INSTITUTO DE PROCESOS BIOTECNOLOGICOS Y QUIMICOS ROSARIO
Unidad Ejecutora - UE
congresos y reuniones científicas
Ionic Liquids as Co-surfactants in the Design of Aqueous Micellar Extraction Systems
FILIPA A. VICENTE; LUCIANA PELLEGRINI MALPIEDI; FRANCISCA A. SILVA; ADALBERTO PESSOA JR; JOÃO A.P. COUTINHO; SÓNIA P.M. VENTURA
Congreso; 2nd EuCheMS Congress on Green and Sustainable Chemistry; 2015
Aqueous micellar two-phase systems (AMTPS) using surfactants are advantageous extraction systems, since they are mostly composed of water, emerging as an appellative type of liquid-liquid extraction (LLE). A plethora of biomolecules have already been separated and purified using these systems with several surfactants. AMTPS composed of two surfactants enhanced the extraction of biomolecules, hence exploiting the advantage of introducing ionic liquids (ILs) as a new class of co-surfactants came as an attractive alternative due to their unique properties. Thus, the objective of this work is to develop a new technology to be applied into the extraction field. Herein, two families of ILs, namely the [Cnmim] and phosphonium were applied in the design of new AMTPS, based on Triton X-114 as main surfactant. To evaluate the potential of this new LLE system, the partition and purification of different (bio)molecules was analyzed, considering the effect of the ILs as co-surfactants in the coexistence curves and their impact upon the solutes partition. Therefore, two (bio)molecules, cytochrome c (Cyt c) and Rhodamine 6G (R6G), are used in order to study their partition coefficients (K) and selectivities (SR6G/Cyt c) in the mentioned AMTPS. The obtained results clearly demonstrate that ILs have an important effect on the Tcloud. The presence of ILs as co-surfactants is able not only to enhance the KCyt c (indicated as log KCyt c) from -0.587 ± 0.117 up to -1.510 ± 0.139, but also to improve the SR6G/Cyt c from 925.25 up to 3418.89.