IGEVET   21075
INSTITUTO DE GENETICA VETERINARIA "ING. FERNANDO NOEL DULOUT"
Unidad Ejecutora - UE
artículos
Título:
Comparison of the effectiveness between microsatellites and SNP panels for parentage and genetic identification in an inbred Angus herd
Autor/es:
FERNANDEZ M E; GOSZCZYNSKI D E; LIRON J P; VILLEGAS CASTAGNASSO E E; CARINO M H; RIPOLI M V; ROGBERG MUÑOZ A; POSIK D M; PERAL GARCIA P; GIOVAMBATTISTA G
Revista:
GENETICS AND MOLECULAR BIOLOGY
Editorial:
SOC BRASIL GENETICA
Referencias:
Año: 2012 vol. 36
ISSN:
1415-4757
Resumen:
For Review O During the last decade, microsatellites (STRs, Short Tandem Repeats) have been successfully used in animal genetic identification, traceability and paternity, although.in the last few years single nucleotide polymorphisms (SNPs) have increased popularity. An efficient SNP identification system requires a marker set with enough power to identify individuals and their parents. Usually, genetic diagnostics include the analysis of related animals. In this work, the degree of information obtained through SNPs versus STRs within a consanguineous herd was compared. Thirty6six closely related Angus were genotyped for 18 STRs and 116 SNPs. Cumulative SNPs exclusion power values (Q) for paternity, and sample matching (MP) resulted higher than 0.9998 and 4.32E642, respectively. Between 2 and 3 SNPs per STR were needed to obtain an equivalent Q value. MP showed that 24 SNPs are equivalent to the 12 STRs ISAG (International Society for Animal Genetics) minimal recommended set (MP~10611). These results provide very valuable genetic data that supports the consensus SNP panel for bovine genetic identification developed by the Parentage Recording Working Group of ICAR (International Committee for Animal Recording).