IQUIBICEN 23947
INSTITUTO DE QUIMICA BIOLOGICA DE LA FACULTAD DE CIENCIAS EXACTAS Y NATURALES
Unidad Ejecutora - UE
artículos
Título:
Advances in drug delivery, gene delivery and therapeutic agents based on dendritic materials
Autor/es:
GARCIA, CYBELE; D'ACCORSO, NORMA; DOBRECKY, CECILIA; CONTIN, MARIO; LUCANGIOLI, SILVIA
Revista:
Future Medicinal Chemistry
Editorial:
Future Medicine Ltd.
Referencias:
Año: 2019 vol. 11 p. 1791 - 1810
ISSN:
1756-8919
Resumen:
Dendrimers are synthetic polymers that grow in three dimensions into well-defined structures. Their morphological appearance resembles a number of trees connected by a common point. Dendritic nanoparticles have been studied for a large number of pharmaceutical and biomedical applications including gene and drug delivery, clinical diagnosis and MRI. Despite the application of dendrimers, research is still in its childhood in comparison with liposomes and other nanomaterials. They are now playing a key role in several therapeutic strategies, with dendrimer-based products in clinical trials. The aim of this review is to describe the state-of-the-art of biomedical applications of dendrimers-and dendrimer conjugates-such as drug and gene delivery and antiviral activity.
