INVESTIGADORES
LEONARDI Dario
congresos y reuniones científicas
Título:
Chagas disease. Hydrophilic polymers applied to enhance the solubility of Benznidazole
Autor/es:
BOMBARDIERE, M.E.; LEONARDI, D.; SALOMÓN, C.J.
Lugar:
Cordoba, Argentina
Reunión:
Congreso; I Reunión internacional de Ciencias Farmacéuticas (Ricifa).; 2010
Institución organizadora:
Universidades de Córdoba y Rosario
Resumen:
Chagas disease is a major cause of morbidity and mortality in Latin America. Actually,it is also an emerging opportunistic infection among immunocompromised patients. One of the chosen drugs to treat this infection is benznidazole (BZL). The unique formulation available is a tablet of 100 mg and, however, despite of the growing incidence in pediatric populations, there is not any BZL liquid formulation. Therefore, in this work, different polymers were evaluated as carrier for improving the solubility of BZL, in order to preformulate liquid dosage forms of that compound.
