Dissolved Oxygen Dynamic Model for Endospore-Forming Bacteria Batch Bioprocess

FERNANDO A. DI SCIASCIO; ALEX ALZATE; ADRIANA N. AMICARELLI

Medellín

Congreso; XVII Latin American Conference of Automatic Control (CLCA); 2016

EAFIT

This paper extends and generalizes a model of Dissolved Oxygen (DO) dynamic developed for the δ - endotoxins of Bacillus thuringiensis (Bt) batch production process to a DO dynamical model that can be used for a broad class aerobic Endospore-forming Bacteria (AEFB). The most significant feature of this type of microorganism is the endospores generation in their life cycle. The generalization of the model allows to use the same parametric model structure for process control and state estimation purposes in a considerable variety of AEFB batch bioprocesses by selecting an appropriate set of parameters for each specific bioprocess.