IQUIBICEN 23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Novel respirable nanomicelles for encapsulation of anti-tuberculous rifampicin
Autor/es:
GROTZ, ESTEFANIA; BERNABEU EZEQUIEL; MANCONI, MARIA; AMIANO N.; MANCA, MARIA L.; MORETTON, MARCELA; TATEOSIAN N.; GONZALEZ, LORENA; CHIAPPETA, DIEGO
Lugar:
Buenos Aires
Reunión:
Congreso; IV International Congress in Translational Medicine; 2018
Institución organizadora:
International Master Program in Biomedical Sciences (IMBS)
Resumen:
We could succesufully developa nanocarrier based on RIFloaded Soluplus® micelles withimproved drug apparentsolubility and stability. Ournanotechnological platformexhibited the potential of beingadministered by the respiratoryroute due to its aerodynamicbehavior and also presented invitro microbicidal activityagainst Mtb ΔRD1. In thisframework, this nano-drugdelivery system represents afeasible strategy to beemployed as an adjuvantinhalatory therapy to theconventional oral anti-TBtreatment.
