MAS CELL IN MAYOR SALIVARY GLANDS

ZAVALA, W; FOSCOLO, M; DAVILA, J; CAVICCHIA, JC

MENDOZA, ARGENTINA

Congreso; XXVI REUNION CIENTIFICA ANUAL. SOCIEDAD DE BIOLOGIA DE CUYO; 2008

SOCIEDAD DE BIOLOGÍA DE CUYO. MENDOZA. ARGENTINA

Mast cell in rat mayor salivary glands Zavala W, Foscolo M, Davila J, Cavicchia J. IHEM, Facultad Odontología Univ Nac Cuyo. E mail: waltherzavala@gmail.com Mast cells are predominantly localized at the interface between host and environment such as skin and mucosal surfaces. They are able to perceive a variety of allergens and invading pathogens. In oral tissues, degranulation of mast cells it has been a consistent feature of inflammatory lesion like liquen planus, gingivitis, and periapical process. Although the presence of mast cells in rat parotid has been reported, the distribution and role in normal condition remain still unknown. The aim of the present study was to find the number and the pattern of distribution and possible differences in mast cell population present in mayor salivary glands (parotid, sumandibular and sublingual glands) of rats. Fragments from salivary gland were collected, processed and included in paraffin wax, cut and stained with toluide blue and alcian blue-safranin. The total number of mast cell was counted to estimate the mm2 population from both intralobulillar and interlobulillar stroma tissues. Statistical analysis showed not significant differences (p< 0.05) among the three analysed glands. Numerous mast cells were located around salivary secretory ducts, in close association. The results suggest that MT play a relevant role in salivary antigen detection and there is a close cooperation with other antigen professional presenting cells like dendritic cells.