INVESTIGADORES
CHULUYAN Hector Eduardo
congresos y reuniones científicas
Título:
Posibles blancos terapéuticos para modular la respuesta inmune
Autor/es:
CHULUYAN, H. EDUARDO
Lugar:
Tandil, Provincia de Buenos Aires, Argentina
Reunión:
Congreso; XL REUNION ANUAL DE LA SOCIEDAD ARGENTINA DE FARMACOLOGIA EXPERIMENTAL; 2008
Institución organizadora:
SOCIEDAD ARGENTINA DE FARMACOLOGIA EXPERIMENTAL
Resumen:
Advances in molecular technology have facilitated identification of novel therapeutic targets including cell subsets, cytokines and other molecules. Several new therapeutic agents are protein-based drugs termed biologicals‟ and target TNF (infliximab, adalimumab, etanercept), IL-1 (anakinra), IL-6 (Tocilizumab), CD20 (rituximab), CTLA-4/Ig (abatacept), CD4 (keliximab), ICAM-1 (alefacept), among others. Evidence about the benefits of these drugs is accumulating. However, they are not risk-free.
