NATALIA ARANA; BÁRBARA PEREZ MORA; VALENTÍN PERMINGEAT; ROCÍO GIORDANO; MALENA CALDERONE; MARISEL TUTTOBENE; SEBASTIÁN KLINKE; JIMENA RINALDI; GABRIELA MÜLLER; MARÍA A. MUSSI

Light regulation in critical human pathogens of clinical relevance such as Acinetobacter baumannii, Staphylococcus aureus and Pseudomonas aeruginosa

Photochemical and Photobiological Sciences; Lugar: CAMBRIDGE; Año: 2023 vol. 22 p. 2019 - 2036

GABRIELA LLAUGER; ROBERTO MELERO; DEMIÁN MONTI; GABRIELA SYCZ; CRISTIÁN HUCK-IRIART; MARÍA L. CERUTTI; SEBASTIÁN KLINKE; EVELYN MIKKELSEN; ARIEL TIJMAN; ROCÍO ARRANZ; VICTORIA ALFONSO; SOFÍA M. ARELLANO; FERNANDO A. GOLDBAUM; YANN G. STERCKX; JOSÉ M. CARAZO; SERGIO B. KAUFMAN; PABLO D. DANS; MARIANA DEL VAS; LISANDRO H. OTERO

A fijivirus major viroplasm protein shows RNA-stimulated ATPase activity by adopting pentameric and hexameric assemblies of dimers

mBio; Lugar: Washington DC; Año: 2023 vol. 14

MARIANA SACERDOTI; LISSY Z. F. GROSS; ANDREW M. RILEY; KARIN ZEHNDER; ABHIJEET GHODE; SEBASTIÁN KLINKE; GANESH SRINIVASAN ANAND; KRISTINA PARIS; ANGELIKA WINKEL; AMANDA K. HERBRAND; H. YASMIN GODAGE; GYLES E. COZIER; EVELYN SUESS; JOERG O. SCHULZE; DANIEL PASTOR-FLORES; MARIELA BOLLINI; MARÍA VICTORIA CAPPELLARI; DMITRI SVERGUN; MELISSA A. GRAEWERT; PEDRO F. ARAMENDIA; ALEJANDRO E. LEROUX; BARRY V. L. POTTER; CARLOS J. CAMACHO; RICARDO M. BIONDI

Modulation of the substrate specificity of the kinase PDK1 by distinct conformations of the full-length protein

SCIENCE SIGNALING; Lugar: Washington; Año: 2023 vol. 16

FLORENCIA BRUNETTI; BÁRBARA GHIGLIONE; DEREJE D. GUDETA; GABRIEL GUTKIND; LUCA GUARDABASSI; SEBASTIÁN KLINKE *CO-CORRESPONDING AUTHOR; PABLO POWER *CO-CORRESPONDING AUTHOR

Biochemical and structural characterization of CRH-1, a carbapenemase from Chromobacterium haemolyticum related to KPC beta-lactamases

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2023 vol. 67

MARÍA L. DARRIBA; CELESTE PUEBLAS CASTRO; LORENA M. CORIA; LAURA BRUNO; MARÍA L. CERUTTI; LISANDRO H. OTERO; LUCÍA B. CHEMES; RODOLFO M. RASIA; SEBASTIÁN KLINKE; JULIANA CASSATARO; KARINA A. PASQUEVICH

A disordered region retains the protease inhibitor activity and the capacity to induce CD8+ T cells in vivo of U-Omp19

Computational and Structural Biotechnology Journal; Lugar: Amsterdam; Año: 2022 vol. 20 p. 5098 - 5114

LAKSHMI SRINIVASAN; VANINA ALZOGARAY; DAKSHNAMURTHY SELVAKUMAR; SARA NATHAN; JESSE YODER; KATHARINE M. WRIGHT; SEBASTIÁN KLINKE; JUSTIN N. NWAFOR; MARÍA S. LABANDA; FERNANDO A. GOLDBAUM; ARNE SCHÖN; ERNESTO FREIRE; GORDON F. TOMASELLI; L. MARIO AMZEL; MANU BEN-JOHNY; SANDRA GABELLI

Development of High affinity Nanobodies Specific for NaV1.4 and NaV1.5 Voltage-Gated Sodium Channel Isoforms

