Hepatocytes for Transplantation: How do we get there?

GENE EXPRESSION; Lugar: New York; Año: 2018

INSERRA PABLO IF.; CHARIF SANTIAGO; DI GIORGIO NOELIA P.; SAUCEDO LUCIA; SCHMIDT ALEJANDRO RAÚL; FRAUNHOFFER NICOLAS A.; HALPERIN JULIA; GARIBOLDI MARÍA CONSTANZA; LEOPARDO NOELIA P.; LUX-LANTOS VICTORIA; GONZALEZ CANDELA ROCIO; VITULLO ALFREDO D.; DORFMAN VERONICA B.

ERa and GnRH co-localize in the hypothalamic neurons of the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha)

JOURNAL OF MOLECULAR HISTOLOGY; Lugar: Berlin; Año: 2017

FRAUNHOFFER, NICOLAS ALEJANDRO; JENSEN, FEDERICO; LEOPARDO, NOELIA; INSERRA, PABLO IGNACIO FELIPE; ABUELAFIA, ANALIA MEILERMAN; ESPINOSA, MARIA BEATRIZ; CHARIF, SANTIAGO ELIAS; DORFMAN, VERONICA BERTA; VITULLO, ALFREDO DANIEL

Hormonal behavior correlates with follicular recruitment at mid-gestation in the South American plains vizcacha, Lagostomus maximus (Rodentia, Caviomorpha).

GENERAL AND COMPARATIVE ENDOCRINOLOGY; Año: 2017

FRAUNHOFFER NICOLAS A.; MEILERMAN ABUELAFIA ANALIA.; STELLA INES; GALLIANO SILVIA; BARRIOS MARCELA; VITULLO ALFREDO D.

Identification of germ cell-specific VASA and IFITM3 proteins in human ovarian endometriosis

Journal of Ovarian Research; Lugar: Berlin ; Año: 2015 vol. 8

DORFMAN VERONICA B.; SAUCEDO LUCIA; DI GIORGIO NOELIA P.; INSERRA PABLO IF.; FRAUNHOFFER NICOLAS.; LEOPARDO NOELIA P.; HALPERIN JULIA; LUX-LANTOS VICTORIA; VITULLO ALFREDO D.

Variation in progesterone receptors and GnRH expression in the hypothalamus of pregnant South American plains vizcacha, Lagostomus maximus (Mammalia, Rodentia)

BIOLOGY OF REPRODUCTION; Lugar: Madison; Año: 2013 vol. 89 p. 115 - 129

HALPERIN JULIA; DORFMAN VERONICA B.; FRAUNHOFFER NICOLAS.; VITULLO ALFREDO D.

Estradiol, progesterone and prolactin modulate mammary gland morphogenesis in adult female plains vizcacha

JOURNAL OF MOLECULAR HISTOLOGY; Lugar: Berlin; Año: 2013 vol. 44 p. 299 - 310

GONZALEZ CANDELA ROCIO; MUSCARSEL MARIA L.; FRAUNHOFFER NICOLAS A.; LEOPARDO NOELIA P.; VITULLO ALFREDO D.

Germ cell differentiation and proliferation in the developing testis of the South American plains viscacha, Lagostomus maximus (Mammalia, Rodentia)

ZYGOTE; Lugar: Cambridge; Año: 2011 p. 1 - 9

DORFMAN VERONICA B.; FRAUNHOFFER NICOLAS A.; INSERRA PABLO IF.; LOIDL CESAR F.; VITULLO ALFREDO D.

Histological characterization of gonadotropin-releasing hormone (GnRH) in the hypothalamus of the South American plains vizcacha (Lagostomus maximus)

JOURNAL OF MOLECULAR HISTOLOGY; Lugar: Berlin; Año: 2011 vol. 42 p. 311 - 321

ESPINOSA MARÍA B.; FRAUNHOFFER NICOLAS A.; LEOPARDO NOELIA P.; VITULLO ALFREDO D.; WILLIS MIGUEL A.

The ovary of Lagostomus maximus (Mammalia, Rodentia): an analysis by confocal microscopy

BIOCELL; Lugar: Mendoza; Año: 2011 vol. 35 p. 37 - 42