MICROCEPHALY INFANT MORTALITY IN BRAZIL BEFORE ZIKA OUTBREAK

DIPIERRI JOSÉ EDGARDO; BRONBERG RUBÉN; CHAPUR, VALERIA FERNANDA; SCHULER-FACINI, LAVINIA

Revista de la Facultad de Ciencias Médicas

Facultad de Ciencias Médicas. Universidad Nacional de Córdoba

Lugar: Córdoba; Año: 2019 vol. 76 p. 217 - 221

0014-6722

Introduction: We present temporal and spatial variation of deaths from microcephaly inchildren under 1 year of age is analyzed at regional, state, and municipal level in the preZika period in Brazil.Materials and Methods: Data on births and deaths of infants with microcephaly wasobtained from DATASUS from 1996 to 2013. Infant mortality rate from microcephaly(IMR-M) was estimated at Region, Federative Unit (UF), and Municipality level. Seculartrend (ST) and risk of death variation were estimated using a Poisson regression model.Satscan software was used to obtain a statistic spatial scan for the Poisson model.Results: IMR-M shows a non-significant negative ST in the Southeast, South and CentralWest Regions of Brazil. A greater IMR-M risk of death variation is found in the North andNortheast Regions. Most UFs in the Southeast, South and Central West Regions showeda negative ST, in contrast to what occurs in the UFs of the North and Northeast Regionsshowed a positive ST. Six high risk significant clusters were found: 3 in the NorthNortheast and 3 in the South-SouthWest-Center-West.Conclusions: The North and Northeast Regions showed positive ST for IRM-M and higherdeath risk, which was not observed in the other regions. Cluster distribution for higherIMR-M and risk resembles the distribution of the microcephaly and Zika cases in theoutbreak period.