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2022 vol. 298

VALERIA CONFORTE; LISANDRO H. OTERO; LAILA TOUM; SERENA SIRIGU; GIULIANO T. ANTELO; JIMENA RINALDI; SABRINA FOSCALDI; SEBASTIÁN KLINKE; LEONARD CHAVAS; ADRIAN A. VOJNOV; FERNANDO A. GOLDBAUM; FLORENCIA MALAMUD; HERNÁN R. BONOMI

Pr-favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence-associated mechanisms

FEBS JOURNAL; Lugar: Londres; Año: 2021 vol. 288 p. 5986 - 6002

JIMENA RINALDI; IGNACIO FERNÁNDEZ; HEEWHAN SHIN; GABRIELA SYCZ; SEMINI GUNAWARDANA; INDIKA KUMARAPPERUMA; JUAN M. PAZ; LISANDRO H. OTERO; MARÍA L. CERUTTI; ÁNGELES ZORREGUIETA; ZHONG REN; SEBASTIÁN KLINKE *CO-CORRESPONDING AUTHOR; XIAOJING YANG *CO-CORRESPONDING AUTHOR; FERNANDO A. GOLDBAUM *CO-CORRESPONDING AUTHOR

Dimer asymmetry and light activation mechanism in Brucella blue-light sensor histidine kinase

mBio; Año: 2021 vol. 12

BARBARA GHIGLIONE; MARÍA M. RODRÍGUEZ; FLORENCIA BRUNETTI; KRISZTINA M. PAPP-WALLACE; AYUMI YOSHIZUMI; YOSHIKAZU ISHII; ROBERT A. BONOMO; GABRIEL GUTKIND; SEBASTIÁN KLINKE *CO-CORRESPONDING AUTHOR; PABLO POWER *CO-CORRESPONDING AUTHOR

Structural and biochemical characterization of the novel CTX-M-151 extended-spectrum beta-lactamase and its inhibition by Avibactam

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Año: 2021 vol. 65

ALEJO R. GIANOTTI; SEBASTIÁN KLINKE; MARIO R. ERMÁCORA

The structure of unliganded sterol carrier protein 2 from Yarrowia lipolytica unveils a mechanism for binding site occlusion

JOURNAL OF STRUCTURAL BIOLOGY; Lugar: Amsterdam; Año: 2021 vol. 213

RAMIRO LORENZO; LUCAS A. DEFELIPE; LUCIO ALIPERTI; STEPHAN NIEBLING; TÂNIA F. CUSTÓDIO; CHRISTIAN LÖW; JENNIFER J. SCHWARZ; KIM REMANS; PATRICIO O. CRAIG; LISANDRO H. OTERO; SEBASTIÁN KLINKE; MARÍA GARCÍA-ALAI; IGNACIO E. SÁNCHEZ; LEONARDO G. ALONSO

Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif

JOURNAL OF BIOLOGICAL CHEMISTRY; Lugar: Bethesda, Maryland; Año: 2021 vol. 294

LISANDRO H. OTERO; SABRINA FOSCALDI; GIULIANO T. ANTELO; GERMÁN L. ROSANO; SERENA SIRIGU; SEBASTIÁN KLINKE; LUCAS A. DEFELIPE; MAXIMILIANO SÁNCHEZ-LAMAS; GIOVANNI BATTOCCHIO; VALERIA CONFORTE; ADRIÁN A. VOJNOV; LEONARD CHAVAS; FERNANDO A. GOLDBAUM; MARÍA ANDREA MROGINSKI; JIMENA RINALDI; HERNÁN BONOMI

Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level

Science Advances; Año: 2021 vol. 7

ALEJANDRO J. CAGNONI; EMILIANO D. PRIMO; SEBASTIÁN KLINKE; MARÍA E. CANO; WALTER GIORDANO; KARINA V. MARIÑO; JOSÉ KOVENSKY; FERNANDO A. GOLDBAUM; MARÍA L. UHRIG; LISANDRO H. OTERO

Crystal structures of peanut lectin in the presence of synthetic beta-N- and beta-S-galactosides disclose evidences for the recognition of different glycomimetic ligands

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY; Lugar: Londres; Año: 2020 vol. 76 p. 1080 - 1091

