MAST CELL HOMING IN CONNECTIVE TISSUES OF THE TONGUE

ZAVALA, W; FOSCOLO, M; DAVILA, J; CAVICCHIA, JC

MENDOZA, ARGENTINA

Congreso; XXVI REUNION CIENTIFICA ANUAL. SOCIEDAD DE BIOLOGIA DE CUYO; 2009

SOCIEDAD DE BIOLOGÍA DE CUYO. MENDOZA. ARGENTINA

185. MAST CELL HOMING IN CONNECTIVE TISSUES OF THE TONGUE IN NEWBORN RATS Zavala W, Foscolo M, Davila J, Cavicchia J. IHEM, Facultad Odontología. Univ Nac Cuyo. E-mail: wzavala@fodonto.uncu.edu.ar Mast cells (MC) are predominantly localized at the interface between host and environment such as skin and mucosal surfaces. They are able to perceive a variety of allergens and invading pathogens. In oral tissues, degranulation of mast cells has been a consistent feature of inflammatory lesion like liquen planus, gingivitis, periapical process and tumoral responsive. The aim of the present study is to describe the morphology and establish the homing time in connective tongue tissue of the rats. Tongue sections were collected from Wistar rats processed and included in paraffin wax, cut and stained with toluide blue and alcian blue-safranin. The total number of mast cell was counted to estimate the population density (mm2). Results showed morphology changes and number variations between the first week and the second week samples, after birth (p<0.001). These data suggest a quick MC adaptation and strategic location that allow react against different oral antigens. More studies are necessary to elucidate this phenomenon. A76 AUATBHSOTR A ICNTDSEX BIOCELL, 34(1) 2010