IHEM 20887
INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA DE MENDOZA DR. MARIO H. BURGOS
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Rat sperm rosettes: identification of epididymal proteins involved in sperm rosettes assembling
Autor/es:
MONCLUS MA; CABRILLANA M.E; CESARI A; VINCENTI A.E; FORNÉS M.W
Lugar:
Villa Carlos Paz, Cordoba. Argentina.
Reunión:
Congreso; XLIV Reunión Anual-Sociedad Argentina de Investigación en Bioquímica y Biología Molecular; 2008
Institución organizadora:
Sociedad Argentina de Investigación en Bioquímica y Biología Molecular (SAIB)
Resumen:
All fractions were tested by i.v. Rosettes test and the most active fraction (with MW from 40 to 80 KDa) and Concanavalin A affinity were analysed by MALDI-TOF-MS. Two proteins with serine protease inhibitor activity (serpins) were identified: a-1 Antitrypsin and a new protein with a a-1 Antitrypsin like domain. These results and previous indicate that Rosettes are assembled during the epididymal trip by several factors: sperm motility inhibition, linking proteins, proteases and their inhibitors.