VANESA ZYLBERMAN; SANTIAGO SANGUINETI; ANDREA V. PONTORIERO; SANDRA V. HIGA; MARÍA L. CERUTTI; SUSANA M. MORRONE SEIJO; ROMINA PARDO; LUCIANA MUÑOZ; MARÍA E. ACUÑA INTRIERI; VANINA A. ALZOGARAY; MARTÍN M. AVARO; ESTEFANÍA BENEDETTI; PAULA M. BERGUER; LAURA BOCANERA; LUCAS BUKATA; MARINA S. BUSTELO; ANA M. CAMPOS; MARIANA COLONNA; ELISA CORREA; LUCÍA CRAGNAZ; MARÍA E. DATTERO; MARÍA DELLAFIORE; SABRINA FOSCALDI; JOAQUÍN V. GONZÁLEZ; LUCIANO L. GUERRA; SEBASTIÁN KLINKE; MARÍA S. LABANDA; CONSTANZA LAUCHÉ; JUAN C. LÓPEZ; ANABELA M. MARTÍNEZ; LISANDRO H. OTERO; ELÍAS H. PEYRIC; PABLO F. PONZIANI; ROMINA RAMONDINO; JIMENA RINALDI; SANTIAGO RODRÍGUEZ; JAVIER E. RUSSO; MARA L. RUSSO; SOLEDAD L. SAAVEDRA; MAURICIO SEIGELCHIFER; SANTIAGO SOSA; CLAUDIO VILARIÑO; PATRICIA LÓPEZ BISCAYART; ESTEBAN CORLEY; LINUS SPATZ; ELSA G. BAUMEISTER; FERNANDO A. GOLDBAUM

Development of a hyperimmune equine serum therapy for COVID-19 in Argentina

MEDICINA (BUENOS AIRES); Lugar: Buenos Aires; Año: 2020 vol. 80 p. 1 - 6

LEONARDO PELLIZZA; JOSÉ L. LÓPEZ; SUSANA VÁZQUEZ; GABRIELA SYCZ; BEATRIZ G. GUIMARÃES; JIMENA RINALDI; FERNANDO A. GOLDBAUM; MARTÍN ARAN *CO-CORRESPONDING AUTHOR; WALTER P. MAC CORMACK *CO-CORRESPONDING AUTHOR; SEBASTIÁN KLINKE *CO-CORRESPONDING AUTHOR

Structure of the putative long tail fiber receptor-binding tip of a novel temperate bacteriophage from the Antarctic bacterium Bizionia argentinensis JUB59

JOURNAL OF STRUCTURAL BIOLOGY; Lugar: Amsterdam; Año: 2020 vol. 212

JUSTO OLMOS; MARÍA F. PIGNATARO; ANA B. BENÍTEZ DOS SANTOS; MAURO BRINGAS; SEBASTIÁN KLINKE; LAURA KAMENETZKY; FRANCISCO VELAZQUEZ; JAVIER SANTOS

A Highly Conserved Iron-Sulfur Cluster Assembly Machinery between Humans and Amoeba Dictyostelium discoideum: The Characterization of Frataxin

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; Lugar: Basel; Año: 2020 vol. 21

ANTONELA R. PALACIOS; MARÍA F. MOJICA; ESTEFANÍA GIANNINI; MAGDALENA A. TARACILA; CHRISTOPHER R. BETHEL; PEDRO M. ALZARI; LISANDRO OTERO; SEBASTIÁN KLINKE; LETICIA I. LLARRULL; ROBERT A. BONOMO; ALEJANDRO VILA

The reaction mechanism of metallo-beta-lactamases is tuned by the conformation of an active site mobile loop

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Lugar: Washington; Año: 2019 vol. 63

JAVIER M. GONZÁLEZ; ROMINA B. AGOSTINI; CLARISA E. ALVAREZ; SEBASTIÁN KLINKE; CARLOS S. ANDREO; VALERIA CAMPOS-BERMUDEZ

Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays

FEBS JOURNAL; Lugar: Londres; Año: 2019 vol. 286 p. 3255 - 3271

SANTIAGO SOSA; ANDRÉS H. ROSSI; ALAN M. SZALAI; SEBASTIÁN KLINKE; JIMENA RINALDI; ANA FARÍAS; PAULA BERGUER; ALEJANDRO NADRA; FERNANDO D. STEFANI; FERNANDO A. GOLDBAUM; HERNÁN R. BONOMI

Asymmetric bifunctional protein nanoparticles through redesign of self-assembly

Nanoscale Advances; Lugar: Londres; Año: 2019 vol. 1 p. 1833 - 1846

MARÍA I. SERER; MARIELA DEL C. CARRICA; JOERG TRAPPE; SANDRA LÓPEZ ROMERO; HERNÁN R. BONOMI; SEBASTIÁN KLINKE; MARÍA L. CERUTTI; FERNANDO A. GOLDBAUM

A high-throughput screening for inhibitors of riboflavin synthase identifies novel antimicrobial compounds to treat brucellosis

FEBS JOURNAL; Lugar: Londres; Año: 2019 vol. 286 p. 2522 - 2535

MELINA RUGGIERO; KRISZTINA M. PAPP-WALLACE; FLORENCIA BRUNETTI; MELISSA D. BARNES; ROBERT A. BONOMO; GABRIEL GUTKIND; SEBASTIÁN KLINKE *CO-CORRESPONDING AUTHOR; PABLO POWER *CO-CORRESPONDING AUTHOR

Structural insights into the inhibition of the extended-spectrum beta-lactamase PER-2 by Avibactam

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; Año: 2019 vol. 63

SEBASTIÁN KLINKE; JIMENA RINALDI; FERNANDO A. GOLDBAUM; SEBASTIÁN SUÁREZ; LISANDRO OTERO

An all-inclusive and straightway laboratory activity to solve the three-dimensional crystal structure of a protein

Biochemistry and Molecular Biology Education; Lugar: Hoboken, Nueva Jersey; Año: 2019 vol. 47 p. 700 - 707

MARÍA G. HERRERA; MARTÍN E. NOGUERA; KARL E. SEWELL; WILLIAM A. AGUDELO SUÁREZ; LUCIANA CAPECE; SEBASTIÁN KLINKE; JAVIER SANTOS

Structure of the human ACP-ISD11 heterodimer

BIOCHEMISTRY; Lugar: Washington; Año: 2019 vol. 58 p. 4596 - 4609

EMILIANO PRIMO; LISANDRO OTERO; FRANCISCO RUIZ; SEBASTIÁN KLINKE; WALTER GIORDANO

The disruptive effect of lysozyme on the bacterial cell wall explored by an in-silico structural outlook

BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION; Lugar: New York; Año: 2018 vol. 46 p. 83 - 90

AMANDA SAPP; JOSÉ C. HUGUET-TAPIA; MAXIMILIANO SÁNCHEZ-LAMAS; GIULIANO T. ANTELO; EMILIANO PRIMO; JIMENA RINALDI; SEBASTIÁN KLINKE; FERNANDO A. GOLDBAUM; HERNÁN R. BONOMI; BRENT C. CHRISTNER; LISANDRO OTERO

Draft genome sequence of Methylobacterium sp. strain V23, isolated from accretion ice of the Antarctic subglacial Lake Vostok

Genome Announcements; Año: 2018 vol. 6

ANDRÉS ESPINOZA-CARA; ULISES ZITARE; DAMIÁN ALVAREZ-PAGGI; SEBASTIÁN KLINKE; LISANDRO OTERO; DANIEL H. MURGIDA; ALEJANDRO VILA

Engineering a bifunctional copper site in the cupredoxin fold by loop-directed mutagenesis

Chemical Science; Lugar: Londres; Año: 2018 vol. 9 p. 6692 - 6702

JIMENA RINALDI; IGNACIO FERNÁNDEZ; LUCÍA M. POTH; WILLIAM E. SHEPARD; MARTIN SAVKO; FERNANDO A. GOLDBAUM; SEBASTIÁN KLINKE

Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state

Biochemistry and Biophysics Reports; Año: 2018 vol. 16 p. 39 - 43

MARÍA L. CERUTTI; LISANDRO OTERO; CLARA SMAL; LEONARDO PELLIZA; FERNANDO A. GOLDBAUM; SEBASTIÁN KLINKE *CO-CORRESPONDING AUTHOR; MARTIN ARAN *CO-CORRESPONDING AUTHOR

Structural and functional characterization of a cold adapted TPM-domain with ATPase/ADPase activity

JOURNAL OF STRUCTURAL BIOLOGY; Lugar: Amsterdam; Año: 2017 vol. 197 p. 201 - 209

ANABEL SOLDANO; SEBASTIÁN KLINKE; LISANDRO OTERO; MARIO RIVERA; DANIELA L. CATALANO-DUPUY; EDUARDO A. CECCARELLI

Structural and mutational analyses of the Leptospira interrogans virulence-related heme oxygenase provide insights into its catalytic mechanism

PLOS ONE; Lugar: San Francisco; Año: 2017 vol. 12

JIMENA RINALDI; MEHRNOOSH ARRAR; GABRIELA SYCZ; MARÍA L. CERUTTI; PAULA BERGUER; GASTÓN PARIS; DARÍO A. ESTRÍN; MARCELO A. MARTÍ; SEBASTIÁN KLINKE; FERNANDO A. GOLDBAUM

Structural insights into the HWE histidine kinase family: The Brucella blue light-activated histidine kinase domain

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2016 vol. 428 p. 1165 - 1179

LISANDRO OTERO; SEBASTIÁN KLINKE; JIMENA RINALDI; FRANCISCO VELÁZQUEZ-ESCOBAR; MARÍA ANDREA MROGINSKI; MARÍA FERNÁNDEZ LÓPEZ; FLORENCIA MALAMUD; ADRIAN A. VOJNOV; PETER HILDEBRANDT; FERNANDO A. GOLDBAUM; HERNÁN R. BONOMI

Structure of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris provides clues to its long-range signaling mechanism

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2016 vol. 428 p. 3702 - 3720

ANDRÉS E. IBÁÑEZ; LORENA M. CORIA; MARIANELA V. CARABAJAL; MARÍA V. DELPINO; GABRIELA S. RISSO; PAULA GONZALEZ COBIELLO; JIMENA RINALDI; PAULA BARRIONUEVO; LAURA BRUNO; FERNANDA M. FRANK; SEBASTIÁN KLINKE; FERNANDO A. GOLDBAUM; GABRIEL BRIONES; GUILLERMO H. GIAMBARTOLOMEI; KARINA A. PASQUEVICH; JULIANA CASSATARO

A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggers specific mucosal immune responses

JOURNAL OF CONTROLLED RELEASE; Lugar: Amsterdam; Año: 2015 vol. 220 p. 18 - 28

IGNACIO FERNÁNDEZ; LISANDRO OTERO; SEBASTIÁN KLINKE; MARIELA DEL C. CARRICA; FERNANDO A. GOLDBAUM

Snapshots of conformational changes shed light into the NtrX receiver domain signal transduction mechanism (ARTICULO DESTACADO COMO TAPA DE REVISTA)

JOURNAL OF MOLECULAR BIOLOGY; Lugar: Amsterdam; Año: 2015 vol. 427 p. 3258 - 3272

ZHENGGANG HAN; NAOKI SAKAI; LARS BOETTGER; SEBASTIÁN KLINKE; JOACHIM HAUBER; ALFRED TRAUTWEIN; ROLF HILGENFELD

Crystal structure of the peroxo-diiron(III) intermediate of Deoxyhypusine hydroxylase, an oxygenase involved in hypusination

STRUCTURE WITH FOLDING & DESIGN.; Lugar: United States; Año: 2015 vol. 23 p. 882 - 892

SEBASTIÁN KLINKE *CO-CORRESPONDING AUTHOR; NICOLAS FOOS; JIMENA RINALDI; GASTÓN PARIS; FERNANDO A. GOLDBAUM; PIERRE LEGRAND; BEATRIZ G. GUIMARÃES *CO-CORRESPONDING AUTHOR; ANDREW THOMPSON

S-SAD phasing of monoclinic histidine kinase from Brucella abortus combining data from multiple crystals and orientations: an example of data collection strategy and a posteriori analysis of different data combinations

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY; Lugar: Londres; Año: 2015 vol. 71 p. 1433 - 1443

SEBASTIÁN KLINKE; LISANDRO OTERO; JIMENA RINALDI; SANTIAGO SOSA; BEATRIZ G. GUIMARÃES; WILLIAM E. SHEPARD; FERNANDO A. GOLDBAUM; HERNÁN R. BONOMI

Crystallization and preliminary X-ray characterization of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris pv. campestris

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS; Lugar: Londres; Año: 2014 vol. 70 p. 1636 - 1639

MARÍA I. SERER; HERNÁN R. BONOMI; BEATRIZ G. GUIMARÃES; ROLANDO C. ROSSI; FERNANDO A. GOLDBAUM; SEBASTIÁN KLINKE

Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility (ARTICULO DESTACADO COMO TAPA DE REVISTA)

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY; Lugar: Londres; Año: 2014 vol. 70 p. 1419 - 1434

MARTIN ARAN; CLARA SMAL; LEONARDO PELLIZA; MARIANA GALLO; LISANDRO OTERO; SEBASTIÁN KLINKE; FERNANDO A. GOLDBAUM; ESTEBAN ITHURRALDE; ANDRÉS BERCOVICH; WALTER MAC CORMACK; ADRIÁN TURJANSKI; DANIEL O. CICERO

Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand-alone TPM domain

Proteins: Structure, Function, and Bioinformatics; Año: 2014 vol. 82 p. 3062 - 3078

FEDERICO PEREZ DE BERTI; STEFANO CAPALDI; RAUL FERREYRA; NOELIA BURGARDT; JUAN P. ACIERNO; SEBASTIÁN KLINKE; HUGO L. MONACO; MARIO R. ERMÁCORA

The crystal structure of sterol carrier protein 2 from Yarrowia lipolytica and the evolutionary conservation of a large, non-specific lipid-binding cavity

Journal of Structural and Functional Genomics; Año: 2013 vol. 14 p. 145 - 153

JIMENA RINALDI; MARIANA GALLO; SEBASTIÁN KLINKE; GASTÓN PARIS; HERNÁN R. BONOMI; ROBERTO A. BOGOMOLNI; DANIEL O. CICERO; FERNANDO A. GOLDBAUM

The Beta-Scaffold of the LOV Domain of the Brucella Light-Activated Histidine Kinase Is a Key Element for Signal Transduction

JOURNAL OF MOLECULAR BIOLOGY; Lugar: San Diego, CA; Año: 2012 vol. 420 p. 112 - 127

HERNAN RUY BONOMI; MARIA INES MARCHESINI; SEBASTIAN KLINKE; JUAN E. UGALDE; VANESA ZYLBERMAN; RODOLFO A. UGALDE; DIEGO J. COMERCI; FERNANDO ALBERTO GOLDBAUM

An atypical riboflavin pathway is essential for Brucella abortus virulence

PLOS ONE; Año: 2010 vol. 5 p. 9435 - 9435

MARÍA E. PRIMO; SEBASTIÁN KLINKE; MAURICIO P. SICA; FERNANDO A. GOLDBAUM; JEAN JAKONCIC; EDGARDO POSKUS; MARIO R. ERMÁCORA

Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2008 vol. 283 p. 4674 - 4681

JUAN P. ACIERNO; BRADFORD C. BRADEN; SEBASTIÁN KLINKE; FERNANDO A. GOLDBAUM; ANA A. CAUERHFF

Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies

JOURNAL OF MOLECULAR BIOLOGY; Año: 2007 vol. 374 p. 130 - 146

SEBASTIÁN KLINKE; VANESA ZYLBERMAN; HERNÁN R. BONOMI; ILKA HAASE; BEATRIZ G. GUIMARAES; BRADFORD C. BRADEN; ADELBERT BACHER; MARKUS FISCHER; FERNANDO A. GOLDBAUM

Structural and kinetic properties of Lumazine synthase isoenzymes in the order Rhizobiales (ARTICULO DESTACADO COMO TAPA DE REVISTA)

JOURNAL OF MOLECULAR BIOLOGY; Año: 2007 vol. 373 p. 664 - 680

VANESA ZYLBERMAN; SEBASTIÁN KLINKE; ILKA HAASE; ADELBERT BACHER; MARKUS FISCHER; FERNANDO A. GOLDBAUM

Evolution of vitamin B2 biosynthesis: 6,7-dimethyl-8-ribityllumazine synthases of Brucella

JOURNAL OF BACTERIOLOGY; Año: 2006 vol. 188 p. 6135 - 6142

SEBASTIÁN KLINKE; VANESA ZYLBERMAN; DANIEL R. VEGA; BEATRIZ G. GUIMARÃES; BRADFORD C. BRADEN; FERNANDO A. GOLDBAUM

Crystallographic studies on decameric Brucella spp. Lumazine synthase: a novel quaternary arrangement evolved for a new function?

JOURNAL OF MOLECULAR BIOLOGY; Año: 2005 vol. 353 p. 124 - 137

VANESA ZYLBERMAN; PATRICIO O. CRAIG; SEBASTIÁN KLINKE; BRADFORD C. BRADEN; ANA A. CAUERHFF; FERNANDO A. GOLDBAUM

High order quaternary arrangement confers increased structural stability to Brucella sp. lumazine synthase

JOURNAL OF BIOLOGICAL CHEMISTRY; Año: 2004 vol. 279 p. 8093 - 8101